Potential Industrial Carcinogens And Mutagens
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Potential Industrial Carcinogens And Mutagens
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Author : Lawrence Fishbein
language : en
Publisher:
Release Date : 1977
Potential Industrial Carcinogens And Mutagens written by Lawrence Fishbein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Carcinogens categories.
Potential Industrial Carcinogens And Mutagens
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Author : L. Fishbein
language : en
Publisher: Elsevier
Release Date : 2011-08-30
Potential Industrial Carcinogens And Mutagens written by L. Fishbein and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-30 with Science categories.
Potential Industrial Carcinogens and Mutagens
Potential Industrial Carcinogens And Mutagens
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Author : Lawrence Fishbein
language : en
Publisher:
Release Date : 1981
Potential Industrial Carcinogens And Mutagens written by Lawrence Fishbein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with categories.
Potential Industrial Carcinogens And Mutagens
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Author : Lawrence Fishbein
language : en
Publisher:
Release Date : 1977
Potential Industrial Carcinogens And Mutagens written by Lawrence Fishbein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Carcinogens categories.
Living In A Chemical World
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Author : Cesare Maltoni
language : en
Publisher:
Release Date : 1988
Living In A Chemical World written by Cesare Maltoni and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Cancer categories.
Occupational Exposures
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Author : Frances Alston
language : en
Publisher: CRC Press
Release Date : 2023-02-03
Occupational Exposures written by Frances Alston and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-03 with Technology & Engineering categories.
Occupational Exposures: Chemical Carcinogens and Mutagens offers a focused emphasis on chemical exposures associated with carcinogenic and mutagenic impacts along with associated controls for mitigating and controlling exposures. It discusses a range of topics including hematopoietic system impact, reproductive system impact, inorganic compounds, halogenated compounds, carbamates, polycyclic aromatic hydrocarbons, aromatic amines, product elimination and substation, exposure control methods, and human biological impact. Presents a comprehensive account of carcinogens and mutagens for occupational and environmental health professionals Covers preventive measures and controls for carcinogens and mutagens Discusses exposure controls, exposure pathways, impacts, and treatments The book is ideal for professionals and graduate students in the fields of occupational health and safety, industrial engineering, and chemical engineering.
Mutagenicity Carcinogenicity And Teratogenicity Of Industrial Pollutants
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Author : Micheline Kirsch-Volders
language : en
Publisher: Springer
Release Date : 1984
Mutagenicity Carcinogenicity And Teratogenicity Of Industrial Pollutants written by Micheline Kirsch-Volders and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Medical categories.
This book is intended for anyone who cares about the health of people exposed to industrial pollutants. Attention is given to those pollutants which present a possible risk to the genetic material of exposed workers. Chapters are devoted to heavy metals such as arsenic, beryllium, cadmium, chromium, lead, mercury, nickel, etc.; insecticides (chlorinated, organophosphorus, and carbonate insecticides); monomers such as vinyl-chloride, acrylonitrile, styrene, vinylidene chloride, butadiene, chlorobutadiene, hexachlorobuta diene, etc.; and halogenated hydrocarbon solvents such as chloroform, carbon tetrachloride, trichloroethylene, I, 2-dichloroethane, tetrachloroethyl ene, dichloromethane, and I, I, I-trichloroethane. The main aim of this work is to provide the physician, the biologist, the pharmacologist, or anyone involved in genetic toxicology with a useful compendium of up-to-date information and references. Efforts are made to open the field to nonspecialists. An introductory chapter deals with the mechanisms whereby a given compound, reaching genetic material, either directly or indirectly, may increase the risk of a cancer developing in the exposed individual and of abnormalities being passed on to his or her progeny. Efforts are also made to allow easy and efficient reading for those who are not interested in detailed results. Comparative tables provide the following data on the compounds studied: chemical properties, production, occurrence, accepted standards in the industry, and positive or negative results with different test systems. Finally, senior research workers might find good descriptions in this book of the most recent results from mutagenesis and carcinogenesis testing in plant, nonmammalian, and mammalian systems.
Carcinogens And Anticarcinogens In The Human Diet
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1996-02-12
Carcinogens And Anticarcinogens In The Human Diet written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-02-12 with Nature categories.
Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.
How Tobacco Smoke Causes Disease
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Author :
language : en
Publisher:
Release Date : 2010
How Tobacco Smoke Causes Disease written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Government publications categories.
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Mutagenic Impurities
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Author : Andrew Teasdale
language : en
Publisher: John Wiley & Sons
Release Date : 2022-02-15
Mutagenic Impurities written by Andrew Teasdale and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-15 with Medical categories.
Learn to implement effective control measures for mutagenic impurities in pharmaceutical development In Mutagenic Impurities: Strategies for Identification and Control, distinguished chemist Andrew Teasdale delivers a thorough examination of mutagenic impurities and their impact on the pharmaceutical industry. The book incorporates the adoption of the ICH M7 guideline and focuses on mutagenic impurities from both a toxicological and analytical perspective. The editor has created a primary reference for any professional or student studying or working with mutagenic impurities and offers readers a definitive narrative of applicable guidelines and practical, tested solutions. It demonstrates the development of effective control measures, including chapters on the purge tool for risk assessment. The book incorporates a discussion of N-Nitrosamines which was arguably the largest mutagenic impurity issue ever faced by the pharmaceutical industry, resulting in the recall of Zantac and similar drugs resulting from N-Nitrosamine contamination. Readers will also benefit from the inclusion of: A thorough introduction to the development of regulatory guidelines for mutagenic and genotoxic impurities, including a historical perspective on the development of the EMEA guidelines and the ICH M7 guideline An exploration of in silico assessment of mutagenicity, including use of structure activity relationship evaluation as a tool in the evaluation of the genotoxic potential of impurities A discussion of a toxicological perspective on mutagenic impurities, including the assessment of mutagenicity and examining the mutagenic and carcinogenic potential of common synthetic reagents Perfect for chemists, analysts, and regulatory professionals, Mutagenic Impurities: Strategies for Identification and Control will also earn a place in the libraries of toxicologists and clinical safety scientists seeking a one-stop reference on the subject of mutagenic impurity identification and control.