Perspectives In Nucleoside And Nucleic Acid Chemistry
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Perspectives In Nucleoside And Nucleic Acid Chemistry
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Author : M. Volkan Kisakürek
language : en
Publisher: John Wiley & Sons
Release Date : 2000
Perspectives In Nucleoside And Nucleic Acid Chemistry written by M. Volkan Kisakürek and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.
The chemistry of nucleosides and nucleic acids is a rapidly developing field. Many of the most important recent advances in medicinal chemistry have occured in this field with the development of novel nucleoside– and nucleotide–based antiviral and antitumor drugs. New synthesis strategies involving novel protecting groups have helped spur progress in drug–development and genome–sequencing research. This volume, comprised of contributions written by internationally recognized experts, covers cutting–edge developments in current nucleoside and nucleic acid research. The most recent synthesis innovations, including combinatorial approaches, spectroscopy and structural studies, thermodynamic and computational investigations, stability assessments, and medicinal applications are presented. Synthetic, physical, organic, bioorganic, and medicinal chemists working on all aspects of nucleoside and nucleic acid research will value this comprehensive state–of–the–art overview.
Nucleic Acids In Chemistry And Biology
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Author : G Michael Blackburn
language : en
Publisher: Royal Society of Chemistry
Release Date : 2015-11-09
Nucleic Acids In Chemistry And Biology written by G Michael Blackburn and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-09 with Science categories.
The structure, function and reactions of nucleic acids are central to molecular biology and are crucial for the understanding of complex biological processes involved. Revised and updated Nucleic Acids in Chemistry and Biology 3rd Edition discusses in detail, both the chemistry and biology of nucleic acids and brings RNA into parity with DNA. Written by leading experts, with extensive teaching experience, this new edition provides some updated and expanded coverage of nucleic acid chemistry, reactions and interactions with proteins and drugs. A brief history of the discovery of nucleic acids is followed by a molecularly based introduction to the structure and biological roles of DNA and RNA. Key chapters are devoted to the chemical synthesis of nucleosides and nucleotides, oligonucleotides and their analogues and to analytical techniques applied to nucleic acids. The text is supported by an extensive list of references, making it a definitive reference source. This authoritative book presents topics in an integrated manner and readable style. It is ideal for graduate and undergraduates students of chemistry and biochemistry, as well as new researchers to the field.
Enzymatic And Chemical Synthesis Of Nucleic Acid Derivatives
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Author : Jesús Fernández Lucas
language : en
Publisher: John Wiley & Sons
Release Date : 2019-04-29
Enzymatic And Chemical Synthesis Of Nucleic Acid Derivatives written by Jesús Fernández Lucas and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-29 with Science categories.
A review of innovative tools for creative nucleic acid chemists that open the door to novel probes and therapeutic agents Nucleic acids continue to gain importance as novel diagnostic and therapeutic agents. With contributions from noted scientists and scholars, Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives is a practical reference that includes a wide range of approaches for the synthesis of designer nucleic acids and their derivatives. The book covers enzymatic (including chemo-enzymatic) methods, with a focus on the synthesis and incorporation of modified nucleosides. The authors also offer a review of innovative approaches for the non-enzymatic chemical synthesis of nucleic acids and their analogs and derivatives, highlighting especially challenging species. The book offers a concise review of the methods that prepare novel and heavily modified polynucleotides in sufficient amount and purity for most clinical and research applications. This important book: -Presents a timely and topical guide to the synthesis of designer nucleic acids and their derivatives -Addresses the growing market for nucleotide-derived pharmaceuticals used as anti-infectives and chemotherapeutic agents, as well as fungicides and other agrochemicals. -Covers novel methods and the most recent trends in the field -Contains contributions from an international panel of noted scientistics Written for biochemists, medicinal chemists, natural products chemists, organic chemists, and biotechnologists, Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives is a practice-oriented guide that reviews innovative methods for the enzymatic as well as non-enzymatic synthesis of nucleic acid species.
Reactions And Syntheses
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Author : Lutz F. Tietze
language : en
Publisher: John Wiley & Sons
Release Date : 2015-02-23
Reactions And Syntheses written by Lutz F. Tietze and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-23 with Science categories.
