Phytochemicals Signal Transduction And Neurological Disorders
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Phytochemicals Signal Transduction And Neurological Disorders
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Author : Akhlaq A. Farooqui
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-07-10
Phytochemicals Signal Transduction And Neurological Disorders written by Akhlaq A. Farooqui and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-10 with Medical categories.
Phytochemicals Signal Transduction and Neurological Disorders Phytochemicals are heterogeneous group of bioactive compounds produced by plants, which are extensively researched by scientists for their health-promoting potentials in human diseases. Unlike vitamins and minerals, phytochemicals are not required for sustaining cell viability, but they play an important role in protecting tissues and cells from the harmful effects of oxidative stress and inflammation. Examples of phytochemicals include catechins, resveratrol, ginkgo biloba, curcumin, and sulfur compounds found in garlic. Although, the precise molecular mechanisms associated with beneficial effects of phytochemicals still remain the subject of intense investigations, but it is becoming increasingly evident that phytochemicals mediate their effects by counteracting, reducing, and repairing the damage caused by oxidative stress and neuroinflammation. In addition, phytochemicals also stimulate the synthesis of adaptive enzymes and proteins through the stimulation of a transcription factor called Nrf2 and induction of phase II detoxifying enzymes. Consumption of phytochemicals induces neurohormetic response that results in the expression of adaptive stress-resistance genes that are responsible for encoding antioxidant enzymes, protein chaperones, and neurotrophic factor (BDNF). Based on the stimulation of signal transduction network and adaptive stress-resistance genes, it is proposed that the use of phytochemicals from childhood to old age along with regular exercise is an important strategy for maintaining normal aging and delaying onset of age-related neurological disorders (stroke, Alzheimer disease, and Parkinson disease). Phytochemicals Signal Transduction and Neurological Disorders presents readers with cutting edge and comprehensive information not only on bioavailability, and mechanism of action of phytochemicals in the brain, but also provides the molecular mechanism associated with beneficial effects of phytochemicals in neurotraumatic (stroke, spinal cord trauma, and traumatic brain injury) and neurodegenerative (Alzheimers disease, Parkinson disease, Huntington disease, and amyotrophic lateral sclerosis) diseases.
Neuroprotective Effects Of Phytochemicals In Neurological Disorders
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Author : Tahira Farooqui
language : en
Publisher: John Wiley & Sons
Release Date : 2017-02-02
Neuroprotective Effects Of Phytochemicals In Neurological Disorders written by Tahira Farooqui and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-02 with Medical categories.
Phytochemicals are naturally occurring bioactive compounds found in edible fruits, plants, vegetables, and herbs. Unlike vitamins and minerals, phytochemicals are not needed for the maintenance of cell viability, but they play a vital role in protecting neural cells from inflammation and oxidative stress associated with normal aging and acute and chronic age-related brain diseases. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the advances in our understanding of the potential neuroprotective benefits that these naturally occurring chemicals contain. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the role that a number of plant-based chemical compounds play in a wide variety of neurological disorders. Chapters explore the impact of phytochemicals on neurotraumatic disorders, such as stroke and spinal cord injury, alongside neurodegenerative diseases such as Alzheimer's and Parkinson's Disease, as well as neuropsychiatric disorders such as depression and schizophrenia. The chapters and sections of this book provide the reader with a big picture view of this field of research. Neuroprotective Effects of Phytochemicals in Neurological Disorders aims to present readers with a comprehensive and cutting edge look at the effects of phytochemicals on the brain and neurological disorders in a manner useful to researchers, neuroscientists, clinical nutritionists, and physicians.
Neuroprotective Effects Of Phytochemicals In Brain Ageing
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Author : Surajit Pathak
language : en
Publisher: Springer Nature
Release Date : 2024-06-05
Neuroprotective Effects Of Phytochemicals In Brain Ageing written by Surajit Pathak and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-05 with Science categories.
This book discusses the mechanism and therapeutic strategies of phytochemicals against brain ageing. It discusses the underlying anti-oxidative and anti-inflammatory mechanisms of the phytochemicals and the implications of these compounds in the prevention and treatment of geriatric diseases. It discusses the potential role of the highly complex interactive network between the gut and the brain in neurodegenerative diseases such as Parkinson’s disease (PD), and Alzheimer’s disease. The chapters provide insight into the mechanisms involved in brain ageing and the mechanism of actions of the phytochemicals that might be crucial in developing effective new therapies against brain ageing. The chapter also presents the mechanisms of action of phytoconstituents, bioavailabilities, and their effects on neuroinflammation. The chapters also examine the phytochemicals protection of neurons via targeting oxidative stress, mitochondrial dysfunction, neurotrophic factor deficit, apoptosis, and abnormal protein accumulation. This book aims to provide comprehensive and cutting-edge information on the potential neuroprotective role of phytochemicals on the brain and neurological disorders to researchers, neuroscientists, clinical nutritionists, and physicians.
