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Physical Basis Of Cell Cell Adhesion

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Physical Basis Of Cell Cell Adhesion

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Author : Pierre Bongrand
language : en
Publisher: CRC Press
Release Date : 2018-02-01

Physical Basis Of Cell Cell Adhesion written by Pierre Bongrand and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-01 with Science categories.

The Present book is aimed at providing a readable account of physical methods and results required to measure cell adhesion and interpret experimental data. Since on the one hand readability seemed a major quality for a book, and on the other hand, the problems posed referred to a wide range of domains of physics, chemistry, and biology, completeness had to sacrificed. Indeed, a whole book would not suffice to quote the relevant literature (and many more authors would be required to have read it). Hence, only a limited number of topics were selected for reliability of methods, availability of enough experimental results to illustrate basic conception or potential use in the future. These were discussed in three sections.

Physical Basis Of Cell Cell Adhesion

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Author : Pierre Bongrand
language : en
Publisher: CRC Press
Release Date : 2018-02-01

Physics Of Bio Molecules And Cells

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Author : Henrik Flyvbjerg
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-07-01

Physics Of Bio Molecules And Cells written by Henrik Flyvbjerg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-01 with Science categories.

Aimed at those working to enter this rapidly developing field, this volume on biological physics is written in a pedagogical style by leading scientists giving explanations that take their starting point where any physicist can follow and end at the frontier of research in biological physics. These lectures describe the state-of-the-art physics of biomolecules and cells. In biological systems ranging from single biomolecules to entire cells and larger biological systems, it focuses on aspects that require concepts and methods from physics for their analysis and understanding, such as the mechanics of motor proteins; how the genetic code is physically read and managed; the machinery of protein--DNA interactions; force spectroscopy of biomolecules' velopes, cytoskeletons, and cytoplasms; polymerization forces; listeria propulsion; cell motility; lab-on-a-chip nanotechnology for single-molecule analysis of biomolecules; bioinformatics; and coding and computational strategies of the brain.

Studying Cell Adhesion

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Author : Pierre Bongrand
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17

Studying Cell Adhesion written by Pierre Bongrand and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.

Cell adhesion - the attachment of cells to any surface such as other cell membranes or tissues - is a complex process. In many physiological and pathological processes adhesion of a cell is the first critical step. A wide spectrum of the most powerful techniques currently available to study the basic parameters of cell adhesion, including binding strength, binding efficiency, membrane-membrane or membrane-substrate interaction, structural properties and dynamics of cell surface molecules, is presented in this strategy book. Sophisticated quantitative approaches as well as comprehensible semi-quantitative methods are described. The detailed theoretical background allows the critical assessment and application of these techniques.

Principles Of Cell Adhesion 1995

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Author : Peter D. Richardson
language : en
Publisher: CRC Press
Release Date : 2017-11-22

Principles Of Cell Adhesion 1995 written by Peter D. Richardson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-22 with Science categories.

Intended for cell biologists, biophysicists, biochemists, molecular biologists, physiologists, researchers in hemostatsis and thrombosis and pathologists, this book provides an insight into cell adhesion from three interdisciplinary perspectives: fundamental facts of adhesion; molecular biochemistry of adhesion and physiological aspects. It summarizes the basic aspects of surfaces in general and describes the theoretical and experimental tools necessary to investigate cell adhesion, including the basic biochemistry and molecular biology of adhesion. The book offers concise treatment of individual topics, features current material, and provides key references as a guide to further study.

Cell And Model Membrane Interactions

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Author : S. Ohki
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Cell And Model Membrane Interactions written by S. Ohki and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

Membrane interaction is a large research area involving various disciplines. A symposium entitled "Cell and Model Membrane Interactions" which took place in Boston, MA during the 155th American Chemical Society Meeting, April 25, 1990, focused on membrane adhesion and fusion. The topics were explored in studies involving lipids, virus envelopes and cell membranes. Especially discussed, were the roles of polymers, lipids, and proteins on these membrane interactions. Fusion of membrane is an important molecular event which plays a pivotal role in many dynamic cellular processes, such as exocytosis, endocytosis, membrane genesis, viral infection processes, etc. The process includes adhesion of the mem branes, fusion, and finally reorganization of the components of the two membranes. The basic notion shared during the symposium was that membrane hydro phobicity, especially local membrane hydrophobicity is one of the important factors contributing to membrane fusion. Most of the papers are collected here and they are arranged approximately in the same order as they were presented at the sympo sium. These papers are the most up-to-date and representative work at the forefront in each membrane interaction field. I sincerely hope the reader will gain further understanding on membrane interactions especially, membrane and vesicle fusion phenomena through this symposium proceedings volume.

