Essentials Of Apoptosis
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Essentials Of Apoptosis
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Author : Xiao-Ming Yin
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-07-01
Essentials Of Apoptosis written by Xiao-Ming Yin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-01 with Science categories.
This is the second edition of the comprehensive, concise summary of apoptosis research. It covers the major concepts, molecular architecture, the biochemical pathways, and pathophysiological significance of apoptosis. This book provides a guideline of standard biochemical and cell biologic approaches to apoptosis bench work with an emphasis on translational clinical applications for immune disorders, cancer research, ischemia, and neuronal degeneration. Since the original publication in 2003, the apoptosis field has expanded rapidly – chapters not only need to be revised and expanded, but there is a need for all new chapters covering exciting advances in bioinformatics, systems biology, oxidative stress, etc.
Essentials Of Apoptosis
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Author : Xiao-Ming Yin
language : en
Publisher:
Release Date : 2003
Essentials Of Apoptosis written by Xiao-Ming Yin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Apoptosis categories.
Essentials Of Apoptosis
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Author : Xiao-Ming Yin
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-02-27
Essentials Of Apoptosis written by Xiao-Ming Yin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-02-27 with Science categories.
Basic and clinical investigators systematically compile a comprehensive but concise summary of essential, up-to-date information about apoptosis. The authors present the concepts, the molecular architecture, the biochemical pathways, and the pathophysiological significance of apoptosis. In addition, standard biochemical and cell biologic approaches to apoptosis research are described as a guideline for bench work, with clinical applications detailed for immune disorders, cancer, ischemia/reperfusion injury, and neuronal degeneration.
Biochemistry Of Apoptosis And Autophagy
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Author : Lorrie A. Kirshenbaum
language : en
Publisher: Springer Nature
Release Date : 2021-11-29
Biochemistry Of Apoptosis And Autophagy written by Lorrie A. Kirshenbaum and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-29 with Science categories.
One of the most intriguing and compelling issues to impact contemporary biology to date is the concept that cell death is genetically regulated. Observations by Kerr and Wyllie, made more than 30 years ago on the basis of distinct morphological criteria, markedly distinguished apoptosis from classical cell death by necrosis. Apoptosis is a highly regulated, evolutionary conserved, genetic program of cell death essential for normal development and tissue homeostasis. The discovery of apoptosis as a regulated event and potentially amenable to therapeutic interventions has generated considerable excitement because it meant that disease entities resulting from either too much, or too little, apoptosis could be potentially cured with new therapies that target apoptosis. While there is little doubt that necrosis induced by massive cellular trauma is likely an unregulated event, several lines of investigation have challenged the dogma that necrotic cell death is merely unregulated. Emerging data has shifted the paradigm in our thinking about necrosis as a regulated event. Autophagy is another cellular process that has received considerable attention over the past two decades and its remarkable involvement in the processes of cell survival, death and tumorigenesis. Macro autophagy is a catabolic process that involves the selective and targeted removal of oxidized proteins, macromolecular structures and organelles through an elaborate cellular process involving a lysosome mediated pathway. Other forms of autophagy involving adapter proteins, commonly referred to as chaperone mediated autophagy, involves the selective removal of cellular cargo by the ubiquitin-proteasome pathway. The book will serve as a reference guide for basic and clinical scientists who are interested in understanding how these critical cellular processes impact the pathogenesis of human disease.
Apoptosis In Cancer Pathogenesis And Anti Cancer Therapy
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Author : Christopher D. Gregory
language : en
Publisher: Springer
Release Date : 2016-08-24
Apoptosis In Cancer Pathogenesis And Anti Cancer Therapy written by Christopher D. Gregory and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-24 with Medical categories.
This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews. Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.
Current Understanding Of Apoptosis
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Author : Yusuf Tutar
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-08-29
Current Understanding Of Apoptosis written by Yusuf Tutar and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-29 with Science categories.
