Proteomics In Functional Genomics
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Proteomics In Functional Genomics
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Author : P. Jolles
language : en
Publisher: Birkhäuser
Release Date : 2013-03-11
Proteomics In Functional Genomics written by P. Jolles and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-11 with Science categories.
A wealth of information has accumulated over the last few years on the human genome. The new insights have completely changed the focus of protein analysis. It is no longer time-consuming analysis of unknown products, but rather selective identifications of individual forms, modifications and processings, and overall analysis of global protein outputs from cells and tissues in health and disease. This book gears to the rising need of sensitive, accurate, and fast separation and identification techniques in proteomics. It discusses current methodologies of modern protein analysis, from isolation and sample preparation, over analysis and identification, to final characterization. Several evaluations concentrate on the now productive approaches of two-dimensional gel electrophoresis and mass spectrometry, but alternative methods and further perspectives are also outlined. The book includes an overlook over current databases to connect protein analysis data with all available information,...
Proteome Research
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Author : Marc R. Wilkins
language : en
Publisher: Springer Science & Business Media
Release Date : 1997
Proteome Research written by Marc R. Wilkins and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.
Introduction to the proteome (K. L. Williams, D. F. Hochstrasser). Two-dimensional electrophoresis: the state of the art and future directions (B. R. Herbert, J.-C. Sanchez, L. Bini). large-scale comparative protein modeling ( M. C. Peitsch, N. Guex); Clinical and biomedical applications of proteomics (D. F. Hochstrasser). Biological applications of proteomics (K. L. Williams, V. Pallini). Conclusions (D. F. Hochstrasser, L. Williams). Index.
Genomics And Proteomics
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Author : Sándor Suhai
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-08
Genomics And Proteomics written by Sándor Suhai and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-08 with Science categories.
Genome research will certainly be one of the most important and exciting sci- tific disciplines of the 21st century. Deciphering the structure of the human genome, as well as that of several model organisms, is the key to our understanding how genes fu- tion in health and disease. With the combined development of innovativetools, resources, scientific know-how, and an overall functional genomic strategy, the origins of human and other organisms’geneticdiseases can be traced. Scientificresearch groups and dev- opmental departments of several major pharmaceutical and biotechnological companies are using new, innovative strategies to unravel how genes function, elucidating the gene protein product, understanding how genes interact with others-both in health and in the disease state. Presently, the impact of the applications of genome research on our society in medicine, agriculture and nutrition will be comparable only to that of communication technologies. In fact, computational methods, including networking, have been playing a substantial role even in genomics and proteomics from the beginning. We can observe, however, a fundamental change of the paradigm in life sciences these days: research focused until now mostly on the study of single processes related to a few genes or gene products, but due to technical developments of the last years we can now potentially identify and analyze all genes and gene products of an organism and clarify their role in the network of lifeprocesses.
Functional Genomics And Proteomics In The Clinical Neurosciences
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Author : Scott E. Hemby
language : en
Publisher: Elsevier
Release Date : 2006-10-09
Functional Genomics And Proteomics In The Clinical Neurosciences written by Scott E. Hemby and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-09 with Science categories.
The purpose of this work is to familiarize neuroscientists with the available tools for proteome research and their relative abilities and limitations. To know the identities of the thousands of different proteins in a cell, and the modifications to these proteins, along with how the amounts of both of these change in different conditions would revolutionize biology and medicine. While important strides are being made towards achieving the goal of global mRNA analysis, mRNA is not the functional endpoint of gene expression and mRNA expression may not directly equate with protein expression. There are many potential applications for proteomics in neuroscience: determination of the neuro-proteome, comparative protein expression profiling, post-translational protein modification profiling and mapping protein-protein interactions, to name but a few. Functional Genomics and Proteomics in Clinical Neuroscience will comment on all of these applications, but with an emphasis on protein expression profiling. This book combines the basic methodology of genomics and proteomics with the current applications of such technologies in understanding psychiatric illnesses. * Introduction of basic methodologies in genomics and proteomics and their integration in psychiatry* Development of the text in sections related to methods, application and future directions of these rapidly advancing technologies* Use of actual data to illustrate many principles of functional genomics and proteomics. * Introduction to bioinformatics and database management techniques
Functional Genomics And Proteomics
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Author : Charles Malkoff
language : en
Publisher:
Release Date : 2016-05-31
Functional Genomics And Proteomics written by Charles Malkoff and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-31 with Science categories.
