Physico Chemical Control Of Cell Function
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Physico Chemical Control Of Cell Function
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Author : Cesare Gargioli
language : en
Publisher: Frontiers Media SA
Release Date : 2019-10-17
Physico Chemical Control Of Cell Function written by Cesare Gargioli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-17 with categories.
Extracellular Matrix (ECM) has been considered for a long time merely a scaffold sustaining cell and tissue function. Despite this simplistic view shared by many, nowadays ECM and their mechanic-physical and chemical characteristic acquired a progressive larger role actively regulating cell life: survival, proliferation, gene expression and differentiation. The interplay between cells and the ECM is continuously controlled at the cell level in a dynamic way. While cells synthesize the raw components of the ECM, this in turn impacts on cell function by providing chemical, topographical and mechanical hints. Such stimuli have been proven to control several aspects of cell function, including survival, proliferation, differentiation and migration. The molecular pathways activated by cells in response to the physical cues arising from the ECM are being disclosed and thus the possibility to control cell function through materials design is becoming more realistic. Current in vitro protocols, relying in 2D cell culture system, entail reductionist approaches to the complexity of cell-ECM interaction and result in cells rapidly losing their distinctive functions in culture. Understanding and replicating the 3D microenvironmental cues affecting cell function appears as a mandatory requirement for the development of next-generation biomaterials, as well as for the establishment of more physiologically relevant and predictive in vitro models of diseases. Such an effort will require a multidisciplinary approach at the convergence of biophysics, biology, nanotechnology, and bioengineering.
Cell Instructive Materials To Control And Guide Cell Function
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Author : Paolo Netti
language : en
Publisher: Woodhead Publishing
Release Date : 2020-11-25
Cell Instructive Materials To Control And Guide Cell Function written by Paolo Netti and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-25 with Technology & Engineering categories.
Cell Instructive Materials to Control and Guide Cell Function: Programmable Bioactive Interfaces looks at the key determinants of the dynamic interface between cell and materials and how this can be applied in developing new, bioactive biomaterials surfaces. The interface between cell and synthetic materials has attracted considerable scientific and technological interest, leading to the awareness that functional interfaces can actively guide and control specific adhesion and recognitions events. - Introduces readers to the fundamentals of complex cell-material interface dynamics - Provides valuable tools for the control of the interfacial dynamics to instruct and control cells or tissues functions - Covers the prospect of encoding specific cell instructions on, or within, a biomaterial by micro- and nano-patterning materials features
Research Awards Index
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Author :
language : en
Publisher:
Release Date : 1989
Research Awards Index written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medicine categories.
Subject Index Of Current Research Grants And Contracts Administered By The National Heart Lung And Blood Institute
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Author : National Heart, Lung, and Blood Institute
language : en
Publisher:
Release Date : 1979
Subject Index Of Current Research Grants And Contracts Administered By The National Heart Lung And Blood Institute written by National Heart, Lung, and Blood Institute and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Cardiovascular system categories.
Comprehensive Biomaterials Ii
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Author : Kevin Healy
language : en
Publisher: Elsevier
Release Date : 2017-05-18
Comprehensive Biomaterials Ii written by Kevin Healy and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-18 with Technology & Engineering categories.
Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications
Research Grants Index
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Author : National Institutes of Health (U.S.). Division of Research Grants
language : en
Publisher:
Release Date : 1975
Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Medicine categories.
Toxicology Research Projects Directory
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Author :
language : en
Publisher:
Release Date : 1976-03
Toxicology Research Projects Directory written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976-03 with Toxicology categories.
An indexed directory of current research project abstracts in toxicology and related fields.
Subject Index Of Extramural Research Administered By The National Cancer Institute
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Author :
language : en
Publisher:
Release Date : 1978
Subject Index Of Extramural Research Administered By The National Cancer Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Cancer categories.
Current information about research grants and contracts supported by the National Cancer Institute. Subject listing gives contract or grant number and topic. Investigator, grant number, and contract number indexes.
Calcium And Cell Function
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Author : Wai Yiu Cheung
language : en
Publisher: Academic Press
Release Date : 2013-10-22
Calcium And Cell Function written by Wai Yiu Cheung and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
Calcium and Cell Function, Volume V emphasizes the roles of calcium in cellular functions. This book consists of eight chapters. Chapter 1 presents evidence for the role of calmodulin in cell proliferation. The role of calcium in the control of cyclic AMP metabolism in glial and pituitary tumor cells is analyzed in Chapter 2. Chapter 3 explains the evidence that calmodulin regulates neurotransmitter synthesis, while Chapter 4 deliberates the role of calcium in adipocytes. Chapter 5 is devoted to the modulatory function of lipomodulin in cellular phospholipid metabolism. The pharmacological properties of naphthalenesulfonamides as calmodulin antagonists, phophorylase kinase, and phospholipidsensitive calcium-dependent protein kinase are reviewed in the last chapters. This volume is valuable to biologists and medical practitioners interested in calcium and cell function.
Biomedical Composites
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Author : Luigi Ambrosio
language : en
Publisher: Elsevier
Release Date : 2009-11-23
Biomedical Composites written by Luigi Ambrosio and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-23 with Technology & Engineering categories.
Biocomposites are widely used in the medical industry to repair and restore bone, tooth, cartilage skin and other tissues. Biomedical composites, provides a thorough review of the current status, recent progress and future trends in composites for biomedical applications.Part one discusses the fundamentals of biocomposites with chapters on natural composites, design and fabrication of biocomposites, and hard and soft tissue applications of biocomposites. Part two then reviews applications of biocomposites. Chapters discuss composites for bone repair, composite coatings for implants, composites for spinal implants, injectable composites and composites for tissue engineered scaffolds. Chapters in part three discuss the biocompatibility, mechanical behaviour and failure of biocomposites with such topics as cellular response, testing of biocomposites and tribology of biocomposites. Finally part four reviews the future for biocomposites with chapters on nano-structured biocomposites, developing biocomposites as scaffolds and biocomposites in tissue engineering and regenerative medicine.With its distinguished editor and team of international contributors, Biomedical composites is an essential reference to materials scientists and researchers in industry and academia, as well as all those concerned with this increasingly important field. - Provides a thorough review of the current status, recent progress and future trends in composites for biomedical applications - Discusses the fundamentals of biocomposites with chapters on natural composites, design and fabrication of biocomposites and their applications - Chapters address composites for bone repair, spinal implants and various other applications and discuss biocompatability, mechanical behaviour and failure of biocomposites