Proteogenomics

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Proteogenomics

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Author : Jens Allmer
language : en
Publisher: Springer Nature
Release Date : 2024-10-22

Proteogenomics written by Jens Allmer and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-22 with Computers categories.

This volume presents an up-to-date overview of the current state-of-the-art protocols, and aims to put proteogenomics into a broader perspective. The chapters in this book detail methods and techniques ranging from mass spectrometry to proteomics and proteogenomics and their biomedical implications and applications. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. A highlight for everyone new to the field are the chapters, which put proteogenomics to use to answer biomedical questions. Authoritative and accessible, Proteogenomics: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Proteogenomics

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Author : Ákos Végvári
language : en
Publisher: Springer
Release Date : 2016-09-29

Proteogenomics written by Ákos Végvári and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-29 with Science categories.

This book highlights key technologies and identifies areas for further development in proteogenomics. The utility and usefulness of very large Omics data sets (Next Gen Sequencing of DNA, RNA-seq, ribosome profiling, mass spectrometry- and antibody-based proteomics) is discussed and opportunities and challenges of related bioinformatics applications are outlined. The reader will be able to appreciate the interdisciplinary nature of the continuously evolving area of proteogenomics, which has already grown beyond its original concept of verifying gene annotations by proteomics. The chapters presented in this book are arranged to offer a general overview, rather than to provide detailed descriptions of technologies. The selected applications will provide useful insight into the level of detail that can be obtained in relation to certain diseases areas, including cancer biology and personalized medicine. The readers will find that each chapter delivers a comprehensive approach to proteogenomics, each from the point of view of a specific application. Research scientists interested in innovative processes that can offer a unique and at the same time a more complete access to technological developments and concepts that in turn can contribute to a better understand biological functions should read this book.

Proteomics In Biology Part A

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Author :
language : en
Publisher: Academic Press
Release Date : 2017-01-19

Proteomics In Biology Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-19 with Science categories.

Proteomics in Biology Part A, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field, and a focus on proteomics for this updated volume. - Continues the legacy of this premier serial with quality chapters that focus on proteomics - Contains contributions from leading authorities

Translational Research In Breast Cancer

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Author : Dong-Young Noh
language : en
Publisher: Springer Nature
Release Date : 2021-05-13

Translational Research In Breast Cancer written by Dong-Young Noh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-13 with Medical categories.

This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention is devoted to breast cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in breast cancer. Various patient-derived research models are discussed, and a further focus is the role of biomarkers in precision medicine for breast cancer patients. Next-generation clinical research receives detailed attention, addressing the increasingly important role of big data in breast cancer research and a wide range of other emerging developments. An entire section is also devoted to the management of women with high-risk breast cancer. Translational Research in Breast Cancer will help clinicians and scientists to optimize their collaboration in order to achieve the common goal of conquering breast cancer.

Advanced Vaccination Technologies For Infectious And Chronic Diseases

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Author : Vasso Apostolopoulos
language : en
Publisher: Elsevier
Release Date : 2024-03-25

Advanced Vaccination Technologies For Infectious And Chronic Diseases written by Vasso Apostolopoulos and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-25 with Medical categories.

The role of vaccines is emerging and even critical to ending infectious and chronic diseases and pandemics alike. The design and development of new vaccines could lead to improved health. Handbook on Advanced Vaccination Technologies for Infectious and Chronic Disease discusses these new developments and introduces the reader to the current state of the science and the outlook going forward from the discovery of vaccines to the clinical trials of personalized vaccines. Handbook on Advanced Vaccination Technologies for Infectious and Chronic Diseases is a valuable reference for occupational health professionals whose role involves supervision of immunization programs such as those working in the National Health Service, some sectors of higher education and the pharmaceutical industry. - Offers comprehensive coverage of different vaccine platforms and their development - Includes information on the regulatory perspective of vaccine development - Describes different delivery approaches for vaccinology - Explains the clinical development of vaccines along with novel platforms - Covers all recent developments of vaccine production technologies, new types of vaccines, and ongoing research that could prevent future pandemics

Plant Stress Tolerance

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Author : Kareem A. Mosa
language : en
Publisher: Springer
Release Date : 2017-06-24

Plant Stress Tolerance written by Kareem A. Mosa and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-24 with Science categories.

