Primary And Metastatic Liver Tumors

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Primary And Metastatic Liver Tumors

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Author : Kenneth Cardona
language : en
Publisher: Springer
Release Date : 2018-10-01

Primary And Metastatic Liver Tumors written by Kenneth Cardona and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-01 with Medical categories.

The incidence of primary and metastatic liver tumors is rising and the therapeutic armamentarium for these tumors is expanding at a rapid pace. Surgery remains the primary treatment modality for these tumors. With improvements in our perioperative management and operative techniques a larger proportion of patients are able to undergo potentially curative liver surgery. In addition, indications and criteria for liver transplantation for both primary and metastatic liver tumors are constantly expanding. Unfortunately, many patients are not amendable to surgical resection or liver transplantation and therefore alternative liver-directed therapies are routinely being implemented as part of complex multidisciplinary treatment models. However, these models are continually evolving as these regional therapeutic options continue to expand. New embolization agents and techniques, as well as, improvements in radiation delivery, are all evolving in the background of improvement in systemic and targeted therapy options for these tumors. This book provides a comprehensive, state-of-the art review of the current state of liver-directed therapy for malignant liver tumors. The book will serve as a valuable resource for not only surgeons and clinicians but for researchers with an interest in malignant liver tumors. The book focuses on the therapeutic approach to primary and metastatic tumors providing an up-to-date review on surgical liver anatomy and new imaging techniques as well as patient selection and technical consideration for resection and transplantation. In addition, the book provides new insight into novel and evolving therapies in the areas of transarterial therapy such as: (i) bland embolization, (ii) chemoembolization, and (iii) radioembolization; as well as new radiation techniques including SBRT and proton therapy. Furthermore, the expanding role of hepatic artery infusion therapy in primary malignant tumors is highlighted. Finally, integration of all these regional therapy options with upcoming and evolving systemic and targeted therapy regimens are integrated and discussed. This book will serve as a very useful resource for clinicians and researchers managing and treating patients with these challenging malignancies. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.

Liver Directed Therapy For Primary And Metastatic Liver Tumors

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Author : Mark S. Talamonti
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17

Liver Directed Therapy For Primary And Metastatic Liver Tumors written by Mark S. Talamonti and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.

Liver-Directed Therapy for Primary and Metastatic Liver Tumors is a comprehensive examination of tumors of the liver. It provides a unique multi-modality approach to management of all types of primary and secondary liver tumors. The biology of liver cancers, state of the art radiologic imaging and novel, non-surgical interventional strategies are given. There is an in depth analysis of surgical options including transplantation, resection, interstitial ablation techniques and liver-directed chemotherapy for hepatocellular carcinoma, bile duct cancers, and colorectal and neuroendocrine liver metastases. Because of the unique and comprehensive examination of liver tumors, this work is an excellent resource for surgical, transplant and medical oncologists, surgeons, gastroenterologists, and radiologists.

Therapeutic Strategies In Primary And Metastatic Liver Cancer

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Author : Christian Herfarth
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Therapeutic Strategies In Primary And Metastatic Liver Cancer written by Christian Herfarth and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Primary and metastasizing malignant carcinoma of the liv er represent a challenge to both the diagnostician and the therapist. For this reason, it appears a worthwhile task to review the current status of knowledge about the treatment of primary and metastasizing tumors of the liver. The ques tion is whether modem diagnostic methods and new thera peutic concepts can help to improve the prospects of treat ment. Of particular interest is the role played by therapeu tic procedures directly involving the liver. Thus, it is equally important to discuss the pathophysiological and pharmacological bases for a modem therapy concept as it is to consider diagnostic issues and possible definitions of stages of progression. Therapeutic concepts comprise sys temic therapy and organ-related therapeutic methods, in cluding surgical resection, changes in the blood supply, re gional selective chemotherapy, and other localized or regional, highly specialized forms of therapy. This survey of the various possibilities in the field is meant too to stimulate further scientific research, given that methods of treatment are as yet by no means stan dardized, but are still in the stage of clinical research, where experimental models can find an application. The only well-established operative procedure is surgery on the isolated liver tumor. In this area, specialized techniques and various intraoperative procedures are discussed. There is a wealth of information available on all the top ics covered.

Liver Tumors

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Author : M.D., Ph.D., F.A.C.S., Alexander Julianov
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-02-03

Liver Tumors written by M.D., Ph.D., F.A.C.S., Alexander Julianov and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-03 with Medical categories.

This book is oriented towards clinicians and scientists in the field of the management of patients with liver tumors. As many unresolved problems regarding primary and metastatic liver cancer still await investigation, I hope this book can serve as a tiny step on a long way that we need to run on the battlefield of liver tumors.

Solid Liver Tumors

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Author : James Henry Foster
language : en
Publisher: W.B. Saunders Company
Release Date : 1977

Solid Liver Tumors written by James Henry Foster and has been published by W.B. Saunders Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Medical categories.

