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Proteomics In Nephrology

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Proteomics In Nephrology

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Author : Visith Thongboonkerd
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2008

Proteomics In Nephrology written by Visith Thongboonkerd and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.

Since the publication of the first volume on proteomics in nephrology, methodologies and protocols for renal and urinary proteome analyses have been continuously improved, resulting in considerable progress towards clinical application. Proteomics not only contributes to a better understanding of the renal physiology and pathogenic mechanisms of kidney diseases, but also assists in the search for novel biomarkers for diagnostics and prognostics and supports the definition and development of new therapeutic targets and drugs for better therapeutic outcome. While the first volume focused mainly on an overview, technologies and methodologies, this volume highlights successful applications of proteomics to several kidney diseases, including acute kidney injury, nephrotic syndrome, diabetic nephropathy, renal allograft rejection, renal cell carcinoma, obstructive nephropathy, kidney stone disease, uremia, and others. Written by acclaimed experts in proteomics and nephrology, this book is an excellent resource of references for nephrologists, clinicians, pharmacists, other healthcare professionals, proteomists, physiologists, scientists, and trainees.

Proteomics In Nephrology

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Author : V. Thongboonkerd
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2004-07

Proteomics In Nephrology written by V. Thongboonkerd and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-07 with Medical categories.

The novel discipline of proteomics has experienced a rapid growth in the recent past and has a great potential for the future. Involving several fields, it offers various advantages: The study of proteins on a genomic scale allows to examine a large number of them simultaneously. Moreover, proteomic analysis provides information about post-translational modifications and functions of gene products or proteins that cannot be obtained by genomic analysis. The knowledge thus gained is also important for a better understanding of renal physiology and pathophysiology, to identify disease biomarkers, and to develop new target therapies. This book is the first one that applies the science of proteomics to nephrology: It sets out to give an overview of the discipline, providing detailed background information and outlining scope, advantages, and limitations of proteomics. The second section reviews principles of commonly used proteomic techniques, including sample preparation, two-dimensional gel electrophoresis, various types of mass spectrometry, expression proteomics, quantitative proteomics, practical bioinformatics, and clinical proteomics. In the last section, examples and perspectives are provided of how proteomics can be applied to various fields in nephrology, including nephrotoxicity, sodium transport, diabetic nephropathy, renal Fanconi syndrome, IgA nephropathy, physiology of podocytes and mesangial cells, hypertension, urological malignancies, and dialysis. The publication ends with a discussion of biomarker discovery in glomerular diseases and drug discovery. Written by acclaimed experts in both proteomics and nephrology, this truly remarkable book is essential reading for students, residents, fellows, scientists, and nephrologists who are interested in or devoted to research, as well as for general health professionals and clinicians.

Urine Proteomics In Kidney Disease Biomarker Discovery

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Author : Youhe Gao
language : en
Publisher: Springer
Release Date : 2014-10-29

Urine Proteomics In Kidney Disease Biomarker Discovery written by Youhe Gao and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-29 with Science categories.

This book systematically summarizes the ideas and technologies used in urine proteome analysis. It argues that change is the core of biomarker definition since the body uses its homeostatic mechanisms to correct changes in the blood. This means that urine is probably a better source of biomarkers than blood. A roadmap to the urinary biomarker era is proposed, and researchers are reminded of the potential opportunities and risks in their study design. Kidney diseases are emphasized as they produce the most significant changes in urine. This book tries to show researchers and graduate students, who are in or entering the field, "all things considered" rather than "the current affair".

Nephrology Hypertension Dialysis Transplantation

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Author : Thomas E. Andreoli
language : en
Publisher: Laszlo Rosivall
Release Date : 2006

Nephrology Hypertension Dialysis Transplantation written by Thomas E. Andreoli and has been published by Laszlo Rosivall this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.

Proteomics In Nephrology

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Author : V. Thongboonkerd
language : en
Publisher:
Release Date : 2008

Proteomics In Nephrology written by V. Thongboonkerd and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.

Renal And Urinary Proteomics

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Author : Visith Thongboonkerd
language : en
Publisher: John Wiley & Sons
Release Date : 2009-12-21

Renal And Urinary Proteomics written by Visith Thongboonkerd and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-21 with Science categories.

Auf der Grundlage der Resultate, die das internationale "Human Kidney and Urine Proteome Project" vorlegte, fasst dieser Band moderne Methoden und Protokolle für die Analyse von Nierengewebe und Urin des Menschen zusammen. Schritt für Schritt, ergänzt durch praxistaugliche Tipps und Hinweise für die Laborarbeit, werden Routinemethoden ebenso ausführlich vorgestellt wie Spezialverfahren für kompliziertere Proben oder Analyte.

Proteomics Of Human Body Fluids

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Author : Visith Thongboonkerd
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-01-23

Proteomics Of Human Body Fluids written by Visith Thongboonkerd and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-23 with Science categories.

This volume is the first collection of applications of proteomics to analyze various human body fluids. Proteomics of Human Bodyfluids consists of two parts. The first provides basic principles and strategies for proteomic analysis of human body fluids. The second offers more details regarding methodologies and recent findings and clinical applications of each specific type of human body fluids.

Biomarkers Of Kidney Disease

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Author : Charles L. Edelstein
language : en
Publisher: Academic Press
Release Date : 2010-10-27

Biomarkers Of Kidney Disease written by Charles L. Edelstein and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-27 with Science categories.

A biomarker is a molecule that is measured as a marker of normal biological processes, disease processes or the response to a diagnostic or therapeutic intervention. Kidney diseases like acute kidney injury, chronic kidney disease, diabetic nephropathy, glomerular disease, renal cancer and preeclampsia still have a high morbidity. Measurement of biomarkers in the blood or urine that detect patients at risk of kidney diseases or that detect kidney diseases in the earliest stage may ultimately result in preventative or earlier or more effective treatments for kidney diseases. Biomarkers of Kidney Disease reviews the basic and clinical research on biomarkers of the common kidney diseases including acute kidney injury, chronic kidney disease, renal cancer, diabetic nephropathy, glomerular disease and preeclampsia. The characteristics of an ideal biomarker of kidney diseases and statistical analysis of biomarker studies is detailed. The latest techniques for biomarker detection like metabolomics and proteomics is covered in the book. This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation and preeclampsia. - Presents a comprehensive, translational source for all aspects of renal biomarkers in one reference work - Experts in renal disease biomarkers (from all areas of academic and medical research) take readers from the bench research (cellular and molecular mechanism) to new therapeutic approaches

Issues In Kidney Disease Research And Treatment 2013 Edition

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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-05-01

Issues In Kidney Disease Research And Treatment 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-01 with Medical categories.

Issues in Kidney Disease Research and Treatment: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Nephrology. The editors have built Issues in Kidney Disease Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nephrology in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Kidney Disease Research and Treatment: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Diabetic Kidney

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Author : Pedro Cortes
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-06

The Diabetic Kidney written by Pedro Cortes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-06 with Medical categories.

A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.

Proteomics In Nephrology

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