Protein Metal Interactions
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Protein Metal Interactions
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Author : Mendel Friedman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Protein Metal Interactions written by Mendel Friedman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Metal ions and proteins are ubiquitous. Therefore, not surprisingly, new protein-metal interactions continue to be dis covered, and their importance is increasingly recognized in both physical and life sciences. Because the subject matter is so broad and affects so many disciplines, in organizing this Symposium, I sought participation of speakers with the broadest possible range of interests. Twenty-two accepted my invitation. To supplement the verbal presentations, the Proceedings include five closely re lated invited contributions. The ideas expressed are those of the various authors and are not necessarily approved or rejected by any agency of the United States Government. No official recommendation concerning the sub ject matter or products discussed is implied in this book. This book encompasses many aspects of this multifaceted field. Topics covered represent biochemical, immunochemical, bioorganic, biophysical, metabolic, nutritional, medical, physiological, toxi cological, environmental, textile, and analytical interests. The discoveries and developments in any of these areas inevitably illumine others. I feel that a main objective of this Symposium, bringing together scientists with widely varied experiences yet with common interests in protein-metal interactions, so that new understanding and new ideas would result has been realized. I hope that the reader enjoys and benefits from reading about the fascinat ing interactions of metal ions and proteins as much as I did.
Protein Metal Interactions
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Author : Mendel Friedman
language : en
Publisher:
Release Date : 1974
Protein Metal Interactions written by Mendel Friedman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1974 with Metals categories.
Metal Ions In Biological Systems
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Author : Astrid Sigel
language : en
Publisher: CRC Press
Release Date : 2001-01-30
Metal Ions In Biological Systems written by Astrid Sigel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-01-30 with Medical categories.
"Focuses on the vibrant area of probing enzymes or proteins by metal ions and small complexes. Offers a summary of the basic characteristics of the amide bond, emphasizing its proton and metal ion interactions, including a quantitative analysis of its hydrolysis and formation."
Defining The Roles Of Protein Protein And Protein Metal Interactions In Biological Electron Transfer Processes Metal
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Author : DAVID JAMES DETLEFSEN
language : en
Publisher:
Release Date : 1990
Defining The Roles Of Protein Protein And Protein Metal Interactions In Biological Electron Transfer Processes Metal written by DAVID JAMES DETLEFSEN and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with categories.
physiological partner, azurin. These studies showed the binding between Zn(II) c551 and Cu(II) azurin to be weak at $
Plant Metal Interactions
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Author : Sudhakar Srivastava
language : en
Publisher: Springer
Release Date : 2019-07-26
Plant Metal Interactions written by Sudhakar Srivastava and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-26 with Science categories.
Metal toxicity and deficiency are both common abiotic problems faced by plants. While metal contamination around the world is a critical issue, the bioavailability of some essential metals like zinc (Zn) and selenium (Se) can be seriously low in other locations. The list of metals spread in high concentrations in soil, water and air includes several toxic as well as essential elements, such as arsenic (As), cadmium (Cd), chromium (Cr), aluminum (Al), and selenium (Se). The problems for some metals are geographically confined, while for others, they are widespread. For instance, arsenic is an important toxic metalloid whose contamination in Southeast Asia and other parts of world is well documented. Its threats to human health via food consumption have generated immense interest in understanding plants’ responses to arsenic stress. Metals constitute crucial components of key enzymes and proteins in plants. They are important for the proper growth and development of plants. In turn, plants serve as sources of essential elements for humans and animals. Studies of their physiological effects on plants metabolism have led to the identification of crucial genes and proteins controlling metal uptake and transport, as well as the sensing and signaling of metal stresses. Plant-Metal Interactions sheds light on the latest development and research in analytical biology with respect to plant physiology. More importantly, it showcases the positive and negative impacts of metals on crop plants growth and productivity.
Metal Ions In Biological Systems
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Author : Astrid Sigel
language : en
Publisher: CRC Press
Release Date : 1996-02-05
Metal Ions In Biological Systems written by Astrid Sigel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-02-05 with Science categories.
Volume 32 covers metal ion bonding to phosphate, sugar and nucleobase residues; the ambidentate as well as the stacking properties of nucleotides; kinetic aspects as well as properties of nucleobase and nucleotide analogs; and the oligonucleotides and nucleic acids. It examines electron transfer reactions over a large number of base repairs in DNA, the role of metal ions in ribozymes, ternary metal-nucleic acid base-protein complexes, metal responsive gene regulation, and the structure-activity relationships of anticancer drugs and their action on DNA, including cisplatin and the role of proteins.
Bacteria Metal Interactions
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Author : Daad Saffarini
language : en
Publisher: Springer
Release Date : 2015-05-20
Bacteria Metal Interactions written by Daad Saffarini and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-20 with Science categories.
