Preparative Polar Organometallic Chemistry
DOWNLOAD
Download Preparative Polar Organometallic Chemistry PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Preparative Polar Organometallic Chemistry book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Preparative Polar Organometallic Chemistry
DOWNLOAD
Author : Lambert Brandsma
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Preparative Polar Organometallic Chemistry written by Lambert Brandsma and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Polar organometallic compounds are indispensable for the synthetic chemist. As this book shows, these almost ideal reagents are easy to prepare with high specificity under mild conditions and yet react quite readily with a great variety of substrates. Many compounds can be metallated directly at positions which would otherwise be difficult to substitute. Functional groups and heteroatoms already present in a molecule direct metallation to sites in their vicinity. The rules which govern polar organometallic chemistry often are not dominated by the usual n-delocalization and inductive effects; dipolar interactions, chelation, polarization, etc. often can be much more important. This affords novel synthetic opportunities. A good example is the development of a basically new type of aromatic substitution chemistry not based on positively charged intermediates. Seebach's injunction, "Thinking of polar organometallic compounds as carbanions is an impoverishment rather than a simplification" (International Symposium, Chemistry of Carbanions, Durham 1984), stresses the need to consider the metal not only as an integral, but perhaps also as the key component of these reagents. Rather than wandering off as solvated cations and acting as uninvolved spectators, the metals, rather than the anion moieties, can initiate and govern the subsequent reactions. To the founders of this field, e. g. Grignard, Ziegler, Gilman, Wittig, and their followers, the metal was critical. The title of Schlosser's book, "Polare Organometalle", certainly was apt.
Preparative Polar Organometallic Chemistry
DOWNLOAD
Author : Lambert Brandsma
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Preparative Polar Organometallic Chemistry written by Lambert Brandsma and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Preparative Polar Organometallic Chemistry is a collection of laboratory procedures for the synthesis and functionalization of organoalkali and Grignard compounds. The second volume with methods for generation and transformation of compounds bearing the metal at an sp3 carbon complements the first in which the metal was bound to an sp2 carbon atom in the reagent. Synthetically important intermediates such as metallated S,S-acetales, imines, nitriles, isonitriles and ketones are illustrated. All procedures have been worked out in full detail and tested in the author's own laboratory. Both books are intended to be practical bench-top laboratory manuals for working organic chemists, from the student to the advanced scientist.
Preparative Polar Organometallic Chemistry
DOWNLOAD
Author : Lambert Brandsma
language : en
Publisher:
Release Date : 1990
Preparative Polar Organometallic Chemistry written by Lambert Brandsma and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with categories.
Preparative Polar Organometallic Chemistry
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 1987
Preparative Polar Organometallic Chemistry written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Organometallic chemistry categories.
Preparative Polar Organometallic Chemistry
DOWNLOAD
Author : Lambert Brandsma
language : en
Publisher: Springer
Release Date : 2011-11-02
Preparative Polar Organometallic Chemistry written by Lambert Brandsma and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-02 with Science categories.
Houben Weyl Methods Of Organic Chemistry Vol E 19d 4th Edition Supplement
DOWNLOAD
Author : Michael Hanack
language : de
Publisher: Georg Thieme Verlag
Release Date : 2014-05-14
Houben Weyl Methods Of Organic Chemistry Vol E 19d 4th Edition Supplement written by Michael Hanack and has been published by Georg Thieme Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-14 with Science categories.
Houben-Weyl is the acclaimed reference series for preparative methods in organic chemistry, in which all methods are organized accor ding to the class of compound or functional group to be synthesized. The Houben-Weyl volumes contain 146 000 product-specific experi mental procedures, 580 000 structures, and 700 000 references. The preparative significance of the methods for all classes of compou nds is critically evaluated. The series includes data from as far back as the early 1800s to 2003. // The content of this e-book was originally published in 1993.
Heterocyclic Chemistry
DOWNLOAD
Author : John A. Joule
language : en
Publisher: John Wiley & Sons
Release Date : 2010-06-15
Heterocyclic Chemistry written by John A. Joule and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-15 with Science categories.
This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide. Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry. The fifth edition of Heterocyclic Chemistry maintains the principal objective of earlier editions – to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry. Fully updated and expanded to reflect important 21st century advances, the fifth edition of this classic text includes the following innovations: Extensive use of colour to highlight changes in structure and bonding during reactions Entirely new chapters on organometallic heterocyclic chemistry, heterocyclic natural products, especially in biochemical processes, and heterocycles in medicine New sections focusing on heterocyclic fluorine compounds, isotopically labeled heterocycles, and solid-phase chemistry, microwave heating and flow reactors in the heterocyclic context Essential teaching material in the early chapters is followed by short chapters throughout the text which capture the essence of heterocyclic reactivity in concise resumés suitable as introductions or summaries, for example for examination preparation. Detailed, systematic discussions cover the reactivity and synthesis of all the important heterocyclic systems. Original references and references to reviews are given throughout the text, vital for postgraduate teaching and for research scientists. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions available online), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.
