Precision Medicine In Pediatrics
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Precision Medicine In Pediatrics
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Author : Jian Gao
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-22
Precision Medicine In Pediatrics written by Jian Gao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-22 with Science categories.
Precision Medicine In Pediatric Health
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Author : Olaf Bodamer
language : en
Publisher: Academic Press
Release Date : 2020-05-01
Precision Medicine In Pediatric Health written by Olaf Bodamer and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-01 with Science categories.
Precision Medicine in Pediatric Health is an invaluable resource on state-of-the-art tools, technologies and social and ethical issues involved in fully realizing precision medicine in new pediatric research and healthcare. The book adopts a holistic approach that is grounded in key learning points and practical case studies of interest to interdisciplinary teams of researchers and clinicians working in pediatrics. Chapters provide a thorough introduction to basic principles of precision medicine, its growing role in research and clinical care, relevant technologies and digital health. From there, the book examines best practices and offers support for implementing precision medicine in research and clinical settings. Chapters are devoted to varying specialties, such as prenatal and fetal health, oncology, cardiology, neurology, rare diseases, developmental disorders, and precision therapeutics, including small molecule and gene and cell-based therapies. These sections are followed by a close look at ethical, legal and social implications of precision medicine in pediatrics, patient perspectives and next steps in research and clinical translation. Presents succinct commentary and key learning points that support the translation of precision and genomic medicine Highlights the practical use of precision medicine in the management of pediatric patients Provides a comprehensive volume that is written and edited by leading researchers, clinicians and scientists
Precision Medicine In Neonates
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Author : Karel Allegaert
language : en
Publisher: Frontiers Media SA
Release Date : 2021-07-27
Precision Medicine In Neonates written by Karel Allegaert and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-27 with Medical categories.
Personalized Precision Medicine In Autism Spectrum Related Disorders
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Author : Lidia V. Gabis
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-15
Personalized Precision Medicine In Autism Spectrum Related Disorders written by Lidia V. Gabis and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-15 with Medical categories.
Precision Personalized Pediatric Oncology And Immune Therapies Rather Customize Than Randomize
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Author : Irene Slavc
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-04
Precision Personalized Pediatric Oncology And Immune Therapies Rather Customize Than Randomize written by Irene Slavc and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-04 with categories.
Precision Medicine For Investigators Practitioners And Providers
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Author : Joel Faintuch
language : en
Publisher: Academic Press
Release Date : 2019-11-16
Precision Medicine For Investigators Practitioners And Providers written by Joel Faintuch and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-16 with Science categories.
Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers Covers disease groups and ancillary information about techniques, resources and consequences Follows a structured blueprint, ensuring essential chapters items are not overlooked
Advances In Pediatrics 2019
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Author : Carol D. Berkowitz
language : en
Publisher: Elsevier Health Sciences
Release Date : 2019-06-23
Advances In Pediatrics 2019 written by Carol D. Berkowitz and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-23 with Medical categories.
Each year, Advances in Pediatrics focuses on providing current clinical information on important topics in pediatrics. Dr. Carol Berkowitz and her editorial board, comprised of top experts in the field, have assembled authors to provide updates on the following topics: Evaluation and Management of Febrile Infants; Pediatric Emergency Medicine and Ultrasonography; The Patient-Centered Pediatric Emergency Department; Health Considerations of Refuge and Immigrant Children; Management of scoliosis; Health and Wellness for LGBTQ Youth; Sexually exploited children: recognizing and addressing; Movement disorders in children; Childhood trauma management in primary care; Feeding issues in young children; Physician Well-being and Burnout; New Molecular Methods for Diagnosing Infectious Diseases; Parental refusal: treatments, procedures and vaccines; Pediatric oncology in the ICU setting; Diaphragmatic hernia: Management and Outcomes; and Global Health and Pediatric Education: Opportunities and Challenges. Readers will come away with the clinical information that supplements their professional knowledge so they can make informed clinical decisions that improve patient outcomes.
Recent Advances In Molecular And Translational Medicine Updates In Precision Medicine
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Author : Somchai Chutipongtanate
language : en
Publisher: Bentham Science Publishers
Release Date : 2021-12-13
Recent Advances In Molecular And Translational Medicine Updates In Precision Medicine written by Somchai Chutipongtanate and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-13 with Medical categories.
