Programmed Cell Death And Cardiovascular Disease
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Programmed Cell Death And Cardiovascular Disease
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Author : Zhi Qi
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-12
Programmed Cell Death And Cardiovascular Disease written by Zhi Qi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-12 with Science categories.
Apoptosis In Cardiac Biology
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Author : Heribert Schunkert
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-06-30
Apoptosis In Cardiac Biology written by Heribert Schunkert and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-30 with Medical categories.
Apoptosis or programmed cell death is increasingly considered to be a major factor in the development and progression of cardiovascular disease. In patients with heart failure the activation of apoptosis may result in the loss of irreplaceable cardiac myocytes promoting the clinical course of the syndrome. Moreover, in the coronary arteries inflammation and apoptosis may weaken critical structures of the vessel wall leading to plaque rupture and, subsequently, to myocardial infarction. Given these deleterious consequences, it seems almost paradoxical that programmed cell death is an active process that, if initiated under physiological circumstances, is essential for both coordinated tissue growth or destruction of malignant cells. Apoptosis in Cardiac Biology, written by a team of internationally renowned researchers, gives a timely synopsis of basic mechanisms, cellular and structural targets and, finally, clinical implications of programmed cell death in the heart. The expert authors of this volume give concise overviews on general and cell-specific aspects of programmed cell death in cardiac myocytes and fibroblasts, as well as in vascular smooth muscle and endothelial cells. Furthermore, novel therapeutic options arising from the outstanding pathophysiological significance of cardiac apoptosis are presented. This comprehensive review of Apoptosis in Cardiac Biology will be of interest to both clinicians and basic researchers who are active in the fields of cardiology and atherosclerosis.
Programmed Cell Death
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Author : Mark Paul Mattson
language : en
Publisher:
Release Date : 2001
Programmed Cell Death written by Mark Paul Mattson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Apoptosis categories.
This volume provides the most recent insight into how abnormalities in the regulation of cell death lead to a variety of diseases. Each chapter in this book is written by an internationally recognized expert on the role of aberrant cell death in the pathogenesis of a particular disease. In addition to various types of cancer and neurodegenerative disorders, this book covers diseases ranging from arthritis to cardiovascular disease to diabetes. The chapters each integrate information obtained from patients with data obtained in experimental models of the disease to arrive at an emerging view of the pathogenic mechanisms of the disease. Applications of this fundamental knowledge to prevention and treatment of the diseases are considered. When taken together with http://www.elsevier.nl/locate/isbn/0444504931Programmed Cell Death, Volume 1, this title will provide graduate students, postdocs and senior investigators in an array of biomedical disciplines invaluable resource for their pursuit of the causes and cures of many different human diseases.
Cytokines Novel Cell Death Models And Pathways In Cardiovascular Diseases
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Author : Yuli Huang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-26
Cytokines Novel Cell Death Models And Pathways In Cardiovascular Diseases written by Yuli Huang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-26 with Medical categories.
Cytokines are soluble proteins secreted by a wide variety of cells in the body, playing crucial roles in many physiological responses and are involved in the pathophysiology of cardiovascular diseases (CVDs). Recently, there is great progress in discoveries that some novel cytokines, including secreted frizzled-related proteins (SFRPs), adiponectin, and C1q/TNF-Related Proteins (CTRPs), can perform a protective effect in cardiometabolic diseases, heart failure and coronary heart disease. However, the mechanisms underlying the molecular and pathophysiological actions of these cytokines in CVDs are still vague. Novel mechanisms of cell death including pyroptosis, autophagy, ferroptosis, cuproptosis, and PANoptosis have been considered novel therapeutic targets for CVDs. Some cytokines have been shown to regulate the cell death pathway in the incidence and development of CVDs. Further investigations are needed to understand the link between these novel cytokines and novel cell death models and pathways in CVDs.
Apoptosis Involvement Of Oxidative Stress And Intracellular Ca2 Homeostasis
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Author : Gines Maria Salido
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-03-08
Apoptosis Involvement Of Oxidative Stress And Intracellular Ca2 Homeostasis written by Gines Maria Salido and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-08 with Medical categories.
