Principles Of Bone Biology
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Principles Of Bone Biology
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Author : John P. Bilezikian
language : en
Publisher: Academic Press
Release Date : 2019-08-22
Principles Of Bone Biology written by John P. Bilezikian and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-22 with Science categories.
Preface from the first edition (1996): "The world of modern science is undergoing a number of spectacular events that are redefining our understanding of ourselves. As with any revolution, we should take stock of where we have been, where we are, and where we are going. Our special world of bone biology is participating in and taking advantage of the larger global revolution in modern science... we assembled experts from all over the world and asked them to focus on the current state of knowledge and the prospects for new knowledge in their area of expertise. To this end, Principles of Bone Biology was conceived." - John P. Bilezikian, Lawrence G. Raisz, Gideon A. Rodan Praise for the previous edition: "Students, teachers, and practitioners will benefit from reading it, and investigators will use it as a reference work; it will certainly be consulted frequently." --The New England Journal of Medicine For over two decades, "Big Gray" has been the go-to repository of knowledge in the disciplines related to bone and mineral metabolism. The fourth edition is a must-have for students new to the field; young investigators at the graduate or postgraduate level beginning their research careers; established scientists who need to keep up with the changing nature of the field, looking to enrich their own research programs, or who are changing their career direction; clinicians who want ready access to up-to-date relevant basic science. This new edition builds on the successful formula from previous editions, taking the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics. Principles of Bone Biology, Fourth Edition provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. Bone research continues to generate enormous attention, due to the broad public health implications of osteoporosis and related bone disorders. This classic, fully updated, two volume reference is designed for anyone involved in the study of bone biology. Provides a "one-stop" shopping paradise. Anything you want to find about bone biology is here and written by the world’s experts THE essential resource for anyone involved in the study of the skeleton and metabolic bone diseases Covers everything from the basic scientific concepts to the underlying principles of therapeutics and management Allows readers to easily search and locate information quickly in the online format Volumes include: Basic Principles; Molecular Mechanisms of Metabolic Bone Disease; Pharmacological Mechanisms of Therapeutics; Methods in Bone Research
Principles Of Bone Biology
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Author : John P. Bilezikian
language : en
Publisher: Academic Press
Release Date : 2008-09-29
Principles Of Bone Biology written by John P. Bilezikian and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-29 with Medical categories.
Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field The essential resource for anyone involved in the study of bones and bone diseases Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics Readers can easily search and locate information quickly as it will be online with this new edition
Principles Of Bone Biology
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Author : John P. Bilezikian
language : en
Publisher:
Release Date : 2008
Principles Of Bone Biology written by John P. Bilezikian and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Bones categories.
Dynamics Of Bone And Cartilage Metabolism
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Author : Markus J. Seibel
language : en
Publisher: Elsevier
Release Date : 2006-07-24
Dynamics Of Bone And Cartilage Metabolism written by Markus J. Seibel and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-24 with Medical categories.
This updated edition is a comprehensive treatise that spans the complete range of basic biochemistry of bone and cartilage components to the clinical evaluation of disease markers in bone and joint disorders. With contributions from over 75 international experts, Dynamics of Bone and Cartilage Metabolism, Second Edition, is indispensable reading for those involved in skeletal research as well as for rheumatologists, endocrinologists, clinical biochemists, and other clinical disciplines participating in the management of patients with bone and cartilage diseases. Part I provides an up-to-date account of current knowledge of the structure, biosynthesis and molecular biology of the major tissue components Part II covers the organizational structure and cellular metabolism of bone and cartilage Part III deals with the utility of components specific to bone and cartilage as biomarkers of health and disease
Current Topics In Bone Biology
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Author : Hong-wen Deng
language : en
Publisher: World Scientific
Release Date : 2005-05-09
Current Topics In Bone Biology written by Hong-wen Deng and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-09 with Science categories.
This book covers a wide spectrum of areas related to basic bone research. While bone remodeling, bone development, and osteoclast biology constitute the main contents, topics important to the understanding of bone metabolism and treatment of bone-related diseases are also intensively reviewed. Three chapters are dedicated to the classic topic of bone mechanics, which include a brief overview of the mechanostat hypothesis, a more detailed review on mechanotransduction and bone adaptation, and a chapter illustrating the basic principles of bone mechanical testing. New emerging fields such as skeletal stem cells, bone tissue engineering, phytoestrogens applications, and bone genetics study using mouse models, are also covered in detail. The book closes with a special chapter dedicated to state-of-the-art advances in bone biology research.