Molecular Adhesion And Its Applications

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Author : Kevin Kendall
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-08

Molecular Adhesion And Its Applications written by Kevin Kendall and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-08 with Science categories.

At the beginning of the twentieth century, engineers and technologists would have recognized the importance of adhesion in two main aspects: First, in the display of friction between surfaces — at the time a topic of growing importance to engineers; the second in crafts requiring the joining of materials — principally wood—to form engineering structures. While physical scientists would have admitted the adhesive properties of glues, gels, and certain pastes, they regarded them as materials of uncertain formulation, too impure to be amenable to precise experiment. Biological scientists were aware also of adhesive phenomena, but the science was supported by documentation rather than understanding. By the end of the century, adhesion and adhesives were playing a crucial and deliberate role in the formulation of materials, in the design and manufacture of engineering structures without weakening rivets or pins, and in the use of thin sections and intricate shapes. Miniaturization down to the micro- and now to the nano-level of mechanical, electrical, electronic, and optical devices relied heavily on the understanding and the technology of adhesion. For most of the century, physical scientists were aware that the states of matter, whether gas, liquid, or solid, were determined by the competition between thermal energy and int- molecular binding forces. Then the solid state had to be differentiated into crystals, amorphous glasses, metals, etc. , so the importance of the molecular attractions in determining stiffness and strength became clearer.

Smart Materials For Drug Delivery

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Author : Carmen Alvarez-Lorenzo
language : en
Publisher: Royal Society of Chemistry
Release Date : 2013-04-25

Smart Materials For Drug Delivery written by Carmen Alvarez-Lorenzo and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-25 with Technology & Engineering categories.

Smart materials, which can change properties when an external stimulus is applied, can be used for the targeted drug delivery of an active molecule to a specific site in the correct dosage. Different materials such as liposomes, polymeric systems, nanomaterials and hydrogels can respond to different stimuli such as pH, temperature and light and these are all attractive for controlled release applications. With so many papers available on smart and stimuli-responsive materials for drug delivery applications it's hard to know where to start reading about this exciting topic. This two volume set brings together the recent findings in the area and provides a critical analysis of the different materials available and how they can be applied to advanced drug delivery systems. With contributions from leading experts in the field, including a foreword from distinguished scientist Nicholas Peppas, The University of Texas at Austin, USA, the book will provide both an introduction to the key areas for graduate students and new researchers in the stimuli-responsive field as well as serving as a reference for those already working on fundamental materials research or drug delivery applications.

Computational Pharmaceutics

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Author : Defang Ouyang
language : en
Publisher: John Wiley & Sons
Release Date : 2015-05-19

Computational Pharmaceutics written by Defang Ouyang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-19 with Science categories.

Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening. Now these techniques are used to model or mimic the behavior of molecules, and help us study formulation at the molecular level. Computational pharmaceutics enables us to understand the mechanism of drug delivery, and to develop new drug delivery systems. The book discusses the modeling of different drug delivery systems, including cyclodextrins, solid dispersions, polymorphism prediction, dendrimer-based delivery systems, surfactant-based micelle, polymeric drug delivery systems, liposome, protein/peptide formulations, non-viral gene delivery systems, drug-protein binding, silica nanoparticles, carbon nanotube-based drug delivery systems, diamond nanoparticles and layered double hydroxides (LDHs) drug delivery systems. Although there are a number of existing books about rational drug design with molecular modeling techniques, these techniques still look mysterious and daunting for pharmaceutical scientists. This book fills the gap between pharmaceutics and molecular modeling, and presents a systematic and overall introduction to computational pharmaceutics. It covers all introductory, advanced and specialist levels. It provides a totally different perspective to pharmaceutical scientists, and will greatly facilitate the development of pharmaceutics. It also helps computational chemists to look for the important questions in the drug delivery field. This book is included in the Advances in Pharmaceutical Technology book series.

Membrane Biogenesis

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Author : Jos A.F. Op den Kamp
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Membrane Biogenesis written by Jos A.F. Op den Kamp and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.

Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.

Physical Basis Of Cell Cell Adhesion

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