Precision Medicine Recent Advances Current Challenges And Future Perspectives
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Precision Medicine Recent Advances Current Challenges And Future Perspectives
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Author : Oriana Awwad
language : en
Publisher: Frontiers Media SA
Release Date : 2024-06-18
Precision Medicine Recent Advances Current Challenges And Future Perspectives written by Oriana Awwad and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-18 with Science categories.
Personalized medicine (precision medicine) is an evolving field that comprises medical interventions tailored to individuals or groups of patients. It is designed to facilitate enhanced screening and earlier disease detection, more precise disease diagnosis, and improved treatment. Personalized medicine allows patients to receive specific therapies that work best for them aiming for more effective treatment, better outcomes, safer clinical managements and more efficient health systems.
Toward Precision Medicine
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2012-01-16
Toward Precision Medicine written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-16 with Medical categories.
Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.
Genomics Driven Drug Discovery Through Pharmacogenomics
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Author : Parikesit, Arli Aditya
language : en
Publisher: IGI Global
Release Date : 2024-12-13
Genomics Driven Drug Discovery Through Pharmacogenomics written by Parikesit, Arli Aditya and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-13 with Medical categories.
Genetic diseases and disorders are common factors in modern pharmacogenomics. The study of emerging factors in epigenomics are significant for effective drug discovery and formulation, as well as for balancing pharmacological and ethical factors in drug development. The goal of drug discovery is to recognize the new molecular formulations impactful in the treatment of genetic diseases. Further exploration of the move from preclinical drug research to the clinical stage may reveal critical transformations to provide effective medicinal products in the market. As precision medicine evolves, genomics-driven drug discovery may also improve patient outcomes while reducing the trial-and-error approach to prescribing medications, assisting with individualized, targeted healthcare. Genomics-Driven Drug Discovery Through Pharmacogenomics explores the integration of genomics into drug discovery and development in the pharmacogenomics field. It offers effective solutions to address challenges of personalized healthcare, ethical dilemmas, and technological considerations involved in drug discovery. This book covers topics such as medical technology, personalized medicine, and drug development, and is a useful resource for medical professionals, healthcare workers, computer engineers, scientists, pharmacologists, academicians, and researchers.
Evolution Of Translational Omics
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2012-09-13
Evolution Of Translational Omics written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-13 with Science categories.
Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
Rare Diseases
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Author : Mani T. Valarmathi
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-09-22
Rare Diseases written by Mani T. Valarmathi and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-22 with Medical categories.
A rare disease is any disease or condition that affects a small percentage of the population. Many rare conditions are life-threatening or chronically debilitating, and unfortunately do not have appropriate treatments, rendering them incurable. In recent years, there has been substantial development in the area of rare disease research and its clinical applications, for instance, rare disease biology and genomics, epidemiology and preventions, early detection and screening, and diagnosis and treatment. In this context, this book consolidates the recent advances in rare disease biology and therapeutics, covering a wide spectrum of interrelated topics, and disseminates this essential knowledge in a comprehensible way to a greater scientific and clinical audience as well as patients, caregivers, and drug and device manufacturers, especially to support rare disease product development. Chapters cover such diseases as Felty’s syndrome, Löfgren’s syndrome, mesothelioma, epidermolysis bullosa, and more. This book is a valuable resource not only for medical and allied health students but also for researchers, clinical and nurse geneticists, genetic counselors, and physician assistants.
Diagnostic Advances In Precision Medicine And Drug Development
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Author : Emmanuel Kwaku Ofori
language : en
Publisher: CRC Press
Release Date : 2025-06-18
Diagnostic Advances In Precision Medicine And Drug Development written by Emmanuel Kwaku Ofori and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-18 with Medical categories.
To arrive at the most appropriate decision regarding patient management, an essential step for medical practitioners is to determine a correct and accurate diagnosis of the patient’s condition. In recent years there have been significant technological efforts in chemistry, biochemistry, laboratory science, and biotechnology toward improving disease diagnosis and management in patients. Further, drug developers have utilized some of these novel diagnostic methods during preclinical and clinical trials that have led to creating efficiencies in their development processes. This book provides an overview of diagnostic procedures that aid in precision medicine and the drug development process. Presents innovative methodologies for diagnostic testing that will be beneficial to biomedical science researchers and health professionals Discusses recent significant technological advancement toward improving disease diagnosis Describes recent developments in spectroscopic and chromatographic methods that will be of interest to pharma companies and scientists in chemistry, biochemistry and pharmacology Gives an overview of the integration of artificial intelligence in digital health that will be beneficial to biotechnologists, bioengineers, health professionals and people in regulatory agencies Is suitable globally for graduate and postgraduate students studying laboratory medicine
Recent Advances In Molecular Targets For Drug Discovery And Delivery In Tumor
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Author : Sanjun Shi
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-05
Recent Advances In Molecular Targets For Drug Discovery And Delivery In Tumor written by Sanjun Shi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-05 with Science categories.
