Precision Medicine In Pediatric Health
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Precision Medicine In Pediatric Health
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Author : Olaf Bodamer
language : en
Publisher: Academic Press
Release Date : 2020-05-01
Precision Medicine In Pediatric Health written by Olaf Bodamer and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-01 with Science categories.
Precision Medicine in Pediatric Health is an invaluable resource on state-of-the-art tools, technologies and social and ethical issues involved in fully realizing precision medicine in new pediatric research and healthcare. The book adopts a holistic approach that is grounded in key learning points and practical case studies of interest to interdisciplinary teams of researchers and clinicians working in pediatrics. Chapters provide a thorough introduction to basic principles of precision medicine, its growing role in research and clinical care, relevant technologies and digital health. From there, the book examines best practices and offers support for implementing precision medicine in research and clinical settings. Chapters are devoted to varying specialties, such as prenatal and fetal health, oncology, cardiology, neurology, rare diseases, developmental disorders, and precision therapeutics, including small molecule and gene and cell-based therapies. These sections are followed by a close look at ethical, legal and social implications of precision medicine in pediatrics, patient perspectives and next steps in research and clinical translation. Presents succinct commentary and key learning points that support the translation of precision and genomic medicine Highlights the practical use of precision medicine in the management of pediatric patients Provides a comprehensive volume that is written and edited by leading researchers, clinicians and scientists
Precision Medicine A Multidisciplinary Approach
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Author : Joel J. Heidelbaugh
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-12-18
Precision Medicine A Multidisciplinary Approach written by Joel J. Heidelbaugh and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-18 with Medical categories.
The Clinics Collections titles take a multidisciplinary approach to today’s practice of medicine, selecting the most recent and relevant articles from the Clinics series and combining them into a single source of information on a focused topic. Articles are chosen from multiple Clinics to highlight the range of specialties covering major medical issues, delivering the information needed for successful interdisciplinary teamwork and effective patient care. Written from a variety of medical perspectives, these articles offer deeper insight into how each specialty cares for its patients and provide a unique entry into sharing best concepts for the entire medical team. Clinics Collections: Precision Medicine draws from Elsevier’s Clinics Review Articles database to provide today’s medical teams with practical clinical advice and insights on this timely medical model. It guides readers on how to apply current primary research findings to everyday practice, keep up with new and improved treatment methods, and improve patient outcomes. Areas of focus include breast cancer, lung cancer, melanoma, arthritis, sleep medicine, and pediatric oncology. Each article begins with keywords and key points for immediate access to the most critical information. Articles are presented in an easy-to-digest and concisely worded format.
Precision Medicine In Pediatrics
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Author : Jian Gao
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-22
Precision Medicine In Pediatrics written by Jian Gao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-22 with Science categories.
Discovering Precision Health
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Author : Lloyd Minor
language : en
Publisher: John Wiley & Sons
Release Date : 2020-01-23
Discovering Precision Health written by Lloyd Minor and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-23 with Medical categories.
Today we are on the brink of a much-needed transformative moment for health care. The U.S. health care system is designed to be reactive instead of preventive. The result is diagnoses that are too late and outcomes that are far worse than our level of spending should deliver. In recent years, U.S. life expectancy has been declining. Fundamental to realizing better health, and a more effective health care system, is advancing the disruptive thinking that has spawned innovation in Silicon Valley and throughout the world. That's exactly what Stanford Medicine has done by proposing a new vision for health and health care. In Discovering Precision Health, Lloyd Minor and Matthew Rees describe a holistic approach that will set health care on the right track: keep people healthy by preventing disease before it starts and personalize the treatment of individuals precisely, based on their specific profile. With descriptions of the pioneering work undertaken at Stanford Medicine, complemented by fascinating case studies of innovations from entities including the Chan Zuckerberg Biohub, GRAIL, and Impossible Foods, Minor and Rees present a dynamic vision for the future of individual health and health care. Youll see how tools from smartphone technology to genome sequencing to routine blood tests are helping avert illness and promote health. And you'll learn about the promising progress already underway in bringing greater precision to the process of predicting, preventing, and treating a range of conditions, including allergies, mental illness, preterm birth, cancer, stroke, and autism. The book highlights how biomedical advances are dramatically improving our ability to treat and cure complex diseases, while emphasizing the need to devote more attention to social, behavioral, and environmental factors that are often the primary determinants of health. The authors explore thought-provoking topics including: The unlikely role of Google Glass in treating autism How gene editing can advance precision in treating disease What medicine can learn from aviation liHow digital tools can contribute to health and innovation Discovering Precision Health showcases entirely new ways of thinking about health and health care and can help empower us to lead healthier lives.
Advances In Pediatrics 2019
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Author : Carol D. Berkowitz
language : en
Publisher: Elsevier Health Sciences
Release Date : 2019-06-23
Advances In Pediatrics 2019 written by Carol D. Berkowitz and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-23 with Medical categories.
Each year, Advances in Pediatrics focuses on providing current clinical information on important topics in pediatrics. Dr. Carol Berkowitz and her editorial board, comprised of top experts in the field, have assembled authors to provide updates on the following topics: Evaluation and Management of Febrile Infants; Pediatric Emergency Medicine and Ultrasonography; The Patient-Centered Pediatric Emergency Department; Health Considerations of Refuge and Immigrant Children; Management of scoliosis; Health and Wellness for LGBTQ Youth; Sexually exploited children: recognizing and addressing; Movement disorders in children; Childhood trauma management in primary care; Feeding issues in young children; Physician Well-being and Burnout; New Molecular Methods for Diagnosing Infectious Diseases; Parental refusal: treatments, procedures and vaccines; Pediatric oncology in the ICU setting; Diaphragmatic hernia: Management and Outcomes; and Global Health and Pediatric Education: Opportunities and Challenges. Readers will come away with the clinical information that supplements their professional knowledge so they can make informed clinical decisions that improve patient outcomes.
