Probiotic Trigger Molecules In Action
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Probiotic Trigger Molecules In Action
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Author : Jasna Novak (maiden Beganovic)
language : en
Publisher: Frontiers Media SA
Release Date : 2021-09-23
Probiotic Trigger Molecules In Action written by Jasna Novak (maiden Beganovic) and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-23 with Science categories.
Probiotic Bacteria And Enteric Infections
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Author : J.J. Malago
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-01-20
Probiotic Bacteria And Enteric Infections written by J.J. Malago and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-20 with Medical categories.
Every day many people suffer from intestinal diseases. These disorders can result from pathogens like bacteria, fungi, parasites and viruses, but the causes of non-infectious intestinal disorders and colorectal cancers remain to be elucidated. Disturbances to the normal gut flora (the microbiota) are central to the development of many, if not all, of these disorders. Disturbed gut microbiota is a prelude to public health issues like traveller’s-, antibiotic- and Clostridium difficile-associated diarrhoea, irritable bowel syndrome, inflammatory bowel disease, and colorectal cancers. This book discusses the way intestinal disorders affect the microbiota, how the disturbed microbiotal balance leads to enteric disorders and the ways to prevent these disorders. Further his book explores the potential of probiotics (live microorganisms that when ingested bring a health benefit) in treating enteric disorders by analysing the probiotic genome through proteomics, metabolomics and functional assays. Discussed is how the ingestion of specific microorganisms repairs the disturbed microbiota and subsequently ameliorates enteric disorders. Finally this book addresses how genetic engineering and biotechnology will contribute to the development of effective and safe designer probiotics.
Targeted Innovative Immunomodulation Of Allergy And Inflammation By Natural Molecules And Probiotics
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Author : Xiu-Min Li
language : en
Publisher: Frontiers Media SA
Release Date : 2025-03-03
Targeted Innovative Immunomodulation Of Allergy And Inflammation By Natural Molecules And Probiotics written by Xiu-Min Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-03 with Medical categories.
Allergy is described as a “global pandemic of non-communicable inflammatory disease”. The World Allergy Organization estimates that 10-40% of the world's population is affected by allergic diseases. Allergy manifests where the body confronts allergens in the environment such as nose or eyes, resulting in allergic rhinitis; skin resulting in dermatitis; airways resulting in asthma; and digestive system resulting in food allergy and eosinophilic esophagitis etc. Food allergy (FA) increased drastically in the past 2 decades. For example, the estimated prevalence of food allergy is 10 % in the US, 10-20% in UK, 25% in Australia. It estimates 200-400 million people may have food allergy globally. Other allergic conditions also significantly increased. These allergic conditions negatively affect quality of life in affected individuals and are potentially life threatening such as food-induced anaphylactic shock and uncontrolled asthma. Immunoglobulin E (IgE) is the central to the pathology of allergic diseases. IgE binds to mast cells and basophils via high affinity receptors. When these cells encounter specific allergens, surface bound IgE is crosslinked and this triggers the cells to degranulate and release mediators such as histamine, PAF and leukotrienes that cause symptoms such as hives, swelling, abdominal pain, itching and respiratory distress, and anaphylactic shock. Eosinophils are the major inflammatory cells that involved in variety of allergic inflammatory conditions. The mechanisms underlying the trend of allergy is largely unknown. Current approaches to manage allergy include avoiding triggers, using immune-suppressing corticosteroids, other medications such as antihistamine, and allergen immunotherapy. However, long term use of some of the drugs may spark resistance and undesirable adverse effects. There are no “cures” on the horizon. Innovative approaches are needed. Normally, IgE-producing B cells and plasma cells are minor populations with minimal IgE output, compared with their counterparts such as IgG and IgA. Dysregulation of these cells causes excessive and persistent IgE production, which is the key for allergy becoming lifelong. Despite decades of awareness about the centrality of allergen-specific IgE in allergy, inhibiting IgE production by B cells/plasma cells remains a major challenge. Omalizumab, the anti-IgE antibody, “traps” IgE temporarily but does not tackle IgE production. Oral immunotherapy (OIT), including Palforzia®, may paradoxically increase IgE levels.8-13 Therefore, further research should focus on how to restore normality of IgE immune regulation, which will alter the process of allergy leading to curative therapy. Recent research demonstrated that in addition to the classical Th1 and Th2 paradigm, B cell chemokines (CXCL13) and plasma transcription factors (XBP1 and Blimp1) contribute to persistent IgE production and to IgG1 cell conversion to IgE cells. BCL6 has been demonstrated as an IgE transcriptional suppressor. Furthermore, in addition Th2 cell, LC2 may also contribute to eosinophilic inflammation.
Medicinal Plants Microbial Interactions Molecular Techniques And Therapeutic Trends
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Author : Zulqurnain Khan, Azra Yasmin, Naila Safdar
language : en
Publisher: Bentham Science Publishers
Release Date : 2023-12-22
Medicinal Plants Microbial Interactions Molecular Techniques And Therapeutic Trends written by Zulqurnain Khan, Azra Yasmin, Naila Safdar and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-22 with Science categories.
