Plasma And Recombinant Blood Products In Medical Therapy
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Plasma And Recombinant Blood Products In Medical Therapy
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Author : Christopher V. Prowse
language : en
Publisher:
Release Date : 1992-06
Plasma And Recombinant Blood Products In Medical Therapy written by Christopher V. Prowse and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-06 with Medical categories.
Provides an introduction to the preparation and therapeutic use of blood products and the potential contribution of molecular biology. Focuses on understanding the molecular mechanisms of human physiology, disease and new medical techniques for clinical diagnosis and treatment.
Practical Transfusion Medicine
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Author : Michael F. Murphy
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-07
Practical Transfusion Medicine written by Michael F. Murphy and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-07 with Medical categories.
The fifth edition of this practical textbook on transfusion medicine has been thoroughly revised with the latest in scientific and technological developments and edited by a leading team of international expert haematologists, including new co-editor Mark H. Yazer MD. A succinct and user-friendly resource of transfusion medicine for clinicians, scientists and trainees with key points, charts and algorithms Discusses practice in blood centres and hospitals including regulatory aspects, transfusion safety, production and storage, donor care, and blood transfusion in a global context Coverage of cellular and tissue therapies and organ transplantation including stem cell collection and haematopoietic stem cell processing and storage Review of the development of the evidence-base for transfusion medicine Content on the clinical practice for transfusion and alternatives to transfusion
Hiv And The Blood Supply
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 1995-10-05
Hiv And The Blood Supply written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-10-05 with Medical categories.
During the early years of the AIDS epidemic, thousands of Americans became infected with HIV through the nation's blood supply. Because little reliable information existed at the time AIDS first began showing up in hemophiliacs and in others who had received transfusions, experts disagreed about whether blood and blood products could transmit the disease. During this period of great uncertainty, decision-making regarding the blood supply became increasingly difficult and fraught with risk. This volume provides a balanced inquiry into the blood safety controversy, which involves private sexual practices, personal tragedy for the victims of HIV/AIDS, and public confidence in America's blood services system. The book focuses on critical decisions as information about the danger to the blood supply emerged. The committee draws conclusions about what was doneâ€"and recommends what should be done to produce better outcomes in the face of future threats to blood safety. The committee frames its analysis around four critical area: Product treatmentâ€"Could effective methods for inactivating HIV in blood have been introduced sooner? Donor screening and referralâ€"including a review of screening to exlude high-risk individuals. Regulations and recall of contaminated bloodâ€"analyzing decisions by federal agencies and the private sector. Risk communicationâ€"examining whether infections could have been averted by better communication of the risks.
Production Of Plasma Proteins For Therapeutic Use
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Author : Joseph Bertolini
language : en
Publisher: John Wiley & Sons
Release Date : 2012-12-26
Production Of Plasma Proteins For Therapeutic Use written by Joseph Bertolini and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.
Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading experts and pioneers in the field, Production of Plasma Proteins for Therapeutic Use presents a comprehensive overview of the current state of knowledge about the function, use, and production of blood plasma proteins. In addition to details of the operational requirements for the production of plasma derivatives, the book describes the biology, development, research, manufacture, and clinical indications of essentially all plasma proteins with established clinical use or therapeutic potential. Production of Plasma Proteins for Therapeutic Use covers the key aspects of the plasma fractionation industry in five sections: Section 1: Introduction to Plasma Fractionation initially describes the history of transfusion and then covers the emergence of plasma collection and fractionation from its earliest days to the present time, with the commercial and not-for-profit sectors developing into a multi-billion dollar industry. Section 2: Plasma Proteins for Therapeutic Use contains 24 chapters dedicated to specific plasma proteins, including coagulation factors, albumin, immunoglobulin, and a comprehensive range of other plasma-derived proteins with therapeutic indications. Each chapter discusses the physiology, biochemistry, mechanism of action, and manufacture of each plasma protein including viral safety issues and clinical uses. Section 3: Pathogen Safety of Plasma Products examines issues and procedures for enhancing viral safety and reducing the risk of transmissible spongiform encephalopathy transmission. Section 4: The Pharmaceutical Environment Applied to Plasma Fractionation details the requirements and activities associated with plasma collection, quality assurance, compliance with regulatory requirements, provision of medical affairs support, and the manufacture of plasma products. Section 5: The Market for Plasma Products and the Economics of Fractionation reviews the commercial environment and economics of the plasma fractionation industry including future trends, highlighting regions such as Asia, which have the potential to exert a major influence on the plasma fractionation industry in the twenty-first century.
