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Proton Radiotherapy Accelerators


Proton Radiotherapy Accelerators
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Proton Radiotherapy Accelerators


Proton Radiotherapy Accelerators
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Author : Waldemar H Scharf
language : en
Publisher: World Scientific
Release Date : 2001-08-17

Proton Radiotherapy Accelerators written by Waldemar H Scharf and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-08-17 with Science categories.


Hadronic radiotherapy uses particle beams to treat tumors located near critical body structures and tumors that respond poorly to conventional photon and electron beam radiotherapy. Initial research in hadronic radiotherapy was performed using accelerators built for physics research. The good results of the proton and ion therapy programs have enhanced the tendency to use protontherapy as a routine method. There are about 20 working protontherapy facilities (first, second and third generation) and more than 30 centers are planned.This book presents the first comprehensive overview of the field with a discussion on the fundamental basis of particle physics and radiobiology, as well as review of clinical and technical specifications and designs for proton radiotherapy. In particular, the current designs of proton and heavy ion accelerators, beam delivery systems, gantries, beam monitoring and dosimetry systems, control and safety systems, patient positioning and immobilization devices, and ancillary treatment facilities are widely discussed.



Proton Beam Therapy


Proton Beam Therapy
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Author : Santosh Yajnik
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-10-17

Proton Beam Therapy written by Santosh Yajnik and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-17 with Medical categories.


Proton beam therapy is an emerging technology with promise of revolutionizing the treatment of cancer. While nearly half of all patients diagnosed with cancer in the US receive radiation therapy, the majority is delivered via electron accelerators, where photons are used to irradiate cancerous tissue. Because of the physical properties of photon beams, photons may deposit energy along their entire path length through the body. On the other hand, a proton beam directed at a tumor travels in a straight trajectory towards its target, gives off most of its energy at a defined depth called the Bragg peak, and then stops. While photons often deposit more energy within the healthy tissues of the body than within the cancer itself, protons can deposit most of their cancer-killing energy within the area of the tumor. As a result, in the properly selected patients, proton beam therapy has the ability to improve cure rates by increasing the dose delivered to the tumor and simultaneously reduce side-effects by decreasing the dose to surrounding tissue. The benefits of proton beam therapy in delivering a lethal hit to the target while sparing surrounding normal tissues from radiation are becoming applicable to an increasing number of patients and a growing list of conditions. In this book, the author will guide the reader through existing evidence supporting proton beam therapy for pediatric cancer, prostate cancer, lung cancer, brain tumors, spinal tumors, and several other conditions. The book will discuss which conditions are suitable for treatment with proton beam therapy, how the treatment is delivered, and the current data supporting its use.



Advances In Accelerators And Medical Physics


Advances In Accelerators And Medical Physics
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Author : Toshiyuki Shirai
language : en
Publisher: Academic Press
Release Date : 2023-05-25

Advances In Accelerators And Medical Physics written by Toshiyuki Shirai and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-25 with Science categories.


Radiotherapy is now one of the major cancer treatments. The field of accelerator and medical physics is important and growing to support high precision cancer radiotherapy. Advances in Accelerators and Medical Physics provides in-depth and comprehensive coverage of the basic concepts in x-ray therapy, electron beam therapy, particle therapy, boron neutron capture therapy, and molecular imaging and therapy. Novel technologies such as FLASH therapy and laser ion accelerator are also introduced. Each section of the book presents the current state of accelerators, irradiation methods and therapy technologies, as well as future trends in advanced research. This book will serve as a key resource for researchers and students to find all information on latest cancer radiotherapy technologies and methods. Offers a deep dive into fundamental accelerator and medical physics techniques and technologies used in cancer radiotherapy Considers updated status at hospitals and clinical facilities, and future research trends Covers advanced research, development and novel technologies Chapters written by experts from the Particle Accelerator Society of Japan(PASJ) and the Japan Society of Medical Physics (JSMP)



Proton Therapy Physics


Proton Therapy Physics
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Author : Harald Paganetti
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Proton Therapy Physics written by Harald Paganetti and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.


Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.



Reviews Of Accelerator Science And Technology


Reviews Of Accelerator Science And Technology
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Author : Alex Chao
language : en
Publisher: World Scientific
Release Date : 2009

Reviews Of Accelerator Science And Technology written by Alex Chao and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Medical categories.


Physical and biological basis of proton and of carbon ion radiation therapy and clinical outcome data / Herman Suit, Thomas F. Delaney and Alexei Trofimov -- The production of radionuclides for radiotracers in nuclear medicine / Thomas J. Ruth -- Proton radiation therapy in the hospital environment : conception, development, and operation of the initial hospital-based facility / James M. Slater, Jerry D. Slater and Andrew J. Wroe -- Microwave electron linacs for oncology / David H. Whittum -- Heavy-particle radiotherapy : system design and application / H. Tsujii, S. Minohara and K. Noda -- High frequency linacs for hadrontherapy / Ugo Amaldi, Saverio Braccini and Paolo Puggioni -- Medical cyclotrons / D.L. Friesel and T.A. Antaya -- Synchrotrons for hadrontherapy / Marco G. Pullia -- Beam delivery systems for particle radiation therapy : current status and recent developments / J.M. Schippers -- Laser acceleration of ions for radiation therapy / Toshiki Tajima, Dietrich Habs and Xueqing Yan -- FFAGs as accelerators and beam delivery devices for ion cancer therapy / Dejan Trbojevic -- The dielectric wall accelerator / George J. Caporaso, Yu-Jiuan Chen and Stephen E. Sampayan -- The supercollider : the Texas days - a personal recollection of its short life and demise / Stanley Wojcicki -- A man for all seasons : Robert R. Wilson / Edwin L. Goldwasser



Proton Therapy Physics Second Edition


Proton Therapy Physics Second Edition
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Author : Harald Paganetti
language : en
Publisher: CRC Press
Release Date : 2018-11-19

Proton Therapy Physics Second Edition written by Harald Paganetti and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-19 with Science categories.


Expanding on the highly successful first edition, this second edition of Proton Therapy Physics has been completely restructured and updated throughout, and includes several new chapters. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, this book provides an in-depth overview of the physics of this radiation therapy modality, eliminating the need to dig through information scattered across medical physics literature. After tracing the history of proton therapy, the book explores the atomic and nuclear physics background necessary for understanding proton interactions with tissue. The text then covers dosimetry, including beam delivery, shielding aspects, computer simulations, detector systems and measuring techniques for reference dosimetry. Important for daily operations, acceptance testing, commissioning, quality assurance and monitor unit calibrations are outlined. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. Imaging for treatment guidance as well as treatment monitoring is outlined. Finally, the biological implications of using protons from a physics perspective are discussed. This book is an ideal practical guide for physicians, dosimetrists, radiation therapists, and physicists who already have some experience in radiation oncology. It is also an invaluable reference for graduate students in medical physics programs, physicians in their last year of medical school or residency, and those considering a career in medical physics. Features: Updated with the latest technologies and methods in the field, covering all delivery methods of proton therapy, including beam scanning and passive scattering Discusses clinical aspects, such as treatment planning and quality assurance Offers insight on the past, present, and future of proton therapy from a physics perspective



Proton And Charged Particle Radiotherapy


Proton And Charged Particle Radiotherapy
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Author : Thomas F. De Laney
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2008

Proton And Charged Particle Radiotherapy written by Thomas F. De Laney and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.


This volume is the first comprehensive and practical clinical reference on proton and charged particle radiotherapy. The first half of the book explains the treatment delivery systems used, offers detailed guidance on treatment planning techniques, examines key clinical issues in proton radiotherapy, and reviews recent experience with heavier charged particle radiotherapy. The second half of the book offers "how-to" information on treatment of pediatric tumors, lymphomas, and tumors of the central nervous system, eye, skull base, cervical spine, bone and soft tissue, paranasal sinus, nasal cavity, nasopharynx, oropharynx, oral cavity, salivary glands, prostate, lung, gastrointestinal tract, female reproductive tract, and breast. More than 100 full-color illustrations complement the text.



