Protein Phosphorylation And Bio Regulation
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Protein Phosphorylation And Bio Regulation
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Author : J. Gordon
language : en
Publisher:
Release Date : 1980
Protein Phosphorylation And Bio Regulation written by J. Gordon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Chemistry, Organic categories.
Protein Phosphorylation And Bio Regulation
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Author : J. Gordon
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 1980
Protein Phosphorylation And Bio Regulation written by J. Gordon and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Medical categories.
Cellular Regulation By Protein Phosphorylation
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Author : L.M.G. Jr. Heilmeyer
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Cellular Regulation By Protein Phosphorylation written by L.M.G. Jr. Heilmeyer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
Proceedings of the NATO Advanced Study Institute on Cellular Regulation by Protein Phosphorylation held at Chateau La Londe les Maures (France), September 5-15, 1990
Reversible Protein Phosphorylation In Cell Regulation
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Author : R.L. Khandelwal
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Reversible Protein Phosphorylation In Cell Regulation written by R.L. Khandelwal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This book, published in association with the journal MOLECULAR AND CELLULAR BIOCHEMISTRY, is dedicated to Ed Krebs and Eddy Fischer in celebration of their 1992 Nobel Prize in Physiology and Medicine. Reversible protein phosphorylation is a research field pioneered and developed by Krebs and Fischer. This book contains short reviews and original research papers contributed by Krebs and Fischer's coworkers, both former and current. The contents reflect the two-way interaction between protein phosphorylation and other biomedical research fields. The chapters are grouped into four sections. The first two deal with structure/function aspects of protein kinases and protein mechanisms. Unlike many other research fields, which undergo periods of intense activity and productivity followed by relative calm, the protein phosphorylation field enjoyed continued growth both in scope and intensity, and the pace of this growth has increased markedly in recent years. This volume will provide a glimpse of the dynamism and diversity of the research activity representative of the current state of the field.
Protein Phosphorylation In Health And Disease
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Author : Allegra Via
language : en
Publisher: Frontiers Media SA
Release Date : 2016-08-11
Protein Phosphorylation In Health And Disease written by Allegra Via and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-11 with Genetics categories.
Protein phosphorylation is one of the most abundant reversible post-translational modifications in eukaryotes. It is involved in virtually all cellular processes by regulating protein function, localization and stability and by mediating protein-protein interactions. Furthermore, aberrant protein phosphorylation is implicated in the onset and progression of human diseases such as cancer and neurodegenerative disorders. In the last years, tens of thousands of in vivo phosphorylation events have been identified by large-scale quantitative phospho-proteomics experiment suggesting that a large fraction of the proteome might be regulated by phosphorylation. This data explosion is increasingly enabling the development of computational approaches, often combined with experimental validation, aiming at prioritizing phosphosites and assessing their functional relevance. Some computational approaches also address the inference of specificity determinants of protein kinases/phosphatases and the identification of phosphoresidue recognition domains. In this context, several challenging issues are still open regarding phosphorylation, including a better understanding of the interplay between phosphorylation and allosteric regulation, agents and mechanisms disrupting or promoting abnormal phosphorylation in diseases, the identification and modulation of novel phosphorylation inhibitors, and so forth. Furthermore, the determinants of kinase and phosphatase recognition and binding specificity are still unknown in several cases, as well as the impact of disease mutations on phosphorylation-mediated signaling. The articles included in this Research Topic illustrate the very diverse aspects of phosphorylation, ranging from structural changes induced by phosphorylation to the peculiarities of phosphosite evolution. Some also provide a glimpse into the huge complexity of phosphorylation networks and pathways in health and disease, and underscore that a deeper knowledge of such processes is essential to identify disease biomarkers, on one hand, and design more effective therapeutic strategies, on the other.
Peptides And Protein Phosphorylation
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Author : B.E. Kemp
language : en
Publisher: CRC Press
Release Date : 2018-01-18
Peptides And Protein Phosphorylation written by B.E. Kemp and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Medical categories.
This comprehensive volume focuses on the ways in which synthetic peptides have been exploited in order to expand our understanding of the molecular mechanisms involved in protein phosphorylation. It recognizes that virtually all physiological processes are regulated by protein phosphorylation. It discusses the use of synthetic peptides in studying the catalytic mechanism and regulation of protein kinases. It also includes the chemical synthesis of phosphorylated peptides and preparation of specific antisera. This incredible work has lead to the development of a new generation of peptide inhibitors with potencies of greater magnitude than those previously known. Everyone involved with biochemistry and molecular biology will find this one-of-a-kind resource fascinating and filled with useful information.
Protein Phosphorylation In Health And Disease
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Author : Shirish Shenolikar
language : en
Publisher: Academic Press
Release Date : 2012-02-28
Protein Phosphorylation In Health And Disease written by Shirish Shenolikar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-28 with Medical categories.
