Pseudomonas Aeruginosa As An Opportunistic Pathogen
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Pseudomonas Aeruginosa As An Opportunistic Pathogen
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Author : Mario Campa
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Pseudomonas Aeruginosa As An Opportunistic Pathogen written by Mario Campa and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Assembling the latest research by an international group of contributors, this volume covers the epidemiology, pathogenesis, clinical features, and control measures of this elusive microorganism. It will provide a deeper understanding of the pathogen to physicians and surgeons caring for patients infected, or at risk of becoming infected, with Pseudomonas Aeruginosa.
Pseudomonas Aeruginosa The Opportunist
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Author : Robert B. Fick, Jr.
language : en
Publisher: CRC Press
Release Date : 1992-12-07
Pseudomonas Aeruginosa The Opportunist written by Robert B. Fick, Jr. and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-12-07 with Medical categories.
Pseudomonas aeruginosa the Opportunist provides an in depth analysis of clinically relevant pathogenetic mechanisms and selected disease states. The book presents the most current discussion of pathogenic mechanisms logically arranged from the microbiology of the Pseudomonadaceae and initial mucosal adherence, progessing to microcolony formation and release of a wide assortment of virulence factors, and closing with the contribution of host cells to the disease process. Cellular and molecular disease mechanisms are covered, including genetic regulation of virulence-associated bacterial products. Future research trends are highlighted as well. Pseudomonas aeruginosa the Opportunist is an excellent reference for bacteriologists, clinical investigators, and practicing clinicians representing a variety of specialties, including ophthalmology, pediatrics, and transplantation.
Pseudomonas Aeruginosa Biology Genetics And Host Pathogen Interactions
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Author : Dara W. Frank
language : en
Publisher: Frontiers E-books
Release Date : 2012-02-02
Pseudomonas Aeruginosa Biology Genetics And Host Pathogen Interactions written by Dara W. Frank and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-02 with categories.
The opportunistic pathogen Pseudomonas aeruginosa offers a rich variety of biologically relevant topics to explore and serves as a model system to understand the interactions of Gram-negative bacteria with human hosts. The organism adapts readily to most environments. It has a large and variable genome with a great deal of metabolic potential. P. aeruginosa encodes a variety of regulatory systems to fine tune gene expression and integrate environmental signals. This organism can infect both plants and animals and produces a plethora of enzymes and factors that can overcome host defenses. Moreover, it has the ability to change between the states of a sedentary colonizer to an invasive and highly motile organism. Clinically, the bacterium is resistant to many antibiotics making it difficult to treat and impossible to eradicate from the lungs of patients with cystic fibrosis. Intrinsic antibiotic resistance combined with an armamentarium of tissue degradative enzymes makes it imperative to possess a comprehensive understanding of the biology, genetics and pathogenesis of this organism so that novel therapeutics based on virulence product neutralization can be designed and implemented. This Research Topics issue will be devoted to updating the current understanding of P. aeruginosa systems as they relate to its different lifestyles in different environments. The underlying theme is to provide broad overviews and to integrate protein structure-function and gene regulation as it relates to the biology of this bacterium.
The Co Occurrence Of Antibiotic Resistance And Virulence In The Opportunistic Pathogen Pseudomonas Aeruginosa
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Author : Daniella Azulai
language : en
Publisher:
Release Date : 2017
The Co Occurrence Of Antibiotic Resistance And Virulence In The Opportunistic Pathogen Pseudomonas Aeruginosa written by Daniella Azulai and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Antibiotics categories.
The development of antibiotic resistance within microbial communities, especially in clinical settings, is currently an important public health issue. Human activity, such as the clinical overuse of therapeutic antibiotics, as well as the spread of antibiotics in the environment by anthropogenic pollution, is mainly responsible for this observed rise in resistance. Furthermore, it is predicted that as antibiotic resistance increases in bacterial populations, as will virulence: the capacity of these microbes to infect. This is due to the selection of antibiotic resistance, through widespread antibiotic use, co-selecting for virulence via shared cellular mechanisms between the two factors. We investigated the proposed link between antibiotic resistance and virulence by utilizing larval zebrafish and Pseudomonas aeruginosa of varying degrees of antibiotic resistance as a host-pathogen model. We were successful in developing a novel method to test virulence via static immersion. Using this technique, we found that there was no significant correlation between antibiotic resistance and virulence in the P. aeruginosa strains that we tested. We conclude that the developed method of static immersion will prove useful in understanding host-pathogen interactions, and can be utilized in future studies moving forward. Lastly, we suggest that further P. aeruginosa strains should be tested, as the lack of correlation between antibiotic resistance and virulence could be due to the small sample size used in this study. Investigating the connection between antibiotic resistance and virulence is crucial in understanding the impacts and consequences of society's current antibiotic use, and potentially in remediating the human activity responsible for the rise of antibiotic resistance in microbial populations.
