Pharmacological Assays Of Plant Based Natural Products
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Pharmacological Assays Of Plant Based Natural Products
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Author : Thangaraj Parimelazhagan
language : en
Publisher: Springer
Release Date : 2015-12-29
Pharmacological Assays Of Plant Based Natural Products written by Thangaraj Parimelazhagan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-29 with Medical categories.
This volume provides information on how to select and screen plants for their medicinal properties. It describes phytopharmacological techniques for extracting and qualitatively and quantitatively analyzing a plant’s phytochemicals. After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc. Compound identification and purification techniques include, among others, TLC and column chromatography, as well as molecular docking with specific proteins.
Plant Based Natural Products
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Author : Shahid Ul-Islam
language : en
Publisher: John Wiley & Sons
Release Date : 2017-07-18
Plant Based Natural Products written by Shahid Ul-Islam and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-18 with Science categories.
Intense research has been started all around the world in the past few decades to exploit different agents from natural products as eco-friendly alternative to synthetic and toxic chemicals. Natural products and their derivatives have received increasing attention for their use in many everyday applications ranging from food, medicine, textiles, and healthcare.This new book presents significant research advances about the use of natural products, mainly plant colorants, bioactive compounds and other plant extracts in the textile coloration, food, bioremediation and environmental applications. There are total eight chapters contributed by leading researchers covering the topics such as potential resurgence of natural dyes in applied fields, natural colorants from indigoid plants, phytochemistry of dye yielding plants, irradiation as novel pretreatment methods, dyeing studies with henna plant, phytoremediation of arsenic, and synthesis of curcumin complexes for medicinal and other industrial uses.
Pharmacological Properties Of Plant Derived Natural Products And Implications For Human Health
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Author : George E. Barreto
language : en
Publisher: Springer
Release Date : 2021-04-17
Pharmacological Properties Of Plant Derived Natural Products And Implications For Human Health written by George E. Barreto and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-17 with Medical categories.
Medicinal plants and their derived products remain as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery. There are several advantages for plant-derived therapeutics including wide availability, diverse pharmacological actions and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying to the efficacy and safety of medicinal plants and phytochemicals in ameliorating several human diseases. A plethora of basic studies has also unravelled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products and drug interactions remain to be further studied. In this book, we aim to put together several chapters on the medicinal properties and pharmacological action of medicinal plants, plant species and phytochemicals. The goal is to present a comprehensive collection on most of the therapeutic aspects of plant-derived natural products and molecular mechanisms thereof.
Plant Derived Natural Products
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Author : Anne E. Osbourn
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-07-07
Plant Derived Natural Products written by Anne E. Osbourn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-07 with Science categories.
Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.
Plant Extracts
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Author : Raffaele Capasso
language : en
Publisher: MDPI
Release Date : 2021-04-29
Plant Extracts written by Raffaele Capasso and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-29 with Medical categories.
Plant extracts are widely used for therapeutic purposes. The vegetal origin of these products satisfies people’s desire to cure themselves with natural drugs; this aspect, together with effectiveness and regulatory opportunities, is the base of the broad modern use of medicinal plants. Traditional uses and novel biological effects allow the availability of an extraordinarily high number of different compounds with formidable therapeutic potential. Nevertheless, pitfalls are hidden behind poor pharmacological and toxicological knowledge of plant extracts, nonstandardized methods of extraction, and undefined and nonrepeatable qualitative and quantitative composition. In this context, novel experimental studies on plant products and appreciated and are necessary to reinforce the scientific soundness of phytotherapy. This book aims to respond to this medical need comprehensively highlighting the newest discoveries in vegetal resources with an emphasis on pharmacological activity.
Chemistry Of Natural Products
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Author : Mayuri Napagoda
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2022-04-19
Chemistry Of Natural Products written by Mayuri Napagoda and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-19 with Science categories.
Plants produce secondary metabolites that humans harness for their own benefit. About half of drugs currently in clinical use are based on these chemicals found in nature. Chemistry of Natural Products covers secondary metabolites present in medicinal plants and their biosynthesis, biological activities, and isolation and separation techniques. This book is ideal for researchers in the areas of biochemistry, medicine, and pharmacology.
Plant Bioactives And Drug Discovery
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Author : Valdir Cechinel-Filho
language : en
Publisher: John Wiley & Sons
Release Date : 2012-05-22
Plant Bioactives And Drug Discovery written by Valdir Cechinel-Filho and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-22 with Science categories.
An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies today. With coverage of strategic methods of natural compound isolation, structural manipulation, natural products in clinical trials, quality control, and more, and featuring case studies on medicinal plants, the book serves as a definitive guide to the field of plant biodiversity as it relates to medicine. In addition, chapters on using natural products as drugs that target specific disease areas, including neurological disorders, inflammation, infectious diseases, and cancer, illustrate the myriad possibilities for therapeutic applications. Wide ranging and comprehensive, Plant Bioactives and Drug Discovery also includes important information on marketing, regulations, intellectual property rights, and academic-industry collaboration as they relate to plant-based drug research, making it an essential resource for advanced students and academic and industry professionals working in biochemical, pharmaceutical, and related fields.
Bioassay Methods In Natural Product Research And Drug Development
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Author : Lars Bohlin
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Bioassay Methods In Natural Product Research And Drug Development written by Lars Bohlin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Bioassay Methods in Natural Product Research and Drug Development contains the proceedings from the Phytochemical Society of Europe's very successful symposium on this topic, held August 24-27, 1997 in Uppsala, Sweden. In this volume, leading academic and industrial scientists discuss novel methods for assaying natural products to find new structure-activity relationships. Of key importance in this process is the availability and reliability of specific bioassay methods, but chapters also discuss chemical and biological diversity and how to dereplicate natural product extracts to increase efficiency in lead discovery. Anti-tumor, HIV-inhibitory, antiprotozoal, anti-infective and immunomodulatory natural products are discussed. Various industrial projects are presented for the first time. This volume bridges the gap between academic and industrial research and scientists, and should be required reading in drug companies and faculties of pharmacy, as well as serving scientists in pharmacognosy, pharmacology, phytochemistry, natural products and drug discovery.
Quality Control And Evaluation Of Herbal Drugs
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Author : Pulok K. Mukherjee
language : en
Publisher: Elsevier
Release Date : 2019-05-30
Quality Control And Evaluation Of Herbal Drugs written by Pulok K. Mukherjee and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-30 with Science categories.
Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs’ activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities
Modern Phytomedicine
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Author : Iqbal Ahmad
language : en
Publisher: John Wiley & Sons
Release Date : 2006-12-13
Modern Phytomedicine written by Iqbal Ahmad and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-13 with Medical categories.
This timely and original handbook paves the way to success in plant-based drug development, systematically addressing the issues facing a pharmaceutical scientist who wants to turn a plant compound into a safe and effective drug. Plant pharmacologists from around the world demonstrate the potentials and pitfalls involved, with many of the studies and experiments reported here published for the first time. The result is a valuable source of information unavailable elsewhere.