Quantitative Methods In Proteomics
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Quantitative Methods In Proteomics
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Author : Katrin Marcus
language : en
Publisher: Humana
Release Date : 2022-05-20
Quantitative Methods In Proteomics written by Katrin Marcus and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-20 with Science categories.
This second edition provides new and updated methods on the principles underlying modern protein analysis, from statistical issues to gel-based and mass spectrometry-based applications. Chapters detail protein quantification as basis for realisation of quantitative studies, gel-based and mass spectrometry-based quantification techniques, TMT, IPTL, PRM, MALDI Imaging, SILAC, PTM analysis, DIA, cross-linking, and the up-to-date topics of software and data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Quantitative Methods in Proteomics, Second Edition aims to provide comprehensive and competent overview in the important and still growing field of quantitative proteomics.
Computational And Statistical Methods For Protein Quantification By Mass Spectrometry
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Author : Ingvar Eidhammer
language : en
Publisher: John Wiley & Sons
Release Date : 2013-02-11
Computational And Statistical Methods For Protein Quantification By Mass Spectrometry written by Ingvar Eidhammer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-11 with Mathematics categories.
The definitive introduction to data analysis in quantitative proteomics This book provides all the necessary knowledge about mass spectrometry based proteomics methods and computational and statistical approaches to pursue the planning, design and analysis of quantitative proteomics experiments. The author’s carefully constructed approach allows readers to easily make the transition into the field of quantitative proteomics. Through detailed descriptions of wet-lab methods, computational approaches and statistical tools, this book covers the full scope of a quantitative experiment, allowing readers to acquire new knowledge as well as acting as a useful reference work for more advanced readers. Computational and Statistical Methods for Protein Quantification by Mass Spectrometry: Introduces the use of mass spectrometry in protein quantification and how the bioinformatics challenges in this field can be solved using statistical methods and various software programs. Is illustrated by a large number of figures and examples as well as numerous exercises. Provides both clear and rigorous descriptions of methods and approaches. Is thoroughly indexed and cross-referenced, combining the strengths of a text book with the utility of a reference work. Features detailed discussions of both wet-lab approaches and statistical and computational methods. With clear and thorough descriptions of the various methods and approaches, this book is accessible to biologists, informaticians, and statisticians alike and is aimed at readers across the academic spectrum, from advanced undergraduate students to post doctorates entering the field.
Quantitative Methods In Pharmaceutical Research And Development
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Author : Olga V. Marchenko
language : en
Publisher: Springer Nature
Release Date : 2020-09-24
Quantitative Methods In Pharmaceutical Research And Development written by Olga V. Marchenko and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-24 with Medical categories.
This contributed volume presents an overview of concepts, methods, and applications used in several quantitative areas of drug research, development, and marketing. Chapters bring together the theories and applications of various disciplines, allowing readers to learn more about quantitative fields, and to better recognize the differences between them. Because it provides a thorough overview, this will serve as a self-contained resource for readers interested in the pharmaceutical industry, and the quantitative methods that serve as its foundation. Specific disciplines covered include: Biostatistics Pharmacometrics Genomics Bioinformatics Pharmacoepidemiology Commercial analytics Operational analytics Quantitative Methods in Pharmaceutical Research and Development is ideal for undergraduate students interested in learning about real-world applications of quantitative methods, and the potential career options open to them. It will also be of interest to experts working in these areas.
Routledge International Handbook Of Advanced Quantitative Methods In Nursing Research
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Author : Susan J Henly
language : en
Publisher: Routledge
Release Date : 2015-07-24
Routledge International Handbook Of Advanced Quantitative Methods In Nursing Research written by Susan J Henly and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-24 with Medical categories.
Designed to support global development of nursing science, the Routledge International Handbook of Advanced Quantitative Methods in Nursing Research provides a new, comprehensive, and authoritative treatment of advanced quantitative methods for nursing research. Incorporating past approaches that have served as the foundation for the science, this cutting edge book also explores emerging approaches that will shape its future. Divided into six parts, it covers: -the domain of nursing science - measurement—classical test theory, IRT, clinimetrics, behavioral observation, biophysical measurement -models for prediction and explanation—SEM, general growth mixture models, hierarchical models, analysis of dynamic systems -intervention research—theory-based interventions, causality, third variables, pilot studies, quasi-experimental design, joint models for longitudinal data and time to event -e-science—DIKW paradigm, big data, data mining, omics, FMRI -special topics—comparative effectiveness and meta-analysis, patient safety, economics research in nursing, mixed methods, global research dissemination Written by a distinguished group of international nursing scientists, scientists from related fields, and methodologists, the Handbook is the ideal reference for everyone involved in nursing science, whether they are graduate students, academics, editors and reviewers, or clinical investigators.
Mass Spectrometry Based Chemical Proteomics
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Author : W. Andy Tao
language : en
Publisher: John Wiley & Sons
Release Date : 2019-07-10
Mass Spectrometry Based Chemical Proteomics written by W. Andy Tao and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-10 with Science categories.
