Pharmaceutical Applications Of Supramolecules
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Pharmaceutical Applications Of Supramolecules
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Author : Nidhi Goel
language : en
Publisher: Springer Nature
Release Date : 2023-01-16
Pharmaceutical Applications Of Supramolecules written by Nidhi Goel and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-16 with Science categories.
This book outlines the use of supramolecules as different pharmaceutical drugs. Supramolecular chemistry in pharmaceutical sciences is quite a young and rapidly developing field. Supramolecular assemblies might offer an alternative for existing pharmaceutical formulations, as they facilitate the improvement of physicochemical and pharmacological properties i.e., higher bioavailability, better biocompatibility and drug-targeting, fewer multidrug-resistances. This book offers an overview of the recent advances in supramolecular structures and discusses the future aspects and challenges related to the development of these molecules, providing also a perspective on how to overcome these issues. Divided into 13 chapters contributed by experts in their field, the book provides a deeper understanding of intermolecular forces playing pivotal roles in mediating the interactions between chemical molecules and biological systems by focusing on different applications of supramolecular compounds. In this book, readers will find valuable insights into the preparation of supramolecules and the latest research and development trends of supramolecules as anticancer drugs, including liquid-crystalline supramolecular assemblies, and as antimicrobial, antiviral, anti-inflammatory and cardiovascular drugs. Particular attention is given to the application of supramolecules in the fields of biomedicine, bioimaging, and vaccine development. Given its breadth, this book will appeal to a wide readership from researchers and students interested in these fields to professionals in the pharma industry.
Supramolecular Nanomaterials For Engineering Drug Delivery And Medical Applications
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Author : Yohann Corvis
language : en
Publisher: Frontiers Media SA
Release Date : 2021-01-21
Supramolecular Nanomaterials For Engineering Drug Delivery And Medical Applications written by Yohann Corvis and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-21 with Science categories.
Supramolecular Systems In Biomedical Fields
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Author : Hans-Jorg Schneider
language : en
Publisher: Royal Society of Chemistry
Release Date : 2013-09-06
Supramolecular Systems In Biomedical Fields written by Hans-Jorg Schneider and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-06 with Science categories.
Non-covalent interactions, which are the heart of supramolecular chemistry are also the basis of most important functions of living systems. The ability to apply supramolecular chemistry principles to the life sciences, such as designing synthetic host compounds to selectively interact within biological targets, has gained wide appeal due the vast number of potential applications. Supramolecular Systems for Biomedical Fields provides in sixteen chapters a comprehensive overview of these applications. Each chapter covers a specific topic and is written by internationally renowned experts in that area. Sensing of bioactive inorganic ions and organic substrates is the focus of several contributions, as well as interactions with proteins and nucleic acids. Specific chapters are devoted to cyclodextrins, calixarenes and cucurbiturils as most frequently used receptors, including applications such as drug delivery and protection, gene transfer and others. Other chapters address the use of combinatorial libraries, molecular imprinting techniques, enzyme assays, supramolecular gels, bioimaging, drug activation, photodynamic therapy, and antitumour metal complexes. This timely publication will appeal to graduate students and researchers from chemical, pharmaceutical, biological, and medicinal fields interested in the supramolecular chemistry of biological systems and their practical potentials.
New Trends In Macromolecular And Supramolecular Chemistry For Biological Applications
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Author : Marc J.M. Abadie
language : en
Publisher: Springer Nature
Release Date : 2021-05-26
New Trends In Macromolecular And Supramolecular Chemistry For Biological Applications written by Marc J.M. Abadie and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-26 with Medical categories.
This contributed volume applies the insights of supramolecular chemistry to biomedical applications such as ions/water transport through nano-scale channels, gene therapy, tissue engineering and drug delivery, to cite some of the major investigations.The challenge is to understand the mechanisms of transport through tissues particularly in the therapeutic treatment of a disease where the active drug must be delivered directly to diseased cells without affecting healthy cells. As a result, smaller quantities of active substances can be used to treat the disease. Another interest concerns new ways to administer gene therapy. If genes are often delivered to their target cells by adapted viruses, the supramolecular non-viral ‘vectors’ using dynamic nano-frameworks and nano-structures are presented. In addition, it is important to reconstruct damaged tissues by mimicking natural processes in cells and polymers, such as tissue engineering and self-healing. Different options are here discussed: e.g. hydrogels based on chitosan, a carbohydrate polymer, are proving especially promising for tissue engineering and drug delivery. For controlled delivery of drugs or other biologically active compounds, hydrogels sensitive to the most important stimuli in the human body, such as temperature, pH, ionic strength, glucose and biomolecules released by the organism in pathological conditions have been developed. Finally, to assist and validate the experimental studies, computer modelling and simulations of large-sized molecular structures and systems using different molecular dynamics and quantum mechanical techniques are developed based on the experimental and chemistry synthesis. This book is of great interest for graduate students, researchers and health professionals interested in acquiring a better understanding of the mechanisms of medical treatments. In addition, it provides numerous tools to develop better therapies for human diseases.
