Proceedings Of The International Beilstein Symposium On Glyco Bioinformatics
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Proceedings Of The International Beilstein Symposium On Glyco Bioinformatics
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Author : Martin G. Hicks
language : en
Publisher:
Release Date : 2011-02-13
Proceedings Of The International Beilstein Symposium On Glyco Bioinformatics written by Martin G. Hicks and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-02-13 with Glycomics categories.
The Beilstein Symposia address contemporary issues in the chemical and related sciences by employing an interdisciplinary approach. Scientists from a wide range of areas - often outside chemistry - are invited to present aspects of their work for discussion with the aim of not only advancing science, but also, furthering interdisciplinary communication. In 2009, the Beilstein-Institut in cooperation with Professor Peter Seeberger, MPI for Colloids and Surfaces (Potsdam), hosted the First Symposium on Glyco-Bioinformatics in Potsdam with the aim to pave the way towards the development of first ideas for the integration of glyco-bioinformatics in an universal platform that will serve biologist, chemists and all interested in glycosciences. Glycomics is an emerging field within the -omics-sciences which addresses the investigation of the structure-function relationships of complex biosynthesized carbohydrates and the role they play within biological systems. The post-genomic era has seen an explosion of activities in the areas of genomics and proteomics in both fundamental research as well as biotechnology applications. Sequencing and synthesis of nucleic acids and proteins has been performed in an automated fashion for many years now; these important basic techniques are now being applied to carbohydrates. Through the work of a number of key laboratories around the world, significant scientific and technical advances are being made resulting in an increasing number of data sets of important interactions of carbohydrates with proteins and nucleic acids become available. The scientific progress of both genomics and proteomics relies on the interdisciplinary nature of a laboratory-based and a computer-based cooperation. Such an interdisciplinary glyco-based community is currently starting to become established; this symposium is aimed at supporting these efforts by bringing together glycochemists and biologists with experts in bioinformatics and computer sciences to lay the ground-work for a concerted effort in the area of glyco-bioinformatics. The symposium covered the use of publicly available data, data mining, structure prediction and docking of carbohydrates, web-based services to combine proteomics and glycomics data for structure-function research and glycosylation analysis. In this Proceedings book ten authors contributed to a comprehensive view on the developments in the emerging field of glyco-bioinformatics.
Transforming Glycoscience
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2012-11-23
Transforming Glycoscience written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-23 with Science categories.
A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans-also known as carbohydrates, saccharides, or simply as sugars-play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields.
Healthgrid Applications And Technologies Meet Science Gateways For Life Sciences
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Author : Sandra Gesing
language : en
Publisher: IOS Press
Release Date : 2012
Healthgrid Applications And Technologies Meet Science Gateways For Life Sciences written by Sandra Gesing and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
Glyco Bioinformatics
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Author : Martin G. Hicks
language : en
Publisher:
Release Date : 2012
Glyco Bioinformatics written by Martin G. Hicks and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Bioinformatics categories.
Over the past decade, the scientific community of post-proteomics and post-genomics witnessed the rapid evolution of a new scientific field - the glycomics. The investigation of both glycans and glycan-binding proteins and lipids revealed increasingly the role of complex carbohydrates in diverse inter- and intracellular processes. Advances in analytical technologies, carbohydrate chemistry and structural biology led to an increased understanding of the high degree of variability of both composition, structure and function of sugars. Additionally, structure-function studies showed an inherent complexity which is determined by different branching patterns, various possible linkage positions and numerous building blocks. Even though there has been significant progress in the development of interdisciplinary approaches such as experimental and computer scientific tools, the general technological developments in glycomics lag behind those in the proteomic and genomic areas. In particular, despite the current progress in glyco-bioinformatics regarding the computational characterization of carbohydrates, the glycomics community is still lacking a systematic and comprehensive database and analysis software. The database landscape is made up of numerous independent and disconnected databases with partially overlapping core areas. These databases provide neither complete nor compatible data sets on glycan structures. Additionally, since the individual data encoding and analysis software tools do not use a common language for the representation of schematic structures and sequence topologies, data processing and interpretation become extremely challenging. The underlying aim of this symposium is to bring together glycochemists and biologists with experts in bioinformatics and computer sciences to pave the way for a concerted effort in the area of glyco-bioinformatics. Scientists who "produce" data met those who "use" the data. They discussed aspects such as data mining, structure prediction and docking of carbohydrates, as well as web-based services to combine proteomics and glycomics data for structure-function research and glycosylation analysis. This meeting continued successfully the efforts resulting from the first symposium held in October 2009 to discuss the necessity of a uniform data reporting practice that supports biologists, chemists and all interested in glycosciences to enable the integration of their experimental and analysis data into glyco-bioinformatics platforms.
Discovering The Subtleties Of Sugars
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Author : Martin G. Hicks
language : en
Publisher:
Release Date : 2015
Discovering The Subtleties Of Sugars written by Martin G. Hicks and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Bioinformatics categories.