Pre Emptive Medicine Public Health Aspects Of Developmental Origins Of Health And Disease
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Author : Fumihiro Sata
language : en
Publisher: Springer
Release Date : 2018-12-11
Pre Emptive Medicine Public Health Aspects Of Developmental Origins Of Health And Disease written by Fumihiro Sata and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-11 with Medical categories.
This book reviews public health activities such as awareness campaigns, health education, and strategies for health policy based on recent epidemiological studies that provide insights into epigenetic processes caused by environmental factors and developmental plasticity. It provides the latest concepts and findings on the public health aspects of Developmental Origins of Health and Disease (DOHaD) research regarding early prevention of non-communicable diseases (NCDs). Attention is especially paid to key issues, including strategies for the effective prevention of NCDs in developmental stages of life and younger generations rather than in adults and the elderly. Public Health Aspects in Developmental Origins of Health and Disease (DOHaD) is structured in two parts; the first focuses on general remarks reviewing specific recommendations, practical methods and protocols, and future goals regarding public health aspects, while the second presents brief profiles of individual cohorts and consortia studies. This collection will benefit both new and established researchers, as well as students in the fields of epidemiology, clinical medicine, nutrition, education, and public health who are seeking comprehensive information on DOHaD and preemptive medicine.
Progress And Challenges In Precision Medicine
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Author : Mukesh Verma
language : en
Publisher: Academic Press
Release Date : 2016-12-22
Progress And Challenges In Precision Medicine written by Mukesh Verma and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-22 with Medical categories.
Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development
Precision Personalized Pediatric Oncology And Immune Therapies Rather Customize Than Randomize
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Author : Irene Slavc
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-04
Precision Personalized Pediatric Oncology And Immune Therapies Rather Customize Than Randomize written by Irene Slavc and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-04 with categories.
Barriers To Personalized Medicine In Pediatrics
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Author : Laura Crimi
language : en
Publisher:
Release Date : 2015
Barriers To Personalized Medicine In Pediatrics written by Laura Crimi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
"Background: Primary brain tumours, specifically high-grade astrocytoma (HGA), are one of the leading causes of death from cancer in children under the age of 20. A novel laboratory derived pharmacogenomic (PGx) test has been developed and is well placed for use as a standard of care. The test is able diagnostically stratify the disease, it can readily identify whether or not a child is a carrier of a genetic mutation causing resistance to all available curative treatments. Knowledge of this mutation will move pediatric patients directly into palliative care; doing so will prevent the child from receiving harsh, ineffective treatments. Personalized medicine in pediatrics is often met with controversy; the practical and ethical barriers associated with this test must be explored prior to implementation. Objective: The purpose of the investigation was to evaluate relevant barriers associated with the use of the novel PGx test as a standard of care in clinical pediatric oncology. Methods: A mixed methods embedded design was used to explore the barriers perceived by the end users of the novel pharmacogenomic test; end users included healthcare professionals working in either pediatric palliative care or pediatric oncology. Deliberative stakeholder consultations were used to explore barriers associated with the test. Stakeholder deliberations are unique in that they promote a space for open discussion, with a goal of generating meaningful exchange and rich dialogue with informed stakeholders. The deliberations were followed by quantitative assessment using a tool aimed at evaluating the occurrence of deliberation and to measure the deliberation success. Consultations were recorded and a thematic analysis was conducted. Setting: The study took place at Montreal Children's Hospital in Montreal, Quebec. Participants: End users of the test, including: pediatric oncologists, pediatric palliative care physicians, pediatric palliative care nurses, pediatric oncology nurses, bioethicists and a social worker, were recruited as stakeholders to participate in the deliberations. Results: A better understanding of the barriers surrounding the use of this novel PGx test was attained. Relevant barriers to implementation identified by stakeholders included: the role of palliative care in patient management, communication, the impact of the test on care and the existence of conflicting cultures of care between pediatric oncology and palliative care. Several minor themes were also identified, including: the need for training to prevent the patient's experience of abandonment, difficulties with maintaining hope, providing inter-professional support and media as barrier. Results from the self-administered quantitative survey corroborated qualitative results showing that deliberation occurred; deliberative output was generated and it was concluded that a joint pre-clinic weekly meeting between pediatric oncology and pediatric palliative care would facilitate the introduction of this test as a standard of care. Conclusions: The study identified barriers that exist when implementing a pharmacogenomic test, capable of delivering a terminal diagnosis, as a standard of care in clinical pediatric oncology. It is hoped that this framework for exploring the implementation of a PGx test in clinical care can be generalized and used for other tests." --
Pediatric Critical Care Medicine
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Author : Derek S. Wheeler
language : en
Publisher: Springer Science & Business
Release Date : 2014-04-26
Pediatric Critical Care Medicine written by Derek S. Wheeler and has been published by Springer Science & Business this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-26 with Medical categories.
The second edition of Pediatric Critical Care Medicine spans three volumes, with major sections dedicated to specific organ systems. Each major section consists of separate chapters dedicated to reviewing the specific disease processes affecting each organ system. Each chapter concludes with a comprehensive list of references, with brief, concise remarks denoting references of ‘special interest’ and ‘of interest’. Consequently, the books are unique in their comprehensive coverage of pediatric critical care and their ease of use and will be of value to those studying towards pediatric critical care examinations and those who are already qualified.