Genetics Of Bone Biology And Skeletal Disease
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Author : Rajesh V. Thakker
language : en
Publisher: Academic Press
Release Date : 2017-10-31
Genetics Of Bone Biology And Skeletal Disease written by Rajesh V. Thakker and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-31 with Medical categories.
Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets. Identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluation of treatments Demonstrates how the interactions between bone and joint biology, physiology, and genetics have greatly enhanced the understanding of normal bone function as well as the molecular pathogenesis of metabolic bone disorders Summarizes the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder
Principles Of Bone Regeneration
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Author : Jona J. Sela
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-03-13
Principles Of Bone Regeneration written by Jona J. Sela and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-13 with Technology & Engineering categories.
Principles of Bone Regeneration is a timely publication that addresses the modern aspects of bone healing and repair. This exciting new volume details the convergence of the different experimental and clinical approaches designed for the study and treatment of bone healing in its diverse forms and under varying conditions. Bone healing is affected by a multitude of genetic, environmental, mechanical, cellular and endocrine variables which eventually lead to changes in gene expression that enhance the guided action of osteoblasts (and chondroblasts) to lay down bone that restores, or even improves, the skeletal load bearing capacity. Recent breakthroughs in understanding the regulatory aspects of bone formation and resorption, in both research and clinical arenas offer new modalities to induce, enhances and guide repair processes in bone for the benefit of millions of patients with conditions such as nonunion fractures, critical size defects, orthodontic tooth movement, periodontal bone loss, intraosseous implants and deformed bones.
Principles Of Osteoimmunology
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Author : Peter Pietschmann
language : en
Publisher: Springer
Release Date : 2016-08-18
Principles Of Osteoimmunology written by Peter Pietschmann and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-18 with Medical categories.
This fully updated and extended second edition provides a comprehensive overview on the basic concepts of the rapidly developing field of osteoimmunology and also offers in-depth insights into the molecular mechanisms of bone diseases. Clinical data is presented and put into context with the latest research findings. This second edition in addition discusses the latest topics in transplantation immunology. The book addresses scientists and physicians working in immunology, pathophysiology and osteology.
Translational Endocrinology Of Bone
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Author : Gerard Karsenty
language : en
Publisher: Academic Press
Release Date : 2012-12-31
Translational Endocrinology Of Bone written by Gerard Karsenty and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Medical categories.
The use of model organisms together with the power of genetics has profoundly affected our understanding of the physiology of one organ, the skeleton, in two distinct but complementary ways. This is the first translational reference to focus on these major conceptual advances in bone biology and their development in the clinic. Several advances have already been translated into therapies and others are being tested for diseases as different as osteoporosis, type-2 diabetes, and hypo-fertility. This book is a timely reference for both basic and clinical researchers in bone biology and endocrinology. Summarizes the latest research and translational applications of how the varied growth and development of bone affects appetite, metabolism, reproduction, and a wide range of endocrine functions Provides a common language for bone biologists, endocrinologists, osteologists, and other researchers, such as neuroscientists, who study appetite, fuel metabolism and diabetes, to discuss the development of translational research and new therapeutic strategies for bone, metabolic, and neuro-endocrine diseases. Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of bone research and therapeutics, as opposed to searching through thousands of journal articles
Principles Of Bone And Joint Research
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Author : Peter Pietschmann
language : en
Publisher: Springer
Release Date : 2017-09-07
Principles Of Bone And Joint Research written by Peter Pietschmann and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-07 with Medical categories.
This textbook discusses the basics and clinical aspects of bone research in an accessible way. It aims at enhancing students’ understanding of the structure, pathophysiology and regeneration of bone and associated connective tissues. The book covers a diverse aspects of this interdisciplinary field, including immunology, molecular biology and regenerative medicine, as well as tissue engineering and strategies that combine biomaterials, cells and growth-stimulating factors to trigger tissue development and regeneration. As such, the book offers an essential guide for advanced master’s students and PhD students in biomedicine, orthopedics and rheumatology.