Practical Techniques For Laboratory Analysis
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Analytical Techniques For Clinical Chemistry
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Author : Sergio Caroli
language : en
Publisher: Wiley
Release Date : 2012-07-31
Analytical Techniques For Clinical Chemistry written by Sergio Caroli and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-31 with Science categories.
Discover how analytical chemistry supports the latest clinical research This book details the role played by analytical chemistry in fostering clinical research. Readers will discover how a broad range of analytical techniques support all phases of clinical research, from early stages to the implementation of practical applications. Moreover, the contributing authors' careful step-by-step guidance enables readers to better understand standardized techniques and steer clear of everyday problems that can arise in the lab. Analytical Techniques for Clinical Chemistry opens with an overview of the legal and regulatory framework governing clinical lab analysis. Next, it details the latest progress in instrumentation and applications in such fields as biomonitoring, diagnostics, food quality, biomarkers, pharmaceuticals, and forensics. Comprised of twenty-five chapters divided into three sections exploring Fundamentals, Selected Applications, and Future Trends, the book covers such critical topics as: Uncertainty in clinical chemistry measurements Metal toxicology in clinical, forensic, and chemical pathology Role of analytical chemistry in the safety of drug therapy Atomic spectrometric techniques for the analysis of clinical samples Biosensors for drug analysis Use of X-ray techniques in medical research Each chapter is written by one or more leading pioneers and experts in analytical chemistry. Contributions are based on a thorough review and analysis of the current literature as well as the authors' own firsthand experiences in the lab. References at the end of each chapter serve as a gateway to the literature, enabling readers to explore individual topics in greater depth. Presenting the latest achievements and challenges in the field, Analytical Techniques for Clinical Chemistry sets the foundation for future advances in laboratory research techniques.
Practical Techniques For Laboratory Analysis
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Author : James A. Poppiti
language : en
Publisher: CRC Press
Release Date : 1994-07-27
Practical Techniques For Laboratory Analysis written by James A. Poppiti and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-07-27 with Science categories.
This book presents a detailed overview of day-to-day operations of laboratories. Commercial laboratories that cater to the environmental community are emphasized. The book is divided into three parts: laboratory management, practical solutions to common laboratory problems, and suggestions for increasing laboratory productivity.
Practical Instrumental Analysis
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Author : Sergio Petrozzi
language : en
Publisher: John Wiley & Sons
Release Date : 2012-09-24
Practical Instrumental Analysis written by Sergio Petrozzi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-24 with Science categories.
This practical book in instrumental analytics conveys an overview of important methods of analysis and enables the reader to realistically learn the (principally technology-independent) working techniques the analytical chemist uses to develop methods and conduct validation. What is to be conveyed to the student is the fact that analysts in their capacity as problem-solvers perform services for certain groups of customers, i.e., the solution to the problem should in any case be processed in such a way as to be "fit for purpose". The book presents sixteen experiments in analytical chemistry laboratory courses. They consist of the classical curriculum used at universities and universities of applied sciences with chromatographic procedures, atom spectrometric methods, sensors and special methods (e.g. field flow fractionation, flow injection analysis and N-determination according to Kjeldahl). The carefully chosen combination of theoretical description of the methods of analysis and the detailed instructions given are what characterizes this book. The instructions to the experiments are so detailed that the measurements can, for the most part, be taken without the help of additional literature. The book is complemented with tips for effective literature and database research on the topics of organization and the practical workflow of experiments in analytical laboratory, on the topic of the use of laboratory logs as well as on writing technical reports and grading them (Evaluation Guidelines for Laboratory Experiments). A small introduction to Quality Management, a brief glance at the history of analytical chemistry as well as a detailed appendix on the topic of safety in analytical laboratories and a short introduction to the new system of grading and marking chemicals using the "Globally Harmonized System of Classification and Labelling of Chemicals (GHS)", round off this book. This book is therefore an indispensable workbook for students, internship assistants and lecturers (in the area of chemistry, biotechnology, food technology and environmental technology) in the basic training program of analytics at universities and universities of applied sciences.