Supramolecules In Drug Discovery And Drug Delivery
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Author : Thomas Mavromoustakos
language : en
Publisher: Humana
Release Date : 2020-10-29
Supramolecules In Drug Discovery And Drug Delivery written by Thomas Mavromoustakos and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-29 with Science categories.
This detailed book aims to provide readers with critical information to accomplish the synthesis of nanosystems for the purpose of supramolecular entities complexing with drugs, targeted drug delivery system characterization, as well as the study of the physical-chemical interactions that govern the stability and properties of these systems. Beginning with a collection of chapters on drug delivery platforms such as cyclodextrins, micelles, liposomes, polymeric, nanotubes, and more, the volume continues with coverage of the study of nanotechnology systems using different biophysical techniques such as DSC, ITC, solid and liquid NMR spectroscopy, and electrochemistry. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Supramolecules in Drug Discovery and Drug Delivery: Methods and Protocols serves as an ideal guide for researchers working toward drug delivery mechanisms that can tailor their physical chemical properties and enhance their efficacy, while retaining their structures intact.
Supramolecular Design For Biological Applications
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Author : Nobuhiko Yui
language : en
Publisher: CRC Press
Release Date : 2002-03-11
Supramolecular Design For Biological Applications written by Nobuhiko Yui and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-03-11 with Medical categories.
Supramolecular chemistry is the outburst topic of the next generation of science. While the majority of biomedical research efforts to date have centered on utilizing well-known polymeric materials, the recent progress in supramolecular chemistry has introduced a fascinating new field of macromolecular architecture. Supramolecular Design fo
Applications Of Supramolecular Chemistry
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Author : Hans-Jorg Schneider
language : en
Publisher: CRC Press
Release Date : 2012-03-28
Applications Of Supramolecular Chemistry written by Hans-Jorg Schneider and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-28 with Medical categories.
Applications of Supramolecular Chemistry introduces the use of non-covalent interactions and molecular recognition for many fields. Applications include the analysis of technically, medically, and environmentally important chemical compounds, their separation, purification and removal, and the design of new materials, including supramolecular elect
Supramolecular Synthons In Crystal Engineering Of Pharmaceutical Properties
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Author : ASHWINI KUMAR. NANGIA
language : en
Publisher:
Release Date : 2024-10
Supramolecular Synthons In Crystal Engineering Of Pharmaceutical Properties written by ASHWINI KUMAR. NANGIA and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10 with Medical categories.
This comprehensive resource skillfully consolidates Crystal Engineering, the design of organic solids, and Supramolecular Synthons (i.e. structural hydrogen bond units) to achieve desired Pharmaceutical Properties, including solubility, dissolution, bioavailability, permeability, particle size, tableting, hydration, and mechanical strength. Covering 30 years of crystal engineering developments and pharmaceutical applications, this book will be a single and complete resource for supramolecular and structural chemists, the crystal engineering community, pharmaceutical scientists, and industrial researchers. Selling Points Covers the fundamentals of crystal engineering and supramolecular synthons. Details the challenges of low solubility and low permeability facing oral drug formulations. Explains how heterosynthons provide a rational approach to address and implement solutions. Provides case studies from academic and industrial labs to walk the reader through the actual steps. Explores developments in the scale up and manufacture of crystal forms in pharmaceutical industry.
Supramolecular Chemistry
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Author : Peter J. Cragg
language : en
Publisher: Springer
Release Date : 2014-09-25
Supramolecular Chemistry written by Peter J. Cragg and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-25 with Science categories.
The aim of this book is to return to the biomimicry and medicinal potential that inspired many of the early supramolecular chemists and to set it in the context of current advances in the field. Following an overview of supramolecular chemistry, the first section considers the efforts made to synthesize artificial systems that mimic biological entities. The second section addresses the application of supramolecular principles to molecular diagnostics with a particular emphasis on the ‘receptor-relayreporter’ motif. Many of the examples chosen have clinical importance. The third section takes the clinical diagnostic theme further and demonstrates the therapeutic applications of supramolecular chemistry through photodynamic therapy, drug delivery, and the potential for synthetic peptides to form antibiotic tubes. The short epilogue considers the potential for supramolecular solutions to be found for further challenges in biomimetic and therapeutic chemistry.
Bioconjugated Materials Part 2 Applications In Drug Delivery Vaccine Formulations And Important Conjugates For Cancer Therapy
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-11-03
Bioconjugated Materials Part 2 Applications In Drug Delivery Vaccine Formulations And Important Conjugates For Cancer Therapy written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-03 with Science categories.
Bioconjugated Materials Part 2, Volume 103 in the Comprehensive Analytical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on bioconjugated materials. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Comprehensive Analytical Chemistry series Updated release includes the latest information on Isotope Dilution