The Beilstein Symposia address contemporary issues in the chemical and related sciences by employing and interdisciplinary approach. Scientists from a wide range of areas are invited to present aspects of their work for discussion, with the aim of not only advancing sciences, but also enhancing interdisciplinary communication. Traditionally, the Beilstein Symposia are kept small with up to 50 participants to provide a convivial atmosphere for the both lectures and lively discussions and the ready exchange of thoughts and ideas. The appreciation and understanding of the role that carbohydrates play in nature has grown over the last few years driven by the advances in our ability to analyze and synthesize their structures. Their role not only as primary energy-storage molecules but also as structural modifiers of e.g. glycoproteins and glycolipids, as well as in physiological and pathological events such as adherence, cell-cell interaction, transport, signaling and protection is becoming clearer and more accessible to researchers. Over the last decade the fields of glycobiology and glycochemistry in combination with in-silico applications have been augmented by a further field - glycomics. A major aim of glycomics research is to achieve a comprehensive identification and characterization of the repertoire of glycan structures present in an organism, cell or tissue at a defined time. The continual improvement of analysis methods and computational techniques leads to glycan characterization and identification with increased depth, speed and efficiency but also generates ever increasing amounts of data of variable quality and completeness. Thus the many web-accessible repositories result in a highly fragmented knowledgebase which in consequence complicates the development and application of bioinformatics tools for the analysis of this data. This situation has led to a general consensus that community wide efforts should be spent towards consolidating and systematizing the collective knowledgebase with integration of universal bioinformatics tools for both the representation, mining as well as annotation of experimental data sets to advance and interface glycomics with related genomics and proteomics projects. Additionally, both experimentalists and bioinformaticians also expressed their demands for data reporting practices that include the comprehensive description of conditions, techniques and experimental results to enable researchers to evaluate the degree of structural definitions, to interpret the results and to reproduce the experiments. This 3rd Beilstein Glyco-Bioinformatics Symposium brought together those scientists that produce data with those that use the data and make it available to the community. In particular, in their presentations speakers delivered insights into the diverse physiological and structural subtleties of sugars by covering aspects such as: structure-function relationships of carbohydrates, modeling carbohydrate structure and carbohydrate interactions with other biomacromolecules, deciphering carbohydrate signals, carbohydrate identification, annotation and analysis, metadata for the description of glycomics experiments, software tools for data mining and analysis.
Proceedings Of The Second International Conference On Bioinformatics Of Genome Regulation And Structure
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Author : International Conference on Bioinformatics of Genome Regulation and Structure 2, 2000, Novosibirsk
language : en
Publisher:
Release Date : 2000
Proceedings Of The Second International Conference On Bioinformatics Of Genome Regulation And Structure written by International Conference on Bioinformatics of Genome Regulation and Structure 2, 2000, Novosibirsk and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.
Peko Coup 400 Mit Stahlschutzrahmen Auf David Brown Schlepper Selectamatic 1200
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Author :
language : en
Publisher:
Release Date : 1973
Peko Coup 400 Mit Stahlschutzrahmen Auf David Brown Schlepper Selectamatic 1200 written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1973 with categories.
Proceedings Of 3rd Glycobiology World Congress 2017
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Author : ConferenceSeries
language : en
Publisher: ConferenceSeries
Release Date :
Proceedings Of 3rd Glycobiology World Congress 2017 written by ConferenceSeries and has been published by ConferenceSeries this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
June 26-28, 2017 London, UK Key Topics : Glycoprotein Technologies, Glyco Bioinformatics, Glycans in Drug Design, Glyco Immunology, Glyco Biomarkers, Glycobiology and Biotechnology, Glycans in Diseases and Therapeutics, Glycobiology in Personalized Medicine, Glycans in Genetic Disorders, Glycobiology and Structural Biology, Glyco Proteomics, Glycomics and Metabolomics, Mass Spectrometry in Proteome Research, Glycobiology, Genomics and Computational Systems Biology, Glycobiochemistry,
Proceedings Of The Second International Conference On Bioinformatics Of Genome Regulation And Structure
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Author : International Conference on Bioinformatics of Genome Regulation and Structure 2, 2000, Novosibirsk
language : en
Publisher:
Release Date : 2000
Proceedings Of The Second International Conference On Bioinformatics Of Genome Regulation And Structure written by International Conference on Bioinformatics of Genome Regulation and Structure 2, 2000, Novosibirsk and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.
Proceedings Of The Third International Conference On Bioinformatics Of Genome Regulation And Structure
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Author : International Conference on Bioinformatics of Genome Regulation and Structure 3, 2002, Novosibirsk
language : en
Publisher:
Release Date : 2002
Proceedings Of The Third International Conference On Bioinformatics Of Genome Regulation And Structure written by International Conference on Bioinformatics of Genome Regulation and Structure 3, 2002, Novosibirsk and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.