Current Understanding Of Apoptosis
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Current Understanding Of Apoptosis
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Author : Yusuf Tutar
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-08-29
Current Understanding Of Apoptosis written by Yusuf Tutar and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-29 with Science categories.
Apoptosis is an essential biochemical process in cell turnover, development, and chemical-induced cell death. Current knowledge and ongoing research of apoptosis highlight our understanding in designing the therapeutic approaches for several diseases. This book covers four main sections: "Apoptosis and Necrosis," "Apoptosis Inducers," "Proteasome and Signaling Pathways in Apoptosis," and "Radiation-Based Apoptosis." The first section implicitly describes the differences between apoptosis and necrosis processes. The following section elaborates the small molecule-induced apoptosis. Then, the third section deals with proteasome and signaling pathways and finally, resistance to chemotherapy and electromagnetic radiation is covered in the last section. Overall, the book deals with pathways for manipulating apoptosis and provides a unique perspective to the scientists.
Molecular Biology Of The Cell
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Author :
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cells categories.
Apoptosis And Cancer
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Author : Seamus J. Martin
language : en
Publisher: R G Landes Company
Release Date : 1997
Apoptosis And Cancer written by Seamus J. Martin and has been published by R G Landes Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.
Apoptosis Cell Signaling And Human Diseases
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Author : Rakesh Srivastava
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-05
Apoptosis Cell Signaling And Human Diseases written by Rakesh Srivastava and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-05 with Science categories.
These volumes present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways. Particular attention is given to apoptosis in human diseases, such as different forms of cancer and neurodegenerative diseases. These comprehensive volumes integrate the most innovative and current findings from several related disciplines of scientific research, including pathology, genetics, virology, cell biology, immunology, and molecular biology.
Self And Nonself
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Author : Carlos López-Larrea
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-03-07
Self And Nonself written by Carlos López-Larrea and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-07 with Medical categories.
In 1960 Sir Frank Macfarlane Burnet received the Noble Prize in Physiology and Medicine. He titled his Nobel Lecture “Immunological Recognition of Self” emphasizing the central argument of immunological tolerance in “How does the vertebrate organism recognize self from nonself in this the immunological sense—and how did the capacity evolve.” The concept of self is linked to the concept of biological self identity. All organisms, from bacteria to higher animals, possess recognition systems to defend themselves from nonself. Even in the context of the limited number of metazoan phyla that have been studied in detail, we can now describe many of the alternative mechanism of immune recognition that have emerged at varying points in phylogeny. Two different arms—the innate and adaptive immune system—have emerged at different moments in evolution, and they are conceptually different. The ultimate goals of immune biology include reconstructing the molecular networks underlying immune processes.
Cell Death
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Author : Douglas R. Green
language : en
Publisher:
Release Date : 2018
Cell Death written by Douglas R. Green and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Science categories.
A million cells in our bodies die every second--they commit suicide by activating a process called apoptosis or other forms of programmed cell death. These mechanisms are essential for survival of the body as a whole and play critical roles in various developmental processes, the immune system, and cancer. In this second edition of Douglas Green's essential book on cell death, Green retains the bottom-up approach of the first edition, starting with the enzymes that carry out the execution (caspases) and their cellular targets before examining the machinery that connects them to signals that cause cell death. He also describes the roles of cell death in development, neuronal selection, and the development of self-tolerance in the immune system, as well as how the body uses cell death to defend against cancer. The new edition is fully updated to cover the many recent advances in our understanding of the death machinery and signals that control cell death. These include the mechanisms regulating necroptosis, mitophagy, and newly identified processes, such as ferroptosis. The book will thus be of great interest to researchers actively working in the field, as well as biologists and undergraduates encountering the topic for the first time.
Innovative Medicine
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Author : Kazuwa Nakao
language : en
Publisher: Springer
Release Date : 2015-10-13
Innovative Medicine written by Kazuwa Nakao and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-13 with Science categories.
This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
Apoptosis And Cancer Chemotherapy
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Author : John A. Hickman
language : en
Publisher: Springer Science & Business Media
Release Date : 1999-04-08
Apoptosis And Cancer Chemotherapy written by John A. Hickman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-04-08 with Medical categories.
The past few years have witnessed an astonishing international effort that established the role of some 20 new molecules in apoptosis and added activation or suppression of apoptosis to the accepted biological functions of a great many others already familiar in cancer biology. Some of these molecules are receptors, transducing cytokine-mediated signals; others appear to intensify or diminish the risk that a compro mised cell will fire its apoptosis effector mechanism. All are of interest as potential targets for tumor therapy, and some may prove to be control points influenced in the pathogenesis of cancer and other diseases as diverse as viral infection, neurodegenerative disorders, and stroke. Sometimes, in the midst of these developments, a kind of euphoria ap pears to have gripped the research community, with the expectation that apoptosis will afford explanations to many unsolved questions in cellu lar regulation. This book, in a series of thoughtful and provocative ar ticles--some from established leaders in the field, and others from younger scientists--seeks to redress the balance.
Apoptosis
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Author : Douglas R. Green
language : en
Publisher: Cambridge University Press
Release Date : 2011-08-22
Apoptosis written by Douglas R. Green and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-22 with Science categories.
Apoptosis, or cell death, can be pathological, a sign of disease and damage, or physiological, a process essential for normal health. This book, with contributions from experts in the field, provides a timely compilation of reviews of mechanisms of apoptosis. The book is organized into three convenient sections. The first section explores the different processes of cell death and how they relate to one another. The second section focuses on organ-specific apoptosis-related diseases. The third section explores cell death in non-mammalian organisms, such as plants. This comprehensive text is a must-read for all researchers and scholars interested in apoptosis.