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Physiological Control Of The Developing Gastrointestinal Circulation


Physiological Control Of The Developing Gastrointestinal Circulation
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Physiological Control Of The Developing Gastrointestinal Circulation


Physiological Control Of The Developing Gastrointestinal Circulation
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Author : Wei Qi Fan
language : en
Publisher:
Release Date : 1997

Physiological Control Of The Developing Gastrointestinal Circulation written by Wei Qi Fan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Enterocolitis, Neonatal necrotizing categories.




The Gastrointestinal Circulation


The Gastrointestinal Circulation
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Author : Peter Kvietys
language : en
Publisher: Biota Publishing
Release Date : 2009-12-01

The Gastrointestinal Circulation written by Peter Kvietys and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-01 with Science categories.


The microcirculation of the gastrointestinal tract is under the control of both myogenic and metabolic regulatory systems. The myogenic mechanism contributes to basal vascular tone and the regulation of transmural pressure, while the metabolic mechanism is responsible for maintaining an appropriate balance between O2 demand and O2 delivery. In the postprandial state, hydrolytic products of food digestion elicit a hyperemia, which serves to meet the increased O2 demand of nutrient assimilation. Metabolically linked factors (e.g., tissue pO2, adenosine) are primarily responsible for this functional hyperemia. The fenestrated capillaries of the gastrointestinal mucosa are relatively permeable to small hydrolytic products of food digestion (e.g., glucose), yet restrict the transcapillary movement of larger molecules (e.g., albumin). This allows for the absorption of hydrolytic products of food digestion without compromising the oncotic pressure gradient governing transcapillary fluid movement and edema formation. The gastrointestinal microcirculation is also an important component of the mucosal defense system whose function is to prevent (and rapidly repair) inadvertent epithelial injury by potentially noxious constituents of chyme. Two pathological conditions in which the gastrointestinal circulation plays an important role are ischemia/reperfusion and chronic portal hypertension. Ischemia/reperfusion results in mucosal edema and disruption of the epithelium due, in part, to an inflammatory response (e.g., increase in capillary permeability to macromolecules and neutrophil infiltration). Chronic portal hypertension results in an increase in gastrointestinal blood flow due to an imbalance in vasodilator and vasoconstrictor influences on the microcirculation. Table of Contents: Introduction / Anatomy / Regulation of Vascular Tone and Oxygenation / Extrinsic Vasoregulation: Neural and Humoral / Postprandial Hyperemia / Transcapillary Solute Exchange / Transcapillary Fluid Exchange / Interaction of Capillary and Interstitial Forces / Gastrointestinal Circulation and Mucosal Defense / Gastrointestinal Circulation and Mucosal Pathology I: Ischemia/Reperfusion / Gastrointestinal Circulation and Mucosal Pathology II: Chronic Portal Hypertension / Summary and Conclusions / References / Author Biography



Handbook Of Physiology


Handbook Of Physiology
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Author : Stanley G. Schultz
language : en
Publisher: Oxford University Press, USA
Release Date : 1989-08

Handbook Of Physiology written by Stanley G. Schultz and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-08 with categories.


Since the publication of the first volume on gastrointestinal motility in the Handbook of Physiology (1968), there has been an impressive development of new information, new methods and new understanding of motility. These advances span all levels of organization from single smooth muscle cells and neurons to integrated organ function, and they are expertly documented by the authors of this edition. Parallel progress in understanding the vascular system and lymphatics of the alimentary canal over the past 20 years is reviewed in equal detail. Among the topics given authoritative coverage are the ultrastructure of gastrointestinal smooth muscle, the extracellular matrix, and the mechanical properties of the musculature; electrical and chemical behavior of gut neurons and the immunocytochemical localization of neurotransmitters; the unique pattern of motility in the interdigestive state; measurement of intraluminal pressures and electrical and contractile activity at all levels of the gastrointestinal tract; abnormalities associated with parasitic infections; enterotoxins, emesis and surgical perturbations that shed light on normal mechanisms; the basic structure and ultrastructure of the gut vasculature; regional hemodynamics and regulation of the digestive circulation; and neuromuscular transmission in the gut musculature and its neurohormonal control. Overall, the book provides an unparalleled view of gastrointestinal motor and circulatory function. It will be of great use to a wide spectrum of readers, including physiologists, gastroenterologists, graduate students, and postdoctoral fellows



Geriatric Gastroenterology


Geriatric Gastroenterology
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Author : C. S. Pitchumoni
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-07-26

Geriatric Gastroenterology written by C. S. Pitchumoni and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-26 with Medical categories.


