Principles Of Computational Genomics
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Principles Of Computational Genomics
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Author : Paolo Provero
language : en
Publisher: CRC Press
Release Date : 2025-05-13
Principles Of Computational Genomics written by Paolo Provero and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-13 with Science categories.
The advent of high-throughput experimental assays, and in particular of next-generation sequencing, has revolutionized life sciences by enabling the generation of data at the scale of the whole genome. Extracting biologically useful or clinically actionable information from this data requires analytical methods quite different from the ones used to analyze low-throughput experimental results. The development of these methods is the goal of computational biology. Understanding the principles on which these methods are based is thus necessary for all students and researchers in life sciences. This book provides the conceptual framework needed to understand computational genomics enough to be able to follow the arguments in recent papers, or to collaborate with computational scientists in research projects. In particular, it introduces the mathematical and statistical basis of the methods in some depth. The main focus is on the analysis of next-generation-sequencing assays, both for the interpretation of the DNA sequence per se (sequence alignment, phylogenetic tree reconstruction, genetic variants) and for the study of gene regulation and epigenomics (gene expression, transcription factor binding, chromatin states, 3D structure of the genome). The final chapter discusses the associations of genetic variants with phenotypes and diseases, and their biological interpretation. Principles of Computational Genomics provides a solid foundation for understanding the many parts of computational genomics, including those not treated directly in the book. It will be of great benefit to students and researchers across the life sciences.
Principles Of Computational Genomics
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Author : PAOLO. PROVERO
language : en
Publisher:
Release Date : 2025-05-08
Principles Of Computational Genomics written by PAOLO. PROVERO and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-08 with Computers categories.
The main focus is on the analysis of next-generation-sequencing assays, both for the interpretation of the DNA sequence per se and for the study of gene regulation and epigenomics.
Ethics Computing And Genomics
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Author : Herman T. Tavani
language : en
Publisher: Jones & Bartlett Learning
Release Date : 2006
Ethics Computing And Genomics written by Herman T. Tavani and has been published by Jones & Bartlett Learning this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Business & Economics categories.
Comprised of eighteen chapters contributed by experts in the fields of biology, computer science, information technology, law, and philosophy, Ethics, Computing, and Genomics provides instructors with a flexible resource for undergraduate and graduate courses in an exciting new field of applied ethics: computational genomics. The chapters are organized in a way that takes the reader from a discussion of conceptual frameworks and methodological perspectives, including ethical theory, to an in-depth analysis of controversial issues involving privacy and confidentiality, information consent, and intellectual property. The volume concludes with some predictions about the future of computational genomics, including the role that nanotechnology will likely play as biotechnologies and information technologies continue to converge.
Principles Of Computational Biology And Genome Analysis
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Author : Daniel McGuire
language : en
Publisher:
Release Date : 2017-06-21
Principles Of Computational Biology And Genome Analysis written by Daniel McGuire and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-21 with Computers categories.
Genome analysis has changed the way biological and anthropological evolution has been perceived. Computational analysis of genetic data has made it possible for the creation of speculative models that can predict possible evolutionary patterns while taking into account natural biological phenomena such as aging, disease and degeneration of the body. This book on computational biology and genome analysis contributes to the fields of computational neuroscience and computational evolutionary biology. The various studies that are constantly contributing towards advancing technologies and evolution of this field are examined in detail in this text. It elucidates new techniques and their applications in a multidisciplinary approach. This book is a vital tool for all researching or studying computational biology and genome analysis as it gives incredible insights into emerging trends and concepts.
Principles And Practices Of Plant Genomics Volume 3
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Author : Chittaranjan Kole
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Principles And Practices Of Plant Genomics Volume 3 written by Chittaranjan Kole and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Science categories.
This book presents the basic and applied aspects of sequencing of genes and genomes and their implication in the fine-scale elucidation of the plant genomes. The third volume presents an overview on the advances of plant genomics made in the past century; deliberations on the genomics resources; concepts, tools, strategies, and achievements of
Computational Genome Analysis
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Author : Richard C. Deonier
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-12-27
Computational Genome Analysis written by Richard C. Deonier and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-27 with Computers categories.