The second edition of this classic text book has been completely revised, updated, and extended to include chapters on biomimetic amination reactions, Wacker oxidation, and useful domino reactions. The first-class author team with long-standing experience in practical courses on organic chemistry covers a multitude of preparative procedures of reaction types and compound classes indispensable in modern organic synthesis. Throughout, the experiments are accompanied by the theoretical and mechanistic fundamentals, while the clearly structured sub-chapters provide concise background information, retrosynthetic analysis, information on isolation and purification, analytical data as well as current literature citations. Finally, in each case the synthesis is labeled with one of three levels of difficulty. An indispensable manual for students and lecturers in chemistry, organic chemists, as well as lab technicians and chemists in the pharmaceutical and agrochemical industries.
Modified Nucleic Acids
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Author : Kazuhiko Nakatani
language : en
Publisher: Springer
Release Date : 2016-04-04
Modified Nucleic Acids written by Kazuhiko Nakatani and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-04 with Science categories.
This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.
Chemistry Of Nucleic Acids
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Author : Harri Lönnberg
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2020-08-10
Chemistry Of Nucleic Acids written by Harri Lönnberg and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-10 with Science categories.
Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses the main aspects of synthesis, hydrolytic stability, solution equilibria of nucleosides and nucleotides as well as base modifications of nucleic acids. The author further describes their structural analogues used as therapeutic drugs, such as antivirals and anticancer agents, and prodrug strategies of nucleotides.
Supramolecular Nucleic Acid Chemistry
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Author : James Tucker
language : en
Publisher: Frontiers Media SA
Release Date : 2020-10-28
Supramolecular Nucleic Acid Chemistry written by James Tucker and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-28 with Science categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Handbook Of Chemical Biology Of Nucleic Acids
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Author : Naoki Sugimoto
language : en
Publisher: Springer Nature
Release Date : 2023-07-29
Handbook Of Chemical Biology Of Nucleic Acids written by Naoki Sugimoto and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-29 with Science categories.
This handbook is the first to comprehensively cover nucleic acids from fundamentals to recent advances and applications. It is divided into 10 sections where authors present not only basic knowledge but also recent research. Each section consists of extensive review chapters covering the chemistry, biology, and biophysics of nucleic acids as well as their applications in molecular medicine, biotechnology and nanotechnology. All sections within this book are: Physical Chemistry of Nucleic Acids (Section Editor: Prof. Roland Winter), Structural Chemistry of Nucleic Acids (Section Editor: Prof. Janez Plavec), Organic Chemistry of Nucleic Acids (Section Editor: Prof. Piet Herdewijin), Ligand Chemistry of Nucleic Acids (Section Editor: Prof. Marie-Paule Teulade-Fichou), Nucleic Acids and Gene Expression (Section Editor: Prof. Cynthia Burrows), Analytical Methods and Applications of Nucleic Acids (Section Editor: Prof. Chaoyong Yang), Nanotechnology and Nanomaterial Biology of Nucleic Acids (Section Editor: Prof. Zhen Xi), Nucleic Acids Therapeutics (Section Editor: Prof. Katherine Seley-Radtke), Biotechnology and Synthetic Biology of Nucleic Acids (Section Editor: Prof. Eriks Rozners), Functional Nucleic Acids (Section Editor: Prof. Keith R. Fox). The handbook is edited by outstanding leaders with contributions written by international renowned experts. It is a valuable resource not only for researchers but also graduate students working in areas related to nucleic acids who would like to learn more about their important role and potential applications.
Reagents For Glycoside Nucleotide And Peptide Synthesis
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Author : David Crich
language : en
Publisher: Wiley
Release Date : 2005-10-21
Reagents For Glycoside Nucleotide And Peptide Synthesis written by David Crich and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-21 with Science categories.
This handbook collects together short, informative articles on approximately 250 of the most widely used reagents in the field, into a single volume. Each of the articles, drawn from the e-EROS database, contains a summary of the most pertinent reactions for every reagent, with references to the original literature. This handbook will have a broad appeal and should find a home in every organic chemistry laboratory and library. Compiles all the essential reagents for syntheses on and with biomolecules Gives key information on protection, bond formation and deprotection An essential resource for all synthetic chemists working in drug development and medicinal chemistry Makes use of the leading reagent database e-EROS
European Journal Of Inorganic Chemistry
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Author :
language : en
Publisher:
Release Date : 2001
European Journal Of Inorganic Chemistry written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Bioinorganic chemistry categories.