Platelet Activating Factor In Endotoxin And Immune Diseases
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Platelet Activating Factor In Endotoxin And Immune Diseases
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Author : Dean A. Handley
language : en
Publisher: Marcel Dekker
Release Date : 1990
Platelet Activating Factor In Endotoxin And Immune Diseases written by Dean A. Handley and has been published by Marcel Dekker this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medical categories.
Endotoxin In Health And Disease
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Author : Helmut Brade
language : en
Publisher: CRC Press
Release Date : 1999-07-02
Endotoxin In Health And Disease written by Helmut Brade and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-07-02 with Science categories.
Offering a basis for further research into the interactions of hosts and pathogens, this work gathers up-to-date findings, and details basic structures, functions and immunology. It provides descriptions of a variety of experimental endotoxin neutralizing agents, as well as a guide to clinical research initiatives and the latest treatments.
Pathophysiology Of Reperfusion Injury
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Author : Dipak K. Das
language : en
Publisher: CRC Press
Release Date : 1992-10-16
Pathophysiology Of Reperfusion Injury written by Dipak K. Das and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-10-16 with Medical categories.
Pathophysiology of Reperfusion Injury presents the first integrated summary of the important areas of reperfusion injury. By covering reperfusion injury in the heart, lungs, liver, kidneys, and small bowel, the book demonstrates the interrelationships of these various aspects and concludes that they are all part of a natural and integrated whole. The leading investigators in the field address the potential biochemical, cellular, and molecular mechanisms of reperfusion injury, which will benefit all researchers working in this field.
Platelets And Their Factors
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Author : Franz von Bruchhausen
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Platelets And Their Factors written by Franz von Bruchhausen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Platelets playa fundamental, life-saving role in hemostasis and blood clotting at sites of vascular injury. Unwanted platelet activation and arterial thombus formation are, however, implicated in the onset of myocardial infarction, stroke, and other cardiovascular diseases. Acceptance that platelets play a major role in the pathogenesis of atherosclerosis including coronary heart disease has revolutionized the pharmacological treatment of cardiovascular diseases, and aspirin is now an essential antiplatelet drug and the golden standard for future developments. Yet the search for better and perhaps safer antiplatelet drugs is one of the most active areas of investigation in both basic and clinical research. Platelets, especially human platelets, have also emerged as one of the major models for the study of inter- and intracellular signal transduction pathways. Many biochemists, cell biologists, pharmacologists, pathologists, hematologists, and cardiologists find platelets useful for studying processes such as adhesion, inside-out and outside-in signalling through the plasma membrane, channels, calcium homeostasis, protein kinases, the network of intracellular signal transduction cascades, and the release of vasoactive substances. The aim of the editors has been to compile chapters summarizing the current state-of-the-art information on the biochemistry, cell biology, pharmacology, and physiologic and pathophysiologic roles of human platelets. We hope that this volume represents the major aspects of current platelet research although it is perhaps inevitable that certain areas are covered less thoroughly than others. We would like to acknowledge the excellent help and support of the Springer-Verlag staff, in particular that of Ms. Doris Walker.
