Protein Synthesis
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Protein Synthesis
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Author : Robin Martin
language : en
Publisher: Humana Press
Release Date : 1998-08-04
Protein Synthesis written by Robin Martin and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-08-04 with Science categories.
The synthesis of proteins from 20 or so constituent amino acids according to a strictly defined code with an accuracy of better than 1 in 10,000 at most loca tions is arguably the most complex task performed by cells. Protein Synthesis collects together methods and protocols covering a range of different approaches towards understanding how the cellular machinery accomplishes this task and how these ftinctions might be harnessed by the biotechnology industry to generate novel and useful proteins. The era in which the components of the translational machinery were being catalogued is over. This volume gathers together protocols that focus on preserving and describing the dynamic function as closely as possible. The need to understand exactly how ribosomes are positioned on messages or where tRNA molecules, translation factors, or control proteins are bound, has been appreciated by many of the authors. Several chapters that explore the fidelity and processivity of translation reflect this belief. Moreover, the fundamental importance of rRNA at the heart of the ribosome is a strong theme in a number of the protocols. These articles include in vitro and in vivo systems from bacterial, fungal, plant, and animal systems. Overall, Protein Synthesis might be characterized by the novelty of the approaches employed to illuminate the inner workings of the protein synthetic machinery as well as by the inventiveness of the attempts to harness these reactions for biotechnological applications.
Cell Free Protein Synthesis
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Author : Alexander S. Spirin
language : en
Publisher: John Wiley & Sons
Release Date : 2007-12-03
Cell Free Protein Synthesis written by Alexander S. Spirin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-03 with Science categories.
With its detailed description of membrane protein expression, high-throughput and genomic-scale expression studies, both on the analytical and the preparative scale, this book covers the latest advances in the field. The step-by-step protocols and practical examples given for each method constitute practical advice for beginners and experts alike.
Protein Synthesis
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Author : Yoshito Kaziro
language : en
Publisher:
Release Date : 1972
Protein Synthesis written by Yoshito Kaziro and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972 with Science categories.
Chemical Protein Synthesis
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Author : Xuechen Li
language : en
Publisher: Springer Nature
Release Date : 2022-06-27
Chemical Protein Synthesis written by Xuechen Li and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-27 with Science categories.
This volume provides updated protocols for chemical protein synthesis. Chapters guide readers through development methods, strategies, and applications of protein chemical synthesis. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Chemical Protein Synthesis aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
Protein Synthesis And Ribosome Structure
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Author : Knud H. Nierhaus
language : en
Publisher: John Wiley & Sons
Release Date : 2009-07-10
Protein Synthesis And Ribosome Structure written by Knud H. Nierhaus and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-10 with Science categories.
Knud Nierhaus, who has studied the ribosome for more than 30 years, has assembled here the combined efforts of several scientific disciplines into a uniform picture of the largest enzyme complex found in living cells, finally resolving many decades-old questions in molecular biology. In so doing he considers virtually all aspects of ribosome structure and function -- from the molecular mechanism of different ribosomal ribozyme activities to their selective inhibition by antibiotics, from assembly of the core particle to the regulation of ribosome component synthesis. The result is a premier resource for anyone with an interest in ribosomal protein synthesis, whether in the context of molecular biology, biotechnology, pharmacology or molecular medicine.
Evolution Of The Protein Synthesis Machinery And Its Regulation
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Author : Greco Hernández
language : en
Publisher: Springer
Release Date : 2016-08-10
Evolution Of The Protein Synthesis Machinery And Its Regulation written by Greco Hernández and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-10 with Science categories.
The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.