Tumors Of The Liver

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Author : G. T. Pack
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Tumors Of The Liver written by G. T. Pack and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

The surgical resection of a major portion of the liver for cancer of this viscus has long been neglected. Although the first successful resection of a primary malignant tumor of the liver was performed by LUCKE in 1891, this pioneer effort failed to stimulate interest in the operative removal of hepatic neoplasms. Earlier surgeons were intimidated by the concept of the liver as a huge vascular sponge possessed of three intricate circulatory systems. To the fear of uncontrollable hemorrhage was added the supposed hazard of hepatic insufficiency following the removal of a large portion of an organ with so many vital functions. Last but not least was the difficulty in surgical exposure. Only in recent years has the sporadic interest of surgeons been changed to a growing concern about the possibilities of extirpation of hepatic tumors by the per formance of major hepatic lobectomies. Four factors have contributed to this: 1) the dissemination of more accurate information about the surgical anatomy of the intrin sic and extrinsic hepatic circulatory systems, which has acquainted surgeons with the principles and techniques of hemostasis essential for successful operative intervention on the liver; 2) increased knowledge of the functions and regenerative capacity of the liver; 3) greater diagnostic skill aided by modern laboratory procedures; 4) improved surgical exposure of the liver by the use of laparothoracotomy incisions. Primary liver cancer varies widely in incidence in different parts of the world.

Liver Metastasis

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Author : Leonard Weiss
language : en
Publisher:
Release Date : 1982

Liver Metastasis written by Leonard Weiss and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medical categories.

Liver Metastasis

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Author : Cornelis Van de Velde
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Liver Metastasis written by Cornelis Van de Velde and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

B. CADY Hepatic met,,'~tasl~S present one of the major therapeutic challenges of cancer patien: management, for it is the destruction of vital organ function that makes cancer fatal, not local tumor growth. The process of tumor cell dislodgement from the primary cancer, their spread through the lymphatic and hematogenous channels, their lodgement in distant sites, and their subsequent progressive growth tax our comprehension a'ld i. -ustrate our therapies. The proceedings of this International Con,t ss on Hepatic Metastasis address these aspects of metastases to t:'. >2 _ . ver, and predominatly focus on metastatic colon cancer because of t ~. s frequency, its prominent hepatic only pattern of spread, and enticing preliminary data about prevention and control of small sub . '(ts of the afflicted population. Predictably, the "false technologies" of Dr. Lewis Thomas that involve surgical, radiotherapeutic and chemo therapeutic attack on these metastases after elaborate diagnostic studies take precedence because of the clinical imperatives of sick patients. This is displayed in the preponderance of papers and in terest in various diagnostic scanning techniques by means of radio isotopes, radiographically useful dyes, biochemical markers, interest in developing accurate staging systems to categorize patients for therapeutic comparisons, and interest in elaborate, and expensive, technology to increase the effectiveness of chemotherap~utic agents that are of limited benefit with simple intravenous administration. Behind this clinical enthusiasm, however, lies the research to develop the "true technology," in Thomas' words, that will prevent such clinical catastrophies as hepatic metastases.

Primary Liver Cancer In Japan

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Author : Takayoshi Tobe
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Primary Liver Cancer In Japan written by Takayoshi Tobe and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Hepatocellular carcinoma (HCC) is common in the Far East and South Africa, but is rare in the United States and Europe. The vast experience of the East, which has led to marked improvement in the prognosis of patients with HCC, is made available to researchers worldwide in this monograph. The book is based on an enormous amount of data that has been collected and analyzed by the Liver Cancer Study Group of Japan. The data stems from a survey on HCC in Japan since 1965 and contains information from more than 30,000 patients with regard to age distribution, past medical history, diagnostic procedures, frequency of HBV-associated antigens and antibodies, surgical and conservative treatments, gross anatomical and histological features of the tumors, pathology of the noncancerous portions, distant metastasis, and survival rate. This data is a tremendous contribution to our understanding of the epidemiology, pathology, and the latest developments of the molecular biology and clinical problems of primary liver cancer.

Noncolorectal Nonneuroendocrine Liver Metastases

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Author : Isidoro Di Carlo
language : en
Publisher: Springer
Release Date : 2014-11-25

Noncolorectal Nonneuroendocrine Liver Metastases written by Isidoro Di Carlo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-25 with Medical categories.

This book offers a complete overview on non colorectal non neuroendocrine (NCRNNE) liver metastases and describes in detail the currently available therapies. Each chapter focuses on the treatment of metastases from a particular primary malignancy and also provides valuable information on incidence, natural history and diagnosis. NCRNNE liver metastases are rare entities compared with colorectal and neuroendocrine metastases, for which the treatments are well codified. While more publications have appeared on the topic in recent years, an in-depth study has to date been lacking. Furthermore, most published series are insufficiently comparable as they comprise patients with NCRNNE hepatic metastases from a variety of primary malignancies and consequently overlook differences in tumor behavior, frequency of isolated hepatic metastases, response to neoadjuvant or adjuvant therapy and interval between diagnosis of the primary tumor and the liver metastases. This book, with its more specific approach, will serve not only as an up-to-date guide to diagnosis and treatment but also as a reference on which to base future studies.