Progetto C M V Xy

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Progetto C M V Xy

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Author : Donato Bleve
language : it
Publisher: Booksprint
Release Date : 2017-09-30

Progetto C M V Xy written by Donato Bleve and has been published by Booksprint this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-30 with Fiction categories.

Appassionante romanzo che narra le vicende di due uomini che si ritrovano senza un lavoro a causa della crisi economica. I due, per volere di una regia superiore, saranno destinati a incontrarsi a Gerusalemme, laddove Lorenzo lavorerà in una équipe di archeologi destinati a una eccezionale scoperta e Christian sarà, appunto, l’“eccezionale scoperta”. L’autore riesce, con un linguaggio semplice e privo di orpelli, a farci entrare in questa miracolosa avventura: dapprima impariamo a conoscere Lorenzo e Christian, i loro sacrifici, le loro speranze e la loro tranquillità rovinati e resi inutili dal licenziamento, subito dopo accompagniamo i due, nelle loro vite parallele in epoche diverse, che porteranno alla nascita di colui che può salvare il mondo. Il lettore si lascerà sorprendere dai continui colpi di scena che movimentano la trama fino alla fine del testo.

Progetto C M V Xy

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Author : Donato Bleve
language : it
Publisher:
Release Date : 2017

Progetto C M V Xy written by Donato Bleve and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Fiction categories.

Crossroads Between Innate And Adaptive Immunity Iv

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Author : Peter D. Katsikis
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-01

Crossroads Between Innate And Adaptive Immunity Iv written by Peter D. Katsikis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-01 with Medical categories.

This volume presents a collection of reviews derived from work presented at the Aegean Conference: “4th Crossroads between innate and adaptive immunity”. This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The importance of the crosstalk between innate immunity and the adaptive immune response has only recently started to be appreciated. Although it is well recognized that dendritic cells, NK cells, NK-T cells and T cells are all critical for the host response to pathogens, the respective fields that study the biology of these immune cells tend to exist in parallel worlds with minimum exchange of information and ideas. This fragmentation hinders the integration of these fields towards a unified theory of host response. The Aegean Conference “Crossroads between Innate and Adaptive Immunity” brought together leading international scientists and experts to address critical areas of Innate and Adaptive immunity something necessary for the development of more efficient scientific exchange and crosspollination between these fields. This conference attracted scientists from all over the world to discuss their latest findings on the various aspects of Innate and Adaptive immunity. The conference had limited participation and a scientific and social program that maximized scientific interchange through lecture presentations, poster sessions and informal discussions. ​

Targeting The Broadly Pathogenic Kynurenine Pathway

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Author : Sandeep Mittal
language : en
Publisher: Springer
Release Date : 2015-11-18

Targeting The Broadly Pathogenic Kynurenine Pathway written by Sandeep Mittal and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-18 with Science categories.

Tryptophan metabolism via kynurenine pathway plays a critical role in both health and a variety of human diseases. This book highlights the known associations between kynurenine pathway and various disease states, as well as examines the current status of drug development and clinical trials of compounds known to alter tryptophan metabolism. The research plays a critical role in molecular targeted therapies directed at altering the kynurenine pathway of tryptophan metabolism. The initial and rate-limiting step of tryptophan metabolism is mediated by one of two enzymes, tryptophan-2,3-dioxygenase (TDO; predominantly in the liver, but also in the brain) and indoleamine-2,3-dioxygenase (IDO; in a host of tissues in response to immune activation). Targeting the enzymes IDO and TDO, as well as other downstream effectors would therefore be likely to generate novel treatment options that would be helpful in a wide variety of clinical settings. This book provides a unique bridge between basic mechanistic understanding of the role of the kynurenine pathway with translational applications and clinical relevance. It will explore the indications that tryptophan metabolism is a potential biomarker of disease activity, can contribute to local and possibly systemic immune suppression in cancer, and is an attractive target for which a variety of inhibitors are readily available.

Micrornas And The Immune System

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Author : Silvia Monticelli
language : en
Publisher: Humana
Release Date : 2016-08-23

Micrornas And The Immune System written by Silvia Monticelli and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Medical categories.

In recent years, the critical role of microRNAs has been revealed within the biology of cells that constitute the immune system. In MicroRNAs and the Immune System: Methods and Protocols, expert researchers explore the latest techniques for studying miRNA expression, including the most up-to-date data on splinted ligation and qRT-PCR assays, as well as high-throughput profiling through cloning, deep sequencing, and microarrays. Chapters outline methods to study miRNA functions in various cell types from a single cell type level to entire model organisms, and present studies of miRNAs in the context of viruses and the immune response. Tools are also provided to help navigate bioinformatics databases on miRNAs and their targets. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Contemporary and innovative, MicroRNAs and the Immune System: Methods and Protocols is an essential handbook for immunologists, biochemists, and molecular biologists.

Basal Cell Carcinoma

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Author : Michael R. Migden
language : en
Publisher: Springer Nature
Release Date : 2019-12-17

Basal Cell Carcinoma written by Michael R. Migden and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-17 with Medical categories.