Pseudomonas Aeruginosa
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Author : Alain Filloux
language : en
Publisher: Springer Nature
Release Date : 2022-10-18
Pseudomonas Aeruginosa written by Alain Filloux and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-18 with Science categories.
This book covers the wide set of well-regulated virulence factors and defense mechanisms of Pseudomonas aeruginosa focusing on stress responses and the evolution of this opportunistic human pathogen. Pseudomonas aeruginosa is responsible for one out of ten hospital infections. Additionally, this Gram-negative bacterium is accountable for persistent infections in immunocompromised individuals and the leading cause of chronic lung infections in cystic fibrosis patients. This book provides insight on the metabolic versatility of Pseudomonas aeruginosa and its mechanisms for biofilm formation that make this organism highly efficient in causing infections. The book invites the readers to learn more about the intrinsic ability of Pseudomonas aeruginosa to resist a wide variety of antimicrobial agents due to the concerted action of multidrug efflux pumps, antibiotic-degrading enzymes, and the low permeability of bacterial cellular envelopes. Particular focus is put on the evolutionary role of different types of protein-secretion systems in pathogenesis, flagella and their role in chemotaxis and surface sensing, and host-pathogen interactions. This book is a useful introduction to the field for junior scientists interested in the biology and pathogenesis of Pseudomonas aeruginosa. It is also an interesting read for advanced scientists and medical specialists working within this field, providing a broader view of the topic beyond their specific area of specialization.
Antimicrobial Drug Resistance
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Author : Douglas Mayers
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-07-14
Antimicrobial Drug Resistance written by Douglas Mayers and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-14 with Medical categories.
This ? rst edition of Antimicrobial Drug Resistance grew out of a desire by the editors and authors to have a comprehensive resource of information on antimicrobial drug resistance that encompassed the current information available for bacteria, fungi, protozoa and viruses. We believe that this information will be of value to clinicians, epidemiologists, microbiologists, virologists, parasitologists, public health authorities, medical students and fellows in training. We have endeavored to provide this information in a style which would be accessible to the broad community of persons who are concerned with the impact of drug resistance in our cl- ics and across the broader global communities. Antimicrobial Drug Resistance is divided into Volume 1 which has sections covering a general overview of drug resistance and mechanisms of drug resistance ? rst for classes of drugs and then by individual microbial agents including bacteria, fungi, protozoa and viruses. Volume 2 addresses clinical, epidemiologic and public health aspects of drug resistance along with an overview of the conduct and interpretation of speci? c drug resistance assays. Together, these two volumes offer a comprehensive source of information on drug resistance issues by the experts in each topic.
Microbial Endocrinology
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Author : Mark Lyte
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-04-06
Microbial Endocrinology written by Mark Lyte and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-06 with Medical categories.
Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. This book will introduce a new perspective to the current understanding not only of the factors that mediate the ability of microbes to cause disease, but also to the mechanisms that maintain normal homeostasis. The discovery that microbes can directly respond to neuroendocrine hormones, as evidenced by increased growth and production of virulence-associated factors, provides for a new framework with which to investigate how microorganisms interface not only with vertebrates, but also with invertebrates and even plants. The reader will learn that the neuroendocrine hormones that one most commonly associates with mammals are actually found throughout the plant, insect and microbial communities to an extent that will undoubtedly surprise many, and most importantly, how interactions between microbes and neuroendocrine hormones can influence the pathophysiology of infectious disease.
Pseudomonas Aeruginosa
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Author : Dinesh Sriramulu
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-10-02
Pseudomonas Aeruginosa written by Dinesh Sriramulu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-02 with Science categories.
Pseudomonas aeruginosa, though unfamiliar as an aggressive invader, has gained importance in the scientific community due to its association with cystic fibrosis (CF) and its ability to construct biofilms resilient to host defense. The chronic nature of CF allows this bacterium to colonize, adapt, and evolve at its own pace, thereby causing further complications in CF patients. With its huge genetic repertoire and plasticity of the genome, P. aeruginosa has been able to alter its contents by way of deletions, insertions, inversions, and so on. Therefore scientists and researchers are eager to study this bacterium in diverse and unusual niches. Written by experts from around the world, this book describes and discusses the various mechanisms of adaptation and evolution displayed by P. aeruginosa.
Pseudomonas Aeruginosa
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Author : Theerthankar Das
language : en
Publisher:
Release Date : 2021-09
Pseudomonas Aeruginosa written by Theerthankar Das and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09 with categories.
Handbook Of Biologically Active Peptides
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Author : Abba Kastin
language : en
Publisher: Elsevier
Release Date : 2011-04-28
Handbook Of Biologically Active Peptides written by Abba Kastin and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-28 with Science categories.
Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for individuals ranging from peptide researchers, to biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and to endocrinologists. Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas with which they would not ordinarily be familiar. *Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas that they would not ordinarily be familiar.*Fascinating relationships described in the book include the presence of some peptides originally found in frog skin that persist in the human human and brain where they can affect food intake and obesity.