Diagnostic Samples From The Patient To The Laboratory
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Author : Walter G. Guder
language : en
Publisher: John Wiley & Sons
Release Date : 2014-07-22
Diagnostic Samples From The Patient To The Laboratory written by Walter G. Guder and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-22 with Medical categories.
This fourth, updated edition contains the latest developments in analytical techniques. An international team of authors summarizes the information on biological influences, analytical interferences and on the variables affecting the collection, transport and storage, as well as preparation of samples. In so doing, they cover age, gender, race, pregnancy, diet, exercise and altitude, plus the effects of stimulants and drugs. National and international standards are described for sampling procedures, transport, sample identification and all safety aspects, while quality assurance procedures are shown for total laboratory management. In addition, this practical book contains a glossary as well as a separate list of analytes containing the available data on reference intervals, biological half-life times, stability and influence and interference factors. For everyone involved in patient care and using or performing laboratory tests.
Method Validation In Pharmaceutical Analysis
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Author : Joachim Ermer
language : en
Publisher: John Wiley & Sons
Release Date : 2014-08-27
Method Validation In Pharmaceutical Analysis written by Joachim Ermer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-27 with Medical categories.
This second edition of a global bestseller has been completely redesigned and extensively rewritten to take into account the new Quality by Design (QbD) and lifecycle concepts in pharmaceutical manufacturing. As in the first edition, the fundamental requirements for analytical method validation are covered, but the second edition describes how these are applied systematically throughout the entire analytical lifecycle. QbD principles require adoption of a systematic approach to development and validation that begin with predefined objectives. For analytical methods these predefined objectives are established as an Analytical Target Profile (ATP). The book chapters are aligned with recently introduced standards and guidelines for manufacturing processes validation and follow the three stages of the analytical lifecycle: Method Design, Method Performance Qualification, and Continued Method Performance Verification. Case studies and examples from the pharmaceutical industry illustrate the concepts and guidelines presented, and the standards and regulations from the US (FDA), European (EMA) and global (ICH) regulatory authorities are considered throughout. The undisputed gold standard in the field.
The Laboratory Computer
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Author : John Dempster
language : en
Publisher: Academic Press
Release Date : 2001-07-10
The Laboratory Computer written by John Dempster and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-10 with Computers categories.
The Laboratory Computer: A Practical Guide for Physiologists and Neuroscientists introduces the reader to both the basic principles and the actual practice of recording physiological signals using the computer. It describes the basic operation of the computer, the types of transducers used to measure physical quantities such as temperature and pressure, how these signals are amplified and converted into digital form, and the mathematical analysis techniques that can then be applied. It is aimed at the physiologist or neuroscientist using modern computer data acquisition systems in the laboratory, providing both an understanding of how such systems work and a guide to their purchase and implementation. The key facts and concepts that are vital for the effective use of computer data acquisition systems A unique overview of the commonly available laboratory hardware and software, including both commercial and free software A practical guide to designing one's own or choosing commercial data acquisition hardware and software
A Practical Guide To Instrumental Analysis
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Author : Erno Pungor
language : en
Publisher: CRC Press
Release Date : 1994-10-19
A Practical Guide To Instrumental Analysis written by Erno Pungor and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-10-19 with Science categories.
A Practical Guide to Instrumental Analysis covers basic methods of instrumental analysis, including electroanalytical techniques, optical techniques, atomic spectroscopy, X-ray diffraction, thermoanalytical techniques, separation techniques, and flow analytical techniques. Each chapter provides a brief theoretical introduction followed by basic and special application experiments. This book is ideal for readers who need a knowledge of special techniques in order to use instrumental methods to conduct their own analytical tasks.
Practical Approaches To Method Validation And Essential Instrument Qualification
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Author : Chung Chow Chan
language : en
Publisher: Wiley
Release Date : 2010-09-27
Practical Approaches To Method Validation And Essential Instrument Qualification written by Chung Chow Chan and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-27 with Science categories.
