Pharmacotherapy Of Pulmonary Hypertension
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Pharmacotherapy Of Pulmonary Hypertension
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Author : Marc Humbert
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-04
Pharmacotherapy Of Pulmonary Hypertension written by Marc Humbert and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-04 with Medical categories.
This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area. The first part of the book covers the definition, classification, pathophysiology, pathology, biomarkers and animal models of the disease, thus laying the conceptual basis for what follows. The middle section provides an overview of the established therapies, such as calcium channel blockers, prostanoids, endothelin receptor antagonists, phosphodiesterase-5 inhibitors and inhaled nitric oxide. The last section explores novel pathways and emerging therapeutic approaches including soluble guanylate cyclase stimulators, Rho-kinase inhibitors, inhibitors of serotonin receptors and transporters, peptide growth factors, vasoactive peptides, modulators of redox equilibrium and cyclic nucleotide homeostasis, as well as immunosuppressive and anti-proliferative agents. Particular attention is given to the clinical applications of these experimental therapies, that are on the horizon. The book thus spans the continuum from basic science to clinical applications.
Pharmacotherapy Of Pulmonary Hypertension
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Author : Marc Humbert
language : en
Publisher:
Release Date : 2013-10-31
Pharmacotherapy Of Pulmonary Hypertension written by Marc Humbert and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-31 with categories.
Treatment Of Pulmonary Hypertension
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Author : Brendan Madden
language : en
Publisher: Springer
Release Date : 2015-08-10
Treatment Of Pulmonary Hypertension written by Brendan Madden and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-10 with Medical categories.
This title will be presented as highly practical information on pharmaceutical options in pulmonary hypertension, written in a quick-access, no-nonsense format. The emphasis will be on a just-the-facts clinical approach, heavy on tabular material, light on dense prose. The involvement of the ISCP will ensure that the best quality contributors will be involved and establish a consistent approach to each topic in the series. Each volume is designed to be between 100 and 150 pages containing practical illustrations and designed to improve understand and practical usage of cardiovascular drugs in specific clinical areas.
Diagnosis And Treatment Of Pulmonary Hypertension
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Author : Yoshihiro Fukumoto
language : en
Publisher: Springer
Release Date : 2017-01-05
Diagnosis And Treatment Of Pulmonary Hypertension written by Yoshihiro Fukumoto and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-05 with Medical categories.
This book focuses on pulmonary arterial hypertension (PAH, Group 1) and chronic thromboembolic pulmonary hypertension (CTEPH, Group 4) among the various groups of pulmonary hypertension (PH) whose classification was updated into five major categories at the 5th World Symposium held in Nice, France, in 2013. Readers will find recent progress, methods, and up-to-date information on PH mechanisms, diagnostic images, and treatment in the management of PH.This volume, with contributions by leading researchers worldwide in the field , consists of five parts, starting with the fundamentals of PH, then pathophysiology and genetics, treatment, and right ventricular function.
Pulmonary Arterial Hypertension
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Author : Robyn Barst
language : en
Publisher: John Wiley & Sons
Release Date : 2008-09-15
Pulmonary Arterial Hypertension written by Robyn Barst and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-15 with Medical categories.
First book dedicated to this disease, previously thought to be incurable, but with the advent of new drugs, now amenable to management and a much improved prognosis for patients From the PAH Association, the leading experts in field Incorporates the latest AACP management guidelines Includes evidence-based treatment algorithms based on the recently updated ACCP Guidelines for Medical Treatment Aimed at specialists in pulmonology and cardiovascular disease, this volume provides the clinician with the most up to date information on the effective management of PAH
Introduction To Basics Of Pharmacology And Toxicology
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Author : Abialbon Paul
language : en
Publisher: Springer Nature
Release Date : 2021-03-13
Introduction To Basics Of Pharmacology And Toxicology written by Abialbon Paul and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-13 with Medical categories.
This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.
Pulmonary Hypertension
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Author : Sics Editore
language : en
Publisher: SICS Editore
Release Date : 2014-10-01
Pulmonary Hypertension written by Sics Editore and has been published by SICS Editore this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-01 with Medical categories.