Inflammation And Oxidative Stress In Neurological Disorders
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Author : Akhlaq A. Farooqui
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-01-27
Inflammation And Oxidative Stress In Neurological Disorders written by Akhlaq A. Farooqui and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-27 with Medical categories.
Unless new discoveries are made in the prevention or treatment of stroke, Alzheimer's Disease and depression, the number of patients with these diseases is sure to increase dramatically by the year 2050. Thus, developing strategies to retard or delay the onset of stroke, AD and depression these neurological disorders is of critical important. The present monograph will provide current and comprehensive information on the relationship between neuroinflammation and oxidative stress in age-related neurological disorders at the molecular level. The information described in this monograph on lifestyle (diet and exercise), genes and age is intended to facilitate and promote new discoveries for the treatment of age-related neurological disorders.
Phytonutrients And Neurological Disorders
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Author : Haroon Khan
language : en
Publisher: Academic Press
Release Date : 2023-07-11
Phytonutrients And Neurological Disorders written by Haroon Khan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-11 with Medical categories.
Phytonutrients and Neurological Disorders: Therapeutic and Toxicological Aspects provides and assesses the latest research and developments surrounding the use of phytonutrients for the treatment of neurological disorders. The volume analyzes advances in phytonutrient isolation, characterization and therapeutic applications, giving particular emphasis to mechanisms and safety profiles. The book takes toxicological considerations into account, including adverse drug reactions, toxicokinetics and toxicodynamics. Sections cover bioactive compound classes and biosynthesis pathways, general considerations, including quality control, standardization, and technology, and toxicology. This title is a comprehensive work on the latest research in phytonutrients and neurological disorders that will be useful to researchers and medical practitioners. - Presents a comprehensive resource on phytonutrients and their relationship to neurological disorders - Analyzes the isolation, characterization and mechanisms of phytonutrients in neurology - Focuses on various signaling pathways followed by phytonutrients in neuroprotection - Gives the latest thinking on quality control parameters and specifications for phytonutrient study - Considers the toxicology of phytonutrients, including adverse drug reactions, toxicokinetics and toxicodynamics
Fruit And Vegetable Phytochemicals
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Author : Elhadi M. Yahia
language : en
Publisher: John Wiley & Sons
Release Date : 2017-08-29
Fruit And Vegetable Phytochemicals written by Elhadi M. Yahia and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-29 with Technology & Engineering categories.
Now in two volumes and containing more than seventy chapters, the second edition of Fruit and Vegetable Phytochemicals: Chemistry, Nutritional Value and Stability has been greatly revised and expanded. Written by hundreds of experts from across the world, the chapters cover diverse aspects of chemistry and biological functions, the influence of postharvest technologies, analysis methods and important phytochemicals in more than thirty fruits and vegetables. Providing readers with a comprehensive and cutting-edge description of the metabolism and molecular mechanisms associated with the beneficial effects of phytochemicals for human health, this is the perfect resource not only for students and teachers but also researchers, physicians and the public in general.
Gut Microbiota In Neurologic And Visceral Diseases
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Author : Tahira Farooqui
language : en
Publisher: Academic Press
Release Date : 2021-03-11
Gut Microbiota In Neurologic And Visceral Diseases written by Tahira Farooqui and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-11 with Medical categories.
Gut Microbiota in Neurologic and Visceral Diseases presents readers with comprehensive information on the involvement of microbiota in the pathogenesis of neurological disorders. Chapters cover the effect of microbiota on the development of visceral (obesity, type 2 diabetes, heart disease) and neurological disorders (Alzheimer's disease, Parkinson's, depression, anxiety, and autism). Sections focus on the molecular mechanisms and signal transduction processes associated with the links among microbiota-related visceral and neurological disorders. It is hoped that this discussion will not only integrate and consolidate knowledge in this field but will also jumpstart more studies on the involvement of microbiota in the pathogenesis of neurological disorders. - Reviews the relationship between gut microbiome, diseases and disorders - Discusses the relationship between diet, microbiota and inflammation - Includes neurodegenerative, neuropsychiatric and cardiovascular disorders - Covers diabetes, obesity and metabolic disorders - Identifies molecular mechanisms and signal transduction processes - Encompasses dietary fiber, fat, prebiotics and probiotics
Nanotechnology Horizons In Food Process Engineering
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Author : Megh R. Goyal
language : en
Publisher: CRC Press
Release Date : 2023-03-10
Nanotechnology Horizons In Food Process Engineering written by Megh R. Goyal and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-10 with Technology & Engineering categories.