Functional genomics and proteomics play a crucial role in analysing available genetic data and gathering key information for further use. The book emphasizes on the dynamic aspects of genomics and proteomics such as regulation of genes, transcription, translation and protein-protein interactions, large scale protein structures, etc. Researches and case-studies included in this book attempt to provide methods, models and techniques to analyze and gather information from large pool of available genomic data of various organisms. This book provides a detailed explanation on structure determination and structural genomics. Students and researchers will find this book beneficial.
Bioinformatics Proteomics And Functional Genomics
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Author : American Institute of Chemical Engineers
language : en
Publisher:
Release Date : 2002
Bioinformatics Proteomics And Functional Genomics written by American Institute of Chemical Engineers and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.
Yeast Functional Genomics
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Author : Frédéric Devaux
language : en
Publisher: Springer Nature
Release Date : 2022-05-06
Yeast Functional Genomics written by Frédéric Devaux and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-06 with Science categories.
This second edition volume discusses the latest techniques and protocols used in the field that were not covered in the previous edition. The chapters in this book are organized into five parts. Part One looks at transcriptomic analyses and Part Two covers DNA replication and protein/DNA interactions. Part Three discusses translation dynamics, protein complexes, and proteomics. Part Four looks at genotypic screens and phenotypic profiling, and Part Five explores in silico integration of functional genomics data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary material and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and practical, Yeast Functional Genomics: Methods and Protocols, Second Edition is a valuable resource for all researchers interested in learning more about the evolving field of yeast. Chapters 1, 9, 16, 20, 22, 24, and 25 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Functional Genomics
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Author : Michael J. Brownstein
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-03
Functional Genomics written by Michael J. Brownstein and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-03 with Science categories.
This collection of robust, readily reproducible methods for microarray-based studies includes expert guidance in the optimal data analysis and informatics. On the methods side are proven techniques for monitoring subcellular RNA localization en masse, for mapping chromosomes at the resolution of a single gene, and for surveying the steady-state genome-wide distribution of DNA binding proteins in vivo. For those workers dealing with massive data sets, the book discusses the methodological aspects of data analysis and informatics in the design of microarray experiments, the choice of test statistic, and the assessment of observational significance, data reduction, and clustering.
Bioinformatics And Functional Genomics
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Author : Jonathan Pevsner
language : en
Publisher: John Wiley & Sons
Release Date : 2005-03-04
Bioinformatics And Functional Genomics written by Jonathan Pevsner and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-03-04 with Science categories.
Wiley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key techniques and math/stats principles, Summary, Recommended Reading list, and URLs for freely available software. The text is suitable for professionals and students at every level, including those with little to no background in computer science.
Yeast Functional Genomics And Proteomics
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Author : Igor Stagljar
language : en
Publisher: Humana Press
Release Date : 2014-11-26
Yeast Functional Genomics And Proteomics written by Igor Stagljar and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-26 with Science categories.
Given the popularity and utility of Saccharomyces cerevisiae, yeast-based functional genomics and proteomics technologies, developed over the past decade, have contributed greatly to our understanding of bacterial, yeast, fly, worm and human gene functions. In Yeast Functional Genomics and Proteomics: Methods and Protocols, experts in the field contribute stand-alone protocols suitable for daily use in research laboratories. The volume examines methods from the most major and fundamental techniques to more cutting-edge, advanced concepts. As part of the highly successful Methods in Molecular BiologyTM series, the chapters are clearly formatted with introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Yeast Functional Genomics and Proteomics: Methods and Protocols is an ideal reference for both yeast researchers and those who wish to use yeast as a model system for the further study of functional genomics and proteomics.