Proteomic Profiling
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Proteomic Profiling And Analytical Chemistry
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Author : Pawel Ciborowski
language : en
Publisher: Elsevier
Release Date : 2016-03-02
Proteomic Profiling And Analytical Chemistry written by Pawel Ciborowski and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-02 with Science categories.
Proteomic Profiling and Analytical Chemistry: The Crossroads, Second Edition helps scientists without a strong background in analytical chemistry to understand principles of the multistep proteomic experiment necessary for its successful completion. It also helps researchers who do have an analytical chemistry background to break into the proteomics field. Highlighting points of junction between proteomics and analytical chemistry, this resource links experimental design with analytical measurements, data analysis, and quality control. This targeted point of view will help both biologists and chemists to better understand all components of a complex proteomic study. The book provides detailed coverage of experimental aspects such as sample preparation, protein extraction and precipitation, gel electrophoresis, microarrays, dynamics of fluorescent dyes, and more. The key feature of this book is a direct link between multistep proteomic strategy and quality control routinely applied in analytical chemistry. This second edition features a new chapter on SWATH-MS, substantial updates to all chapters, including proteomic database search and analytical quantification, expanded discussion of post-hoc statistical tests, and additional content on validation in proteomics. - Covers the analytical consequences of protein and peptide modifications that may have a profound effect on how and what researchers actually measure - Includes practical examples illustrating the importance of problems in quantitation and validation of biomarkers - Helps in designing and executing proteomic experiments with sound analytics
Proteomic Profiling And Analytical Chemistry
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Author : Pawel Ciborowski
language : en
Publisher: Newnes
Release Date : 2012-12-31
Proteomic Profiling And Analytical Chemistry written by Pawel Ciborowski and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Science categories.
Proteomic Profiling and Analytical Chemistry helps scientists without a strong background in analytical chemistry to understand basic analytical principles and apply them to proteomics profiling. In most proteomic profiling experiments, liquid chromatography is used; this method is also used widely in analytical chemistry. This book bridges the gap between overly specialized courses and books in mass spectrometry, proteomics and analytical chemistry. It also helps researchers with an analytical chemistry background to break into the proteomics field. Proteomic Profiling and Analytical Chemistry focuses on practical applications for proteomic research helping readers to design better experiments and to more easily interpret, analyze and validate the resulting data. Experimental aspects such as sample preparation, protein extraction and precipitation, gel electrophoresis, microarrays, dynamics of fluorescent dyes, and more are all covered in detail. - Covers the analytical consequences of protein and peptide modifications that may have a profound effect on how and what researchers actually measure - Includes practical examples illustrating the importance of problems in quantitation and validation of biomarkers - Helps in designing and executing proteomic experiments with sound analytics
Proteomic Profiling
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Author : Anton Posch
language : en
Publisher: Humana
Release Date : 2021-02-04
Proteomic Profiling written by Anton Posch and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-04 with Science categories.
This detailed new edition presents the latest developments of the main pillars of protein analysis, namely sample preparation, separation, and characterization. Core areas in this volume are protocols for the analysis of post-translational modifications and protein interaction partners, followed by sophisticated procedures to enrich for extracellular vesicles and organelles, along with several types of protein immuno-assays complemented by various methods for the characterization of antibodies and host-cell protein analysis. Last but not least, a few standard sample preparation protocols and recent advances concerning immuno-chemical detection of proteins are included as well. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Proteomic Profiling: Methods and Protocols, Second Edition serves as an ideal reference for students of biochemistry, biomedicine, biology, and genomics and will be an invaluable source for the experienced, practicing scientist as well.
Development Of Proteomic Profiling Methods For Analysis Of Human Cancer Proteomes
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Author : Paweena Kreunin
language : en
Publisher:
Release Date : 2006
Development Of Proteomic Profiling Methods For Analysis Of Human Cancer Proteomes written by Paweena Kreunin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.
Proteomics Today
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Author : Mahmoud H. Hamdan
language : en
Publisher: John Wiley & Sons
Release Date : 2005-05-13
Proteomics Today written by Mahmoud H. Hamdan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-13 with Science categories.
