Programmed Cell Death In Cancer Progression And Therapy
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Programmed Cell Death In Cancer Progression And Therapy
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Author : Roya Khosravi-Far
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-12-29
Programmed Cell Death In Cancer Progression And Therapy written by Roya Khosravi-Far and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-29 with Medical categories.
Programmed cell death (PCD) plays pivotal roles in tumor progression, cancer therapeutics and resistance of tumor cells to therapy. This book examines the mechanisms involved in mediating and regulating PCD in cancer. It also provides a detailed indication of the utility of PCD in cancer therapy. The book features chapters on the current and future of RNA interference in therapeutics and Pathways involved in Stem Cell Survival and Death.
Apoptosis In Cancer Pathogenesis And Anti Cancer Therapy
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Author : Christopher D. Gregory
language : en
Publisher: Springer
Release Date : 2016-08-24
Apoptosis In Cancer Pathogenesis And Anti Cancer Therapy written by Christopher D. Gregory and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-24 with Medical categories.
This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews. Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.
Programmed Cell Death
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Author : Hala Gali-Muhtasib
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-01-15
Programmed Cell Death written by Hala Gali-Muhtasib and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-15 with Science categories.
This book incorporates developments in our understanding of cell death mechanisms and highlights recent advances in programmed cell death regulation processes. It provides the reader with the network of pathways targeted by herbal anticancer drugs and discusses the role of endoplasmic reticulum stress in cell death mechanisms in addition to highlighting the mechanisms of autophagy and its role in diseases. This book provides valuable material for researchers and for teaching postgraduate students. Emphasis on recent advances and their clinical applications offers insights to researchers that will likely lead to the development of novel therapeutic approaches.
Mutant P53 In Cancer Progression And Personalized Therapeutic Treatments
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Author : Marco Cordani
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-22
Mutant P53 In Cancer Progression And Personalized Therapeutic Treatments written by Marco Cordani and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-22 with Medical categories.
Programmed Cell Death
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Author : Roya Khosravi-Far
language : en
Publisher: Elsevier
Release Date : 2008-07-29
Programmed Cell Death written by Roya Khosravi-Far and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-29 with Science categories.
One of the major goals of researchers in the field of apoptosis is to identify targets for novel therapies in cancer, AIDS, and Alzheimer’s disease. Understanding the molecular mechanisms of the various components of the apoptotic pathways is the first step to reaching this goal. The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E. Sulston (UK) "for their discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental aspect of embryonic development, normal cellular turnover and maintenance of homeostasis (maintaining a stable, constant environment) on the one hand, and aging and disease on the other. This volume addresses the significant advances with the techniques that are being used to analyze cell death. * This volume provides the necessary, trusted methods to carry out this research on these latest therapeutic techniques. Once researchers understand the molecular mechanisms of the apoptotic pathways, they can begin to develop new therapies. * Presents key methods on studying tumors and how these cancer cells evade cell death. * Eliminates searching through many different sources to avoid pitfalls so the same mistakes are not made over and over.
Apoptosis In Normal Development And Cancer
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Author : M Sluyser
language : en
Publisher: CRC Press
Release Date : 2002-09-11
Apoptosis In Normal Development And Cancer written by M Sluyser and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-11 with Medical categories.
In apoptosis in the mammalian system, cells have a finite life - they develop, are used and then die. Cancer cells escape this programmed routine but, from an understanding of apoptosis, they can be programmed to die. This book addresses the
Selected Aspects Of Cancer Progression Metastasis Apoptosis And Immune Response
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Author : Hans E. Kaiser
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-05-20
Selected Aspects Of Cancer Progression Metastasis Apoptosis And Immune Response written by Hans E. Kaiser and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-20 with Medical categories.
The processes of tumor metastasis, apoptosis and anti-tumor immune response are among the most complex yet rapidly advancing fields in the area of cancer research. This monograph, with its leading authorship, presents a comprehensive coverage of the recent advances in the various key concepts in these fundamental aspects of human cancer. It contains state-of-the-science reviews on invasion, metastasis, angiogenesis, apoptosis and immunologic aspects related to cancer.
Apoptosis In Hormone Dependent Cancers
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Author : Martin Tenniswood
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Apoptosis In Hormone Dependent Cancers written by Martin Tenniswood and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
It is now widely accepted that cells have the ability to initiate a program of gene-directed death, a process called "apoptosis" which may also be used as an innovative strategy for therapeutic intervention in cancer therapy. Experts in this area report on the regulation and control of apoptosis in hormone dependent (neoplastic) tissue and the possibility to exploit active cell death for therapeutic application.
Death Receptors In Cancer Therapy
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Author : Wafik S. El-Deiry
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-15
Death Receptors In Cancer Therapy written by Wafik S. El-Deiry and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-15 with Medical categories.
An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression of cancer, and combination therapy with death ligands.
Apoptosis And Cancer
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Author : Seamus J. Martin
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 1997
Apoptosis And Cancer written by Seamus J. Martin and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Apoptosis categories.
The past five years have witnessed an explosion of research efforts in the study of how cells die. This book provides an up-to-date overview of our current knowledge of apoptosis and how discoveries in this area impact on our understanding of cancer. By synthesizing many of the recent developments in this area and placing them in perspective, it fulfills an important need. All the contributions are written by experts in their respective fields. The first two chapters give a basic introduction to the cell death machinery and its role in tumor development and progression; subsequent chapters cover current aspects of apoptosis research, including the involvement of cell cycle-related proteins (e.g. cyclin-dependent kinases) in apoptosis, the role of Bcl-2, Bcr-Abl, Rb, p53 and myc in the regulation of cell death, and apoptosis in the context of specific neoplasms such as cancer of the prostate, kidney, leukemia and neuroblastoma. It is also discussed how insights into the regulation of apoptosis may be exploited for designing new drugs aimed at eliminating malignant cells. Compiling the most recent research results on the relationship between apoptosis and cancer in one handy volume, this book will provide a valuable reference for scientists working in cancer research as well as newcomers to the field.