Presenilins And Alzheimer S Disease
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Presenilins And Alzheimer S Disease
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Author : Steven G. Younkin
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Presenilins And Alzheimer S Disease written by Steven G. Younkin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The role of the familial Alzheimer's Disease genes called "presenilins" in causing neuronal cell death and Alzheimer-related pathology.
Characterization Of The Presenilin 1 Telencephalin Interaction And Implications For Alzheimer S Disease
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Author : Cary Esselens
language : en
Publisher: Leuven University Press
Release Date : 2005
Characterization Of The Presenilin 1 Telencephalin Interaction And Implications For Alzheimer S Disease written by Cary Esselens and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Alzheimer's disease categories.
Physiological Study Of Presenilins And Baces Two Proteases Involved In The Pathogenesis Of Alzheimer S Disease
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Author : Jos Tournoy
language : en
Publisher: Leuven University Press
Release Date : 2006
Physiological Study Of Presenilins And Baces Two Proteases Involved In The Pathogenesis Of Alzheimer S Disease written by Jos Tournoy and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Alzheimer's disease categories.
Alzheimer S Disease
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Author : Sangram S. Sisodia
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-02-16
Alzheimer S Disease written by Sangram S. Sisodia and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-16 with Medical categories.
This book examines every major aspect of Alzheimer disease at a time when there has been no scholarly research volume on the subject published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.
Structural And Functional Repercussions Of Loss Of Function And Clinical Mutants Of Presenilin
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Author : Omar Nyabi
language : en
Publisher: Leuven University Press
Release Date : 2005
Structural And Functional Repercussions Of Loss Of Function And Clinical Mutants Of Presenilin written by Omar Nyabi and has been published by Leuven University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Alzheimer's disease categories.
Alzheimer's disease is a major health problem. The disease is clinically characterized by the progressive mental decline of the patients and pathologically by the accumulation of amyloid plaques and tangles and neurodegenerative changes in the brain. The cause of the disease remains unclear but in some cases, genetic (missense) mutations in the Amyloid Precursor Protein (APP) and in the Presenilin genes (PS1 & PS2) are sufficient to initiate the whole disease cascade. All these mutations cause in essence an increase in the generation or a change of the characteristics of the AB peptide making it more prone to produce amyloid plaques. The AB peptide is generated from the APP protein and the question how Presenilin influences APP processing and AB production is the main topic of our work.
Two Antioxidant Proteins Tsa And Pag Interact With Presenilin And Are Candidate Genes For Alzheimer S Disease
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Author : Michael Francis Wangler
language : en
Publisher:
Release Date : 2001
Two Antioxidant Proteins Tsa And Pag Interact With Presenilin And Are Candidate Genes For Alzheimer S Disease written by Michael Francis Wangler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.
Molecular Biology Of Alzheimer S Disease
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Author : Christian Haass
language : en
Publisher: CRC Press
Release Date : 2003-09-02
Molecular Biology Of Alzheimer S Disease written by Christian Haass and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Science categories.
Highlighting the latest and the most timely aspects of Alzheimer's disease research, this text will enable scientists in related research fields, as well as physicians working with Alzheimer's disease patients, to obtain a quick and complete overview of the current state of the art in one of the most exciting fields in neuroscience research. Leading scientists have contributed articles focusing on key developments in this field. This includes an overview about the pathology, the genetics of familial Alzheimer's disease, proteolytic generation and aggregation of amyloid -peptide, presenilins, risk factors such as ApoE, and transgenic animal models. Some of the latest developments in Alzheimer's disease research, including the effect of presenilin knock outs on amyloid -peptide generation, are also included.
Alzheimer S Disease
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Author : J.D. Turner
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
Alzheimer S Disease written by J.D. Turner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Medical categories.
Alzheimer's Disease is a progressive neurodegenerative disorder of late life with devastating consequences for the afflicted and their carers and poses one of the major challenges to medical research. Until recently, little hope of effective therapies capable of slowing the disease process or preventing its occurrence was apparent. With recent advances in the genetics and molecular biology of the disease processes and the demonstration of the involvement of multiple aetiological factors, however, real chances are now appearing for the identification of preventive drugs. In this discussion, experts from disciplines ranging from molecular genetics to the clinic provide review and novel data concerning the aetiology of AD and the establishment of drugfinding screening methods.
The Role Of Presenilins In Neurodegeneration And Neuroinflammation
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Author : Eva Christina Schulte
language : en
Publisher:
Release Date : 2009
The Role Of Presenilins In Neurodegeneration And Neuroinflammation written by Eva Christina Schulte and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Cellular Peptidases In Immune Functions And Diseases 2
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Author : Jürgen Langner
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11
Cellular Peptidases In Immune Functions And Diseases 2 written by Jürgen Langner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.
Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work , which combines biochemical, immunological and clinical research reports with literary reviews of the field.