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Predictive Modeling Of Human Microbiota And Their Role In Health And Disease


Predictive Modeling Of Human Microbiota And Their Role In Health And Disease
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Predictive Modeling Of Human Microbiota And Their Role In Health And Disease


Predictive Modeling Of Human Microbiota And Their Role In Health And Disease
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Author : Hyun-Seob Song
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-19

Predictive Modeling Of Human Microbiota And Their Role In Health And Disease written by Hyun-Seob Song and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-19 with Science categories.




The Human Microbiome Diet And Health


The Human Microbiome Diet And Health
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Author : Food Forum
language : en
Publisher: National Academies Press
Release Date : 2013-02-27

The Human Microbiome Diet And Health written by Food Forum and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-27 with Medical categories.


The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.



The Human Microbiota And Chronic Disease


The Human Microbiota And Chronic Disease
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Author : Luigi Nibali
language : en
Publisher: John Wiley & Sons
Release Date : 2016-08-05

The Human Microbiota And Chronic Disease written by Luigi Nibali and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-05 with Science categories.


Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin. A key methodology for exploring the microbiota, metagenomics, is also described. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis. Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity – periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major ‘idiopathic’ diseases afflicting humans, and the potential role that dysbiosis could play in their induction and chronicity. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces (faecal microbiota transplantation), and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position. Provides an introduction to dysbiosis, or a disruption in the composition of the normal human microbiota Explains how microbiota-associated pathology and other chronic diseases can result from changes in general bacterial composition Explores the relationship humans have with their microbiota, and its significance in human health and disease Covers host genetic variants and their role in the composition of human microbial biofilms, integral to the relationship between human health and human disease Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases.



Role Of Microbes In Human Health And Diseases


Role Of Microbes In Human Health And Diseases
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Author : Nar Singh Chauhan
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-06-05

Role Of Microbes In Human Health And Diseases written by Nar Singh Chauhan and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-05 with Medical categories.


Microbes are ubiquitous and have ecological interactions with almost all life forms. Likewise, humans invariably engage in host-microbial interactions that could induce short-term or long-term effects. Some of these long-term crossover interactions have allowed successful colonization of microbes within or on the human body, collectively known as the human microbiome or human microbiota. The human microbiome is identified as playing a key role in various physiological processes like digestion, immunity, defense, growth, and development. Any dysbiosis in the human microbiome structure could induce the onset of various metabolic or physiological disorders. Cumulatively, the human microbiome is considered as a virtual human organ that is essential for host survival. Additionally, short-term biological interactions of the host and microbes have exposed microbes to the human cellular system. This exposure could have allowed the microbes to invade human cells for their growth and reproduction-induced onset of various infectious diseases. This book incorporates a number of studies highlighting the role of microbes in human health and diseases.



Role Of Microbes In Sustainable Development


Role Of Microbes In Sustainable Development
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Author : R.C. Sobti
language : en
Publisher: Springer Nature
Release Date : 2024-01-20

Role Of Microbes In Sustainable Development written by R.C. Sobti and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-20 with Science categories.


This book examines the role of human microbiome in human health and diseases. The initial chapters present tools for genetic manipulation of gut microbiota and the therapeutic applications of engineered microbiota. They discuss the interaction between human microbiota and host in defining the prominent role of microbes in the development and progression of major human diseases. The book also summarizes the current applications and trends for the development, production and analytical characterization of recombinant therapeutic proteins in microbial systems. It also reviews the role of microbes in the production of vaccines and antibiotics. Further, the book presents bacterial products, including proteins, enzymes, immunotoxins and secondary metabolites, that target cancer cells and cause tumour regression. The chapters also discuss the critical role of gut microbiota dysbiosis in the pathogenesis of autoimmune disease and in bowel-related diseases. Towards the end, the book explores the role of intestinal microbiota in metabolic health and the pathogenesis of common metabolic disorders. It presents state-of-the-art insights into important aspects of United Nations—Sustainable Developmental Goal 3.



The Human Microbiome In Early Life


The Human Microbiome In Early Life
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Author : Omry Koren, PhD
language : en
Publisher: Academic Press
Release Date : 2020-10-02

The Human Microbiome In Early Life written by Omry Koren, PhD and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-02 with Science categories.


The Human Microbiome in Early Life: Implications to Health and Disease presents recent research advances that have highlighted the significance of early life, possibly beginning before birth, in the establishment of both the microbiome and its role in health and disease. The book reviews current knowledge on the origins of the human microbiota in early life, presents exposures which may disturb normal microbial colonization, and covers their implications to the risk of disease. Finally, emerging means to modify the early human microbiome to improve health are discussed. Examines the timeline of the human microbiome, from before conception to infancy, with an emphasis on clinical implications Evaluates the effort to understand not only the composition but also the origin of the microbiome Proves the emerging means to modify the human microbiome and particularly 'the first 1000 days of life' improve human health and prevent disease Generates resources to facilitate characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease



Microbiota In Health And Disease


Microbiota In Health And Disease
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Author : Pamela D. Browne
language : en
Publisher: Brill Wageningen Academic
Release Date : 2017

Microbiota In Health And Disease written by Pamela D. Browne and has been published by Brill Wageningen Academic this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Children categories.


