Proteomics And Systems Biology
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Proteomics In Systems Biology
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Author : Jennifer Geddes-McAlister
language : en
Publisher: Springer Nature
Release Date : 2022-05-25
Proteomics In Systems Biology written by Jennifer Geddes-McAlister and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-25 with Science categories.
This detailed book highlights the diverse techniques and applications of proteomics in an accessible, informative, and concise manner. The collection features sample preparation from distinct extraction, quantification, enrichment, modification, as well as interactome methodology for the in-depth exploration of biological systems, and the application of proteomics to clinical, infectious disease, and agricultural practices. Moreover, cutting-edge bioinformatics tools, encompassing machine learning and data integration strategies, are explored, as are techniques expanding beyond proteomics into the realm of metabolomics. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting known pitfalls. Comprehensive and practical, Proteomics in Systems Biology: Methods and Protocols emphasizes the importance of proteomics and demonstrates a plethora of approaches for investigating diverse biological entities from a systems perspective.
Proteomics And Systems Biology
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-07-30
Proteomics And Systems Biology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-30 with Science categories.
Proteomics and Systems Biology, Volume 127 in the Advances in Protein Chemistry and Structural Biology series, outlines current proteomic methodologies and discuss the challenges in future applications of systems biology in a number of biomedical/bioscience subjects. In last few decades, advances in genomics, proteomics, metabolomics, glycomics, venomics, etc., have produced vast large-scale datasets that need to be analyzed with a single main objective of understanding biological systems as a whole. Such understanding will allow us to predict and characterize the dynamic properties of biological systems. Integrates experimental and computational methods for understanding biological systems as a whole Contains timely chapters written by well-renowned authorities in their field Includes well supported content that is accompanied by a number of high-quality illustrations, figures and tables, hence it targets a wide audience of specialists, researchers and students
Proteomics In Domestic Animals From Farm To Systems Biology
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Author : Andre Martinho de Almeida
language : en
Publisher: Springer
Release Date : 2018-02-01
Proteomics In Domestic Animals From Farm To Systems Biology written by Andre Martinho de Almeida and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-01 with Science categories.
Proteomics, like other post-genomics tools, has been growing at a rapid pace and has important applications in numerous fields of science. While its use in animal and veterinary sciences is still limited, there have been considerable advances in this field in recent years, in areas as diverse as physiology, nutrition and food of animal origin processing. This is mainly as a consequence of a wider availability and better understanding of proteomics methodologies by animal and veterinary researchers. This book provides a comprehensive, state-of-the-art account of the status of farm-animal proteomics research, focusing on the principles behind proteomics methodologies and its specific applications and offering clear example.
Systems Biology And Computational Proteomics
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Author : Trey Ideker
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-07-20
Systems Biology And Computational Proteomics written by Trey Ideker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-20 with Science categories.
This book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2006 satellite events: the Second Annual Workshop on Systems Biology, RSB 2006, and the First Biennial Workshop on Computational Proteomics, RCP 2006, held in San Diego, CA, USA in December 2006. The papers cover various aspects of systems biology and explore the use of computational mass spectrometry in various proteomic applications.
Omics Applications For Systems Biology
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Author : Wan Mohd Aizat
language : en
Publisher: Springer
Release Date : 2018-10-31
Omics Applications For Systems Biology written by Wan Mohd Aizat and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-31 with Science categories.
This book explains omics at the most basic level, including how this new concept can be properly utilized in molecular and systems biology research. Most reviews and books on this topic have mainly focused on the technicalities and complexity of each omics’ platform, impeding readers to wholly understand its fundamentals and applications. This book tackles such gap and will be most beneficial to novice in this area, university students and even researchers. Basic workflow and practical guidance in each omics are also described, such that scientists can properly design their experimentation effectively. Furthermore, how each omics platform has been conducted in our institute (INBIOSIS) is also detailed, a comprehensive example on this topic to further enhance readers’ understanding. The contributors of each chapter have utilized the platforms in various manner within their own research and beyond. The contributors have also been interactively integrated and combined these different omics approaches in their research, being able to systematically write each chapter with the conscious knowledge of other inter-relating topics of omics. The potential readers and audience of this book can come from undergraduate and postgraduate students who wish to extend their comprehension in the topics of molecular biology and big data analysis using omics platforms. Furthermore, researchers and scientists whom may have expertise in basic molecular biology can extend their experimentation using the omics technologies and workflow outlined in this book, benefiting their research in the long run.