Apoptosis: Involvement of Oxidative Stress and Intracellular Ca2+ Homeostasis, presents a concise synthesis of the current knowledge and recent advances in the mechanisms of apoptosis in different cells and the role of oxidative stress and Ca2+ signalling. Particular attention is given to the different features of apoptosis in distinct cell types, ranging from hepatocytes to cardiovascular and blood cells, nervous cells or spermatozoa. Cutting-edge and user-friendly, this volume serves as a comprehensive resource for those interested in the fascinating biological processes associated to programmed cell death or apoptosis. The book is divided in two major chapter sections: general mechanisms of the apoptotic pathways and the role of oxidative stress and intracellular Ca2+ homeostasis and a more specific section dedicated to the specificities of apoptosis in a number of excitable and non-excitable cells. All of the contributions are from specialists in the field and the reviews presented, systemically examine the most exciting and innovative aspects of the apoptotic pathways in their particular areas of expertise.
Apoptosis Genes
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Author : James W. Wilson
language : en
Publisher: Springer
Release Date : 2012-12-16
Apoptosis Genes written by James W. Wilson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-16 with Science categories.
This useful work presents a current overview of key genes involved in the control of apoptosis research together with thoughts on future prospects and clinical applications. While there are several books written on apoptosis, this one deals specifically with its regulation.
Cardiac Hypertrophy And Failure
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Author : Bernard Swynghedauw
language : en
Publisher:
Release Date : 1990
Cardiac Hypertrophy And Failure written by Bernard Swynghedauw and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medical categories.
Cardiac insufficiency, a major cause of premature mortality, is a key focus of medical and pharmaceutical research. This book aims to bring clinicians and researchers up-to-date on recent biophysical, cellular physiological and molecular biological developments and their clinical applications.
Programmed Cell Death
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Author : Yun Bo Shi
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Programmed Cell Death written by Yun Bo Shi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
This volume contains papers that were presented and discussed at The 1996 Interna tional Symposium on Programmed Cell Death, which was held in the Shanghai Science Center of the Chinese Academy of Sciences on September 8-12, 1996. Apoptosis has attracted great attention in the past several years. This is reflected in part by the exponential increase in the number of papers published on the subject. While several major scientific conferences have been held in recent years, this meeting repre sents the first major international scientific meeting on programmed cell death held in Asia, where fast economic growth promises a bright future for both basic and applied re search in biomedical sciences. We organized the meeting with the belief that such a gath ering would foster a closer interaction between scientists from the West and those in Asia. Research on programmed cell death has expanded so extensively that no one meet ing can cover all the important subjects related to apoptosis. The Shanghai meeting fo cused on several key areas ranging from well-established ones, such as cell death in the immune system, to emerging ones, such as the role ofECM in regUlating cell fate. Specifi cally, the subjects presented and discussed included programmed cell death during devel opment, the regulation and biochemical mechanisms of lymphocyte apoptosis, the involvement of extracellular matrix and its remodeling in programmed cell death, genes that cause or prevent cell death, and the application of apoptosis toward cancer therapy.
Programmed Cell Death Apoptosis
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Author : David J. McConkey
language : en
Publisher:
Release Date : 1995-01-01
Programmed Cell Death Apoptosis written by David J. McConkey and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-01-01 with categories.
Molecular Mechanisms Of Programmed Cell Death
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Author : Yufang Shi
language : en
Publisher: Springer
Release Date : 2013-03-11
Molecular Mechanisms Of Programmed Cell Death written by Yufang Shi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-11 with Medical categories.
The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner, H. Robert Horvitz, and John E. Sulston for their seminal discoveries concerning "genetic regulation of organ development and programmed cell death." This clearly marked the prime importance of understanding the molecular mechanisms controlling cell death. The 1 st International Symposium on Programmed Cell Death was held in the Shanghai Science Center of the Chinese Academy of Sciences on September 8-12, 1996. A number of key issues in apoptosis were discussed at the meeting, and progress in major areas of apopto sis research was summarized by expert participants at the meeting and published by Plenum Publishing Corporation as a book entitled Programmed Cell Death. In the last six years, we have witnessed a real explosion in our knowledge on how cells undergo apoptosis, thereby participating in various developmental and pathophysiological processes. At this ever exciting time, we organized the 2nd International Symposium on Programmed Cell Death.