Physical Properties Of Biological Membranes And Their Functional Implications
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Physical Properties Of Biological Membranes And Their Functional Implications
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Author : Cecilia Hidalgo
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Physical Properties Of Biological Membranes And Their Functional Implications written by Cecilia Hidalgo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This book was originated from a series of lectures given in a course on the physical properties of biological membranes and their functional implica tions. The course was intended to allow students to get acquainted with the physical techniques used to study biological membranes. The experience was valuable and we feel that a detailed description of the procedures used and of various examples of the results obtained allowed many students to become familiar with a theme that is not often part of regular courses on membrane physiology or biophysics. This book is designed as a tutorial guide for graduate students interested in understanding how physical methods can be utilized to study the proper ties of biological membranes. It includes first a detailed description of applications of physical techniques-such as X-ray fiber diffraction methods (Chapter 1), 2H and 13C NMR spectroscopy (Chapter 2), and calorimetry (Chapter 3)-in the study of the properties of lipid model membranes. A description of how to measure molecular mobility in membranes (Chapter 4) follows, and the book concludes with three chapters in which biological membranes are the subject of study. Chapter 5 deals with the acetylcholine receptor and its membrane environment; Chapter 6 discusses how fluorescence techniques can be applied in the study of the calcium ATPase of sarcoplasmic reticulum; and Chapter 7 explains how protein lipid interactions modulate the function of the sodium and proton pumps.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Membrane Hydration
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Author : E. Anibal Disalvo
language : en
Publisher: Springer
Release Date : 2015-10-05
Membrane Hydration written by E. Anibal Disalvo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-05 with Science categories.
This book is about the importance of water in determining the structure, stability and responsive behavior of biological membranes. Water confers to lipid membranes unique features in terms of surface and mechanical properties. The analysis of the hydration forces, plasticiser effects, controlled hydration, formation of microdomains of confined water suggests that water is an active constituent in a water-lipid system. The chapters describe water organization at the lipid membrane–water interphase, the water penetration, the long range water structure in the presence of lipid membranes by means of X-ray and neutron scattering, general polarization, fluorescent probes, ATR-FTIR and near infrared spectroscopies, piezo electric methods, computer simulation and surface thermodynamics. Permeation, percolation, osmotic stress, polarization, protrusion, sorption, hydrophobicity, density fluctuations are treated in detail in self-assembled bilayers. Studies in lipid monolayers show the correlation of surface pressure with water activity and its role in peptide and enzyme interactions. The book concludes with a discussion on anhydrobiosis and the effect of water replacement in microdomains and its consequence for cell function. New definitions of lipid/water interphases consider water not only as a structural-making solvent but as a mediator in signalling metabolic activity, modulating protein insertion and enzymatic activity, triggering oscillatory reactions and functioning of membrane bound receptors. Since these effects occur at the molecular level, membrane hydration appears fundamental to understand the behavior of nano systems and confined environments mimicking biological systems. These insights in structural, thermodynamical and mechanical water properties give a base for new paradigms in membrane structure and function for those interested in biophysics, physical chemistry, biology, bio and nano medicine, biochemistry, biotechnology and nano sciences searching for biotechnological inputs in human health, food industry, plant growing and energy conversion.
The Physical Chemistry Of Membranes
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Author : B. Silver
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Physical Chemistry Of Membranes written by B. Silver and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Ls book is an account of what physical chemistry h . . to say about the structural, electrical and transport properties of biological membranes and their simplest model-the lipid bilayer. The accent throughout is on basic ideas. In contrast to the essentially descriptive ap proach characteristic of texts on membrane biochemistry, our underlying themes are the role of force and entropy in maintaining membrane organization, in determining the electric fields and ionic environment of membranes, and in regulating the passage of molecules and ions across membranes. Although experimental findings will always be the touch stone against which theory will be tried, no attempt is made to present an exhaustive survey of experimental data. On the other hand, there is discussion of the nature and limitations of the results obtainable by the major laboratory techniques. The treatment is at the level of an advanced undergraduate course or an introductory survey suitable for post graduate students carrying out research in biochemistry, biophysics, or physiology. The mathematical demands on the reader are trivial. The few forbidding equations appearing in Chapter 7 are soon whittled away to simple practical expressions. Although the current-voltage characteristics of nerves are traditionally the province of biophysics rather than physical chemistry, certain aspects relevant to the electrical activity of nerves are nevertheless included in this text, namely, mem brane and diffusion potentials and conductivity fluctuations. Where rival theories exist, conflicting convictions have been presented, but not necessarily accorded equal approbation. The author has a viewpoint.
The Biophysics Of Cell Membranes
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Author : Richard M. Epand
language : en
Publisher: Springer
Release Date : 2017-09-25
The Biophysics Of Cell Membranes written by Richard M. Epand and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-25 with Science categories.
