Population Epigenetics
DOWNLOAD
Download Population Epigenetics PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Population Epigenetics book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Population Epigenetics
DOWNLOAD
Author : Paul Haggarty
language : en
Publisher: Humana
Release Date : 2017-02-17
Population Epigenetics written by Paul Haggarty and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-17 with Medical categories.
This detailed volume focuses on population epigenetics, which is of increasing interest to policy makers searching for explanations for complex epidemiological observations and conceptual models on which to base interventions. With a concentration on DNA methylation, the emphasis is on the most commonly studied epigenetic phenomenon that is most amenable to further study. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. /divAuthoritative and practical, Population Epigenetics: Methods and Protocols aims to aid population researchers in exploiting the latest insights into epigenetics to improve our understanding of the factors that influence human health and longevity.
Environmental Epigenetics In Toxicology And Public Health
DOWNLOAD
Author : Rebecca Fry
language : en
Publisher: Academic Press
Release Date : 2020-10-18
Environmental Epigenetics In Toxicology And Public Health written by Rebecca Fry and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-18 with Medical categories.
Environmental Epigenetics in Toxicology and Public Health provides in-depth discussions of the suite of complex environmental factors shown to impact epigenetic components within the cell, as well as evidence that these epigenetic modifications are tied to early and later life health effects. This book offers a translational research perspective, highlighting both in vivo and human population-based evidence for ties between the environment, the epigenome, and health outcomes, with an emphasis on evidence for transgenerational effects of exposures, as well as developmental windows of susceptibility to environmentally-linked epigenetic effects. This volume in the Translational Epigenetics series aides in the development of new therapeutic options meant to reverse inappropriate epigenetic alterations, helping researchers in their efforts prevent and treat a variety of chronic diseases tied to environmental exposures. Offers a thorough discussion of the environmental factors influencing epigenetic mechanisms in early and late life, and in transgenerational inheritance Examines both animal model and human population-based research in environmental epigenetics, highlighting developmental windows of vulnerability to epigenetic modification Features contributions from international experts in the field
Epigenetic Epidemiology
DOWNLOAD
Author : Karin B. Michels
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-01-03
Epigenetic Epidemiology written by Karin B. Michels and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-03 with Medical categories.
The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored. This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of of age and environmental factors on shaping the epigenome, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis. With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics!
Epigenetics And Complex Traits
DOWNLOAD
Author : Anna K. Naumova
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-09-17
Epigenetics And Complex Traits written by Anna K. Naumova and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-17 with Medical categories.
This book will provide an overview of basic epigenetic phenomena; interaction between epigenetic and genetic factors; and the influence of epigenetic factors on inheritance. Epigenetic states may contribute to the penetrance of genetic polymorphisms or mutations and thereby modify inheritance patterns. This may result in non‐Mendelian inheritance of genetic traits such as observed in common human disease. The relationship between epigenetics and genetics, however, has not been comprehensively summarized yet. The topic is being more and more appreciated lately due to considerable advances in genomic and epigenomic approaches to study the origins of human disease. The editors will focus not only on describing epigenetic characteristics, mechanisms and results, but also on how considerations of epigenetics can alter interpretation and analysis of risks for complex traits. This book will be a resource for those who have been working in human genetics or analysis of human genetic data and are studying the impact of epigenetics on inheritance. An overview will be given of the impacts of inter‐individual variation in epigenetic states from major changes (errors in genomic imprinting) that cause congenital developmental defects to subtle changes and their impact on complex traits. The editors will discuss the relationship between epigenetic changes and genetic changes in human disease. Several chapters will also focus on statistical analysis of epigenetics effects, either in human disease genetic studies, or in population genetics.
Epigenetics In Society
DOWNLOAD
Author : Windsor Epigenetics Study Group
language : en
Publisher: University of Windsor
Release Date : 2015-10-26
Epigenetics In Society written by Windsor Epigenetics Study Group and has been published by University of Windsor this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-26 with Science categories.
This is a book written by students of diverse disciplines, and intended for students and educated lay people. We intend this book to serve several functions. First, we want to make the field of epigenetics accessible to lay readers. Second, and more importantly, we want to excite further interest and concern regarding the social, ethical, legal, health, and policy implications that this field will have for all arenas of our lives. Third, we want to arm our readers with knowledge and wariness so that they can understand and critique the nuanced debates that will inevitably arise when costs and benefits must be weighed: while the effects of epigenetics upon us as individuals may be subtle, the demographic implications and costs are huge.
