Quantification Validation And Uncertainty In Analytical Sciences

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Quantification Validation And Uncertainty In Analytical Sciences
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Author : Max Feinberg
language : en
Publisher: John Wiley & Sons
Release Date : 2024-02-12
Quantification Validation And Uncertainty In Analytical Sciences written by Max Feinberg and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-12 with Science categories.
Quantification, Validation and Uncertainty in Analytical Sciences Companion guide explaining all processes in measuring uncertainty in quantitative analytical results Quantification, Validation and Uncertainty in Analytical Sciences provides basic and expert knowledge by building on the sequence of operations starting from the quantification in analytical sciences by defining the analyte and linking it to the calibration function. Proposing a comprehensive approach to MU (Measurement Uncertainty) estimation, it empowers the reader to apply Method Accuracy Profile (MAP) efficiently as a statistical tool in measuring uncertainty. The text elucidates several examples and template worksheets explaining the theoretical aspects of the procedure and includes novel method validation procedures that can accurately estimate the data obtained in measurements. It also enables the reader to provide practical insights to improve decision making by accurately evaluating and comparing different analytical methods. Brings together an interdisciplinary approach with statistical tools and algorithms applied in analytical chemistry and written by two international experts with long-standing experience in the field of Analytical measurements and Uncertainty, Quantification, Validation and Uncertainty in Analytical Sciences includes information on: The know-how of methods in an analytical laboratory, effective usage of a spurious measurement and methods to estimate errors. Quantification, calibration, precision, trueness, MAP addons, estimating MU for analytical sciences, and uncertainty functions Employing measurement uncertainty, sampling uncertainty, quantification limits, and sample conformity assessment Decision making, uncertainty and standard addition method, and accuracy profile for method comparison Quantification, Validation and Uncertainty in Analytical Sciences is an ideal resource for every individual quantifying or studying analytes. With several chapters dedicated to MU’s practical use in decision making demonstrating its advantages, the book is primarily intended for professional analysts, although researchers and students will also find it of interest.
Verification And Validation In Scientific Computing
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Author : William L. Oberkampf
language : en
Publisher: Cambridge University Press
Release Date : 2010-10-14
Verification And Validation In Scientific Computing written by William L. Oberkampf and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-14 with Computers categories.
Advances in scientific computing have made modelling and simulation an important part of the decision-making process in engineering, science, and public policy. This book provides a comprehensive and systematic development of the basic concepts, principles, and procedures for verification and validation of models and simulations. The emphasis is placed on models that are described by partial differential and integral equations and the simulations that result from their numerical solution. The methods described can be applied to a wide range of technical fields, from the physical sciences, engineering and technology and industry, through to environmental regulations and safety, product and plant safety, financial investing, and governmental regulations. This book will be genuinely welcomed by researchers, practitioners, and decision makers in a broad range of fields, who seek to improve the credibility and reliability of simulation results. It will also be appropriate either for university courses or for independent study.
Handbook Of Analytical Validation
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Author : Michael E. Swartz
language : en
Publisher: CRC Press
Release Date : 2012-04-24
Handbook Of Analytical Validation written by Michael E. Swartz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-24 with Medical categories.
Written for practitioners in both the drug and biotechnology industries, this handbook carefully compiles the current regulatory requirements to correctly and properly validate a new or modified analytical method. The Handbook of Analytical Validation is designed to teach readers how to fully and correctly adapt new or modified analytical methods to meet regulatory requirements. The contents offer the latest regulatory requirements for submitting applications for new drugs or other applications, as regards analytical method validation. The chapters apply to both small molecules in the conventional pharmaceutical industry, as well the biotech industry.
Quality Assurance In Analytical Chemistry
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Author : Bernd W. Wenclawiak
language : en
Publisher: Springer
Release Date : 2013-12-20
Quality Assurance In Analytical Chemistry written by Bernd W. Wenclawiak and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-20 with Science categories.
The application of Quality Assurance (QA) techniques has led to major improvements in the quality of many products and services. Fortunately these techniques have been well documented in the form of guides and standards and nowhere more so than in the area of measurement and testing, particularly chemical analysis. Training of analysts and potential analysts in quality assurance techniques is a major task for universities and industrial and government laboratories. Re-training is also necessary since the quest for improvements in quality seems to be never ending. The purpose of this book is to provide training material in the convenient form of PowerPoint slides with notes giving further details on the contents of the slides. Experts in the relevant topic, who have direct experience of lecturing on or utilising its contents, have written each chapter. Almost every aspect of QA is covered from basic fundamentals such as statistics, uncertainty and traceability, which are applicable to all types of measurement, through specific guidance on method validation, use of reference materials and control charts. These are all set in the context of total quality management, certification and accreditation. Each chapter is intended to be self-contained and inevitably this leads to some duplication and cross-references are given if there is more detailed treatment in other chapters.