This book presents the foundations of key problems in computational molecular biology and bioinformatics. It focuses on computational and statistical principles applied to genomes, and introduces the mathematics and statistics that are crucial for understanding these applications. The book features a free download of the R software statistics package and the text provides great crossover material that is interesting and accessible to students in biology, mathematics, statistics and computer science. More than 100 illustrations and diagrams reinforce concepts and present key results from the primary literature. Exercises are given at the end of chapters.
Computational Matter
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Author : Susan Stepney
language : en
Publisher: Springer
Release Date : 2018-07-20
Computational Matter written by Susan Stepney and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-20 with Computers categories.
This book is concerned with computing in materio: that is, unconventional computing performed by directly harnessing the physical properties of materials. It offers an overview of the field, covering four main areas of interest: theory, practice, applications and implications. Each chapter synthesizes current understanding by deliberately bringing together researchers across a collection of related research projects. The book is useful for graduate students, researchers in the field, and the general scientific reader who is interested in inherently interdisciplinary research at the intersections of computer science, biology, chemistry, physics, engineering and mathematics.
Dictionary Of Scientific Principles
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Author : Stephen Marvin
language : en
Publisher: John Wiley & Sons
Release Date : 2012-11-27
Dictionary Of Scientific Principles written by Stephen Marvin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-27 with Science categories.
Dictionary of Scientific Principles presents a unique and timeless collection of (almost) all known rules or laws commonly called principles, identified throughout the history of scientific development, their definition, and use. Exploring a broad range of disciplines, the book first lists more than 2,000 principles organized in a standard alphabetical order, then provides a list of subject headings for which related principles are identified. A staple addition to every library, the dictionary will also be of interest to scientists and general readers.
Artificial Intelligence Technologies For Computational Biology
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Author : Ranjeet Kumar Rout
language : en
Publisher: CRC Press
Release Date : 2022-11-10
Artificial Intelligence Technologies For Computational Biology written by Ranjeet Kumar Rout and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-10 with Technology & Engineering categories.
This text emphasizes the importance of artificial intelligence techniques in the field of biological computation. It also discusses fundamental principles that can be applied beyond bio-inspired computing. It comprehensively covers important topics including data integration, data mining, machine learning, genetic algorithms, evolutionary computation, evolved neural networks, nature-inspired algorithms, and protein structure alignment. The text covers the application of evolutionary computations for fractal visualization of sequence data, artificial intelligence, and automatic image interpretation in modern biological systems. The text is primarily written for graduate students and academic researchers in areas of electrical engineering, electronics engineering, computer engineering, and computational biology. This book: • Covers algorithms in the fields of artificial intelligence, and machine learning useful in biological data analysis. • Discusses comprehensively artificial intelligence and automatic image interpretation in modern biological systems. • Presents the application of evolutionary computations for fractal visualization of sequence data. • Explores the use of genetic algorithms for pair-wise and multiple sequence alignments. • Examines the roles of efficient computational techniques in biology.
Advances In Bioinformatics
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Author : Vijai Singh
language : en
Publisher: Springer Nature
Release Date : 2021-07-31
Advances In Bioinformatics written by Vijai Singh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-31 with Science categories.
This book presents the latest developments in bioinformatics, highlighting the importance of bioinformatics in genomics, transcriptomics, metabolism and cheminformatics analysis, as well as in drug discovery and development. It covers tools, data mining and analysis, protein analysis, computational vaccine, and drug design. Covering cheminformatics, computational evolutionary biology and the role of next-generation sequencing and neural network analysis, it also discusses the use of bioinformatics tools in the development of precision medicine. This book offers a valuable source of information for not only beginners in bioinformatics, but also for students, researchers, scientists, clinicians, practitioners, policymakers, and stakeholders who are interested in harnessing the potential of bioinformatics in many areas.