Providing a comprehensive overview of cutting-edge research on Omics applications in plant sciences field,“Plant Stress Tolerance” focuses on different approaches towards plant stress tolerance including both biotic stresses and abiotic stresses. This book outlines the challenges facing this area of research, with solid, up-to-date information for graduate students, academic scientists and researchers on using the recent advances of Omics technologies on plant stresses.

Aacr 2016 Abstracts 2697 5293

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Author : American Association for Cancer Research (AACR)
language : en
Publisher: CTI Meeting Technology
Release Date : 2016-03-28

Aacr 2016 Abstracts 2697 5293 written by American Association for Cancer Research (AACR) and has been published by CTI Meeting Technology this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-28 with Medical categories.

The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 2697-5293 presented on April 19-20, 2016, at the AACR Annual Meeting.

Maldi Tof And Tandem Ms For Clinical Microbiology

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Author : Haroun N. Shah
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-30

Maldi Tof And Tandem Ms For Clinical Microbiology written by Haroun N. Shah and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-30 with Science categories.

This book highlights the triumph of MALDI-TOF mass spectrometry over the past decade and provides insight into new and expanding technologies through a comprehensive range of short chapters that enable the reader to gauge their current status and how they may progress over the next decade. This book serves as a platform to consolidate current strengths of the technology and highlight new frontiers in tandem MS/MS that are likely to eventually supersede MALDI-TOF MS. Chapters discuss: Challenges of Identifying Mycobacterium to the Species level Identification of Bacteroides and Other Clinically Relevant Anaerobes Identification of Species in Mixed Microbial Populations Detection of Resistance Mechanisms Proteomics as a biomarker discovery and validation platform Determination of Antimicrobial Resistance using Tandem Mass Spectrometry

Microbiological Activity For Soil And Plant Health Management

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Author : Ravindra Soni
language : en
Publisher: Springer Nature
Release Date : 2021-11-24

Microbiological Activity For Soil And Plant Health Management written by Ravindra Soni and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-24 with Science categories.

Plants and the soil they grow in, are confronted with severe biotic and abiotic stresses viz. nutrient starvation, salt stress, drought, flooding, xenobiotic contamination, in order to sustain in an ecosystem. They also shape the microbial composition in their vicinity by modulating their secretions. This book discusses the pressing demand for novel and potential microorganisms to support an environment-friendly and cost-effective way of stress management in the plants. The book summarizes the processes and mechanisms involved in microbe-assisted plant and soil stress management. It discusses the challenges and opportunities in the application of microbial interactions in plant health. It describes in detail the nutrient dynamics of different soil systems. It includes important topics like agriculturally important genes and enzymes, rhizosphere modeling & engineering, genetically engineered bio-inoculants etc. It also talks about the application of next-generation technologies, omics and nano-based technologies. In the recent years, more than 50% of agricultural production relies on chemical fertilizers, leading to serious health issues and environmental concerns. This book provides natural solutions to these environmental concerns. This book is useful for researchers and students in the field of microbiology, agriculture, soil biology and plant sciences.

Proteome Informatics

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Author : Conrad Bessant
language : en
Publisher: Royal Society of Chemistry
Release Date : 2016-11-15

Proteome Informatics written by Conrad Bessant and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-15 with Science categories.

The field of proteomics has developed rapidly over the past decade nurturing the need for a detailed introduction to the various informatics topics that underpin the main liquid chromatography tandem mass spectrometry (LC-MS/MS) protocols used for protein identification and quantitation. Proteins are a key component of any biological system, and monitoring proteins using LC-MS/MS proteomics is becoming commonplace in a wide range of biological research areas. However, many researchers treat proteomics software tools as a black box, drawing conclusions from the output of such tools without considering the nuances and limitations of the algorithms on which such software is based. This book seeks to address this situation by bringing together world experts to provide clear explanations of the key algorithms, workflows and analysis frameworks, so that users of proteomics data can be confident that they are using appropriate tools in suitable ways.