Protein Compartmentalization
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Protein Compartmentalization
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Author : Arnold W. Strauss
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Protein Compartmentalization written by Arnold W. Strauss and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known of the chemical con stitution of biological systems, the manner in which information was transmitted from one organism to another, or the extent to which the chemical basis of life is unified. The picture today is dramatically different. We have an almost bewil dering variety of information detailing many different aspects of life at the molecular level. These great advances have brought with them some breath taking insights into the molecular mechanisms used by nature for replicating, dis tributing, and modifying biological information. We have learned a great deal about the chemical and physical nature of the macromolecular nucleic acids and proteins, and the manner in which carbohydrates, lipids, and smaller molecules work together to provide the molecular setting of living systems. It might be said that these few decades have replaced a near vacuum of information with a very large surplus. It is in the context of this flood of information that this series of monographs on molecular biology has been organized. The idea is to bring together in one place, between the covers of one book, a concise assessment of the state of the subject in a well-defined field.
Protein Compartmentalization
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Author : Arnold W. Strauss
language : en
Publisher:
Release Date : 1986-01-01
Protein Compartmentalization written by Arnold W. Strauss and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-01-01 with Biological transport categories.
Diffusion Compartmentalization And Single Molecule Detection Of Proteins In Bacterial Cells
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Author : Ellen M. Judd
language : en
Publisher:
Release Date : 2004
Diffusion Compartmentalization And Single Molecule Detection Of Proteins In Bacterial Cells written by Ellen M. Judd and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Compartmentalization Of The Cyclic Nucleotide Dependent Protein Kinases And Their Substrates
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Author : Sean Philip Collins
language : en
Publisher:
Release Date : 2001
Compartmentalization Of The Cyclic Nucleotide Dependent Protein Kinases And Their Substrates written by Sean Philip Collins and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.
Biocatalysis For Practitioners
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Author : Gonzalo de Gonzalo
language : en
Publisher: John Wiley & Sons
Release Date : 2021-07-19
Biocatalysis For Practitioners written by Gonzalo de Gonzalo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-19 with Science categories.
This reference book originates from the interdisciplinary research cooperation between academia and industry. In three distinct parts, latest results from basic research on stable enzymes are explained and brought into context with possible industrial applications. Downstream processing technology as well as biocatalytic and biotechnological production processes from global players display the enormous potential of biocatalysts. Application of "extreme" reaction conditions (i.e. unconventional, such as high temperature, pressure, and pH value) - biocatalysts are normally used within a well defined process window - leads to novel synthetic effects. Both novel enzyme systems and the synthetic routes in which they can be applied are made accessible to the reader. In addition, the complementary innovative process technology under unconventional conditions is highlighted by latest examples from biotech industry.
Protein Engineering And Design
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Author : Sheldon J. Park
language : en
Publisher: CRC Press
Release Date : 2009-09-25
Protein Engineering And Design written by Sheldon J. Park and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-25 with Medical categories.
Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fields, Protein Engineering and Design aims to cultivate a synergistic approach to protein science
Inducing Targeted Protein Degradation
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Author : Philipp Cromm
language : en
Publisher: John Wiley & Sons
Release Date : 2023-02-06
Inducing Targeted Protein Degradation written by Philipp Cromm and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-06 with Medical categories.
Enables drug developers in academia and industry to expand the range of accessible drug targets through induced protein degradation Since the introduction of the PROTAC technology in 2015, targeted protein degradation has greatly increased the range of druggable protein targets, enabling pharma companies to develop completely novel therapeutics. Inducing Targeted Protein Degradation is a timely guide to navigating the complexities of the subject and understanding its practical application, with an eye on expanding the range of druggable targets. In Inducing Targeted Protein Degradation, readers will find the most recent information on: Cellular mechanisms of targeted protein degradation and current approaches to retarget these mechanisms for therapeutic use A comparison of different induced degradation approaches, including PROTAC, light-activated degradation, and CHAMPS Drug development aspects such as DMPK optimization and selection of clinical candidates A discussion of the potential of targeted degradation for expanding the range of druggable protein targets Inducing Targeted Protein Degradation will serve as a practice-oriented reference on induced protein degradation for drug discovery professionals and for researchers employing chemical biology approaches.
Biophysics For Therapeutic Protein Development
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Author : Linda O. Narhi
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-02-26
Biophysics For Therapeutic Protein Development written by Linda O. Narhi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-26 with Medical categories.
This book can be used to provide insight into this important application of biophysics for those who are planning a career in protein therapeutic development, and for those outside this area who are interested in understanding it better. The initial chapters describe the underlying theory, and strengths and weaknesses of the different techniques commonly used during therapeutic development. The majority of the chapters discuss the applications of these techniques, including case studies, across the product lifecycle from early discovery, where the focus is on identifying targets, and screening for potential drug product candidates, through expression and purification, large scale production, formulation development, lot-to-lot comparability studies, and commercial support including investigations.
Protein Lipid Interactions
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Author : C.Reyes Mateo
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-01-31
Protein Lipid Interactions written by C.Reyes Mateo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-31 with Science categories.
Biological membranes have long been identified as key elements in a wide variety of cellular processes including cell defense communication, photosynthesis, signal transduction, and motility; thus they emerge as primary targets in both basic and applied research. This book brings together in a single volume the most recent views of experts in the area of protein–lipid interactions, providing an overview of the advances that have been achieved in the field in recent years, from very basic aspects to specialized technological applications. Topics include the application of X-ray and neutron diffraction, infrared and fluorescence spectroscopy, and high-resolution NMR to the understanding of the specific interactions between lipids and proteins within biological membranes, their structural relationships, and the implications for the biological functions that they mediate. Also covered in this volume are the insertion of proteins and peptides into the membrane and the concomitant formation of definite lipid domains within the membrane.