Primary Biliary Cirrhosis
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Primary Biliary Cirrhosis
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Author : Keith D. Lindor
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Primary Biliary Cirrhosis written by Keith D. Lindor and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The condition of prolonged obstructive jaundice with patent bile ducts was first described in 1851 by Addison and Gull of Guy's Hospital, London. The term primary biliary cirrhosis (PBC) was defined in 1950 by Ahrens and colleagues of the Rockefeller Institute, New York. The condition was considered rare but this changed in 1965 with the discovery of a definitive diagnostic serum mitochondrial antibody test and the recognition that a raised serum alkaline phosphatase value, often discovered incidentally, could be a diagnostic pointer. If the diagnosis is made earlier, the end stages are rarely reached as death is replaced by liver transplantation. On November 6th 1997, in Chicago, an International Faculty discussed in depth the clinical features, pathogenesis and treatment of PBC, no longer considered a rare disease. The course of PBC is long, but some 18 years after the discovery of a positive mitochondrial antibody test in a symptom free patient with normal serum biochemistry, 83% will have developed abnormal tests and 76% will be symptomatic. Identification of those who will progress rapidly is difficult. The serum antimitochondrial profile may be useful but this is a very specialist technique. Mathematical prognostic models are useful in therapeutic trials and in the selection and timing of patients for liver transplantation but have limited value in individual patients. An increasing serum bilirubin level remains the most important indicator of rapid progression. Its value however can be negated by the use of ursodeoxycholic acid which has a bilirubin-lowering effect.
Primary Biliary Cholangitis An Issue Of Clinics In Liver Disease E Book
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Author : Elizabeth J Carey
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-07-13
Primary Biliary Cholangitis An Issue Of Clinics In Liver Disease E Book written by Elizabeth J Carey and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-13 with Medical categories.
The Guest Editors have put together an issue of clinical reviews that provides the most current look at PBC. Authors, all experts in their respective areas, have submitted articles in the following areas: Changes in epidemiology of PBC; Genetic and epigenetics in PBC; Role of bile acids and the bicarbonate umbrella in the pathogenesis of PBC; Current treatment options in PBC; Work in progress: Drugs in development; Natural history of PBC in the UDCA era: Role of scoring systems; Treatment of Pruritus: Tricks of the trade; Chronic complications of cholestasis: Work-up and Management; Individualizing care: Management beyond medical therapy; Role of liver biopsy: When to do, how to stage; AMA-negative PBC: Is it really the same as AMA-positive PBC?; New thoughts on Overlap syndrome with auto-immune hepatitis; and Current status of liver transplantation for PBC.
Primary Biliary Cirrhosis
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Author : E. Jenny Heathcote
language : en
Publisher:
Release Date : 2003
Primary Biliary Cirrhosis written by E. Jenny Heathcote and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
Primary Biliary Cholangitis An Issue Of Clinics In Liver Disease E Book
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Author : Binu V. John
language : en
Publisher: Elsevier Health Sciences
Release Date : 2022-10-21
Primary Biliary Cholangitis An Issue Of Clinics In Liver Disease E Book written by Binu V. John and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-21 with Medical categories.
In this issue of Clinics in Liver Disease, guest editor Dr. John V. Binu brings his considerable expertise to the topic of Primary Biliary Cholangitis. PBC leads to inflammation and scarring of the small bile ducts, and, if untreated, can lead to cirrhosis and liver failure. In this issue, top experts provide a state-of-the-art review of diagnosis and treatment for this chronic, progressive liver disorder. Contains 13 practice-oriented topics including genetics of primary biliary cholangitis; prognostic scoring systems in PBC; overlap syndromes and PBC; non-invasive evaluation of fibrosis and portal hypertension in PBC; treatment of PBC: first- and second-line therapies; novel therapies for PBC; and more. Provides in-depth clinical reviews on primary biliary cholangitis, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Primary Biliary Cirrhosis New Insights For The Healthcare Professional 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-10
Primary Biliary Cirrhosis New Insights For The Healthcare Professional 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-10 with Medical categories.
Primary Biliary Cirrhosis: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Primary Biliary Cirrhosis in a compact format. The editors have built Primary Biliary Cirrhosis: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Primary Biliary Cirrhosis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Primary Biliary Cirrhosis: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Primary Biliary Cirrhosis An Issue Of Clinics In Liver Disease
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Author : E. Jenny Heathcote
language : en
Publisher: Saunders
Release Date : 2008-05
Primary Biliary Cirrhosis An Issue Of Clinics In Liver Disease written by E. Jenny Heathcote and has been published by Saunders this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05 with Bile ducts categories.
Primary biliary cirrhosis (PBC) is a disease characterized by inflammatory destruction of the small bile ducts within the liver. PBC eventually leads to cirrhosis of the liver. The cause of PBC is unknown, but because of the presence of autoantibodies, it is generally thought to be an autoimmune disease. Other causes, such as infectious agents, have not been completely excluded. In this issue, the guest editor has expert authors present information on important topics such as epidemiology of PBC, pathogenesis of PBC, medical therapies, and liver transplantation in PBC.
Primary Biliary Cirrhosis
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Author :
language : en
Publisher:
Release Date : 1997
Primary Biliary Cirrhosis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with categories.
Primary Biliary Cirrhosis
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Author : James Neuberger
language : en
Publisher:
Release Date : 1999
Primary Biliary Cirrhosis written by James Neuberger and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Liver categories.
Biliary Disease
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Author : Gideon Hirschfield
language : en
Publisher: Springer
Release Date : 2017-02-24
Biliary Disease written by Gideon Hirschfield and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-24 with Medical categories.
This book addresses the current understanding of the diagnosis and management of biliary disease across all ages, with emphasis on how the latest advances in clinical science may be integrated into current and future therapies. The coverage is wide ranging, encompassing congenital and acquired conditions including cholestatic syndromes, biliary atresia, drug-induced cholestasis, primary biliary cholangitis/cirrhosis, primary sclerosing cholangitis, cholangiocarcinoma, gallstone disease, and autoimmune sclerosing cholangitis. With contributions from basic and clinical scientists, the relevance of state-of-the-art mechanistic biology to diagnosis, treatment, and future opportunities for drug design is clearly explained. The balance between science and clinical practice will ensure that this book makes a lasting contribution to the field. A broad readership will find the book easy to access and a rich source of information on current best practice and evolving management strategies.
Primary Sclerosing Cholangitis
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Author : Lisa M. Forman
language : en
Publisher: Springer
Release Date : 2016-11-12
Primary Sclerosing Cholangitis written by Lisa M. Forman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-12 with Medical categories.
This text provides a state-of-the art review of primary sclerosing cholangitis (PSC). The volume focuses on new data about risk factors for PSC, its natural history of the disease, and the epidemiology and genetics of PSC, while providing a comprehensive overview on current and future therapies for PSC, management of cholangiocarcinoma, and other hepatobiliary malignancies. It also touches upon up-to-date surgical and endoscopic management, including liver transplantation- both deceased donor and living related liver transplantation. Written by experts in the field, Primary Sclerosing Cholangitis: Current Understanding, Management, and Future Developments is a valuable resource for clinicians, surgeons and researchers with an interest in biliary liver disease, inflammatory bowel disease, and liver transplantation.