Progress In In Vitro Toxicology Volume 6
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Progress In In Vitro Toxicology Volume 6
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Author : AM Goldberg (Ed)
language : en
Publisher:
Release Date : 1988
Progress In In Vitro Toxicology Volume 6 written by AM Goldberg (Ed) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with categories.
Progress In In Vitro Toxicology
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Author : Alan M. Goldberg
language : en
Publisher: Mary Ann Liebert
Release Date : 1988
Progress In In Vitro Toxicology written by Alan M. Goldberg and has been published by Mary Ann Liebert this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Toxicity categories.
In Vitro Toxicology A Progress Report From The Johns Hopkins Center For Alternatives To Animal Testing Volume 3
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Author : AM Goldberg (Ed)
language : en
Publisher:
Release Date : 1985
In Vitro Toxicology A Progress Report From The Johns Hopkins Center For Alternatives To Animal Testing Volume 3 written by AM Goldberg (Ed) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with categories.
Validation Of Alternative Methods For Toxicity Testing
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Author : Chantra Eskes
language : en
Publisher: Springer
Release Date : 2016-09-26
Validation Of Alternative Methods For Toxicity Testing written by Chantra Eskes and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-26 with Medical categories.
This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcriptomics, and for methods derived from pathway-based concepts in toxicology. Validation of Alternative Methods for Toxicity Testing is divided into two sections, in the first, practical insights are given on the state-of-the-art and on approaches that have resulted in successfully validated and accepted alternative methods. The second section focuses on the evolution of validation principles and practice that are necessary to ensure fit-for-purpose validation that has the greatest impact on international regulatory acceptance of alternative methods. In this context validation needs to keep pace with the considerable scientific advancements being made in toxicology, the availability of sophisticated tools and techniques that can be applied in a variety of ways, and the increasing societal and regulatory demands for better safety assessment. This book will be a useful resource for scientists in the field of toxicology, both from industry and academia, developing new test methods, strategies or techniques, as well as Governmental and regulatory authorities interested in understanding the principles and practicalities of validation of alternative methods for toxicity testing.
In Vitro Toxicology
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Author : Alok Dhawan
language : en
Publisher: Academic Press
Release Date : 2017-11-13
In Vitro Toxicology written by Alok Dhawan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-13 with Science categories.
In Vitro Toxicology details the protocols and methods of in vitro testing, highlighting the usefulness of models, methods and the cost-effectiveness and reproducibility of such methodologies. The current approaches and strategies required to develop an easy, reliable, validated and high throughput system for use in alternative animal models to circumvent in vivo testing are discussed in detail. The book also includes chapters on the principles involved in the general selection and use of models that address safety concerns, regulatory acceptance and the current understandings and strategies for the identification of biomarkers in toxicity testing. Furthermore, principles involved in the general selection and use of models that address the issues of safety concerns and regulatory acceptance of these models are discussed, making the book beneficial to students, scientists, and regulators working in toxicology, as well as those in the field of chemicals and the safety assessment of novel materials. Discusses new techniques and protocols in a clear and concise manner includes examinations of nanotoxicity, genotoxicity and carcinogenicity Explains practical laboratory methods and the theories behind in vitro testing
In Vitro Toxicity Testing
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Author : John M. Frazier
language : en
Publisher: CRC Press
Release Date : 1992-01-31
In Vitro Toxicity Testing written by John M. Frazier and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-01-31 with Medical categories.
This volume focuses on the potential application of in vitro procedures to identify and quantify the toxicological risk to target organs associated with the use of commerical products and therapeutic drugs.;Revealing how the results of in vitro toxicity testing can be used in safety assessment, In Vitro Toxicity Testing: explores whether existing test methods can accomplish the necessary goals and, if not, what research is needed to make these techniques a practical reality; presents the current status of toxicity testing in the areas of hepatotoxicity, renal toxicity, ocular irritation, and many others; outlines the role of validation in technology transfer from the research laboratory to safety evaluation; examines testing strategies and regulatory acceptance and addresses common concerns about the ultimate utilization of available methods in chemical safety/hazard considerations; and analyzes the perspective of industrial and regulatory agencies on the application of in vitro toxicity testing.;Generously referenced with over 1400 literature citations, In Vitro Toxicity Testing is for academic, industrial, and regulatory toxicologists; applied, molecular, and cell biologists; pharmacologists; animal welfare activists; and graduate students in pharmacology and toxicology courses.
Dermatotoxicology 4ed
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Author : Francis Nicholas Marzulli
language : en
Publisher: CRC Press
Release Date : 1991-06-01
Dermatotoxicology 4ed written by Francis Nicholas Marzulli and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-06-01 with Medical categories.
A guide to the field of dermatotoxicology. This edition includes fundamental information on the mechanisms of action of toxic substances on skin as well as practical information on the varied responses of skin to specific toxic substances and approaches to evaluating dermal toxicity. Other topics discussed include: hostile natural elements, such as ultraviolet radiation, poisonous plants, man-made detergents and chemicals; problems associated with chronic occupational skin exposure to toxic chemicals; animal alternative research programmes; carcinogenic and Photo Carcinogenic Potential Of Xenobiotic Chemicals; Oculotoxicity; Risk assessment and management; and cosmetic safety. Anatomical factors affecting barrier functions/ lipids of the permeability barrier/the skin immune system.
In Vitro Toxicology
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Author : Alan M. Goldberg
language : en
Publisher: Mary Ann Liebert
Release Date : 1991
In Vitro Toxicology written by Alan M. Goldberg and has been published by Mary Ann Liebert this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.
Textbook Of Cosmetic Dermatology
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Author : Robert Baran
language : en
Publisher: CRC Press
Release Date : 1998-10-01
Textbook Of Cosmetic Dermatology written by Robert Baran and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-10-01 with Medical categories.
This text examines the concept of cosmetology and developments in surgical and clinical techniques in cosmetic skin care.
Dermatotoxicology Methods
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Author : Francis N. Marzulli
language : en
Publisher: CRC Press
Release Date : 2019-05-07
Dermatotoxicology Methods written by Francis N. Marzulli and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-07 with Medical categories.
This work presents and evaluates methods employed to identify the potential of certain types of chemicals to adversely affect the skin. A variety of test methods are included such as tests for skin penetration, metabolism, irritation, the skin immune system, photo effects, skin cancer, and topical effects of retinoids and depigmenting chemicals. Tests for chemicals that affect the reproductive and nervous system are also included. Both animal and human tests that have been standardised and tests that are under development and employ animal alternatives are addressed in this book. Besides different testing methods, a rationale for accepting non-animal models and a review of some regulatory agency discussions about animal alternative tests are included.