Proton And Carbon Ion Therapy


Proton And Carbon Ion Therapy
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Author : C-M Charlie Ma
language : en
Publisher: CRC Press
Release Date : 2012-10-09

Proton And Carbon Ion Therapy written by C-M Charlie Ma and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-09 with Science categories.


Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy. The text also offers detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. After an overview, the book focuses on the fundamental aspects of proton and carbon ion therapy equipment, including accelerators, gantries, and delivery systems. It then discusses dosimetry, biology, imaging, and treatment planning basics and provides clinical guidelines on the use of proton and carbon ion therapy for the treatment of specific cancers. Suitable for anyone involved with medical physics and radiation therapy, this book offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and the future outlook of proton and carbon ion therapy. It presents a thorough introduction for those new to the field while providing a helpful, up-to-date reference for readers already using the therapy in clinical settings.



Proton Beam Radiotherapy


Proton Beam Radiotherapy
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Author : Koji Tsuboi
language : en
Publisher: Springer Nature
Release Date : 2020-01-24

Proton Beam Radiotherapy written by Koji Tsuboi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-24 with Medical categories.


This book offers a comprehensive, practical guide to understanding the physical and biological characteristics of proton beam radiotherapy. The application of proton beams to the treatment of solid cancers has expanded exponentially over the last decade due to their physical properties, which make it possible to administer higher doses of radiation to lesions with only a minimum dose to the surrounding healthy tissues. Accordingly, understanding the basic aspects of proton beam radiotherapy is a primary concern not only for medical physicists and radiation biologists, but also for all physicians involved in cancer treatment using proton beams. The major aspects discussed include the technique’s development background, the generation and delivery system for proton beams, physical characteristics, biological consequences, dosimetry, and future prospects in both medical physics and radiation biology in terms of effective cancer treatment. Gathering contributions from experts who provide clear and detailed information on the basics of proton beams, the book will greatly benefit not only radiological technicians, medical physicists, and physicians, but also scientists in cancer radiotherapy.



Proton Radiotherapy Accelerators


Proton Radiotherapy Accelerators
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Author : Wioletta Wieszczycka
language : en
Publisher: World Scientific
Release Date : 2001

Proton Radiotherapy Accelerators written by Wioletta Wieszczycka and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Science categories.


Hadronic radiotherapy uses particle beams to treat tumors located near critical body structures and tumors that respond poorly to conventional photon and electron beam radiotherapy. Initial research in hadronic radiotherapy was performed using accelerators built for physics research. The good results of the proton and ion therapy programs have enhanced the tendency to use protontherapy as a routine method. There are about 20 working protontherapy facilities (first, second and third generation) and more than 30 centers are planned. This book presents the first comprehensive overview of the field with a discussion on the fundamental basis of particle physics and radiobiology, as well as review of clinical and technical specifications and designs for proton radiotherapy. In particular, the current designs of proton and heavy ion accelerators, beam delivery systems, gantries, beam monitoring and dosimetry systems, control and safety systems, patient positioning and immobilization devices, and ancillary treatment facilities are widely discussed. Contents: Physical and Radiobiological Properties of Hadrons; Status of Clinical Research in Protontherapy; Hadrontherapy Facilities World-Wide; Requirements for Hadrontherapy Centers; Protontherapy Accelerators; Beam Transport and Delivery Systems; Proton Gantries; Radiation Detectors; Treatment Ancillary Facilities; Control System of the Protontherapy Center; Shielding for Proton Facility; Global Costs and Financial Analysis of the Activities of the Proton Center; Proposal of a Dedicated Protontherapy Facility. Readership: Engineers, medical physicists and physicians involved in the design and construction of radiotherapy accelerators, undergraduate and graduate students in high energy accelerator and biomedical physics, radiotherapists.