This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase separation) that are relevant to the functioning of biological membranes. The first chapter describes innovative methods to mimic the prevailing asymmetry in biological membranes by forming asymmetrical membranes made of monolayers with different compositions. One of the chapters illustrates how physical parameters, like curvature and elasticity, can affect and modulate the interactions between lipids and proteins. This volume also describes the sensitivity of certain ion channels to mechanical forces and it presents an analysis of how cell shape is determined by both the cytoskeleton and the lipid domains in the membrane. The last chapter provides evidence that liposomes can be used as a minimal cellular model to reconstitute processes related to the origin of life. Each topic covered in this volume is presented by leading experts in the field who are able to present clear, authoritative and up-to-date reviews. The novelty of the methods proposed and their potential for a deeper molecular description of membrane functioning are particularly relevant experts in the areas of biochemistry, biophysics and cell biology, while also presenting clear and thorough introductions, making the material suitable for students in these fields as well.
Molecular Specialization And Symmetry In Membrane Function
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Author : Arthur Kaskel Solomon
language : en
Publisher: Harvard University Press
Release Date : 1978
Molecular Specialization And Symmetry In Membrane Function written by Arthur Kaskel Solomon and has been published by Harvard University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Science categories.
Biological membranes have been under intensive investigation for several decades. Despite very great experimental challenges, membranes are at last beginning to reveal their secrets. In this book, leading investigators of membrane structure and function report on progress in three related fields: specialization of membrane regions, asymmetry in transport properties, and differentiation of cell faces in epithelia. "Specialization at the Molecular Level" is the subject of the first section; in it, the authors consider such problems as the biogenesis of membranes, the geometry of protein-lipid relationships, and the physical properties of membrane receptor-sites. In the second section, "Asymmetry in Transport," such topics as the sodium-potassium pump, proton translocation, and anion transport are covered. The last section is entitled "Polar Faces in Epithelia" and deals with the complex properties of ion transport across the complex membrane environment maintained by surfaces such as the renal tubular epithelia.
Biological Membranes
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Author : Dennis Chapman
language : en
Publisher:
Release Date : 1968
Biological Membranes written by Dennis Chapman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1968 with Cell membranes categories.
Thermal Biophysics Of Membranes
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Author : Thomas Heimburg
language : en
Publisher: John Wiley & Sons
Release Date : 2008-02-08
Thermal Biophysics Of Membranes written by Thomas Heimburg and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-08 with Science categories.
An overview of recent experimental and theoretical developments in the field of the physics of membranes, including new insights from the past decade. The author uses classical thermal physics and physical chemistry to explain our current understanding of the membrane. He looks at domain and 'raft' formation, and discusses it in the context of thermal fluctuations that express themselves in heat capacity and elastic constants. Further topics are lipid-protein interactions, protein binding, and the effect of sterols and anesthetics. Many seemingly unrelated properties of membranes are shown to be intimately intertwined, leading for instance to a coupling between membrane state, domain formation and vesicular shape. This also applies to non-equilibrium phenomena like the propagation of density pulses during nerve activity. Also included is a discussion of the application of computer simulations on membranes. For both students and researchers of biophysics, biochemistry, physical chemistry, and soft matter physics.
Concepts Of Membrane Structure
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Author : Ronald Aloia
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Concepts Of Membrane Structure written by Ronald Aloia and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Technology & Engineering categories.
Membrane Fluidity in Biology, Volume 1: Concepts of Membrane Structure covers membrane properties influenced by alterations in membrane lipid compositions and/or other organizational parameters that are encompassed by the term fluidity. This book is composed of eight chapters that discuss significance of fluidity changes in both normal and pathological cellular functions. This book starts by describing membrane structural organization and composition and arrangement of the molecular components of cell membranes. This is followed by discussions on structural properties of lipids and role of nonbilayer lipid structures in membrane fusion. The methodological approaches in study of cellular membrane structural diversity and fluid mosaic model for accurate representation of membrane fluidity are also discussed. This volume then describes the phenomenon of reversed or ""negative"" membrane images, as viewed with transmission electron microscope. Chapters 6 and 7 explain the interaction of cytochrome P-450 with phospholipids and proteins in the endoplasmic reticulum and steps in the derivation of membrane structure and packing principles. Finally, the concluding chapter focuses on the membrane of the human red blood cell and presents relatively simple arguments concerning its physical properties. The book will serve as a primary source for research scientists and teachers interested in cellular membrane fluidity phenomena.
The Structure Of Biological Membranes
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Author : Philip L. Yeagle
language : en
Publisher: CRC Press
Release Date : 2011-07-18
The Structure Of Biological Membranes written by Philip L. Yeagle and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-18 with Medical categories.
Biological membranes provide the fundamental structure of cells and viruses. Because much of what happens in a cell or in a virus occurs on, in, or across biological membranes, the study of membranes has rapidly permeated the fields of biology, pharmaceutical chemistry, and materials science. The Structure of Biological Membranes, Third Edition pro