Protein Science Structure And Mechanism

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Structure And Mechanism In Protein Science

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Author : Alan Fersht
language : en
Publisher: Macmillan
Release Date : 1999

Structure And Mechanism In Protein Science written by Alan Fersht and has been published by Macmillan this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.

Includes four new chapters which focus on the repercussions of protein engineering for protein folding and catalysis, this new edition is a more general guide to mechanism in protein science.

Protein Science Structure And Mechanism

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Author : Anton Torres
language : en
Publisher: States Academic Press
Release Date : 2021-11-16

Protein Science Structure And Mechanism written by Anton Torres and has been published by States Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-16 with Science categories.

Macromolecules which are composed of long chains of amino acid residues are called proteins. Each protein consists of at least one long polypeptide. The sequence of gene that is encoded in the genetic code is responsible for defining the sequence of amino acids in a protein. The lifespan of protein is measured in half-life, and can range from minutes to years. Protein science is a branch of biology which attempts to develop an understanding about the role of proteins in genetics, evolution, and molecular and cell biology. It also focuses on the structure and functions of different types of proteins. This discipline employs various techniques such as protein purification, structure determination, cellular localization and chemical analysis. This book explores all the important aspects of protein science in the present day scenario. It aims to shed light on some of the unexplored aspects of protein science and the recent researches in this field. Scientists and students actively engaged in this field will find this book full of crucial and unexplored concepts.

Structure And Mechanism In Protein Science

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Author : Alan Fersht
language : en
Publisher: World Scientific Publishing Company
Release Date : 2017

Structure And Mechanism In Protein Science written by Alan Fersht and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Catalysis categories.

The three-dimensional structure of proteins -- Chemical catalysis -- The basic equations of enzyme kinetics -- Measurement and magnitude of individual rate constants -- The pH dependence of enzyme catalysis -- Practical methods for kinetics and equilibria -- Detection of intermediates in enzymatic reactions -- Stereochemistry of enzymatic reactions -- Active-site-directed and enzyme-activated irreversible inhibitors : "affinity labels" and "suicide inhibitors" -- Conformational change, allosteric regulation, motors, and work -- Forces between molecules, and binding energies -- Enzyme-substrate complementarity and the use of binding energy in catalysis -- Specificity and editing mechanisms -- Recombinant DNA technology -- Protein engineering -- Case studies of enzyme structure and mechanism -- Protein stability -- Kinetics of protein folding -- Folding pathways and energy landscapes.

Introduction To Protein Science

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Author : Arthur M. Lesk
language : en
Publisher: Oxford University Press, USA
Release Date : 2004

Introduction To Protein Science written by Arthur M. Lesk and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Amino acid sequence categories.

Useful for students on biosciences degrees, this book provides an introduction to the study of proteins. It contains the aspects related to genomics and proteomics that have paved the way for an explosion of interest in protein structure and function.

Fundamentals Of Protein Structure And Function

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Author : Engelbert Buxbaum
language : en
Publisher: Springer
Release Date : 2015-11-27

Fundamentals Of Protein Structure And Function written by Engelbert Buxbaum and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-27 with Science categories.

This book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion how misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological and medical significance of this often neglected topic. This is followed by thorough coverage of hæmoglobin and myoglobin, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins to various cell compartments and solute transport across biological membranes. Proteins in the laboratory are also covered, including a detailed description of the purification and determination of proteins, as well as their characterisation for size and shape, structure and molecular interactions. The book emphasises the link between protein structure, physiological function and medical significance. This book can be used for graduate and advanced undergraduate classes covering protein structure and function and as an introductory text for researchers in protein biochemistry, molecular and cell biology, chemistry, biophysics, biomedicine and related courses. About the author: Dr. Buxbaum is a biochemist with interest in enzymology and protein science. He has been working on the biochemistry of membrane transport proteins for nearly thirty years and has taught courses in biochemistry and biomedicine at several universities.

Introduction To Proteins

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Author : Amit Kessel
language : en
Publisher: CRC Press
Release Date : 2018-03-22

Introduction To Proteins written by Amit Kessel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-22 with Computers categories.