Twin And Family Studies Of Epigenetics
DOWNLOAD
Author : Shuai Li
language : en
Publisher: Academic Press
Release Date : 2021-08-19
Twin And Family Studies Of Epigenetics written by Shuai Li and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-19 with Medical categories.
Twin and Family Studies of Epigenetics, Volume 27, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, twin and family studies are employed to examine causes of epigenetic variation, the relationship between epigenetic modifications and mental illness, cancers, cardiovascular disease, diabetes, obesity, high blood pressure, and more. Emerging research methods applied in twin and family studies discussed include imaging epigenetics, exposure-specific DNA methylation changes, and unravelling time trends in epigenetic effects. Offers a practical, interdisciplinary approach across epigenetics, epidemiology and various disease specialties Applies epigenetic twin and family studies to determine the relationship between epigenetics and mental illness, cancers, cardiovascular disease, diabetes, obesity and high blood pressure, among other diseases and disorders Features chapter contributions from a wide range of international researchers in the field
Transmission And Population Genetics
DOWNLOAD
Author : Benjamin A. Pierce
language : en
Publisher: Macmillan
Release Date : 2006-01-09
Transmission And Population Genetics written by Benjamin A. Pierce and has been published by Macmillan this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-09 with Science categories.
This new brief version of Benjamin Pierce’s Genetics: A Conceptual Approach, Second Edition, responds to a growing trend of focusing the introductory course on transmission and population genetics and covering molecular genetics separately. The book is comprised of following chapters an case studies from Pierce's complete text: 1. Introduction to Genetics 2. Chromosomes and Cellular Reproduction 3. Basic Principles of Heredity 4. Sex Determination and Sex-Linked Characteristics 5. Extensions and Modifications of Basic Principles 6. Pedigree Analysis and Applications INTEGRATIVE CASE STUDY Phenylketonuria: Part I 7. Linkage, Recombination, and Eukaryotic Gene Mapping 8. Bacterial and Viral Genetic Systems 9. Chromosome Variation INTEGRATIVE CASE STUDY Phenylketonuria: Part II 22. Quantitative Genetics 23. Population Genetics and Molecular Evolution INTEGRATIVE CASE STUDY Phenylketonuria: Part III
Epigenetics Of Aging
DOWNLOAD
Author : Trygve O. Tollefsbol
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-11-11
Epigenetics Of Aging written by Trygve O. Tollefsbol and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Medical categories.
Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.
Epigenetics
DOWNLOAD
Author : Benedikt Hallgrímsson
language : en
Publisher: Univ of California Press
Release Date : 2011-04-11
Epigenetics written by Benedikt Hallgrímsson and has been published by Univ of California Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-11 with Science categories.
“If you want to understand evolution, you need to understand the murky world of epigenetics. A hearty congratulations should be paid to Hallgrimsson and Hall, who provide reliable and steady illumination.”-Bernard Wood, Center for the Advanced Study of Hominid Paleobiology, George Washington University
Lamarck S Revenge
DOWNLOAD
Author : Peter Ward
language : en
Publisher: Bloomsbury Publishing USA
Release Date : 2018-08-14
Lamarck S Revenge written by Peter Ward and has been published by Bloomsbury Publishing USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-14 with Science categories.
A riveting explanation of epigenetics, offering startling insights into our inheritable traits. In the 1700s, Jean-Baptiste Lamarck first described epigenetics to explain the inheritance of acquired characteristics; however, his theory was supplanted in the 1800s by Darwin's theory of evolution by natural selection through heritable genetic mutations. But natural selection could not adequately explain how rapidly species re-diversified and repopulated after mass extinctions. Now advances in the study of DNA and RNA have resurrected epigenetics, which can create radical physical and physiological changes in subsequent generations by the simple addition of a single small molecule, thus passing along a propensity for molecules to attach in the same places in the next generation. Epigenetics is a complex process, but paleontologist and astrobiologist Peter Ward breaks it down for general readers, using the epigenetic paradigm to reexamine how the history of our species-from deep time to the outbreak of the Black Plague and into the present-has left its mark on our physiology, behavior, and intelligence. Most alarming are chapters about epigenetic changes we are undergoing now triggered by toxins, environmental pollutants, famine, poor nutrition, and overexposure to violence. Lamarck's Revenge is an eye-opening and provocative exploration of how traits are inherited, and how outside influences drive what we pass along to our progeny.