This book offers a state-of-the-art overview of the vital relationship between human microbiota and infant and child health. Renowned clinical-experimental experts in this field discuss the development of microbiota during early life and review the environmental inputs that affect the developing infant's gut microbiota, such as early diet and (postnatal) medical interventions. They further describe the interplay between gut microbiota and functional systems of the body, from the immune system to the central nervous system. The book discusses a range of infant and childhood diseases that are associated with microbial changes or dysbiosis, such as gastrointestinal disorders, allergic diseases, autoimmune disorders and respiratory disorders. Additionally mechanisms by which microbial dysbiosis may influence behaviour in infants are discussed. Other topics include the use of current tools in molecular microbiology for microbiota-related research and clinical practice. In the management of particular paediatric disorders, the potential of microbial manipulation with pre- and probiotics during infancy and childhood is increasingly being investigated. This book presents the evidence supporting their use in practice and reviews safety aspects. Microbiota in health and disease: from pregnancy to childhood has the ambition to provide the reader with an overview of the most recent and stunning advances in the field of infant and child microbiota and their role in health, disease and prevention. As such, it is an excellent resource for health care professionals, students and researchers in the field of life sciences.



Microbiome In Human Health And Disease


Microbiome In Human Health And Disease
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Author : Pallaval Veera Bramhachari
language : en
Publisher: Springer Nature
Release Date : 2021-10-18

Microbiome In Human Health And Disease written by Pallaval Veera Bramhachari and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-18 with Medical categories.


The book provides an overview on how the microbiome contributes to human health and disease. The microbiome has also become a burgeoning field of research in medicine, agriculture & environment. The readers will obtain profound knowledge on the connection between intestinal microbiota and immune defense systems, medicine, agriculture & environment. The book may address several researchers, clinicians and scholars working in biomedicine, microbiology and immunology. The application of new technologies has no doubt revolutionized the research initiatives providing new insights into the dynamics of these complex microbial communities and their role in medicine, agriculture & environment shall be more emphasized. Drawing on broad range concepts of disciplines and model systems, this book primarily provides a conceptual framework for understanding these human-microbe, animal-microbe & plant-microbe, interactions while shedding critical light on the scientific challenges that lie ahead. Furthermore this book explains why microbiome research demands a creative and interdisciplinary thinking—the capacity to combine microbiology with human, animal and plant physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science.This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet in a typical immune system, and have contributed to animal and plant diversification over long evolutionary timescales. Also this book explains why microbiome research presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for human health and new strategies.



Microbiota


Microbiota
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Author : Takashi Matsumoto
language : en
Publisher:
Release Date : 2019

Microbiota written by Takashi Matsumoto and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Medical categories.


The human microbiota consists of a diverse collection of microbes including bacteria, archaea, viruses and eukaryotes. These organisms carry out a variety of functions that are vital to human health and well-being. One example is the prevention of bacterial infections by commensal bacterial in the gut. In recent years research has demonstrated a link between imbalances in the gut microbiota in early life and the development of obesity and allergic diseases in later life. The mechanisms of this and how diet, life-style factors and ageing influence the composition and activity of human microbiota are other areas of active research. The application of new technologies has revolutionised research initiatives providing new insights into the dynamics of these complex microbial communities and their role in health and disease. In this timely book expert international authors review selected hot-topics in this area to provide an up-to-date overview. Topics covered include: effect of ageing and diet; dysbiosis as an environmental factor; beneficial effects of probiotics on infants and children with dysbiosis; metaproteomics of the gut microbiota; gut microbiome and neuro development; the link between oral health and neurological disease; and the influence of the gut microbiome composition on GI tract cancer. The book is essential reading for everyone working with human microbiota, probiotics and prebiotics from the PhD student to the experienced scientist.



Microbiome In Human Health And Disease


Microbiome In Human Health And Disease
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Author : Pallaval Veera Bramhachari
language : en
Publisher:
Release Date : 2021

Microbiome In Human Health And Disease written by Pallaval Veera Bramhachari and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.


The book provides an overview on how the microbiome contributes to human health and disease. The microbiome has also become a burgeoning field of research in medicine, agriculture & environment. The readers will obtain profound knowledge on the connection between intestinal microbiota and immune defense systems, medicine, agriculture & environment. The book may address several researchers, clinicians and scholars working in biomedicine, microbiology and immunology. The application of new technologies has no doubt revolutionized the research initiatives providing new insights into the dynamics of these complex microbial communities and their role in medicine, agriculture & environment shall be more emphasized. Drawing on broad range concepts of disciplines and model systems, this book primarily provides a conceptual framework for understanding these human-microbe, animal-microbe & plant-microbe, interactions while shedding critical light on the scientific challenges that lie ahead. Furthermore this book explains why microbiome research demands a creative and interdisciplinary thinking-the capacity to combine microbiology with human, animal and plant physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science. This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet in a typical immune system, and have contributed to animal and plant diversification over long evolutionary timescales. Also this book explains why microbiome research presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for human health and new strategies.