Although nanotechnology has revolutionized fields such as medicine, genetics, biology, bioengineering, mechanics, and chemistry, its increasing application in the food industry is relatively recent in comparison. Nanotechnology in the food industry is now being explored for creating new flavors, extending food shelf life, and improving food protection and nutritional value, as well as for intelligent nutrient delivery systems, “smart” foods, contaminant detection nanodevices and nanosensors, advanced food processing, antimicrobial chemicals, encapsulation, and green nanomaterials. This new three-volume set addresses a multitude of topical issues and new developments in the field. Volume 1 focuses on food preservation, food packaging and sustainable agriculture, while Volume 2 looks at nanotechnology in food process engineering, applications of biomaterials in food products, and the use of modern nanotechnology for human health. The third volume explores the newest trends in nanotechnology for food applications and their application for improving food delivery systems. Together, these three volumes provide a comprehensive and in-depth look at the emerging status of nanotechnology in the food processing industry, explaining the benefits and drawbacks of various methodologies that will aid in the improvement and development of food product sourcing and food hygiene monitoring methods. Volume 2 discusses nanotechnology use in non-thermal techniques such as high-pressure processing (HPP), pulsed electric fields (PEFs), pulsed light, ultraviolet, microwave, ohmic heating, electrospinning, and nano- and microencapsulation. This volume looks at the role and application of minimal processing techniques such as ozone treatment, vacuum drying, osmotic dehydration, dense phase carbon dioxide treatment, and high-pressure assisted freezing. The successful applications of nanotechnologies on juices, meat and fish, fruits and vegetable slices, food surface, purees, milk and milk products, extraction, drying enhancement, and encapsulation of micro-macro nutrients are also considered. The volume also presents several computer-aided techniques that are emerging in the food processing sector, such as robotics, radio frequency identification (RFID), three-dimensional food printing, artificial intelligence, etc. Significant role of food properties in design of specific food and edible packaging films have been elucidated.
Insulin Resistance As A Risk Factor In Visceral And Neurological Disorders
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Author : Akhlaq A. Farooqui
language : en
Publisher: Academic Press
Release Date : 2020-03-20
Insulin Resistance As A Risk Factor In Visceral And Neurological Disorders written by Akhlaq A. Farooqui and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-20 with Medical categories.
Insulin Resistance as a Risk Factor in Visceral and Neurological Disorders provides an overview on the risk factors for insulin resistance in visceral and neurological disorders. The book focuses on molecular mechanisms and signal transduction processes associated with the links. The comprehensive information in this monograph will not only help in the early detection of insulin resistance related visceral and neurological disorders, but also promote the discovery of new drugs which may block or delay onset in elderly patients. Understanding these processes is important not only for patients, caregivers and health professionals, but also for health policymakers who must plan for national resources. - Presents the first comprehensive book dedicated to insulin resistance as a risk factor for neurological disorders - Focuses on the molecular mechanisms and signal transduction processes associated with insulin resistance - Discusses insulin resistance to heart disease, obesity, diabetes, stroke, Alzheimer's, Parkinson's, dementia and depression
Neurophytomedicine
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Author : Mithun Singh Rajput
language : en
Publisher: CRC Press
Release Date : 2024-01-29
Neurophytomedicine written by Mithun Singh Rajput and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-29 with Medical categories.
Neurological disorders categorized as neurodegenerative, neuropsychiatric, and neurotraumatic impose a substantial health burden and cause a frail impact on life attributes. The use of synthetic drugs can have undesirable side effects, making neurotherapeutics challenging. Research on neuroprotection aiming for the utilization of safer natural compounds; phytochemicals specifically – is a cutting-edge approach. NeuroPhytomedicine intends to present readers with a wide-ranging and state-of-the-art appearance at the beneficial properties of phytochemicals on various neurological ailments. It additionally contains sections explaining: Applications of phyto-nanotechnology in neurological ailments Phytoconstituents related deep learning and machine learning-based solutions for neurological disorders Epigenetic relevance pertaining to modulation by phytochemicals The goal of NeuroPhytomedicine is to give readers a thorough and up-to-date look at how phytochemicals affect the brain and neurological illnesses in a way that is helpful for research scholars, academicians, scientists, neuroscientists, physicians, and researchers from the pharmaceutical industry.