Apoptosis is an essential biochemical process in cell turnover, development, and chemical-induced cell death. Current knowledge and ongoing research of apoptosis highlight our understanding in designing the therapeutic approaches for several diseases. This book covers four main sections: "Apoptosis and Necrosis," "Apoptosis Inducers," "Proteasome and Signaling Pathways in Apoptosis," and "Radiation-Based Apoptosis." The first section implicitly describes the differences between apoptosis and necrosis processes. The following section elaborates the small molecule-induced apoptosis. Then, the third section deals with proteasome and signaling pathways and finally, resistance to chemotherapy and electromagnetic radiation is covered in the last section. Overall, the book deals with pathways for manipulating apoptosis and provides a unique perspective to the scientists.
Cell Death
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Author : Douglas R. Green
language : en
Publisher:
Release Date : 2018
Cell Death written by Douglas R. Green and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Science categories.
A million cells in our bodies die every second--they commit suicide by activating a process called apoptosis or other forms of programmed cell death. These mechanisms are essential for survival of the body as a whole and play critical roles in various developmental processes, the immune system, and cancer. In this second edition of Douglas Green's essential book on cell death, Green retains the bottom-up approach of the first edition, starting with the enzymes that carry out the execution (caspases) and their cellular targets before examining the machinery that connects them to signals that cause cell death. He also describes the roles of cell death in development, neuronal selection, and the development of self-tolerance in the immune system, as well as how the body uses cell death to defend against cancer. The new edition is fully updated to cover the many recent advances in our understanding of the death machinery and signals that control cell death. These include the mechanisms regulating necroptosis, mitophagy, and newly identified processes, such as ferroptosis. The book will thus be of great interest to researchers actively working in the field, as well as biologists and undergraduates encountering the topic for the first time.
Self And Nonself
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Author : Carlos López-Larrea
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-03-07
Self And Nonself written by Carlos López-Larrea and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-07 with Medical categories.
In 1960 Sir Frank Macfarlane Burnet received the Noble Prize in Physiology and Medicine. He titled his Nobel Lecture “Immunological Recognition of Self” emphasizing the central argument of immunological tolerance in “How does the vertebrate organism recognize self from nonself in this the immunological sense—and how did the capacity evolve.” The concept of self is linked to the concept of biological self identity. All organisms, from bacteria to higher animals, possess recognition systems to defend themselves from nonself. Even in the context of the limited number of metazoan phyla that have been studied in detail, we can now describe many of the alternative mechanism of immune recognition that have emerged at varying points in phylogeny. Two different arms—the innate and adaptive immune system—have emerged at different moments in evolution, and they are conceptually different. The ultimate goals of immune biology include reconstructing the molecular networks underlying immune processes.
Apoptosis
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Author : Douglas R. Green
language : en
Publisher: Cambridge University Press
Release Date : 2011-08-22
Apoptosis written by Douglas R. Green and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-22 with Science categories.
Apoptosis, or cell death, can be pathological, a sign of disease and damage, or physiological, a process essential for normal health. This book, with contributions from experts in the field, provides a timely compilation of reviews of mechanisms of apoptosis. The book is organized into three convenient sections. The first section explores the different processes of cell death and how they relate to one another. The second section focuses on organ-specific apoptosis-related diseases. The third section explores cell death in non-mammalian organisms, such as plants. This comprehensive text is a must-read for all researchers and scholars interested in apoptosis.
Essentials Of Cell Biology
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Author : Dr. Amit Joshi
language : en
Publisher: Orangebooks Publication
Release Date : 2023-01-01
Essentials Of Cell Biology written by Dr. Amit Joshi and has been published by Orangebooks Publication this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-01 with Education categories.
This book “Essentials of Cell biology” is based on the idea that a cell is the basic building block of all life forms. Here author highlighted the information about cellular make up, functionality and fundamentals of cellular biochemistry. It is a detailed text book focusing on cell biology. This book will assist UG, PG, and Research students. It is designed Unit wise and chapter wise to involve all the aspects of cell biology. Cell biology is necessary for all the Life Sciences domains like Biotechnology, Biochemistry, Microbiology, Bioinformatics, Zoology, and Botany.