PROVIDES STRATEGIES AND CONCEPTS FOR UNDERSTANDING CHEMICAL PROTEOMICS, AND ANALYZING PROTEIN FUNCTIONS, MODIFICATIONS, AND INTERACTIONS—EMPHASIZING MASS SPECTROMETRY THROUGHOUT Covering mass spectrometry for chemical proteomics, this book helps readers understand analytical strategies behind protein functions, their modifications and interactions, and applications in drug discovery. It provides a basic overview and presents concepts in chemical proteomics through three angles: Strategies, Technical Advances, and Applications. Chapters cover those many technical advances and applications in drug discovery, from target identification to validation and potential treatments. The first section of Mass Spectrometry-Based Chemical Proteomics starts by reviewing basic methods and recent advances in mass spectrometry for proteomics, including shotgun proteomics, quantitative proteomics, and data analyses. The next section covers a variety of techniques and strategies coupling chemical probes to MS-based proteomics to provide functional insights into the proteome. In the last section, it focuses on using chemical strategies to study protein post-translational modifications and high-order structures. Summarizes chemical proteomics, up-to-date concepts, analysis, and target validation Covers fundamentals and strategies, including the profiling of enzyme activities and protein-drug interactions Explains technical advances in the field and describes on shotgun proteomics, quantitative proteomics, and corresponding methods of software and database usage for proteomics Includes a wide variety of applications in drug discovery, from kinase inhibitors and intracellular drug targets to the chemoproteomics analysis of natural products Addresses an important tool in small molecule drug discovery, appealing to both academia and the pharmaceutical industry Mass Spectrometry-Based Chemical Proteomics is an excellent source of information for readers in both academia and industry in a variety of fields, including pharmaceutical sciences, drug discovery, molecular biology, bioinformatics, and analytical sciences.
Recent Advances In Quantitative Methods In Cancer And Human Health Risk Assessment
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Author : Lutz Edler
language : en
Publisher: John Wiley & Sons
Release Date : 2005-05-27
Recent Advances In Quantitative Methods In Cancer And Human Health Risk Assessment written by Lutz Edler and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-27 with Mathematics categories.
Human health risk assessment involves the measuring of risk of exposure to disease, with a view to improving disease prevention. Mathematical, biological, statistical, and computational methods play a key role in exposure assessment, hazard assessment and identification, and dose-response modelling. Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment is a comprehensive text that accounts for the wealth of new biological data as well as new biological, toxicological, and medical approaches adopted in risk assessment. It provides an authoritative compendium of state-of-the-art methods proposed and used, featuring contributions from eminent authors with varied experience from academia, government, and industry. Provides a comprehensive summary of currently available quantitative methods for risk assessment of both cancer and non-cancer problems. Describes the applications and the limitations of current mathematical modelling and statistical analysis methods (classical and Bayesian). Includes an extensive introduction and discussion to each chapter. Features detailed studies of risk assessments using biologically-based modelling approaches. Discusses the varying computational aspects of the methods proposed. Provides a global perspective on human health risk assessment by featuring case studies from a wide range of countries. Features an extensive bibliography with links to relevant background information within each chapter. Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment will appeal to researchers and practitioners in public health & epidemiology, and postgraduate students alike. It will also be of interest to professionals working in risk assessment agencies.
Recent Advances In Proteomics Research
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Author : Sameh Magdeldin
language : en
Publisher: BoD – Books on Demand
Release Date : 2015-11-11
Recent Advances In Proteomics Research written by Sameh Magdeldin and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-11 with Science categories.
Proteomics refers to the entire complement of proteins, including modification. This promising discipline has enabled us to study proteins from a massive and comprehensive point of view. The book Recent Advances in Proteomics Research describes in five sections some of the applications of proteomics. This fine research has been written by leading experts worldwide. This book is aimed mainly at those interested in proteins and in the field of proteins, particularly biochemists, biologists, pharmacists, advanced graduate students and postgraduate researchers.
Methods In Animal Proteomics
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Author : Philip Whitfield
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-13
Methods In Animal Proteomics written by Philip Whitfield and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-13 with Science categories.
The study of proteomics provides researchers with a better understanding of disease and physiological processes in animals. Methods in Animal Proteomics will provide animal scientists and veterinarians currently researching these topics in domestic animals a firm foundation in the basics of proteomics methodology, while also reviewing important advances that will be of interest to established researchers in the field. Chapters will provide practical information on a range of topics including protein identification and separation, bioinformatics, and applications to disease and reproduction research. This text will be written by leading international proteomics experts and essential for researchers in the fields of animal biology and veterinary medicine.
Pharmacoproteomics
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Author : Seth K. Amponsah
language : en
Publisher: Springer Nature
Release Date : 2024-09-01
Pharmacoproteomics written by Seth K. Amponsah and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-01 with Science categories.
This book gives an overview of pharmacoproteomics and its clinical applications, as well as the latest information on drug mechanisms at the proteome level, the relationship between proteomics and toxicity or resistance, and how proteomics aid in discovery of new drug targets. The book also highlights recent advances in analytical methods, analysis, and interpretation of pharmacoproteomic data. Pharmacoproteomics: Recent Trends and Applications is an ideal book for those working in pharmaceutical industries, as well as scientists, health care professionals, and researchers who work in the field of genomics, pharmacology, pharmacokinetics, toxicology, and pharmaceutical chemistry.
Plant Proteomics
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Author : Jesus V Jorrin-Novo
language : en
Publisher: Humana
Release Date : 2021-06-11
Plant Proteomics written by Jesus V Jorrin-Novo and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-11 with categories.