Precision medicine is a disruptive innovation with a fast-evolving pace in the healthcare ecosystem. Precision medicine enables precise diagnosis and targeted treatment by considering individual variability in the abnormalities of causative genes and molecular drivers behind biochemical mechanisms. A vast amount of data created by advanced omics technologies is a foundation of precision medicine’s success, and the implications of the findings from these technologies can potentially improve clinical outcomes. Recent Advances in Molecular and Translational Medicine: Updates in Precision Medicine presents essential information of molecular and translational research in precision medicine, with a specific focus on pediatrics. This book provides an accessible introduction to omics technologies, gives a detailed explanation of bioinformatics workflows to interpret high-throughput omics profiles for molecular diagnosis, and collects some of the cutting-edge research for precise therapeutics. Contributions to the book have been provided by experts in biomedical engineering and clinical practice, thus, bringing an informed perspective to the reader on each topic. The book is a valuable resource for postgraduate students, researchers, data scientists and clinicians interested in precision medicine, as well as researchers in the field of genetics and pediatrics who are interested in understanding the role of precision medicine in clinical practice.
Barriers To Personalized Medicine In Pediatrics
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Author : Laura Crimi
language : en
Publisher:
Release Date : 2015
Barriers To Personalized Medicine In Pediatrics written by Laura Crimi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
"Background: Primary brain tumours, specifically high-grade astrocytoma (HGA), are one of the leading causes of death from cancer in children under the age of 20. A novel laboratory derived pharmacogenomic (PGx) test has been developed and is well placed for use as a standard of care. The test is able diagnostically stratify the disease, it can readily identify whether or not a child is a carrier of a genetic mutation causing resistance to all available curative treatments. Knowledge of this mutation will move pediatric patients directly into palliative care; doing so will prevent the child from receiving harsh, ineffective treatments. Personalized medicine in pediatrics is often met with controversy; the practical and ethical barriers associated with this test must be explored prior to implementation. Objective: The purpose of the investigation was to evaluate relevant barriers associated with the use of the novel PGx test as a standard of care in clinical pediatric oncology. Methods: A mixed methods embedded design was used to explore the barriers perceived by the end users of the novel pharmacogenomic test; end users included healthcare professionals working in either pediatric palliative care or pediatric oncology. Deliberative stakeholder consultations were used to explore barriers associated with the test. Stakeholder deliberations are unique in that they promote a space for open discussion, with a goal of generating meaningful exchange and rich dialogue with informed stakeholders. The deliberations were followed by quantitative assessment using a tool aimed at evaluating the occurrence of deliberation and to measure the deliberation success. Consultations were recorded and a thematic analysis was conducted. Setting: The study took place at Montreal Children's Hospital in Montreal, Quebec. Participants: End users of the test, including: pediatric oncologists, pediatric palliative care physicians, pediatric palliative care nurses, pediatric oncology nurses, bioethicists and a social worker, were recruited as stakeholders to participate in the deliberations. Results: A better understanding of the barriers surrounding the use of this novel PGx test was attained. Relevant barriers to implementation identified by stakeholders included: the role of palliative care in patient management, communication, the impact of the test on care and the existence of conflicting cultures of care between pediatric oncology and palliative care. Several minor themes were also identified, including: the need for training to prevent the patient's experience of abandonment, difficulties with maintaining hope, providing inter-professional support and media as barrier. Results from the self-administered quantitative survey corroborated qualitative results showing that deliberation occurred; deliberative output was generated and it was concluded that a joint pre-clinic weekly meeting between pediatric oncology and pediatric palliative care would facilitate the introduction of this test as a standard of care. Conclusions: The study identified barriers that exist when implementing a pharmacogenomic test, capable of delivering a terminal diagnosis, as a standard of care in clinical pediatric oncology. It is hoped that this framework for exploring the implementation of a PGx test in clinical care can be generalized and used for other tests." --
Toward Precision Medicine
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2012-01-16
Toward Precision Medicine written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-16 with Medical categories.
Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.