Alternative Approaches To Human Blood Resources In Clinical Practice
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Author : Cees Smit Sibinga
language : en
Publisher: Springer Science & Business Media
Release Date : 1998-09-30
Alternative Approaches To Human Blood Resources In Clinical Practice written by Cees Smit Sibinga and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-09-30 with Medical categories.
Currently blood is a volatile issue. The safety of blood and the quantification of transfusion risks have been dominant themes that have stimulated the development of alternative approaches in this rapidly developing area. In clinical medicine conventional blood and its components are used in supportive therapies dependent on the choice of apparent uncritical trigger factors. A compounding factor is depth of prospective clinical trials for evidence. Such trials in critical care areas would be of enormous value, not only in recording adverse effects and under-transfusion, but also indicating the value of decision analysis and cost-effectiveness in transfusion practice. Alternative approaches include the use of cytokines, growth factors, humanised monoclonal antibodies, recombinant plasma factors, and buffy coat derived natural human interferons. These are being increasingly implemented in the clinic. Solutions for oxygen transport are being developed and fibrinogen coated microcapsules are being investigated for thrombocytopenia. In surgical patients, various crystalloid and colloid combinations are explored as volume replacements. To avoid allogeneic transfusions, beneficial blood saving methods include various strategies, such as autologous deposits, normovolemic haemodilution and various agents including aprotinin, tranecamic acid, desmopressin and erythropoietin, but their use in hospital shows considerable variations. That umbilical cord blood could be a significant source of allogeneic stem cells in related and unrelated transplantation is illustrated by the increasing number of cord blood banks in Europe and elsewhere. Future blood resources are likely to face several challenges: immediate challenges relate to increased regulatory and political oversights; intermediate solutions would offer some improvements in public health and alleviate public fear but probably not address the economic challenges thrust upon the medical care system. As we approach the year 2000, the major concerns about transfusion medicine remain its logistics, safety and effectiveness. This theme is presented in the proceedings of the 22nd International Symposium on Blood Transfusion, developed in 21 up-to-date topics, collected and discussed in four sections. This book will be of timely value to students, professionals and all others interested or involved in the field of transfusion medicine, whether clinical or related.
Transfusion Therapy
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Author : Paul D. Mintz
language : en
Publisher: American Association of Blood Banks (AABB)
Release Date : 2005
Transfusion Therapy written by Paul D. Mintz and has been published by American Association of Blood Banks (AABB) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Anemia categories.
Principles Of Transfusion Medicine
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Author :
language : en
Publisher:
Release Date : 1996
Principles Of Transfusion Medicine written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Blood categories.
Trauma Induced Coagulopathy
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Author : Hunter B. Moore
language : en
Publisher: Springer Nature
Release Date : 2020-10-12
Trauma Induced Coagulopathy written by Hunter B. Moore and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-12 with Medical categories.
The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.
Patient Blood Management In Cardiac Surgery
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Author : Christian von Heymann
language : en
Publisher: Springer
Release Date : 2019-06-03
Patient Blood Management In Cardiac Surgery written by Christian von Heymann and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-03 with Medical categories.
This book provides a multidisciplinary approach to the maintenance of hemostasis and minimisation of blood loss in patients undergoing cardiac surgery. All aspects of patient blood management are covered that may contribute to a reduction in perioperative bleeding and transfusion requirements in cardiac surgery. This is achieved through practical cases and a theoretical background that gives a better understanding of patient hemostasis and the occurrence of bleeding complications. This book is relevant to cardiac surgeons, anesthesiologists, clinical perfusionists, hematologists and intensivists.
Transfusion Medicine
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Author : Jeffrey J. McCullough
language : en
Publisher: John Wiley & Sons
Release Date : 2011-12-27
Transfusion Medicine written by Jeffrey J. McCullough and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-27 with Medical categories.
Jeffrey McCullough offers a concise, clinically focused and practical approach to this important area of medicine. This book offers complete guidance on the full range of topics from donor recruitment, blood collection and storage, to testing and transfusing blood components, complications and transmissible diseases, as well as cellular engineering, therapeutic apheresis, and the role of hematopoietic growth factors. It is a good introduction to transfusion for hematology or oncology fellows and technologists specialising in blood banking.