Quantification Of Biophysical Parameters In Medical Imaging

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Quantification Of Biophysical Parameters In Medical Imaging

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Author : Ingolf Sack
language : en
Publisher: Springer Nature
Release Date : 2024-11-05

Quantification Of Biophysical Parameters In Medical Imaging written by Ingolf Sack and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-05 with Medical categories.

The second edition of this book offers six new chapters covering the latest developments in quantitative medical imaging, including artificial intelligence, MRI mapping, sonography, elastography and cardiac CT. All the other existing chapters have been updated and expanded, many with new text and figures, to reflect the rapid translation and advancement of technology in this exciting area of biomedical research. This updated edition presents fundamental knowledge on the imaging quantification of biophysical parameters for clinical diagnostic purposes. Clinical imaging scanners are considered by the authors as physical measurement systems capable of quantifying intrinsic parameters for the representation of the constitution and biophysical properties of tissues in vivo. In one respect, this approach fosters the development of new imaging methods for highly reproducible, system-independent, and quantitative biomarkers. These methods are greatly detailed in the book. Alternatively, this new edition equips the reader with a better understanding of how the physical properties of tissues interact with signal generation in medical imaging, opening up new insights into the complex and fascinating relationship between structure and function in living tissues. This updated edition is of interest to all those who recognize the limitations of clinical diagnosis based primarily on visual inspection of images, and who wish to learn more about the diagnostic potential of quantitative, biophysically-based medical imaging markers, as well as the challenges posed by the scarcity of such markers for next-generation imaging technologies.

Improving Assessments Of Hemodynamics And Vascular Disease

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Author : Magnus Ziegler
language : en
Publisher: Linköping University Electronic Press
Release Date : 2019-04-17

Improving Assessments Of Hemodynamics And Vascular Disease written by Magnus Ziegler and has been published by Linköping University Electronic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-17 with categories.

Blood vessels are more than simple pipes, passively enabling blood to pass through them. Their form and function are dynamic, changing with both aging and disease. This process involves a feedback loop wherein changes to the shape of a blood vessel affect the hemodynamics, causing yet more structural adaptation. This feedback loop is driven in part by the hemodynamic forces generated by the blood flow, and the distribution and strength of these forces appear to play a role in the initiation, progression, severity, and the outcome of vascular diseases. Magnetic Resonance Imaging (MRI) offers a unique platform for investigating both the form and function of the vascular system. The form of the vascular system can be examined using MR-based angiography, to generate detailed geometric analyses, or through quantitative techniques for measuring the composition of the vessel wall and atherosclerotic plaques. To complement these analyses, 4D Flow MRI can be used to quantify the functional aspect of the vascular system, by generating a full time-resolved three-dimensional velocity field that represents the blood flow. This thesis aims to develop and evaluate new methods for assessing vascular disease using novel hemodynamic markers generated from 4D Flow MRI and quantitative MRI data towards the larger goal of a more comprehensive non-invasive examination oriented towards vascular disease. In Paper I, we developed and evaluated techniques to quantify flow stasis in abdominal aortic aneurysms to measure this under-explored aspect of aneurysmal hemodynamics. In Paper II, the distribution and intensity of turbulence in the aorta was quantified in both younger and older men to understand how aging changes this aspect of hemodynamics. A method to quantify the stresses generated by turbulence that act on the vessel wall was developed and evaluated using simulated flow data in Paper III, and in Paper V this method was utilized to examine the wall stresses of the carotid artery. The hemodynamics of vascular disease cannot be uncoupled from the anatomical changes the vessel wall undergoes, and therefore Paper IV developed and evaluated a semi-automatic method for quantifying several aspects of vessel wall composition. These developments, taken together, help generate more valuable information from imaging data, and can be pooled together with other methods to form a more comprehensive non-invasive examination for vascular disease.

Biomechanics Of The Brain

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Author : Karol Miller
language : en
Publisher: Springer
Release Date : 2019-08-08

Biomechanics Of The Brain written by Karol Miller and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-08 with Science categories.

This new edition presents an authoritative account of the current state of brain biomechanics research for engineers, scientists and medical professionals. Since the first edition in 2011, this topic has unquestionably entered into the mainstream of biomechanical research. The book brings together leading scientists in the diverse fields of anatomy, neuroimaging, image-guided neurosurgery, brain injury, solid and fluid mechanics, mathematical modelling and computer simulation to paint an inclusive picture of the rapidly evolving field. Covering topics from brain anatomy and imaging to sophisticated methods of modeling brain injury and neurosurgery (including the most recent applications of biomechanics to treat epilepsy), to the cutting edge methods in analyzing cerebrospinal fluid and blood flow, this book is the comprehensive reference in the field. Experienced researchers as well as students will find this book useful.

Innovative Developments In Multi Modality Elastography

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Author : Simon Chatelin
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-23

Innovative Developments In Multi Modality Elastography written by Simon Chatelin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-23 with Science categories.

Implantable Technologies

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Author : Ved Srivastava
language : en
Publisher: Royal Society of Chemistry
Release Date : 2021-10-20

Implantable Technologies written by Ved Srivastava and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-20 with Science categories.

Implantable technologies allow for a sustained control over the release of pharmaceuticals into the bloodstream thereby achieving a controlled concentration with the potential to minimise side-effects while increasing patient compliance. Significant progress has been made in various alternative implantable delivery technologies, notably in intraocular and subcutaneous devices. Despite success in research and clinical studies, long-term clinical efficacy may be more limited and different aspects related to drug development and commercialization using these technologies are not well understood or practiced in the commercial setting. This book provides a comprehensive and cohesive picture of the latest in the field while also outlining the opportunities and challenges in implantable technology. Implantable Technologies: Pepties and Biologic Drug Development is an ideal reference for any postgraduate or researcher interested in utilising implantable technologies and novel routes of drug administration. The book will also be of interest to those involved in formulation and clinical application for a wide array of disease areas in addition to more established paradigms such as diabetes and pain management.