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the structure, function, and motion of proteins for students, faculty, and researchers at all levels. The book covers proteins and enzymes across a wide range of contexts and applications, including medical disorders, drugs, toxins, chemical warfare, and animal behavior. Each chapter includes a Summary, Exercies, and References. New features in the thoroughly-updated second edition include: A brand-new chapter on enzymatic catalysis, describing enzyme biochemistry, classification, kinetics, thermodynamics, mechanisms, and applications in medicine and other industries. These are accompanied by multiple animations of biochemical reactions and mechanisms, accessible via embedded QR codes (which can be viewed by smartphones) An in-depth discussion of G-protein-coupled receptors (GPCRs) A wider-scale description of biochemical and biophysical methods for studying proteins, including fully accessible internet-based resources, such as databases and algorithms Animations of protein dynamics and conformational changes, accessible via embedded QR codes Additional features Extensive discussion of the energetics of protein folding, stability and interactions A comprehensive view of membrane proteins, with emphasis on structure-function relationship Coverage of intrinsically unstructured proteins, providing a complete, realistic view of the proteome and its underlying functions Exploration of industrial applications of protein engineering and rational drug design Each chapter includes a Summary, Exercies, and References Approximately 300 color images Downloadable solutions manual available at www.crcpress.com For more information, including all presentations, tables, animations, and exercises, as well as a complete teaching course on proteins' structure and function, please visit the author's website: http://ibis.tau.ac.il/wiki/nir_bental/index.php/Introduction_to_Proteins_Book. Praise for the first edition "This book captures, in a very accessible way, a growing body of literature on the structure, function and motion of proteins. This is a superb publication that would be very useful to undergraduates, graduate students, postdoctoral researchers, and instructors involved in structural biology or biophysics courses or in research on protein structure-function relationships." --David Sheehan, ChemBioChem, 2011 "Introduction to Proteins is an excellent, state-of-the-art choice for students, faculty, or researchers needing a monograph on protein structure. This is an immensely informative, thoroughly researched, up-to-date text, with broad coverage and remarkable depth. Introduction to Proteins would provide an excellent basis for an upper-level or graduate course on protein structure, and a valuable addition to the libraries of professionals interested in this centrally important field." --Eric Martz, Biochemistry and Molecular Biology Education, 2012

Protein Structure And Function

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Author : Gregory A. Petsko
language : en
Publisher: New Science Press
Release Date : 2004

Protein Structure And Function written by Gregory A. Petsko and has been published by New Science Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.

Each title in the 'Primers in Biology' series is constructed on a modular principle that is intended to make them easy to teach from, to learn from, and to use for reference.

Protein Folding And Metal Ions

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Author : Cláudio M. Gomes
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Protein Folding And Metal Ions written by Cláudio M. Gomes and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.

The role of metal ions in protein folding and structure is a critical topic to a range of scientists in numerous fields, particularly those working in structural biology and bioinorganic chemistry, those studying protein folding and disease, and those involved in the molecular and cellular aspects of metals in biological systems. Protein Folding an

Introduction To Protein Science

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Author : Arthur Lesk
language : en
Publisher: Oxford University Press, USA
Release Date : 2010-03-25

Introduction To Protein Science written by Arthur Lesk and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-25 with Education categories.

Starting by describing the structure of proteins and explaining how these structures can be studied, this book goes on to illustrate the wide range of protein functions by showing how the shape of a protein is intimately linked to its function.

Mechanism In Protein Chemistry

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Author : Jack Kyte
language : en
Publisher: Garland Pub
Release Date : 1995

Mechanism In Protein Chemistry written by Jack Kyte and has been published by Garland Pub this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Science categories.

This book examines the chemical methods used to study the mechanisms of enzymatically catalyzed reactions with an emphasis on the crystallographic molecular models of active sites. The book traces the development of enzymatic mechanisms from physical organic studies of nonenzymatic catalysis through detailed examination of the specific interactions between catalytic amino acids and intermediate analogues in crystallographic molecular models. The strategies of enzymatic catalysis, such as coenzymatic assistance, approximation, strain, the use of general acid-bases, the involvement of intermediates, and conformational control, are the central topics around which the book is organized.