​Basal Cell Carcinoma: Advances in Treatment and Research provides a comprehensive overview of evidence-based treatment approaches for the most common cancer worldwide - basal cell carcinoma. The first part of this book details the epidemiology, risk factors, pathophysiology, and different histologic subtypes of basal cell carcinoma highlighted with high-resolution histopathology images. The second part of the book provides an in-depth review of different treatment modalities including topical therapy, local immunotherapy with interferon, cryotherapy, electrodesiccation and curettage, radiotherapy, and surgical approaches with Mohs micrographic surgery, head and neck surgery, and oculoplastic surgery. The final part of book highlights the utilization of innovative technology such as photodynamic therapy and laser for the treatment of basal cell carcinoma while providing excellent cosmetic outcome as well as emerging systemic therapeutic options utilizing hedgehog pathway inhibitors and immunotherapy for the difficult-to-treat disease state, advanced basal cell carcinoma. Meant for a multi-disciplinary audience of dermatologists, Mohs Surgeons, oncologists, head and neck surgeons, oculoplastic surgeons, radiation oncologists, this book serves as an informative practical guide for physicians, mid-level providers and trainees.​ Basal Cell Carcinoma, is edited and written by leaders with expertise in cutaneous oncology, pathology, dermatology, Mohs micrographic surgery, plastic surgery, and many more specialties.

Cell Migration In Inflammation And Immunity

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Author : Daniele D’Ambrosio
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02

Cell Migration In Inflammation And Immunity written by Daniele D’Ambrosio and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.

Chemokines and their receptors play a central role in the pathogenesis of numerous, perhaps all, acute and chronic inflammatory diseases. About 50 distinct chemokines produced by a variety cell types and tissues either c- stitutively or in response to inflammatory stimuli are involved in a plethora of biological processes. These small secreted proteins exert their exquisitely variegated functions upon binding to a family of seven-transmembrane spanning G-protein coupled receptors (GPCRs) composed of almost 20 distinct entities. The biological activities of chemokines range from the control of leukocyte trafficking in basal and inflammatory conditions to the regulation of hema- poiesis, angiogenesis, tissue architecture, and organogenesis. The basis for such diversified activities rests, on one hand, upon the ubiquitous nature of chemokine production and chemokine receptor expression. Virtually every cell type can produce chemokines and expresses a unique combination of chemokine receptors. On the other hand, chemokine receptors make use of a flexible and complex network of intracellular signaling machineries that can regulate a variety of cellular functions ranging from cell migration, growth, and differentiation to death. As knowledge of the size of chemokine and chemokine receptor families rapidly reaches completeness, much is still to be uncovered in terms of fu- tional architecture of the chemokine system. The disparity between the large number of chemokines and that smaller number of receptors is balanced by the promiscuity in ligand–receptor interactions, with multiple chemokines binding to the same receptor and several chemokines binding to more than one receptor.

Matthews Plant Virology

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Author : Richard Ellis Ford Matthews
language : en
Publisher: Gulf Professional Publishing
Release Date : 2002

Matthews Plant Virology written by Richard Ellis Ford Matthews and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Plant diseases categories.

It has been ten years since the publication of the third edition of this seminal text on plant virology, during which there has been an explosion of conceptual and factual advances. The fourth edition updates and revises many details of the previous editon, while retaining the important older results that constitute the field's conceptual foundation. Key features of the fourth edition include: * Thumbnail sketches of each genera and family groups * Genome maps of all genera for which they are known * Genetic engineered resistance strategies for virus disease control * Latest understanding of virus interactions with plants, including gene silencing * Interactions between viruses and insect, fungal, and nematode vectors * New plate section containing over 50 full-color illustrations.

The Sustainability Of Agro Food And Natural Resource Systems In The Mediterranean Basin

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Author : Antonella Vastola
language : en
Publisher: Springer
Release Date : 2015-04-24

The Sustainability Of Agro Food And Natural Resource Systems In The Mediterranean Basin written by Antonella Vastola and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-24 with Technology & Engineering categories.

This book is focused on the challenges to implement sustainability in diverse contexts such as agribusiness, natural resource systems and new technologies. The experiences made by the researchers of the School of Agricultural, Forestry, Food and Environmental Science (SAFE) of the University of Basilicata offer a wide and multidisciplinary approach to the identification and testing of different solutions tailored to the economic, social and environmental characteristics of the region and the surrounding areas. Basilicata’s productive system is mainly based on activities related to the agricultural sector and exploitation of natural resources but it has seen, in recent years, an industrial development driven by the discovery of oil fields. SAFE research took up the challenge posed by market competition to create value through the sustainable use of renewable and non-renewable resources of the territory. Moreover, due to its unique geographical position in the middle of the Mediterranean basin, Basilicata is an excellent “open sky” laboratory for testing sustainable solutions adaptable to other Mediterranean areas. This collection of multidisciplinary case studies and research experiences from SAFE researchers and their scientific partners is a stimulating contribution to the debate on the development of sustainable techniques, methods and applications for the Mediterranean regions.

Molecular Biology Of Hematopoiesis Proceedings

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Author : Nader G. Abraham
language : en
Publisher: S Karger Ag
Release Date : 1996

Molecular Biology Of Hematopoiesis Proceedings written by Nader G. Abraham and has been published by S Karger Ag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.

Revealing the mechanisms responsible for normal and abnormal cell proliferation and differentiation, and presenting innovative approaches for blood and bone marrow transplantation, this publication is recommended reading for all oncologists and hematologists.