This book provides a detailed description and analysis of the reduction and metabolism of metals and metalloids by sulfate reducing bacteria. The molecular mechanisms of bacterial resistance to copper are examined as well as extracellular electron transfer and bacterial metal oxide respiration. Furthermore, in this book enrichment, isolation, and physiology of magnetotactic bacteria are discussed. The interactions of bacteria with metals in natural environments and their role in metal cycling have been studied for decades. Advances in studies of bacteria-metal interactions identified numerous important aspects of these interactions, such as bioremediation of metal-contaminated environments, the role of metals in redox reactions and other cellular functions, as well as the role of metals in toxicity and infection. Microbiologists, environmental scientists, and students interested in microbe interactions with metals and their effect on the environment and their application in biotechnology will be interested in the topics discussed in the book.
Protein Folding And Metal Ions
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Author : Cláudio M. Gomes
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Protein Folding And Metal Ions written by Cláudio M. Gomes and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
The role of metal ions in protein folding and structure is a critical topic to a range of scientists in numerous fields, particularly those working in structural biology and bioinorganic chemistry, those studying protein folding and disease, and those involved in the molecular and cellular aspects of metals in biological systems. Protein Folding an
Metalloprotein Active Site Assembly
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Author : Michael K. Johnson
language : en
Publisher: John Wiley & Sons
Release Date : 2017-08-14
Metalloprotein Active Site Assembly written by Michael K. Johnson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-14 with Science categories.
Summarizes the essential biosynthetic pathways for assembly of metal cofactor sites in functional metalloproteins Metalloprotein Active Site Assembly focuses on the processes that have evolved to orchestrate the assembly of metal cofactor sites in functional metalloproteins. It goes beyond the simple incorporation of single metal ions in a protein framework, and includes metal cluster assembly, metal-cofactor biosynthesis and insertion, and metal-based post-translational modifications of the protein environments that are necessary for function. Several examples of each of these areas have now been identified and studied; the current volume provides the current state-of-the-art understanding of the processes involved. An excellent companion to the earlier book in this series Metals in Cells—which discussed both the positive and negative effects of cellular interactions with metals—this comprehensive book provides a diverse sampling of what is known about metalloprotein active site assembly processes. It covers all major biological transition metal components (Mn, Fe, Co, Ni, Mo), as well as the other inorganic components, metal-binding organic cofactors (e.g., heme, siroheme, cobalamin, molybdopterin), and post-translationally modified metal binding sites that make up the patchwork of evolved biological catalytic sites. The book compares and contrasts the biosynthetic assembly of active sites involving all biological metals. This has never been done before since it is a relatively new, fast-developing area of research. Metalloprotein Active Site Assembly is an ideal text for practitioners of inorganic biochemistry who are studying the biosynthetic pathways and gene clusters involved in active site assembly, and for inorganic chemists who want to apply the concepts learned to potential synthetic pathways to active site mimics.
Metalloproteomics
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Author : Eugene Permyakov
language : en
Publisher: John Wiley & Sons
Release Date : 2009-08-13
Metalloproteomics written by Eugene Permyakov and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-13 with Science categories.
Synthesizes the current knowledge in the field and provides new insights into medical applications Metalloproteomics is the large-scale study of metal-binding proteins. These proteins, which represent about one quarter of all the proteins in the Protein Data Bank, play important roles in all biological systems and all biological processes. Metalloproteomics provides the latest information on all major families of metal-binding proteins, including their structural, physico-chemical, and functional properties, enabling readers to better understand these proteins. Moreover, the book demonstrates how understanding the structures, properties, and functions of intracellular and extracellular metal-binding proteins may unlock the key to drug development for the treatment of a myriad of diseases. Written by Eugene Permyakov, an international expert and pioneer in the structural analysis of metal-binding proteins, the book offers Theoretical introduction to cation binding Broad range of methods for investigating the binding of different cations to proteins Characteristics of interactions of physiologically important cations of Ca, Mg, Zn, Fe, Mn, Co, Cu, Ni, Mo, W, Na, and K with proteins Detailed considerations of structural and physico-chemical properties of the metal-binding proteins Interactions of all other metal cations with proteins Interactions of different types of cations with nucleic acids Throughout the text, the author integrates principles of proteomics. In addition, detailed examples underscore the role metal-binding proteins play in health and medicine. Bringing together and analyzing all the latest findings, Metalloproteomics' scope and level of insight are unparalleled. It is recommended for biophysicists, biochemists, enzymologists, cell and molecular biologists, protein and peptide scientists, organic and bioinorganic chemists, and chemical biologists.