Measurement Uncertainty In Chemical Analysis
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Author : Paul De Bièvre
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Measurement Uncertainty In Chemical Analysis written by Paul De Bièvre and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
It is now becoming recognized in the measurement community that it is as important to communicate the uncertainty related to a specific measurement as it is to report the measurement itself. Without knowing the uncertainty, it is impossible for the users of the result to know what confidence can be placed in it; it is also impossible to assess the comparability of different measurements of the same parameter. This volume collects 20 outstanding papers on the topic, mostly published from 1999-2002 in the journal "Accreditation and Quality Assurance." They provide the rationale for why it is important to evaluate and report the uncertainty of a result in a consistent manner. They also describe the concept of uncertainty, the methodology for evaluating uncertainty, and the advantages of using suitable reference materials. Finally, the benefits to both the analytical laboratory and the user of the results are considered.
Encyclopedia Of Analytical Science
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Author :
language : en
Publisher: Elsevier
Release Date : 2019-04-02
Encyclopedia Of Analytical Science written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-02 with Science categories.
The third edition of the Encyclopedia of Analytical Science, Ten Volume Set is a definitive collection of articles covering the latest technologies in application areas such as medicine, environmental science, food science and geology. Meticulously organized, clearly written and fully interdisciplinary, the Encyclopedia of Analytical Science, Ten Volume Set provides foundational knowledge across the scope of modern analytical chemistry, linking fundamental topics with the latest methodologies. Articles will cover three broad areas: analytical techniques (e.g., mass spectrometry, liquid chromatography, atomic spectrometry); areas of application (e.g., forensic, environmental and clinical); and analytes (e.g., arsenic, nucleic acids and polycyclic aromatic hydrocarbons), providing a one-stop resource for analytical scientists. Offers readers a one-stop resource with access to information across the entire scope of modern analytical science Presents articles split into three broad areas: analytical techniques, areas of application and and analytes, creating an ideal resource for students, researchers and professionals Provides concise and accessible information that is ideal for non-specialists and readers from undergraduate levels and higher
Topics In Model Validation And Uncertainty Quantification Volume 5
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Author : Todd Simmermacher
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-05-30
Topics In Model Validation And Uncertainty Quantification Volume 5 written by Todd Simmermacher and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-30 with Technology & Engineering categories.
Topics in Model Validation and Uncertainty Quantification, Volume : Proceedings of the 31st IMAC, A Conference and Exposition on Structural Dynamics, 2013, the fifth volume of seven from the Conference, brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on fundamental and applied aspects of Structural Dynamics, including papers on: Uncertainty Quantification & Propagation in Structural Dynamics Robustness to Lack of Knowledge in Design Model Validation
Calibration In Analytical Science
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Author : Paweł Kościelniak
language : en
Publisher: John Wiley & Sons
Release Date : 2023-02-13
Calibration In Analytical Science written by Paweł Kościelniak and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-13 with Science categories.
Calibration in Analytical Science Designed to help analytical chemists save time and money by selecting the best calibration method in a quality control, substance monitoring, or research setting Univariate analytical calibration is a vital step in every chemical procedure that involves determining the identity or concentration of a particular substance. Depending on the type of instrument and measurement, analytical chemists need to follow different calibration strategies and protocols to ensure their instruments yield accurate readings. Calibration in Analytical Science systematically classifies and describes a wide range of calibration methods and procedures based on mathematical and empirical models for use in qualitative and quantitative analysis. Focusing on the chemical aspects of analytical calibration, this much-needed reference uses a set of equipment-independent terms and definitions that are easily transferable to the calibration strategies of any analytical process. The theoretical basis for calibration of each analytical mode is described and applied to common analytical tasks of increasing levels of difficulty and complexity. Throughout the book, the author illustrates how to combine different calibration approaches to create new calibration strategies with extended capabilities. Describes different calibration methods and procedures for determining the nature and quantity of sample components in different ways Classifies various calibration methods in both qualitative and quantitative analysis Demonstrates how the random and systematic errors of an analytical method can be minimized by the proper calibration strategy Discusses current theoretical and methodological questions in calibration research Highlights how calibration approaches can diagnose, evaluate, and eliminate analytical errors Includes a concluding chapter on the contribution of calibration to the greening of analytical chemistry Calibration in Analytical Science: Methods and Procedures is a must-have reference for analytical chemists working in academia and industry, chemists of various specialties involved in chemical analysis, and advanced undergraduate and graduate students taking courses in advanced analytical chemistry.
Metrology In Chemistry
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Author : Ewa Bulska
language : en
Publisher: Springer
Release Date : 2018-09-29
Metrology In Chemistry written by Ewa Bulska and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-29 with Science categories.
In this concise book, the author presents the essentials every chemist needs to know about how to obtain reliable measurement results. Starting with the basics of metrology and the metrological infrastructure, all relevant topics – such as traceability, calibration, chemical reference materials, validation and uncertainty – are covered. In addition, key aspects of laboratory management, including quality management, inter-laboratory comparisons, proficiency testing, and accreditation, are addressed.
Quality Assurance In Analytical Chemistry
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Author : Elizabeth Prichard
language : en
Publisher: John Wiley & Sons
Release Date : 2007-09-27
Quality Assurance In Analytical Chemistry written by Elizabeth Prichard and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-27 with Science categories.
The issue of quality assurance in the analytical chemistry laboratory has become of great importance in recent years. Quality Assurance in Analytical Chemistry introduces the reader to the whole concept of quality assurance. It discusses how all aspects of chemical analysis, from sampling and method selection to choice of equipment and the taking and reporting of measurements affect the quality of analytical data. Finally, the implementation and use of quality systems are covered.