The last few years have seen an unprecedented drive toward theapplication of proteomics to resolving challenging biomedical andbiochemical tasks. Separation techniques combined with modern massspectrometry are playing a central role in this drive. This bookdiscusses the increasingly important role of mass spectrometry inproteomic research, and emphasizes recent advances in the existingtechnology and describes the advantages and pitfalls as well. * Provides a scientifically valid method for analyzing theapproximatey 500,000 proteins that are encoded in the humangenome * Explains the hows and whys of using mass spectrometry inproteomic analysis * Brings together the latest approaches combining separationtechniques and mass spectrometry and their application in proteomeanalysis * Comments on future challenges and how they may be addressed * Includes sections on troubleshooting
Proteomics Technologies And Applications
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Author : Ibrokhim Y. Abdurakhmonov
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-09-25
Proteomics Technologies And Applications written by Ibrokhim Y. Abdurakhmonov and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-25 with Science categories.
Proteomics Technologies and Applications reviews and describes the nature and application of molecules with proteins or peptides, and elucidates and predicts the possible molecular and physiological causes related to changing proteomic profiles. Chapters target various methods and tools available for analysis, detection, separation, quantification, and localization of cell proteomes of a biological system, which are helpful as biomarkers for various disease prognoses and diagnoses.
Proteomics
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Author : Shafat Ali
language : en
Publisher: Elsevier
Release Date : 2023-02-14
Proteomics written by Shafat Ali and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-14 with Science categories.
Proteomics: A Promising Approach for Cancer Research provides an updated overview of scientific knowledge, achievements and findings in the field of cancer proteomics. The book discusses topics such as the use of proteomics in cancer biology and drug discovery, its role in surgical oncology, applications of mass spectrometry, target proteomics, single-cell proteomics, and next-generation proteomics. In addition, it discusses proteomics and phosphor-proteomics in cancer precision medicine; translation of proteomics research into clinical application; and challenges and future developments of the field. This will be a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical field who are interested in the potential of proteomics in cancer research and treatment. The field of cancer proteomics is very dynamic, with emerging trends related to clinical solutions developed in recent years, therefore this book's content helps readers get up-to-speed on the topic to easily apply learnings into their research or clinical practice. - Provides up-to-date information on current cancer proteomics research developed globally - Presents basic research aspects to clinical implications of proteomics on cancer diagnosis and potential treatments - Discusses challenges and future developments of the field to leverage further research and applicability in clinical setting
Proteome Research
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Author : M.R. Wilkins
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-11
Proteome Research written by M.R. Wilkins and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-11 with Science categories.
Proteomics is a multifaceted, interdisciplinary field which studies the complexity and dynamics of proteins in biological systems. It combines powerful separation and analytical technology with advanced informatics to understand the function of proteins in the cell and in the body. This book provides a clear conceptual description of each facet of proteomics, describes recent advances in technology and thinking in each area, and provides details of how these have been applied to a variety of biological problems. It is written by expert practitioners in the field, from industry, research institutions, and the clinic. It provides junior and experienced researchers with an invaluable proteomic reference, and gives fascinating glimpses of the future of this dynamic field.
Proteomic Profiling Of Saliva For The Detection Of Cancer
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Author : Prasanna Ramachandran
language : en
Publisher:
Release Date : 2009
Proteomic Profiling Of Saliva For The Detection Of Cancer written by Prasanna Ramachandran and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Clinical Proteomics
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Author : Jennifer E. Van Eyk
language : en
Publisher: John Wiley & Sons
Release Date : 2008-09-08
Clinical Proteomics written by Jennifer E. Van Eyk and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-08 with Science categories.
Unparalleled in its scope and depth, this book brings together proteomic approaches in diagnosis and treatment from all clinical fields, including clinical toxicology. The result is a new discipline in molecular medicine that will revolutionize the treatment and prevention of cancer, stroke and other severe diseases. Following an overview of clinical proteomics, the authors look at the technologies available, before moving on to cancer, cardiopulmonary disease, diabetes and stroke. A whole section is devoted to toxicity and the work is rounded off with a discussion of the future of clinical proteomics.