Peptide And Protein Drug Delivery
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Peptide And Protein Delivery
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Author : Chris Van Der Walle
language : en
Publisher: Academic Press
Release Date : 2011-05-12
Peptide And Protein Delivery written by Chris Van Der Walle and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-12 with Science categories.
The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide and Protein Delivery addresses the current and emerging routes for delivery of therapeutics. Covering cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery, this resource offers an overview of the main routes in therapeutics. Researchers across biochemistry, pharmaceutical, molecular biology, cell biology, immunology, chemistry and biotechnology fields will find this publication invaluable for peptide and protein laboratory research. Discusses the most recent data, ideas and concepts Presents case studies and an industrial perspective Details information from the molecular level to bioprocessing Thought provoking, for the novice to the specialist Timely, for today's biopharmaceuticals market
Peptide And Protein Drug Delivery
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Author : Vincent Lee
language : en
Publisher: CRC Press
Release Date : 1990-11-19
Peptide And Protein Drug Delivery written by Vincent Lee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-11-19 with Science categories.
This reference/text covers fundamentals of peptide and protein drug delivery, including such considerations as synthesis, physical chemistry and biochemistry, analysis, proteolytic and transport constraints, pharmacokinetics, and pharmacodynamics; bioavailability from routes of administration, detai
Trends And Future Perspectives In Peptide And Protein Drug Delivery
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Author : Vincent Lee
language : en
Publisher: CRC Press
Release Date : 1995-02-01
Trends And Future Perspectives In Peptide And Protein Drug Delivery written by Vincent Lee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-02-01 with Medical categories.
First published in 1995. Routledge is an imprint of Taylor & Francis, an informa company.
Peptide And Protein Drug Delivery
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Author :
language : en
Publisher: Munksgaard International Publishers
Release Date : 1998
Peptide And Protein Drug Delivery written by and has been published by Munksgaard International Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Drug delivery systems categories.
Peptide And Protein Drug Delivery Using Polysaccharides
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Author : Aakanchha Jain
language : en
Publisher: Elsevier
Release Date : 2023-10-10
Peptide And Protein Drug Delivery Using Polysaccharides written by Aakanchha Jain and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-10 with Science categories.
Peptide and Protein Drug Delivery Using Polysaccharides offers an interdisciplinary discussion of polysaccharides applied in peptide and protein drug delivery. Chapters consider basic biology of different polysaccharides of current interest and their production at pilot and large-scale stages by various techniques including, but not limited to, cell and hairy root cultures. Other sections examine factors affecting polysaccharide absorption, metabolism, and excretion in nascent, encapsulated, or conjugated forms, with unique coverage of vaccine absorption, metabolism, and drug delivery. A final section considers analytical methods for detection in tissue fluids and homogenates. Accessible figures, tables, and graphical abstracts are included throughout to support understanding. Specific polysaccharides discussed for therapeutic purposes include cellulose, hyaluronic acid, heparin, carageenan, alginic acid, agar and myrrh, acacia, tragacanth, ghatti gum, chitin, chitosan, starch, glycogen and dextran. Adopts an interdisciplinary approach across biochemistry, molecular biology, pharmaceutical sciences and drug delivery, and biotechnological perspectives Features accessible figures, tables and graphical abstracts across all chapters to support understanding Examines various polysaccharides of current interest and aspects affecting their absorption, metabolism, excretion and detection
Biological Barriers To Protein Delivery
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Author : Kenneth L. Andus
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Biological Barriers To Protein Delivery written by Kenneth L. Andus and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In response to the tremendous increase in the number of protein and peptide drugs, this treatise critically reviews transport and metabolism mechanisms relating to the delivery of endogenous and recombinant proteins to mammalian organs, tissues, and cells. It will promote fruitful collaboration among academic and industrial scientists in the fields of pharmacology, cell biology, biochemistry, physiology, and immunology.