This volume explores some of the most exciting recent advances in basic research on protein phosphorylation in health and disease and how this knowledge is leading to advances in the various fields. Contributions from leading authorities Informs and updates on all the latest developments in the field
Protein Kinases And Stress Signaling In Plants
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Author : Girdhar K. Pandey
language : en
Publisher: John Wiley & Sons
Release Date : 2021-03-08
Protein Kinases And Stress Signaling In Plants written by Girdhar K. Pandey and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-08 with Science categories.
A comprehensive review of stress signaling in plants using genomics and functional genomic approaches Improving agricultural production and meeting the needs of a rapidly growing global population requires crop systems capable of overcoming environmental stresses. Understanding the role of different signaling components in plant stress regulation is vital to developing crops which can withstand abiotic and biotic stresses without loss of crop yield and productivity. Emphasizing genomics and functional genomic approaches, Protein Kinases and Stress Signaling in Plants is a comprehensive review of cutting-edge research on stress perception, signal transduction, and stress response generation. Detailed chapters cover a broad range of topics central to improving agricultural production developing crop systems capable of overcoming environmental stresses to meet the needs of a rapidly growing global population. This book describes the field of protein kinases and stress signaling with a special emphasis on functional genomics. It presents a highly valuable contribution in the field of stress perception, signal transduction and generation of responses against one or multiple stress signals. This timely resource: Summarizes the role of various kinases involved in stress management Enumerates the role of TOR, GSK3-like kinase, SnRK kinases in different physiological conditions Examines mitogen-activated protein kinases (MAPKs) in different stresses Describes the different aspects of calcium signaling under different stress conditions Examines photo-activated kinases (PAPKs) in varying light conditions Briefs the presence of tyrosine kinases in plants Highlights the cellular functions of receptor ]like protein kinases (RLKs) Possible implication of these kinases in developing stress tolerant crops Protein Kinases and Stress Signaling in Plants: Functional Genomic Perspective is an essential resource for researchers and students in the fields of plant molecular biology and signal transduction, plant responses to stress, plant cell signaling, plant protein kinases, plant biotechnology, transgenic plants and stress biology.
Reviews In Cell Biology And Molecular Medicine
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Author : Robert A. Meyers
language : en
Publisher: Wiley-Blackwell
Release Date : 2008-04-29
Reviews In Cell Biology And Molecular Medicine written by Robert A. Meyers and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-29 with Science categories.
"This series is a classic..." - Molecular Medicine Today/Trends in Molecular Medicine The second edition of this highly acclaimed, sixteen-volume Encyclopedia now contains 150 new articles and extended coverage of cell biology. It is thus the most comprehensive and most detailed treatment of molecular biology, cell biology and molecular medicine available today -- designed in collaboration with a founding board of 10 Nobel laureates. As such, the Encyclopedia provides a single-source library of the molecular basis of life, with a focus on molecular medicine, discussing in detail the latest advances of the post-genomic era. Each of the approximately 425 articles is written as a self-contained treatment, beginning with an outline and a key word section plus definitions. Peer-reviewed, they are written in a review-like style, complemented by an extensive bipartite bibliography of reviews and books as well as primary papers. A glossary of basic terms completes each volume and defines the most commonly used terms in molecular biology. Together with the introductory illustrations found in each volume, the articles are comprehensible for readers at every level without resorting to a dictionary, textbook, or other reference. Praise for the first edition: "...an authoritative reference source of the highest quality. ... It is extremely well written and well illustrated..." - American Reference Books Annual (Library & Information Science Annual) "This series can be recommended without hesitation to a broad readership including students and qualified researchers... . ...articles...set-up facilitates easy reading and rapid understanding. ...overwhelming amount of valuable data." - Molecular Biology Reports ".. highly valuable and recommendable both for libraries and for laboratory use." - FEBS Letters
Principles Of Molecular Regulation
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Author : P. Michael Conn
language : en
Publisher: Springer Science & Business Media
Release Date : 2000-07-28
Principles Of Molecular Regulation written by P. Michael Conn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-07-28 with Medical categories.
With the dramatic growth in our knowledge of hormone action and the mechanisms of cell regulation, the need for an up-to-date broad-ranging survey of these processes has become pressing. In Principles of Molecular Regulation, P. Michael Conn and Anthony Means have successfully assembled a panel of leading investigators to provide an integrated review of the key areas-membrane receptor-initiated cell signaling and nuclear receptor-initiated gene regulation. Chosen for the excellence of their research as well as their demonstrated writing skills, these distinguished authors illuminate the molecular machinery underlying the regulatory processes of cells. In addition to their comprehensive review of the signaling mechanisms involving cell surface receptors, nuclear receptors, and ion channels, they detail the roles of calcium, lipids, cyclic AMP, protein kinases, and protein phosphatases. They also discuss the molecular regulation of cell proliferation and death, as well as the impact of new technologies on rational drug discovery. Capturing the excitement now present at this vibrant union of molecular biology, cell biology, and endocrinology, Principles of Molecular Regulation constitutes a major new resource for understanding the many and complex elements of biological regulation. Its up-to-date critical synthesis is certain to prove of high value to all basic and clinical investigators working with these processes today.