Practical approaches to ensure that analytical methods and instruments meet GMP standards and requirements Complementing the authors' first book, Analytical Method Validation and Instrument Performance Verification, this new volume provides coverage of more advanced topics, focusing on additional and supplemental methods, instruments, and electronic systems that are used in pharmaceutical, biopharmaceutical, and clinical testing. Readers will gain new and valuable insights that enable them to avoid common pitfalls in order to seamlessly conduct analytical method validation as well as instrument operation qualification and performance verification. Part 1, Method Validation, begins with an overview of the book's risk-based approach to phase appropriate validation and instrument qualification; it then focuses on the strategies and requirements for early phase drug development, including validation of specific techniques and functions such as process analytical technology, cleaning validation, and validation of laboratory information management systems Part 2, Instrument Performance Verification, explores the underlying principles and techniques for verifying instrument performance—coverage includes analytical instruments that are increasingly important to the pharmaceutical industry, such as NIR spectrometers and particle size analyzers—and offers readers a variety of alternative approaches for the successful verification of instrument performance based on the needs of their labs At the end of each chapter, the authors examine important practical problems and share their solutions. All the methods covered in this book follow Good Analytical Practices (GAP) to ensure that reliable data are generated in compliance with current Good Manufacturing Practices (cGMP). Analysts, scientists, engineers, technologists, and technical managers should turn to this book to ensure that analytical methods and instruments are accurate and meet GMP standards and requirements.
Sampling And Sample Preparation
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Author : Markus Stoeppler
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Sampling And Sample Preparation written by Markus Stoeppler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The significant progress achieved in modern instrumental analysis has led to a continuous lowering of detection limits and improved precision. This should in principle permit the reliable and extremely precise analysis of trace compounds mainly trace elements, at levels down to the lowest natural concentrations. However, the frequently observed very high discrepancies between the analyt ical results of different laboratories as well as the deviations from true values are, regrettably, still common in analytical practice. Basic methodological errors at the determination step can usually be minimized or even avoided by carefully per formed quality control measures - e. g. by interlaboratory comparisons and the proper use of certified reference materials. The most severe and often under estimated error sources, however, are those connected with the whole and often extremely complex sampling process, and also to a lesser extent, with sample pre paration prior to analysis. Thus, for these initial steps of an analytical procedure particular experience is needed, as well as a detailed knowledge of the interrela tions between these steps, which always have to be applied with the utmost care. In collaboration with a number of very experienced colleagues working in dif book has tried to contribute to a better ferent research areas, the editor of this understanding of these particular error sources and how they can be overcome in a series of training courses held during the last decade at the "Haus der Technik", Essen, Germany.
Analytical Techniques In Forensic Science
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Author : Rosalind Wolstenholme
language : en
Publisher: John Wiley & Sons
Release Date : 2020-10-29
Analytical Techniques In Forensic Science written by Rosalind Wolstenholme and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-29 with Medical categories.
An in-depth text that explores the interface between analytical chemistry and trace evidence Analytical Techniques in Forensic Science is a comprehensive guide written in accessible terms that examines the interface between analytical chemistry and trace evidence in forensic science. With contributions from noted experts on the topic, the text features a detailed introduction analysis in forensic science and then subsequent chapters explore the laboratory techniques grouped by shared operating principles. For each technique, the authors incorporate specific theory, application to forensic analytics, interpretation, forensic specific developments, and illustrative case studies. Forensic techniques covered include UV-Vis and vibrational spectroscopy, mass spectrometry and gas and liquid chromatography. The applications reviewed include evidence types such as fibers, paint, drugs and explosives. The authors highlight data collection, subsequent analysis, what information has been obtained and what this means in the context of a case. The text shows how analytical chemistry and trace evidence can problem solve the nature of much of forensic analysis. This important text: Puts the focus on trace evidence and analytical science Contains case studies that illustrate theory in practice Includes contributions from experts on the topics of instrumentation, theory, and case examples Explores novel and future applications for analytical techniques Written for undergraduate and graduate students in forensic chemistry and forensic practitioners and researchers, Analytical Techniques in Forensic Science offers a text that bridges the gap between introductory textbooks and professional level literature.