As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.



Anatomy And Physiology


Anatomy And Physiology
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Author : J. Gordon Betts
language : en
Publisher:
Release Date : 2013-04-25

Anatomy And Physiology written by J. Gordon Betts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-25 with categories.




Regulation Of Tissue Oxygenation Second Edition


Regulation Of Tissue Oxygenation Second Edition
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Author : Roland N. Pittman
language : en
Publisher: Biota Publishing
Release Date : 2016-08-18

Regulation Of Tissue Oxygenation Second Edition written by Roland N. Pittman and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-18 with Medical categories.


This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.



Oxford Textbook Of Critical Care


Oxford Textbook Of Critical Care
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Author : Webb
language : en
Publisher: Oxford University Press
Release Date : 2020-01-10

Oxford Textbook Of Critical Care written by Webb and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-10 with Medical categories.


Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.



Neural Control Of Gastrointestinal Function


Neural Control Of Gastrointestinal Function
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Author : David Grundy
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2011-12

Neural Control Of Gastrointestinal Function written by David Grundy and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12 with Science categories.


The gastrointestinal tract is a long, muscular tube responsible for the digestion of food, assimilation of nutrients and elimination of waste. This is achieved by secretion of digestive enzymes and absorption from the intestinal lumen, with different regions playing specific roles in the processing of specific nutrients. These regions come into play sequentially as ingested material is moved along the length of the GI tract by contractions of the muscle layers. In some regions like the oesophagus transit it rapid and measured in seconds while in others like the colon transit is measured in hours and even days, commensurate with the relative slow fermentation that takes place in the large bowel. An hierarchy of controls, neural and endocrine, serve to regulate the various cellular targets that exist in the gut wall. These include muscle cells for contraction and epithelial cells for secretion and absorption. However, there are complex interactions between these digestive mechanisms and other mechanisms that regulate blood flow, immune function, endocrine secretion and food intake. These ensure a fine balance between the ostensibly conflicting tasks of digestion and absorption and protection from potentially harmful ingested materials. They match assimilation of nutrients with hunger and satiety and they ensure that regions of the GI tract that are meters apart work together in a coordinated fashion to match these diverse functions to the digestive needs of the individual. This ebook will provide an overview of the neural mechanisms that control gastrointestinal function. Table of Contents: Neural Control of Gastrointestinal Function / Cells and Tissues / Enteric Nervous System / From Gut to CNS: Extrinsic Sensory Innervation / Sympathetic Innervation of the Gut / Parasympathetic Innervation of the Gut / Integration of Function / References



The Enteric Nervous System


The Enteric Nervous System
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Author : John Barton Furness
language : en
Publisher:
Release Date : 1987

The Enteric Nervous System written by John Barton Furness and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.




Cardiovascular Physiology E Book


Cardiovascular Physiology E Book
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Author : Achilles J. Pappano
language : en
Publisher: Elsevier Health Sciences
Release Date : 2012-12-20

Cardiovascular Physiology E Book written by Achilles J. Pappano and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-20 with Medical categories.


Cardiovascular Physiology gives you a solid understanding of how the cardiovascular system functions in both health and disease. Ideal for your systems-based curriculum, this title in the Mosby Physiology Monograph Series explains how the latest concepts apply to real-life clinical situations. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Get clear, accurate, and up-to-the-minute coverage of the physiology of the cardiovascular system. Master the material easily with objectives at the start of each chapter; self-study questions, summaries, and key words and concepts. Grasp the latest concepts in vascular, molecular, and cellular biology as they apply to cardiovascular function, thanks to molecular commentaries in each chapter. Apply information to clinical situations with the aid of clinical commentaries and highlighted clinical vignettes throughout.