Phagocytosis Promotes Programmed Cell Death And Is Controlled By Rac Signaling Pathway In C Elegans
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Phagocytosis Promotes Programmed Cell Death And Is Controlled By Rac Signaling Pathway In C Elegans
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Author : Peter Walthour Reddien
language : en
Publisher:
Release Date : 2002
Phagocytosis Promotes Programmed Cell Death And Is Controlled By Rac Signaling Pathway In C Elegans written by Peter Walthour Reddien and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.
(Cont.) We found that ced-l0 Rac is the primary Rac gene required for engulfment but acts redundantly with the mig-2 Rac-like gene and independently from ced-2 and ced-5 to control neuronal migration and axon pathfinding. We suggest Rac genes can be differentially utilized and regulated for different developmental events. We identified two new genes that promote programmed cell death from a genetic screen. The first, dpl-i, encodes a protein similar to human DP, which is the heterodimerization partner for the transcription factor E2F. The second, mcd-l, encodes a novel Zn finger-containing protein. dpl-l and mcd-l act downstream of the cell death inhibitory gene ced-9 to promote cell death.
Bacterial Virulence Factors And Rho Gtpases
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Author : Patrice Boquet
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-04-01
Bacterial Virulence Factors And Rho Gtpases written by Patrice Boquet and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-04-01 with Medical categories.
Pathogenic bacteria for human and animals have developed sophisticated weapons, termed virulence factors, to ensure their replication and persistence into their hosts. The authors in this volume show a synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfil their virulence.
The Nematode Caenorhabditis Elegans
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Author : William Barry Wood
language : en
Publisher:
Release Date : 1988
The Nematode Caenorhabditis Elegans written by William Barry Wood and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Science categories.
Phagocytosis Of Dying Cells
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Author : Dmitri V. Krysko
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-03-10
Phagocytosis Of Dying Cells written by Dmitri V. Krysko and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-10 with Medical categories.
Phagocytosis has been at the forefront of cell biology for more than a century. Initially, phagocytosis, which comes from Greek words meaning “devouring cells,” was discovered in the late 19th century by Ilya Metchnikoff, who was awarded, together with Paul Ehrlich, the Nobel Prize in Physiology and Medicine in 1908 “in recognition of their work on immunity.” At that time Metchnikoff had already identified a function for phagocytes not only in host defense but also as scavengers of degenerating host cells during metamorphosis of tadpoles, thus providing one of the first descriptions of apoptotic cell clearance by macrophages (Kaufmann 2008). Since then, much has been learned about phagocytosis, and the previous several decades have witnessed outstanding progress in understanding the functions and the molecular mechanisms of phagocytosis. Two main types of targets are cleared by phagocytosis: microbial pathogens and dying cells. Rapid recognition and clearance of dying cells by phagocytes plays a pivotal role in development, maintenance of tissue homeostasis, control of immune responses, and resolution of inflammation. Clearance of dying cells can be divided into several stages, including sensing, r- ognition, binding and signaling, internalization, and immunological responses. In this book, our contributors address these different stages of dead cell cle- ance and examine how impaired clearance of dying cells may lead to human d- eases. We have attempted to provide sufficient cross-referencing and indexing to enable the reader to easily locate the ideas elaborated in the different chapters.
Essentials Of Apoptosis
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Author : Xiao-Ming Yin
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-07-01
Essentials Of Apoptosis written by Xiao-Ming Yin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-01 with Science categories.
This is the second edition of the comprehensive, concise summary of apoptosis research. It covers the major concepts, molecular architecture, the biochemical pathways, and pathophysiological significance of apoptosis. This book provides a guideline of standard biochemical and cell biologic approaches to apoptosis bench work with an emphasis on translational clinical applications for immune disorders, cancer research, ischemia, and neuronal degeneration. Since the original publication in 2003, the apoptosis field has expanded rapidly – chapters not only need to be revised and expanded, but there is a need for all new chapters covering exciting advances in bioinformatics, systems biology, oxidative stress, etc.
Mechanisms Of Cell Death
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Author : Zahra Zakeri
language : en
Publisher:
Release Date : 1999
Mechanisms Of Cell Death written by Zahra Zakeri and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Science categories.
Contains papers from a July 1998 conference held at the Queens College Campus of the City University of New York. Papers are arranged in sections on mechanisms and general considerations, programmed (developmental) cell death, and cell death and pathological and clinical situations. Specific topics
Dissertation Abstracts International
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Author :
language : en
Publisher:
Release Date : 2008
Dissertation Abstracts International written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Dissertations, Academic categories.
Apoptosis And Development
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-10-05
Apoptosis And Development written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-05 with Science categories.
Apoptosis and Development, the latest volume of Current Topics in Developmental Biology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis and development, and includes sections on such topics as the non-lethal role of apoptotic proteins and germ line cell death in Drosophila. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Includes descriptions of the most recent advances in the field Covers research methods in apoptosis and development, and includes sections on such topics as the non-lethal role of apoptotic proteins and germ line cell death in Drosophila
Nematode Models Of Development And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-05-13
Nematode Models Of Development And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-13 with Science categories.
Nematode Models of Development and Disease, Volume 144 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters surrounding Transgenerational inheritance, Oscillatory expression and function, Concepts and functions of small RNA pathways in C. elegans, Exploring the nuclear lamina in health and pathology using C. elegans, Cellular Plasticity, Morphogenesis, Tubulogenesis, Organogenesis forces, Programmed cell fusion in development and homeostasis, One template, two outcomes: how does the sex-shared nervous system generate sex-specific behaviors?, Metabolic Cellular Coordination of Gene-Environment Interactions, and much more. Other chapters cover Chemical and physical cues and micro-evolution in early embryogenesis, Innate immunity, Sex and Death, Dendrites maturation, axonal growth and extracellular glycoproteins, Autophagocytosis, Spermatogenesis, and the developmental and physiological roles of phagocytosis in Caenorhabditis elegans. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology
Mitochondrial Dysfunction
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Author : Lawrence H. Lash
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Mitochondrial Dysfunction written by Lawrence H. Lash and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.