Airways Smooth Muscle Neurotransmitters Amines Lipid Mediators And Signal Transduction
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Author : David Raeburn
language : en
Publisher: Birkhäuser
Release Date : 2012-12-06
Airways Smooth Muscle Neurotransmitters Amines Lipid Mediators And Signal Transduction written by David Raeburn and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Platelet Activating Factor And Related Lipid Mediators
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Author : F. Snyder
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Platelet Activating Factor And Related Lipid Mediators written by F. Snyder and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
Platelet-activating factor (PAF) is the commonly used name for a group of potent biologically active, ether-linked phospholipids, the alkylacetylglycerophospho cholines. Following the identification of the chemical structure of P AF in 1979, much progress has been made in our understanding of these phospholipid medi ators. This is particularly true from the points of view of their molecular structural requirements for expression of biological activity, their biosynthesis and cata bolism, their diverse range of biological activities, evidence for their specific recep tors at the cell surface, the development of specific antagonists for use in receptor studies and for testing as potential anti-PAF drugs, and implications about their involvement in health and disease. Chapters in this book cover the current status of these general areas of PAF research. Although an enormous amount of information has been published about this interesting new type of phospholipid mediators, questions about their mechanism of action, regulatory controls, and the precise role and relative importance of P AF in specific diseases and physiological functions remain to be answered. Since the 1979 discovery, the PAF field has brought together scientists from a variety of different biomedical disciplines. The diversity of scientists now in PAF research is very apparent from the number of P AF publications appearing in a wide array of scientific journals, ranging from molecular biology to clinical medicine. Publications related to PAF continue to increase at an amazingly rapid rate, with the pace reminiscent of the period following the discovery of prostaglandins.
Endotoxin In Health And Disease
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Author : Helmut Brade
language : en
Publisher: CRC Press
Release Date : 2020-10-28
Endotoxin In Health And Disease written by Helmut Brade and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-28 with Science categories.
Offering a basis for further research into the interactions of hosts and pathogens, this work gathers up-to-date findings, and details basic structures, functions and immunology. It provides descriptions of a variety of experimental endotoxin neutralizing agents, as well as a guide to clinical research initiatives and the latest treatments.
Handbook Of Paf And Paf Antagonists
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Author : lPierre Braquet
language : en
Publisher: CRC Press
Release Date : 2019-06-13
Handbook Of Paf And Paf Antagonists written by lPierre Braquet and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-13 with Medical categories.
Published in 1991: Since its characterization in the 1970s from antigen-stimulated rabbit basophils, platelet-activating factor (PAF) has been demonstrated to be produced by, and act upon, a variety of cell types. PAF antagonists, which have been obtained from both natural sources and chemical synthesis, now represent a new class of therapeutic agents and may provide new prospects for treating several major pathologies, particularly shock, ischemia and asthma. This book provides a unique overview of the chemistry, molecular modeling, pharmacology, and clinical potential of the major classes of natural and synthetic PAF antagonists. Compounds reviewed include the ginkgolides, diketopiperazines, neolignans, hetrazepines, cyclic and 1,3-dioxolan derived PAF analogs, pyrrolo[1,2-c]thiazoles, imidazo[2,1-a]isoquinolines and pyridoquinazoline carboxamides. Consisting of 12 chapters written by leading experts in PAF antagonist research, this book is essential reading for students, researchers, clinicians, and medical practitioners involved in this rapidly developing field of biomedical research.
Platelet Activating Factor Acetylhydrolases Paf Ah
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-12-01
Platelet Activating Factor Acetylhydrolases Paf Ah written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-01 with Science categories.
This volume of The Enzymes summarizes the most important discoveries associated with a group of enzymes that play an important role in normal biological processes as presented and discussed by leaders authorities in the field. Contributions from leading authorities Informs and updates on all the latest developments in the field of enzymes
Inflammatory Cells And Mediators In Bronchial Asthma
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Author : Devendra K. Agrawal
language : en
Publisher: CRC Press
Release Date : 2020-10-28
Inflammatory Cells And Mediators In Bronchial Asthma written by Devendra K. Agrawal and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-28 with Medical categories.
Inflammatory Cells and Mediators in Bronchial Asthma provides reviews and summaries regarding state-of-the-art articles that examine the role of various inflammatory cells and their mediators in the pathogenesis of asthma. Topics include pharmacological and biochemical regulation of the airways; involvement of key inflammatory cells and the release and effect of their mediators in airway function; and the characteristics of receptors for leukotriene B4, C4, and D4, adenosine, platelet-activating factor, sensory and inflammatory peptides, and the effect of various anti-asthmatic drugs on airway inflammation. Physicians, allergists, immunologists, and pulmonary disease research scientists will find this book to be an invaluable reference resource.