Therapeutic Peptides And Proteins
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Author : Ajay K. Banga
language : en
Publisher: CRC Press
Release Date : 2015-04-23
Therapeutic Peptides And Proteins written by Ajay K. Banga and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-23 with Medical categories.
There are more than 500 biopharmaceuticals on the market, including more than 200 therapeutic proteins, making biologics the fastest growing sector in the biopharmaceutical market. These products include more than 40 monoclonal antibodies, for indications ranging from treatment or mitigation of various types of cancer to rheumatoid arthritis. The clinical application of these therapeutic peptides and proteins is limited by several problems, such as lack of physical and chemical stability or the lack of desirable attributes for adequate absorption or distribution. Thus, as these therapeutic peptides and proteins are made available, it will be essential to formulate these drugs into safe, stable, and efficacious delivery systems. The pharmaceutical scientist involved in this effort needs to call upon the knowledge of several disciplines, such as pharmaceutics, medicinal chemistry, biochemistry, microbiology, and chemical engineering and needs to keep abreast with the latest research in the published literature. Therapeutic Peptides and Proteins: Formulation, Processing, and Delivery Systems, Third Edition provides a comprehensive overview of the field for scientists in industry and academia and for students, while also providing practical information on the challenges facing the formulation and delivery aspects of these unique macromolecules. In particular, the book: Explains how recombinant DNA techniques now allow us to produce therapeutic proteins in a commercially viable form Discusses the physical and chemical pathways of peptide and protein degradation Includes a detailed discussion of protein formulation and lyophilization Overviews the pharmacokinetic aspects of therapeutic peptides and proteins and discusses controlled delivery systems for parenteral administration, including microsphere formulations Discusses research progress on oral, transdermal, mucosal, and topical delivery systems discusses transdermal and topical delivery
Proteins And Peptides
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Author : Randall J. Mrsny
language : en
Publisher: CRC Press
Release Date : 2009-10-19
Proteins And Peptides written by Randall J. Mrsny and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-19 with Medical categories.
Addressing the increased use of protein and peptide candidates as treatments for previously untreatable diseases, this comprehensive and progressive source provides the reader with a roadmap to an increased understanding of issues critical for successfully developing a protein or peptide therapeutic candidate. Proteins and Peptides is
Therapeutic Peptides And Proteins
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Author : Ajay K. Banga
language : en
Publisher: CRC Press
Release Date : 2005-09-14
Therapeutic Peptides And Proteins written by Ajay K. Banga and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-14 with Medical categories.
Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there were only 19 biotechology medicines on the market. Currently there are more than 100, with at least 400 more in various stages of development. That alone would be grounds for a new edition. Add to that the fact that it is still difficult to find up
Delivery Systems For Peptide Drugs
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Author : S.S. Davis
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Delivery Systems For Peptide Drugs written by S.S. Davis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
Recent years have seen enormous advances in the field of protein and peptide engineering and a greater understanding in the way in which biological response modifiers function in the body. It is now possible through the use of recombinant DNA techniques, or by solid phase protein synthesis, to produce significant quantities of a wide variety of regulatory agents that are therapeutically applicable. The list of these response modifiers expands almost daily to include interferons, macrophage activation factors, neuropeptides and agents that may have potential in cardiovascular disease, inflammation, contraception etc. Prospects to use some of these materials in medicine have reached the stage where products have either been approved by regulatory authorities or are the subject of applications as investigatory drugs or as new therapeutic agents. In some uses the pertinent agent will be administered on an acute basis in the form of a simple injection, as, for example, the use of a tissue plasminogen activator for the treatment of coronary infarct. In other cases regulatory proteins and peptides are indicated for chronic therapy and here they will need to be administered by an appropriate delivery system. Unfortunately, the research on delivery systems for peptides and proteins has not kept pace with the rapid progress in biotechnology and, consequently, there are presently few systems that are entirely appropriate for the administration of macromolecular drugs according to complex dosage regimens, (eg intermittent and pulsed therapy). Furthermore essential pharmacokinetic and pharmacodynamic data may be missing.