Hepatocellular Carcinoma

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Author : Brian I. Carr
language : en
Publisher: Springer
Release Date : 2016-08-26

Hepatocellular Carcinoma written by Brian I. Carr and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-26 with Medical categories.

• Hepatocellular carcinoma (HCC) used to be regarded as a rare disease. However, the increasing numbers of chronic HCC carriers in the U.S. and subsequent increased incidences of HCC seen in most large medical centers means that it is no longer an uncommon disease for gastroenterologists or oncologists to encounter and its incidence and epidemiology are changing. During this exciting time in the field of HCC basic science and clinical management, many changes are simultaneously occurring at multiple levels of our understanding and management of the disease. Suddenly, there are several new choices of therapy to offer patients. Hepatocellular Carcinoma, 3rd edition addresses this fast-changing disease and gives the reader a clearer understanding of the many mechanisms involved in carcinogenesis of the liver. This comprehensive and detailed review of how to diagnose and treat hepatocellular carcinoma is written by international leaders in the field, covering both clinical treatment choices and the basic science underlying HCC development. Updated and enhanced from the last edition in 2009, Hepatocellular Carcinoma, 3rd edition features 12 new chapters including discussion of molecular markers, molecular hepatocarcinogenesis, microenvironment, heterogeneity, the new and exciting contributions of immunotherapy, and updates on the major effective hepatitis therapies that will transform HCC incidence and perhaps also the therapy. This cutting-edge text is a vital resource and must-have for today’s hepatologists and medical and surgical oncologists. "This is a well written text and should be a good reference book for those who see patients with HCC.." - Practical Gastroenterology "...a useful tool for both physicians and surgeons with a specific interest in the management of patients with HCC." - Digestive and Liver Disease

Biophysical Techniques In Photosynthesis

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Author : Thijs Aartsma
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-01

Biophysical Techniques In Photosynthesis written by Thijs Aartsma and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-01 with Science categories.

Since the first volume on Biophysical Techniques in Photosynthesis Research, published in 1996, new experimental techniques and methods have been devised at a rapid pace. The present book is a sequel which complements the first volume by providing a comprehensive overview of the most important new techniques developed over the past ten years, especially those that are relevant for research on the mechanism and fundamental aspects of photosynthesis. The contributions are written by leading scientists in their field. The book is divided into 5 sections on Imaging, Structure, Optical and laser spectroscopy, Magnetic resonance and on Theory, respectively. Each chapter describes the basic concepts of the technique, practical applications and some of the scientific results. Possibilities and limitations from a technical as well as a scientific point of view are addressed, allowing the reader not only to recognize the potential of a particular method for his/her own quest, but to assess the resources that are required for implementation.

Medical Image Computing And Computer Assisted Intervention Miccai 2012

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Author : Nicholas Ayache
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-09-22

Medical Image Computing And Computer Assisted Intervention Miccai 2012 written by Nicholas Ayache and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-22 with Computers categories.

The three-volume set LNCS 7510, 7511, and 7512 constitutes the refereed proceedings of the 15th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2012, held in Nice, France, in October 2012. Based on rigorous peer reviews, the program committee carefully selected 252 revised papers from 781 submissions for presentation in three volumes. The first volume includes 91 papers organized in topical sections on abdominal imaging, computer-assisted interventions and robotics; computer-aided diagnosis and planning; image reconstruction and enhancement; analysis of microscopic and optical images; computer-assisted interventions and robotics; image segmentation; cardiovascular imaging; and brain imaging: structure, function and disease evolution.

Intravascular Ultrasound

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Author : Simone Balocco
language : en
Publisher: Elsevier
Release Date : 2020-06-06

Intravascular Ultrasound written by Simone Balocco and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-06 with Technology & Engineering categories.

Intravascular Ultrasound: From Acquisition to Advanced Quantitative Analysis covers topics of the whole imaging pipeline, ranging from the definition of the clinical problem and image acquisition systems to image processing and analysis, including the assisted clinical-decision making procedures and treatment planning (stent deployment and follow up). Atherosclerosis, a disease of the vessel wall that produces vessel narrowing and obstruction, is the major cause of cardiovascular diseases, such as heart attack or stroke. This book covers all aspects of this imaging tool that allows for the visualization of internal vessel structures and the quantification and characterization of coronary plaque. - Provides an introduction to the clinical workflow and current challenges in endovascular interventions - Presents a review of the state-of-the-art methodologies in IVUS imaging and their applications - Includes a rich analysis of the current and potential future connections between the academic, clinical and industrial fields

Brain Mapping

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Author :
language : en
Publisher: Academic Press
Release Date : 2015-02-14

Brain Mapping written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-14 with Science categories.

Brain Mapping: A Comprehensive Reference, Three Volume Set offers foundational information for students and researchers across neuroscience. With over 300 articles and a media rich environment, this resource provides exhaustive coverage of the methods and systems involved in brain mapping, fully links the data to disease (presenting side by side maps of healthy and diseased brains for direct comparisons), and offers data sets and fully annotated color images. Each entry is built on a layered approach of the content – basic information for those new to the area and more detailed material for experienced readers. Edited and authored by the leading experts in the field, this work offers the most reputable, easily searchable content with cross referencing across articles, a one-stop reference for students, researchers and teaching faculty. Broad overview of neuroimaging concepts with applications across the neurosciences and biomedical research Fully annotated color images and videos for best comprehension of concepts Layered content for readers of different levels of expertise Easily searchable entries for quick access of reputable information Live reference links to ScienceDirect, Scopus and PubMed