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Progress In The Chemistry Of Organic Natural Products 110
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Author : A. Douglas Kinghorn
language : en
Publisher: Springer Nature
Release Date : 2019-10-16
Progress In The Chemistry Of Organic Natural Products 110 written by A. Douglas Kinghorn and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-16 with Science categories.
The book summarizes important aspects of cheminformatics that are relevant for natural product research. It highlights cheminformatics tools that help to match natural products with their respective biological targets or off-targets, and discusses the potential and limitations of this approach.
Progress In The Chemistry Of Organic Natural Products 99
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Author : A. Douglas Kinghorn
language : en
Publisher:
Release Date : 2014-08-31
Progress In The Chemistry Of Organic Natural Products 99 written by A. Douglas Kinghorn and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-31 with categories.
Progress In The Chemistry Of Organic Natural Products 104
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Author : A. Douglas Kinghorn
language : en
Publisher: Springer
Release Date : 2017-01-25
Progress In The Chemistry Of Organic Natural Products 104 written by A. Douglas Kinghorn and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-25 with Science categories.
The first contribution describes apolar and polar molecular fossils and, in particular biomarkers, along the lines usually followed in organic chemistry textbooks, and points to their bioprecursors when available. Thus, the apolar compounds are divided in linear and branched alkanes followed by alicyclic compounds and aromatic and heterocyclic molecules, and, in particular, the geoporphyrins. The polar molecular fossils contain as functional groups or constituent units ethers, alcohols, phenols, carbonyl groups, flavonoids, quinones, and acids, or are polymers like kerogen, amber, melanin, proteins, or nucleic acids. The final sections discuss the methodology used and the fundamental processes encountered by the biomolecules described, including diagenesis, catagenesis, and metagenesis. The second contribution covers the distribution of phthalides in nature and the findings in the structural diversity, chemical reactivity, biotransformations, syntheses, and bioactivity of natural and semisynthetic phthalides.
Fortschritte Der Chemie Organischer Naturstoffe
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Author : H. Grisebach
language : en
Publisher:
Release Date : 1978
Fortschritte Der Chemie Organischer Naturstoffe written by H. Grisebach and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with categories.
Progress In The Chemistry Of Organic Natural Products 102
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Author : A. Douglas Kinghorn
language : en
Publisher: Springer
Release Date : 2016-07-05
Progress In The Chemistry Of Organic Natural Products 102 written by A. Douglas Kinghorn and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-05 with Science categories.
The first contribution reviews the phytochemical, chemical, and biological literature on members of the ingenane class of diterpenoids from their first isolation in 1968 through 2015, highlighting unresolved issues both common to phorboids and specific to ingenol derivatives. The biogenesis of ingenol is discussed in the light of the Jakupovic proposal of a dissection between the formation of the macrocyclic Euphorbia diterpenoids and the phorboids, and the clinical development of ingenol mebutate is chronicled in the light of its “reverse-pharmacology” focus. The second contribution offers a comprehensive view of the chemical wealth and the taxonomic problems currently impeding chemical and biological investigations of the genus Laurencia. It addresses the botanical description and the growth and population dynamics of the genus, as well as its chemical diversity and ecological relations; the secondary metabolites as well as their sources of isolation; and finally the biological activity.
Progress In The Chemistry Of Organic Natural Products 113
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Author : A Douglas Kinghorn
language : en
Publisher: Springer Nature
Release Date : 2021-04-16
Progress In The Chemistry Of Organic Natural Products 113 written by A Douglas Kinghorn and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-16 with Science categories.
In this book, chemical studies are described mainly from literature reports appearing since 2000, inclusive of investigations performed by the present authors, on the diversity in secondary metabolites of Ligularia growing in the Hengduan Mountains area of China, focusing on eremophilane sesquiterpenoids and other metabolites. More than 100 Ligularia species and their related genera in the plant family Senecioneae plants (Cremanthodium, Cacalia, Senecio, and others) grow in East Asia. For many years, researchers have studied the chemical constituents of these plants, and terpenoids, flavonoids, steroids, alkaloids, and aromatic compounds have been isolated. Among these, in particular, numerous sesquiterpenoids were reported. Within this book terpenoids and aromatic compounds (total 1049), both previously unknown and known, are presented. Finally, genetic studies and synthesis investigations are briefly reviewed.
Progress In The Chemistry Of Organic Natural Products 115
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Author : A. Douglas Kinghorn
language : en
Publisher: Springer Nature
Release Date : 2021-04-02
Progress In The Chemistry Of Organic Natural Products 115 written by A. Douglas Kinghorn and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-02 with Science categories.
This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.
Progress In The Chemistry Of Organic Natural Products
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Author :
language : en
Publisher:
Release Date : 1981
Progress In The Chemistry Of Organic Natural Products written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with categories.
Progress In The Chemistry Of Organic Natural Products
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Author :
language : en
Publisher:
Release Date : 2003-12-18
Progress In The Chemistry Of Organic Natural Products written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-18 with categories.
Progress In The Chemistry Of Organic Natural Products 116
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Author : A. Douglas Kinghorn
language : en
Publisher: Springer
Release Date : 2021-10-27
Progress In The Chemistry Of Organic Natural Products 116 written by A. Douglas Kinghorn and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-27 with Science categories.
This volume describes several highly diverse subjects: Chapter 1 explores marine biodiscovery of the North-eastern Atlantic off the coast of Ireland as a model for best practice in research. The second chapter investigates Brazilian Chemical Ecology and examples of insect-plant communication studies that are mediated by natural products demonstrate the beautiful interconnectedness of species in a biome. Our third chapter comprises the advances in the science of the sesquiterpene quinone, perezone, which in 1852 was the first natural product isolated in crystalline form in the New World. The last two chapters are from a Vietnamese group and the first of these follows the phytochemistry, pharmacology, and ethnomedical uses of the genus Xanthium, which produces interesting sulfur and nitrogen containing natural products. Finally, the genus Desmos is discussed, where an overview of its constituent natural products and their in vitro pharmacological potential is described.