Precision Medicine And Human Health
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Author : Farzana Mahdi
language : en
Publisher: Bentham Science Publishers
Release Date : 2024-06-03
Precision Medicine And Human Health written by Farzana Mahdi and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-03 with Medical categories.
Precision Medicine and Human Health covers several aspects of precision medicine in 20 edited reviews by researchers and healthcare professionals. The breadth of information provided by the contributors aims to familiarize readers with basic and applied research in personalized therapy. Starting with an overview of the subject and its relationship with epigenetics, the book progresses into advanced topics that explain its wider applications. The use of precision medicine in treating different diseases such as protein misfolding disorders, gut ulcers and their effect on the gut microbiome, cancer treatment (for hepatocellular carcinoma, breast cancer, and oral cancer), fibromyalgia, high altitude sickness, and multiple sclerosis is explained. The book also covers modern therapeutic techniques to administer personalized therapy, including epithelial-mesenchymal therapy (EMT), circadian clock modulation, and artificial intelligence and phytoconstituents. The next chapters cover advanced technologies that are crucial to precision medicine, such as nanomaterials and advanced drug delivery systems. A concluding chapter on the therapeutic use of tannins in precision medicine rounds up the contents. Key Features: - Features 20 focused chapters contributed by scientific experts - Introduces readers to basic concepts in precision medicine - Covers the application of precision medicine in treating different diseases - Showcases several techniques used in experimental and clinical precision therapy - Explains modern technologies in precision medicine - Caters to a wide readership with introductions, structured headings, and references This is an informative reference for healthcare professionals in clinics and hospitals and any scholar who wants to learn about basic and applied knowledge in precision medicine.
Lab On A Chip Devices For Advanced Biomedicines
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Author : Arpana Parihar
language : en
Publisher: Royal Society of Chemistry
Release Date : 2024-08-14
Lab On A Chip Devices For Advanced Biomedicines written by Arpana Parihar and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-14 with Technology & Engineering categories.
The global miniature devices market is poised to surpass a valuation of $12–$15 billion USD by the year 2030. Lab-on-a-chip (LOC) devices are a vital component of this market. Comprising a network of microchannels, electrical circuits, sensors, and electrodes, LOC is a miniaturized integrated device platform used to streamline day-to-day laboratory functions, run cost-effective clinical analyses and curb the need for centralized instrumentation facilities in remote areas. Compact design, portability, ease of operation, low sample volume, short reaction time, and parallel investigation stand as the pivotal factors driving the widespread acceptance of LOC within the biomedical community. In this book, the Editors meticulously explore LOC through three key ‘Ts’: Theories (microfluidics, microarrays, instrumentation, software); Technologies (additive manufacturing, artificial intelligence, computational thinking, smart consumables, scale-up tactics, and biofouling); and Trends (biomedical analysis, point-of-care diagnostics, personalized healthcare, bioactive synthesis, disease diagnosis, and space applications) This comprehensive text not only provides readers with a thorough understanding of the current advancements in the LOC domain but also offers valuable insights to support the utilization of miniaturized devices for enhanced healthcare practices. Aimed at career researchers looking for instruction in the topic and newcomers to the area, the book is also useful for undergraduate and postgraduate students embarking on new studies or for those interested in reading about the LOC platform.
Smart Ways Of Biomaterial Designing Synthesis And Characterization
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Author : Arvind K. Singh Chandel
language : en
Publisher: CRC Press
Release Date : 2025-03-07
Smart Ways Of Biomaterial Designing Synthesis And Characterization written by Arvind K. Singh Chandel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-07 with Science categories.
This book explores the design, synthesis, and characterization of natural and synthetic polymeric biomaterials for diverse biomedical applications, including drug delivery, tissue engineering, and antimicrobial coatings. It highlights advances in polymer chemistry, offering insights into the modification of polymers’ properties to meet biomedical challenges. The book provides detailed strategies for material design and characterization, addressing practical issues faced by researchers. It also covers crucial aspects such as materials-tissue interaction, sterilization prior to in vivo use, and the characterization of biomaterials for development. Serving as a comprehensive guide for students, researchers, and professionals in the biomedical field, this book aims to bridge the gap between laboratory research and clinical applications.