Pulmonary hypertension (PH) denotes a state where the mean pulmonary artery pressure is 25 mmHg or higher (measured invasively via right heart catheterisation in specialist medical care). In clinical practice, echocardiography is used as a screening tool because it provides the means to indirectly estimate the pressure within the pulmonary arteries. The most common causes of increased pulmonary blood pressure are problems related to the left side of the heart (such as ventricular failure and valvular defects) and hypoxaemia caused either by lung disease or other conditions (such as COPD, pulmonary fibrosis and sleep apnoea). In these situations the increase in pulmonary blood pressure is a secondary haemodynamic phenomenon and, according to current understanding, it only plays a minor role as far as the management of the condition is concerned. At present, no evidence exists on the benefit of PH medication in the treatment of these conditions. Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are markedly rarer causes of PH, and in these conditions both pulmonary blood pressure and pulmonary vascular resistance play a major role. The principal mechanism behind PAH is an endothelial dysfunction in the small pulmonary arteries leading to an imbalance between vasoactive mediators (e.g. prostacycline, nitrous oxide and endothelin), which are responsible for the dilatation and constriction of the vessels as well as for enhancing or inhibiting vascular proliferation. Promising new drugs have been introduced during the last few years for the treatment of PAH, which improve the patient’s functional capacity and probably also the prognosis. The investigations of PH are always carried out in specialist medical care, and the diagnosis and treatment of PAH and CTEPH should be concentrated in specialist centres.
Pulmonary Hypertension An Issue Of Clinics In Chest Medicine
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Author : Aaron B Waxman
language : en
Publisher: Elsevier Health Sciences
Release Date : 2021-02-05
Pulmonary Hypertension An Issue Of Clinics In Chest Medicine written by Aaron B Waxman and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-05 with Medical categories.
This issue of Clinics in Chest Medicine, guest-edited by Dr. Aaron B Waxman and Dr. Inderjit Singh, is focused on Pulmonary Hypertension. Topics discussed in this issue include but are not limited to: Integrative omics to characterize and classify pulmonary vascular disease, Contemporary Pharmacotherapeutic Approach in Pulmonary Arterial Hypertension, Personalized Medicine: The Future Management of Pulmonary Hypertension Requires A New Taxonomy, Sex differences in Pulmonary Hypertension and Pulmonary Hypertension in Pregnancy
Pulmonary Arterial Hypertension
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Author : Jochen Antel
language : en
Publisher: IOS Press
Release Date : 2010
Pulmonary Arterial Hypertension written by Jochen Antel and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
Pulmonary hypertension is a fatal lung and heart disease. It is characterized by shortness of breath, fatigue and fainting. It is exacerbated by an increase of the pressure in the lung vasculature through exercise, leading to progressive worsening of hemodynamics, right ventricular hypertrophy, right heart insufficiency and finally right heart failure. This book focuses on pulmonary arterial hypertension, a rare and progressive subgroup of pulmonary hypertension, which is today incurable and terminally faal. Classification of pulmonary arterial hypertension, its pathology, and strategies for future therapy will be of interest both to those suffering from the disease and those who take care of patients. This volume will also engage physicians and other scientists contributing to an understanding of the pathophysiology of pulmonary arterial hypertension and attempting to extend life of humans with pulmonary arterial hypertension by developing causal and curative therapies.
Pulmonary Hypertension
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Author : Bradley A. Maron
language : en
Publisher: Springer
Release Date : 2015-11-02
Pulmonary Hypertension written by Bradley A. Maron and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-02 with Medical categories.
This book provides the framework for a singular reference in the field of pulmonary hypertension. Pulmonary vascular disease is a complex and heterogeneous condition characterized by remodeling of distal pulmonary arterioles that increases pulmonary vascular resistance to affect cardiopulmonary hemodynamic and right ventricular function adversely, resulting in a clinical syndrome of diminished exercise tolerance, shortness of breath, and heart failure-associated morbidity and mortality. Owing to the availability of novel pulmonary circulation-selective pharmacotherapies over the previous decade, the number of pulmonary hypertension patients eligible for treatment has increased substantially. Despite this progress, under-awareness persists within the practicing pulmonary, cardiovascular, and general internal medicine communities. This is due, in part, to the complex array of molecular mechanisms implicated in the pathobiology of PH, as well as cutting-edge discoveries from translational scientific works that provide a new framework by which to understand pulmonary vascular-right ventricular coupling. Taken together, a key educational opportunity is exposed to bridge this knowledge gap through the synthesis of a contemporary text that emphasizes basic science, translational and clinical principles, and treatment strategies for understanding pulmonary hypertension.