Supramolecular Organometallic Chemistry
DOWNLOAD
Author : Ionel Haiduc
language : en
Publisher: John Wiley & Sons
Release Date : 2008-11-21
Supramolecular Organometallic Chemistry written by Ionel Haiduc and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-21 with Science categories.
Supramolecular chemistry has become not only a major field of chemistry, but is also a vivid interface between chemistry, biology, physics, and materials science. Although still a relatively young field, termini such as molecular recognition, host-guest chemistry, or self-assembly are now common knowledge even for chemistry students, and research has already been honored with a Nobel Prize. This first book on supramolecular organometallic chemistry combines two areas in chemistry that are experiencing the fastest developments. It provides a comprehensive review of various organometallic assemblies, arranged according to the types of intermolecular bonding. Details on the synthesis, structures, and properties of these compounds will be a valuable asset to the scientific community. The broad spectrum of assemblies containing main group element, transition metal, or f-element metal and a diverse range of ligands, held together by different bonding interactions make this a fascinating compilation. Illustrated extensively, this book is a very easily accessible, yet wide-ranging source of information.
Organomagnesium Methods In Organic Chemistry
DOWNLOAD
Author : Basil J. Wakefield
language : en
Publisher: Academic Press
Release Date : 1995-03-16
Organomagnesium Methods In Organic Chemistry written by Basil J. Wakefield and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-03-16 with Science categories.
The book opens with a general overview of the constitution and reactivity of organomagnesium compounds, followed by information on handling them and on their detection and estimation. Throughout, practical aspects aswell as principles are emphasized. The chapters on the synthesis of organomagnesium compounds cover the preparation of special forms of metallic magnesium and the reaction of magnesium with substrates such as dienes, as well as the traditional preparation of Grignard reagents. Preparations by metallation and metal-halogen exchanges are also included, as are newer methods such as hydromagnesiation of alkenes and alkynes. Systematic coverage is provided on synthetically useful reactions of organomagnesium compounds. Of fundamental importance in organic synthesis are carbon-carbon bond forming reactions; additions to carbon-carbon, carbon-nitrogen, carbon-oxygen, and carbon-sulfur multiple bonds; and nucleophilic substitution at carbon. The formation of carbon-heteroatom bonds in organic compounds is described, where the heteroatom is hydrogen, nitrogen, oxygen, sulfur, or halogen. Finally, the use of organomagnesium compounds in preparing other organometalloid and organometallic compounds is outlined. Representative experimental procedures are included throughout the book, and tables with references to well-described examples are provided. Presents a general overview of the constitution and reactivity of organomagnesium compounds Provides coverage on the detection and estimation of organomagnesium compounds Emphasizes practical aspects as well as principles Covers the preparation of special forms of metallic magnesium and the reaction of magnesium with substrates such as dienes Includes preparations by metallation and metal-halogen exchanges Reviews new preparation methods such as hydromagnesiation of alkenes and alkynes Outlines information on synthetically useful reactions of organomagnesium compounds Describes the formation of carbon-heteroatom bonds in organic compounds Addresses the use of organomagnesium compounds in preparing other organometalloid and organometallic compounds Includes representative procedures and tables with references to well-described examples
Preparative Acetylenic Chemistry
DOWNLOAD
Author : L. Brandsma
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Preparative Acetylenic Chemistry written by L. Brandsma and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
The first edition of Preparative Acetylenic Chemistry was published in 1971 as one of a series of laboratory manuals containing experimental procedures. The book was used extensively by students during practical courses and laboratory research work and enabled procedures to be carried out by persons with relatively limited bench experience. Discussions about their results have in many cases led to modified procedures or descriptions which have now been incorporated in this considerably revised and up-dated edition.The new book contains a collection of some 250 experimental procedures on a scale of at least 0.1 molar for the preparation of a wide variety of compounds with a triple bond. A number of procedures in the old edition have been omitted and replaced by others; the subdivision and titling of the chapters and experiments have been changed; and the indexes have been replaced by a type-compound-method index. Some new and attractive methods have been included, e.g. eliminations under phase-transfer conditions and couplings under the influence of zero-valent palladium compounds. In a number of cases, additional experiments have been described in order to give a more complete picture of the scope of the concerned methods.This collection is based on almost 30 years active bench experience by the author and all the procedures have been checked at least once in the author's laboratory. It will undoubtedly provide as much useful and practical assistance as did its predecessor.