Mechanisms Of Protein Synthesis
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Author : E. Bermek
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mechanisms Of Protein Synthesis written by E. Bermek and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This volume contains the papers presented at the international symposium on "Molecular Mechanisms in Protein Synthesis" held on September 26-27, 1983 at the Beyaz Ko§k in Emirgan, Bosphorus, Istanbul. The symposium aimed to create a medium for information exchange and discussions regarding the current developments in the area of protein syn thesis. To ensure an informal yet scientifically stimulating and productive atmosphere providing opportunity for relaxed and speculative discussions, the number of presentations was limited to twenty and that of attendants to about sixty. The emphasis in the symposium was laid on structure-function relations in the prokaryotic protein synthesizing systems and on the control mechanisms of eukaryotic protein synthesis, in particular, during chain initia tion. Other issues like evolutionary aspects of protein synthesis, translational components genes and proofreading were covered as well. The manuscripts represent the extended accounts of the oral presenta tions, and it has been aimed with the concluding remarks at the end of the volume to give a summarizing view of the presentations and the discussions.
Protein Synthesis
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Author : Abraham K. Abraham
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Protein Synthesis written by Abraham K. Abraham and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
During the past decade we have witnessed several major dis coveries in the area of protein synthesis and post-translational modification of protein molecules. In this volume, many of the lat est research developments in these fields are reported by the dis tinguished international group of scientists who presented their state-of-the-art results at the 13th Linderstr0m-Lang Conference held at God0Ysund, Norway, June 14-18, 1983. We feel that the presentation here of so wide a variety of articles on both the molecular and the cellular aspects of protein synthesis will be of considerable value to many scientists working in the area who were unable to attend, as well as to many who are active in related areas. In addition to the research papers, the contents of the six scientific sessions held during the conference have been summarized by the respective session chairmen. These individual summaries provide insightful syntheses of all the recent progress in each field, identify which current problems remain of special inter est, and suggest what the future may hold in the several areas of protein synthesis research covered. Though this volume obviously cannot provide a complete survey of all important ongoing research on the molecular and cellular biology of translational and post-translational events, we are confi dent that it will facilitate a much better understanding of many im portant contemporary problems in research on protein synthesis, including cell differentiation, translational accuracy, protein modifi cation, intracellular transport, and membrane turnover.
Protein Synthesis And Targeting In Yeast
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Author : Alistair J.P. Brown
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Protein Synthesis And Targeting In Yeast written by Alistair J.P. Brown and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
Due to fundamental similarities between the yeast Saccharomyces cerevisiae and multicellular organisms at the molecular level, and the powerful range of experimental tools available for this yeast, S. cerevisiae is proving an ideal model system for studies on protein synthesis and targeting. The topics covered are: - Messenger RNA stability and translation.- The translation apparatus. - Translational control andfidelity. - Protein targeting to the mitochondrion. - Nuclear transport. - The secretory pathway. - Protein folding and degradation. - Protein splicing. Modern and often novel molecular, genetic and biochemical approaches as well as most recent data are provided. The reader will gain a comprehensive view of the current status of the field.
Total Chemical Synthesis Of Proteins
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Author : Ashraf Brik
language : en
Publisher: John Wiley & Sons
Release Date : 2021-02-23
Total Chemical Synthesis Of Proteins written by Ashraf Brik and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-23 with Science categories.
How to synthesize native and modified proteins in the test tube With contributions from a panel of experts representing a range of disciplines, Total Chemical Synthesis of Proteins presents a carefully curated collection of synthetic approaches and strategies for the total synthesis of native and modified proteins. Comprehensive in scope, this important reference explores the three main chemoselective ligation methods for assembling unprotected peptide segments, including native chemical ligation (NCL). It includes information on synthetic strategies for the complex polypeptides that constitute glycoproteins, sulfoproteins, and membrane proteins, as well as their characterization. In addition, important areas of application for total protein synthesis are detailed, such as protein crystallography, protein engineering, and biomedical research. The authors also discuss the synthetic challenges that remain to be addressed. This unmatched resource: Contains valuable insights from the pioneers in the field of chemical protein synthesis Presents proven synthetic approaches for a range of protein families Explores key applications of precisely controlled protein synthesis, including novel diagnostics and therapeutics Written for organic chemists, biochemists, biotechnologists, and molecular biologists, Total Chemical Synthesis of Proteins provides key knowledge for everyone venturing into the burgeoning field of protein design and synthetic biology.