Methods For Large Scale Quantitative Proteomics In Systems Biology
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Author : Elyse Freiberger
language : en
Publisher:
Release Date : 2018
Methods For Large Scale Quantitative Proteomics In Systems Biology written by Elyse Freiberger and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
The research described in this dissertation presents strategies for acquiring high quality large-scale mass spectrometry-based quantitative proteomics data that have been applied to model systems as diverse as Brewers' yeast, cultured mammalian cells, and isolated murine pancreatic islets. Background on proteomics technologies, an overview of the requirements for quantitative proteomics experiments, and major concerns specific to proteomics on a large scale are presented in Chapter 1. A study of valosin-containing protein interactors using size-exclusion chromatography and a novel quantification scheme is described in Chapter 2. A comprehensive analysis of 174 single-gene deletion yeast strains wherein proteomic data is integrated with metabolic and lipidomic results is described in Chapter 3. In Chapter 4, pancreatic islet proteomes across eight inbred laboratory mouse strains are quantified and the data are correlated with phenotypic information and ex vivo insulin secretion results. Chapter 5 details method optimization and analysis of 383 mouse islet proteomes using the diversity outbred mouse resource for the largest protein quantitative trait locus mapping study completed to date.
New Frontiers Of Network Analysis In Systems Biology
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Author : Avi Ma'ayan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-06-25
New Frontiers Of Network Analysis In Systems Biology written by Avi Ma'ayan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-25 with Medical categories.
The rapidly developing field of systems biology is influencing many aspects of biological research and is expected to transform biomedicine. Some emerging offshoots and specialized branches in systems biology are receiving particular attention and are becoming highly active areas of research. This collection of invited reviews describes some of the latest cutting-edge experimental and computational advances in these emerging sub-fields of systems biology. In particular, this collection focuses on the study of mammalian embryonic stem cells; new technologies involving mass-spectrometry proteomics; single cell measurements; methods for modeling complex stochastic systems; network-based classification algorithms; and the revolutionary emerging field of systems pharmacology.
Subcellular Proteomics
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Author : Eric Bertrand
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-29
Subcellular Proteomics written by Eric Bertrand and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-29 with Science categories.
This volume summarizes the new developments that made subcellular proteomics a rapidly expanding area. It examines the different levels of subcellular organization and their specific methodologies. In addition, the book includes coverage of systems biology that deals with the integration of the data derived from these different levels to produce a synthetic description of the cell as a system.
Systems Biology And Computational Proteomics
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Author : Trey Ideker
language : en
Publisher: Springer
Release Date : 2009-09-02
Systems Biology And Computational Proteomics written by Trey Ideker and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-02 with Science categories.
This book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2006 satellite events: the Second Annual Workshop on Systems Biology, RSB 2006, and the First Biennial Workshop on Computational Proteomics, RCP 2006, held in San Diego, CA, USA in December 2006. The papers cover various aspects of systems biology and explore the use of computational mass spectrometry in various proteomic applications.
Knowledge Discovery In Proteomics
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Author : Igor Jurisica
language : en
Publisher: CRC Press
Release Date : 2005-09-02
Knowledge Discovery In Proteomics written by Igor Jurisica and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-02 with Computers categories.
Multi-modal representations, the lack of complete and consistent domain theories, rapid evolution of domain knowledge, high dimensionality, and large amounts of missing information - these are challenges inherent in modern proteomics. As our understanding of protein structure and function becomes ever more complicated, we have reached a point where