Medicinal Plants: Microbial Interactions, Molecular Techniques, and Therapeutic Trends is a comprehensive exploration of the fascinating world of medicinal plants, their therapeutic advancements, and the application of molecular techniques to unlock their full potential. This book is structured into three illuminating sections, each shedding light on different facets of this rapidly developing field. Section 1: Exploring Plant-Microbe Interactions Covers the relationship between microbes and plants, the historical context and the pivotal role of microbes in shaping the future of medicinal plants. Discover the diverse array of bacteria associated with these plants and grasp their significance in enhancing the medicinal value of plants. Section 2: Harnessing Molecular Techniques Covers cutting-edge molecular techniques such as genome editing and modern breeding methods to optimize the genetic traits of medicinal plants. By understanding these techniques, readers will learn how to enhance plant growth, yield and quality. Section 3: Nanotechnology for Therapeutic Enhancement Covers nanotechnology and its transformative impact on medicinal plants. The section highlights emerging nano-engineering technology that can revolutionize the therapeutic properties of these plants. Medicinal Plants: Microbial Interactions, Molecular Techniques, and Therapeutic Trends is a book for Interdisciplinary readers: students, scientists, academics, and industry professionals alike. Whether you're a student, scientist, academic, or industry professional, this book is your gateway to the evolving world of plant-based medicine. Readership Students, scientists, academics, and industry professionals in plant sciences and pharmaceutical chemistry
Probiotics And Its Effects On Inflammatory And Infectious Disorders
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Author : Helioswilton Sales-Campos
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-28
Probiotics And Its Effects On Inflammatory And Infectious Disorders written by Helioswilton Sales-Campos and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-28 with Science categories.
Probiotics In The Prevention And Management Of Human Diseases
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Author : Mitesh Kumar Dwivedi
language : en
Publisher: Academic Press
Release Date : 2021-12-02
Probiotics In The Prevention And Management Of Human Diseases written by Mitesh Kumar Dwivedi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-02 with Technology & Engineering categories.
Probiotics in The Prevention and Management of Human Diseases: A Scientific Perspective addresses the use of probiotics and their mechanistic aspects in diverse human diseases. In particular, the mechanistic aspects of how these probiotics are involved in mitigating disease symptoms (novel approaches and immune-mechanisms induced by Probiotics), clinical trials of certain probiotics, and animal model studies will be presented through this book. In addition, the book covers the role of probiotics in prevention and management aspects of crucial human diseases, including multidrug resistant infections, hospital acquired infections, allergic conditions, autoimmune diseases, metabolic disorders, gastrointestinal diseases, neurological disorders, and cancers. Finally, the book addresses the use of probiotics as vaccine adjuvants and as a solution for nutritional health problems and describes the challenges of using probiotics in management of human disease conditions as well as their biosafety concerns. Intended for nutrition researchers, microbiologists, physiologists, and researchers in related disciplines as well as students studying these topics require a resource that addresses the specific role of probiotics in the prevention and management of human disease. - Contains information on the use of probiotics in significant human diseases, including antibiotic resistant microbial infections - Presents novel applications of probiotics, including their use in vaccine adjuvants and concept of pharmabiotics - Includes case studies and human clinical trials for probiotics in diverse disease conditions and explores the role of probiotics in mitigation of the symptoms of disease
Beyond Probiotics Dietary Microbial Modulators Of The Immune System Effects And Mechanisms
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Author : Margarida Castell
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-25
Beyond Probiotics Dietary Microbial Modulators Of The Immune System Effects And Mechanisms written by Margarida Castell and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-25 with Medical categories.
Probiotics And Prebiotics In Human Nutrition And Health
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Author : Venketeshwer Rao
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-07-13
Probiotics And Prebiotics In Human Nutrition And Health written by Venketeshwer Rao and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-13 with Medical categories.
Probiotic microorganisms are recognised as being beneficial for human health. Prebiotics are substrates that are used preferentially by the probiotic bacteria for their growth. A great deal of interest has been generated in recent years in identifying probiotic bacteria and prebiotics, their characterization, mechanisms of action and their role in the prevention and management of human health disorders. Together they are referred to as synbiotic. This book is in response to the need for more current and global scope of probiotics and prebiotics. It contains chapters written by internationally recognized authors. The book has been planned to meet the needs of the researchers, health professionals, government regulatory agencies and industries. This book will serve as a standard reference book in this important and fast-growing area of probiotics and prebiotics in human nutrition and health.
Probiotics For Human Nutrition In Health And Disease
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Author : Evandro Leite de Souza
language : en
Publisher: Academic Press
Release Date : 2022-06-15
Probiotics For Human Nutrition In Health And Disease written by Evandro Leite de Souza and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-15 with Technology & Engineering categories.
Probiotics for Human Nutrition in Health and Disease provides a comprehensive resource of information on traditional and emerging health concepts and the development and application evolution of probiotics and their role in prevention and treatment of human metabolic disorders and illnesses. Key issues related to the general aspects of probiotics, probiotics in human nutrition, and probiotics in human health promotion and disease treatment are described and discussed. Sections discuss general features of probiotics, such as relationships with prebiotics, probiotics in human nutrition, including pregnancy, lactation, in children, and in the elderly, and the role of probiotics in human health and disease treatment. This book provides the most significant knowledge, mechanistic bases, uses, clinical perceptions, case studies and perspectives about probiotics for humans, considering possibilities and limitations in light of the appropriate available reference materials. Written by highly qualified researchers and edited by a team of experts, each chapter summarizes the latest available information on probiotics in human health and critically interprets the most significant evidence by applying the author's own practical experience from investigations with probiotics. - Present traditional and emerging concepts, developments and the evolution of probiotics - Provides key insights that characterize probiotics as promising and innovative options for human nutrition - Discusses how probiotics can be used in a perspective of health promotion and prevention and treatment of human metabolic disorders and illnesses
Interactive Probiotics
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Author : Enrica Pessione
language : en
Publisher: CRC Press
Release Date : 2014-02-06
Interactive Probiotics written by Enrica Pessione and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-06 with Medical categories.
This book underlines the importance of reciprocal interactions between probiotics and humans in terms of stress induction, epigenetic control of cellular responses, oxidative status, bioactive molecules biosynthesis, moonlighting proteins secretion, endogenous toxins neutralization, and several other biological functions. It explores how these resp